{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T13:09:17Z","timestamp":1792242557810,"version":"4.4.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1038\/ajg.2010.415","type":"journal-article","created":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T10:46:40Z","timestamp":1288090000000},"page":"432-442","source":"Crossref","is-referenced-by-count":158,"title":["Meat Consumption and Risk of Esophageal and Gastric Cancer in a Large Prospective Study"],"prefix":"10.14309","volume":"106","author":[{"given":"Amanda J","family":"Cross","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal D","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiansong","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary H","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert R","family":"Hollenbeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Schatzkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian C","family":"Abnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R4-9-20210210","doi-asserted-by":"crossref","first-page":"354","DOI":"10.3748\/wjg.v12.i3.354","article-title":"Epidemiology of gastric cancer.","volume":"12","author":"Crew","year":"2006","journal-title":"World J Gastroenterol"},{"key":"R6-9-20210210","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1093\/aje\/154.12.1119","article-title":"Design and serendipity in establishing a large cohort with wide dietary intake distributions: the National Institutes of Health-American Association of Retired Persons Diet and Health Study.","volume":"154","author":"Schatzkin","year":"2001","journal-title":"Am J Epidemiol"},{"key":"R7-9-20210210","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1093\/jn\/116.9.1720","article-title":"Heme, ferritin and vegetable iron absorption in humans from meals denatured of heme iron during the cooking of beef.","volume":"116","author":"Martinez-Torres","year":"1986","journal-title":"J Nutr"},{"key":"R8-9-20210210","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1111\/j.1365-2621.1983.tb09225.x","article-title":"Effects of cooking and chemical treatment on heme and nonheme iron in meat.","volume":"48","author":"Schricker","year":"1983","journal-title":"J Food Sci"},{"key":"R9-9-20210210","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1021\/jf00055a014","article-title":"Evaluation of methods used in meat iron analysis and iron content of raw and cooked meats.","volume":"43","author":"Carpenter","year":"1995","journal-title":"J Agric Food Chem"},{"key":"R10-9-20210210","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1006\/jfca.2002.1080","article-title":"Heme and non-heme iron content of animal products commonly consumed in Thailand.","volume":"15","author":"Kongkachuichai","year":"2002","journal-title":"J food Compost Anal"},{"key":"R11-9-20210210","first-page":"1738","article-title":"Total heme and non-heme iron in raw and cooked meats.","volume":"67","author":"Lombardi-Boccia","year":"2002","journal-title":"Food Chem Toxicol"},{"key":"R12-9-20210210","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/mnfr.200500018","article-title":"Development of a food frequency questionnaire module and databases for compounds in cooked and processed meats.","volume":"49","author":"Sinha","year":"2005","journal-title":"Mol Nutr Food Res"},{"key":"R15-9-20210210","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1023\/A:1008809706062","article-title":"The role of alcohol, tobacco, and dietary factors in upper aerogastric tract cancers: a prospective study of 10,900 Norwegian men.","volume":"9","author":"Kjaerheim","year":"1998","journal-title":"Cancer Causes Control"},{"key":"R16-9-20210210","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/jnci\/djj071","article-title":"Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC).","volume":"98","author":"Gonzalez","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"R17-9-20210210","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/ijc.20616","article-title":"Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China.","volume":"113","author":"Tran","year":"2005","journal-title":"Int J Cancer"},{"key":"R18-9-20210210","doi-asserted-by":"crossref","first-page":"e325","DOI":"10.1371\/journal.pmed.0040325","article-title":"A prospective study of red and processed meat intake in relation to cancer risk.","volume":"4","author":"Cross","year":"2007","journal-title":"PLoS Med"},{"key":"R19-9-20210210","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/(SICI)1097-0215(19970328)71:1<14::AID-IJC4>3.0.CO;2-6","article-title":"Risk of adenocarcinoma of the stomach and esophagus with meat cooking method and doneness preference.","volume":"71","author":"Ward","year":"1997","journal-title":"Int J Cancer"},{"key":"R20-9-20210210","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1002\/ijc.23544","article-title":"Food group intake and risk of subtypes of esophageal and gastric cancer.","volume":"123","author":"Navarro Silvera","year":"2008","journal-title":"Int J Cancer"},{"key":"R21-9-20210210","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/1097-0215(20000715)87:2<289::AID-IJC22>3.0.CO;2-9","article-title":"Food groups and risk of squamous cell esophageal cancer in northern Italy.","volume":"87","author":"Bosetti","year":"2000","journal-title":"Int J Cancer"},{"key":"R22-9-20210210","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/sj.bjc.6601239","article-title":"Food groups and risk of squamous cell carcinoma of the oesophagus: a case-control study in Uruguay.","volume":"89","author":"De Stefani","year":"2003","journal-title":"Br J Cancer"},{"key":"R23-9-20210210","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/00008469-200008000-00005","article-title":"Food groups and oesophageal cancer risk in Vaud, Switzerland.","volume":"9","author":"Levi","year":"2000","journal-title":"Eur J Cancer Prev"},{"key":"R24-9-20210210","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/ijc.21925","article-title":"Processed meat consumption, dietary nitrosamines and stomach cancer risk in a cohort of Swedish women.","volume":"119","author":"Larsson","year":"2006","journal-title":"Int J Cancer"},{"key":"R25-9-20210210","first-page":"627","article-title":"A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption.","volume":"50","author":"Nomura","year":"1990","journal-title":"Cancer Res"},{"key":"R26-9-20210210","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1093\/oxfordjournals.aje.a117743","article-title":"Retinol, antioxidant vitamins, and cancers of the upper digestive tract in a prospective cohort study of postmenopausal women.","volume":"142","author":"Zheng","year":"1995","journal-title":"Am J Epidemiol"},{"key":"R27-9-20210210","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1002\/(SICI)1097-0215(19990315)80:6<852::AID-IJC9>3.0.CO;2-S","article-title":"Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: a follow-up study.","volume":"80","author":"Knekt","year":"1999","journal-title":"Int J Cancer"},{"key":"R28-9-20210210","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/ije\/27.2.173","article-title":"Intakes of selected foods and beverages and the incidence of gastric cancer among the Japanese residents of Hawaii: a prospective study.","volume":"27","author":"Galanis","year":"1998","journal-title":"Int J Epidemiol"},{"key":"R29-9-20210210","first-page":"940","article-title":"Dietary intake of heterocyclic amines and cancers of the esophagus and gastric cardia.","volume":"12","author":"Terry","year":"2003","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R30-9-20210210","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1080\/01635589809514656","article-title":"Dietary nitrosamines, heterocyclic amines, and risk of gastric cancer: a case-control study in Uruguay.","volume":"30","author":"De Stefani","year":"1998","journal-title":"Nutr Cancer"},{"key":"R31-9-20210210","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1207\/S15327914NC402_5","article-title":"Meat consumption and risk of stomach cancer in Uruguay: a case-control study.","volume":"40","author":"De Stefani","year":"2001","journal-title":"Nutr Cancer"},{"key":"R32-9-20210210","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1080\/01635589809514667","article-title":"Feeding of a well-cooked beef diet containing a high heterocyclic amine content enhances colon and stomach carcinogenesis in 1,2-dimethylhydrazine-treated rats.","volume":"30","author":"Pence","year":"1998","journal-title":"Nutr Cancer"},{"key":"R33-9-20210210","first-page":"305","article-title":"A case-control study of element levels and cancer of the upper aerodigestive tract.","volume":"2","author":"Rogers","year":"1993","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R34-9-20210210","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/jnci\/dji042","article-title":"Zinc concentration in esophageal biopsy specimens measured by x-ray fluorescence and esophageal cancer risk.","volume":"97","author":"Abnet","year":"2005","journal-title":"J Natl Cancer Inst"},{"key":"R35-9-20210210","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1093\/annonc\/mdn536","article-title":"Dietary intake of selected micronutrients and gastric cancer risk: an Italian case-control study.","volume":"20","author":"Pelucchi","year":"2009","journal-title":"Ann Oncol"},{"key":"R36-9-20210210","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.mehy.2006.08.025","article-title":"Heme of consumed red meat can act as a catalyst of oxidative damage and could initiate colon, breast and prostate cancers, heart disease and other diseases.","volume":"68","author":"Tappel","year":"2007","journal-title":"Med Hypotheses"},{"key":"R37-9-20210210","first-page":"2358","article-title":"Haem, not protein or inorganic iron, is responsible for endogenous intestinal N-nitrosation arising from red meat.","volume":"63","author":"Cross","year":"2003","journal-title":"Cancer Res"},{"key":"R38-9-20210210","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1093\/carcin\/bgl019","article-title":"Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study.","volume":"27","author":"Jakszyn","year":"2006","journal-title":"Carcinogenesis"},{"key":"R39-9-20210210","first-page":"1055","article-title":"Nutrient intake and risk of subtypes of esophageal and gastric cancer.","volume":"10","author":"Mayne","year":"2001","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R40-9-20210210","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/jnci\/djh265","article-title":"Influence of site classification on cancer incidence rates: an analysis of gastric cardia carcinomas.","volume":"96","author":"Corley","year":"2004","journal-title":"J Natl Cancer Inst"}],"container-title":["American Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ajg2010415.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ajg2010415","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ajg2010415.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/www.ovid.com\/00000434-201103000-00009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T14:26:44Z","timestamp":1786544804000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000434-201103000-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1038\/ajg.2010.415","relation":{},"ISSN":["0002-9270"],"issn-type":[{"value":"0002-9270","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}