{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:38:22Z","timestamp":1771061902757,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"46","license":[{"start":{"date-parts":[[2000,11,2]],"date-time":"2000-11-02T00:00:00Z","timestamp":973123200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2000,11,2]],"date-time":"2000-11-02T00:00:00Z","timestamp":973123200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2000,11,2]]},"DOI":"10.1038\/sj.onc.1203902","type":"journal-article","created":{"date-parts":[[2002,9,4]],"date-time":"2002-09-04T19:52:09Z","timestamp":1031169129000},"page":"5281-5290","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":84,"title":["A possible role for centrosome overduplication in radiation-induced cell death"],"prefix":"10.1038","volume":"19","author":[{"given":"Norihiro","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Mizumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikaru","family":"Ueno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohji A","family":"Minamishima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L","family":"Farber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2000,11,2]]},"reference":[{"key":"BF1203902_CR1","unstructured":"Bae I, Fan S, Bhatia K, Kohn KW, Fornace Jr AJ and O'Connor PM. . 1995 Cancer Res. 55: 2387\u20132392."},{"key":"BF1203902_CR2","doi-asserted-by":"crossref","unstructured":"Balczon R, Bao L, Zimmer WE, Brown K, Zinkowski RP and Brinkley BR. . 1995 J. Cell. Biol., 130: 105\u2013115.","DOI":"10.1083\/jcb.130.1.105"},{"key":"BF1203902_CR3","doi-asserted-by":"crossref","unstructured":"Bissonnette N and Hunting DJ. . 1998 Oncogene 16: 3461\u20133469.","DOI":"10.1038\/sj.onc.1201899"},{"key":"BF1203902_CR4","doi-asserted-by":"crossref","unstructured":"Brinkley BR. . 1985 Ann. Rev. Cell Biol. 1: 145\u2013172.","DOI":"10.1146\/annurev.cb.01.110185.001045"},{"key":"BF1203902_CR5","doi-asserted-by":"crossref","unstructured":"Brinkley BR and Goepfert TM. . 1998 Cell Motil. Cytoskel. 41: 281\u2013288.","DOI":"10.1002\/(SICI)1097-0169(1998)41:4<281::AID-CM1>3.0.CO;2-C"},{"key":"BF1203902_CR6","doi-asserted-by":"crossref","unstructured":"Carroll PE, Okuda M, Horn HF, Biddinger P, Stambrook PJ, Gleich LL, Li YQ, Tarapore P and Fukasawa K. . 1999 Oncogene 18: 1935\u20131944.","DOI":"10.1038\/sj.onc.1202515"},{"key":"BF1203902_CR7","doi-asserted-by":"crossref","unstructured":"Chan TA, Hermeking H, Lengauer C, Kinzler KW and Vogelstein B. . 1999 Nature 401: 616\u2013620.","DOI":"10.1038\/44188"},{"key":"BF1203902_CR8","unstructured":"Chang BD, Broude EV, Dokmanovic M, Zhu H, Ruth A, Xuan Y, Kandel ES, Lausch E, Christov K and Roninson IB. . 1999a Cancer Res. 59: 3761\u20133767."},{"key":"BF1203902_CR9","doi-asserted-by":"crossref","unstructured":"Chang BD, Xuan Y, Broude EV, Zhu H, Schott B, Fang J and Roninson IB. . 1999b Oncogene 18: 4808\u20134818.","DOI":"10.1038\/sj.onc.1203078"},{"key":"BF1203902_CR10","doi-asserted-by":"crossref","unstructured":"Chang WP and Little JB. . 1991 Int. J. Radiat. Biol. 60: 483\u2013496.","DOI":"10.1080\/09553009114552331"},{"key":"BF1203902_CR11","doi-asserted-by":"crossref","unstructured":"Dewey WC, Ling CC and Meyn RE. . 1995 Int. J. Radiat. Oncol. Biol. Phys. 33: 781\u2013796.","DOI":"10.1016\/0360-3016(95)00214-8"},{"key":"BF1203902_CR12","doi-asserted-by":"crossref","unstructured":"Doxsey S. . 1998 Nat. Genet. 20: 104\u2013106.","DOI":"10.1038\/2392"},{"key":"BF1203902_CR13","doi-asserted-by":"crossref","unstructured":"Fukasawa K, Choi T, Kuriyama R, Rulong S and Vande Woude GF. . 1996 Science 271: 1744\u20131747.","DOI":"10.1126\/science.271.5256.1744"},{"key":"BF1203902_CR14","doi-asserted-by":"crossref","unstructured":"Fukasawa K, Wiener F, Vande Woude GF and Mai S. . 1997 Oncogene 15: 1295\u20131302.","DOI":"10.1038\/sj.onc.1201482"},{"key":"BF1203902_CR15","doi-asserted-by":"crossref","unstructured":"Gard DL, Hafezi S, Zhang T and Doxsey SJ. . 1990 J. Cell Biol. 110: 2033\u20132042.","DOI":"10.1083\/jcb.110.6.2033"},{"key":"BF1203902_CR16","doi-asserted-by":"crossref","unstructured":"Han Z, Chatterjee D, He DM, Early J, Pantazis P, Wyche JH and Hendrickson EA. . 1995 Mol. Cell. Biol. 15: 5849\u20135857.","DOI":"10.1128\/MCB.15.11.5849"},{"key":"BF1203902_CR17","doi-asserted-by":"crossref","unstructured":"Hendry JH and West CM. . 1997 Int. J. Radiat. Biol. 71: 709\u2013719.","DOI":"10.1080\/095530097143716"},{"key":"BF1203902_CR18","doi-asserted-by":"crossref","unstructured":"Hinchcliffe EH, Li C, Thompson EA, Maller JL and Sluder G. . 1999 Science 283: 851\u2013854.","DOI":"10.1126\/science.283.5403.851"},{"key":"BF1203902_CR19","doi-asserted-by":"crossref","unstructured":"Hollander MC, Sheikh MS, Bulavin DV, Lundgren K, Augeri-Henmueller L, Shehee R, Molinaro TA, Kim KE, Tolosa E, Ashwell JD, Rosenberg MP, Zhan Q, Fernandez-Salguero PM, Morgan WF, Deng CX and Fornace Jr AJ. . 1999 Nat. Genet., 23: 176\u2013184.","DOI":"10.1038\/13802"},{"key":"BF1203902_CR20","doi-asserted-by":"crossref","unstructured":"Jonathan EC, Bernhard EJ and McKenna WG. . 1999 Curr. Opin. Chem. Biol. 3: 77\u201383.","DOI":"10.1016\/S1367-5931(99)80014-3"},{"key":"BF1203902_CR21","unstructured":"Kastan MB, Onyekwere O, Sidransky D, Vogelstein B and Craig RW. . 1991 Cancer Res. 51: 6304\u20136311."},{"key":"BF1203902_CR22","doi-asserted-by":"crossref","unstructured":"Kellogg DR, Moritz M and Alberts BM. . 1994 Ann. Rev. Biochem. 63: 639\u2013674.","DOI":"10.1146\/annurev.bi.63.070194.003231"},{"key":"BF1203902_CR23","doi-asserted-by":"crossref","unstructured":"Kuo KK, Sato N, Mizumoto K, Maehara N, Yonemasu H, Ker CG, Sheen PC and Tanaka M. . 2000 Hepatology 31: 59\u201364.","DOI":"10.1002\/hep.510310112"},{"key":"BF1203902_CR24","unstructured":"Kusumoto M, Ogawa T, Mizumoto K, Ueno H, Niiyama H, Sato N, Nakamura M and Tanaka M. . 1999 Clin. Cancer Res. 5: 2140\u20132147."},{"key":"BF1203902_CR25","doi-asserted-by":"crossref","unstructured":"Lacey KR, Jackson PK and Stearns T. . 1999 Proc. Natl. Acad. Sci. USA 96: 2817\u20132822.","DOI":"10.1073\/pnas.96.6.2817"},{"key":"BF1203902_CR26","doi-asserted-by":"crossref","unstructured":"Li R, Waga S, Hannon GJ, Beach D and Stillman B. . 1994 Nature 371: 534\u2013537.","DOI":"10.1038\/371534a0"},{"key":"BF1203902_CR27","doi-asserted-by":"crossref","unstructured":"Lingle WL, Lutz WH, Ingle JN, Maihle NJ and Salisbury JL. . 1998 Proc. Natl. Acad. Sci. USA, 95: 2950\u20132955.","DOI":"10.1073\/pnas.95.6.2950"},{"key":"BF1203902_CR28","unstructured":"Lock RB and Stribinskiene L. . 1996 Cancer Res. 56: 4006\u20134012."},{"key":"BF1203902_CR29","doi-asserted-by":"crossref","unstructured":"Mantel C, Braun SE, Reis S, Henegariu O, Liu L, Hangoc G and Broxmeyer HE. . 1999 Blood 93: 1390\u20131398.","DOI":"10.1182\/blood.V93.4.1390"},{"key":"BF1203902_CR30","doi-asserted-by":"crossref","unstructured":"Matsumoto Y, Hayashi K and Nishida E. . 1999 Curr. Biol. 9: 429\u2013432.","DOI":"10.1016\/S0960-9822(99)80191-2"},{"key":"BF1203902_CR31","unstructured":"McDonald ER, Wu, GS, Waldman T and El-Deiry WS. . 1996 Cancer Res. 56: 2250\u20132255."},{"key":"BF1203902_CR32","doi-asserted-by":"crossref","unstructured":"Muller WU, Nusse M, Miller BM, Slavotinek A, Viaggi S and Streffer C. . 1996 Mutat. Res. 366: 163\u2013169.","DOI":"10.1016\/S0165-1110(96)90037-8"},{"key":"BF1203902_CR33","unstructured":"Pihan GA, Purohit A, Wallace J, Knecht H, Woda B, Quesenberry P and Doxsey SJ. . 1998 Cancer Res. 58: 3974\u20133985."},{"key":"BF1203902_CR34","doi-asserted-by":"crossref","unstructured":"Raff JW and Glover DM. . 1988 J. Cell Biol. 107: 2009\u20132019.","DOI":"10.1083\/jcb.107.6.2009"},{"key":"BF1203902_CR35","doi-asserted-by":"crossref","unstructured":"Sablina AA, Ilyinskaya GV, Rubtsova SN, Agapova LS, Chumakov PM and Kopnin BP. . 1998 J. Cell Sci. 111: 977\u2013984.","DOI":"10.1242\/jcs.111.7.977"},{"key":"BF1203902_CR36","unstructured":"Sato N, Mizumoto K, Nakamura M, Nakamura K, Kusumoto M, Niiyama H, Ogawa T and Tanaka M. . 1999 Clin. Cancer Res. 5: 963\u2013970."},{"key":"BF1203902_CR37","doi-asserted-by":"crossref","unstructured":"Sato N, Mizumoto K, Nakamura M and Tanaka M. . 2000 Exp. Cell Res. 255: 321\u2013326.","DOI":"10.1006\/excr.1999.4797"},{"key":"BF1203902_CR38","doi-asserted-by":"crossref","unstructured":"Schwartz D, Almog N, Peled A, Goldfinger N and Rotter V. . 1997 Oncogene 15: 2597\u20132607.","DOI":"10.1038\/sj.onc.1201436"},{"key":"BF1203902_CR39","doi-asserted-by":"crossref","unstructured":"Tutt A, Gabriel A, Bertwistle D, Connor F, Paterson H, Peacock J, Ross G and Ashworth A. . 1999 Curr. Biol. 9: 1107\u20131110.","DOI":"10.1016\/S0960-9822(99)80479-5"},{"key":"BF1203902_CR40","doi-asserted-by":"crossref","unstructured":"Ueno H, Li JJ, Tomita H, Yamamoto H, Pan Y, Kanegae Y, Saito I and Takeshita A. . 1995 Arterioscl. Thromb. Vasc. Biol. 15: 2246\u20132253.","DOI":"10.1161\/01.ATV.15.12.2246"},{"key":"BF1203902_CR41","doi-asserted-by":"crossref","unstructured":"Ueno H, Masuda S, Nishio S, Li JJ, Yamamoto H and Takeshita A. . 1997 Ann. NY. Acad. Sci., 811: 401\u2013411.","DOI":"10.1111\/j.1749-6632.1997.tb52020.x"},{"key":"BF1203902_CR42","doi-asserted-by":"crossref","unstructured":"Urbani L and Stearns T. . 1999 Curr. Biol. 9: R315\u2013R317.","DOI":"10.1016\/S0960-9822(99)80201-2"},{"key":"BF1203902_CR43","doi-asserted-by":"crossref","unstructured":"Wang Y, Blandino G and Givol D. . 1999 Oncogene 18: 2643\u20132649.","DOI":"10.1038\/sj.onc.1202632"},{"key":"BF1203902_CR44","doi-asserted-by":"crossref","unstructured":"Weber RG, Bridger JM, Benner A, Weisenberger D, Ehemann V, Reifenberger G and Lichter P. . 1998 Cytogent. Cell Genet. 83: 266\u2013269.","DOI":"10.1159\/000015168"},{"key":"BF1203902_CR45","doi-asserted-by":"crossref","unstructured":"Winey M. . 1996 Curr. Biol. 6: 962\u2013964.","DOI":"10.1016\/S0960-9822(02)00639-5"},{"key":"BF1203902_CR46","doi-asserted-by":"crossref","unstructured":"Xu X, Weaver Z, Linke SP, Li C, Gotay J, Wang XW, Harris CC, Reid T and Deng CX. . 1999 Mol. Cell. 3: 389\u2013395.","DOI":"10.1016\/S1097-2765(00)80466-9"},{"key":"BF1203902_CR47","doi-asserted-by":"crossref","unstructured":"Zhang L, Mizumoto K, Sato N, Ogawa T, Kusumoto M, Niiyama H and Tanaka M. . 1999 Cancer Lett. 142: 129\u2013137.","DOI":"10.1016\/S0304-3835(99)00107-X"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1203902.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1203902","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1203902.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T01:30:42Z","timestamp":1647912642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1203902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11,2]]},"references-count":47,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2000,11,2]]}},"alternative-id":["BF1203902"],"URL":"https:\/\/doi.org\/10.1038\/sj.onc.1203902","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,11,2]]},"assertion":[{"value":"29 June 2000","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2000","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2000","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 November 2000","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}