{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T23:19:58Z","timestamp":1782515998257,"version":"3.54.5"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1038\/bjc.2011.113","type":"journal-article","created":{"date-parts":[[2011,4,12]],"date-time":"2011-04-12T19:58:31Z","timestamp":1302638311000},"page":"1500-1504","source":"Crossref","is-referenced-by-count":32,"title":["Smoking initiation is followed by the early acquisition of epigenetic change in cervical epithelium: a longitudinal study"],"prefix":"10.1038","volume":"104","author":[{"given":"Y T","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S I","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L S","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P G","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C B J","family":"Woodman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,4,12]]},"reference":[{"key":"BFbjc2011113_CR1","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1002\/ijc.21493","volume":"118","author":"P Appleby","year":"2006","unstructured":"Appleby P, Beral V, Berrington de Gonz\u00e1lez A, Colin D, Franceschi S, Goodill A, Green J, Peto J, Plummer M, Sweetland S, International Collaboration of Epidemiological Studies of Cervical Cancer (2006) Carcinoma of the cervix and tobacco smoking: collaborative reanalysis of individual data on 13\u2009541 women with carcinoma of the cervix and 23\u2009017 women without carcinoma of the cervix from 23 epidemiological studies. Int J Cancer 118: 1481\u20131495","journal-title":"Int J Cancer"},{"key":"BFbjc2011113_CR2","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1164\/rccm.200807-1097OC","volume":"179","author":"A Baccarelli","year":"2009","unstructured":"Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J (2009) Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 179: 572\u2013578","journal-title":"Am J Respir Crit Care Med"},{"key":"BFbjc2011113_CR3","doi-asserted-by":"publisher","first-page":"A55","DOI":"10.1006\/pmed.1998.0382","volume":"27","author":"GI Balch","year":"1998","unstructured":"Balch GI (1998) Exploring perceptions of smoking cessation among high school smokers: input and feedback from focus groups. Prev Med 27: A55\u2013A63","journal-title":"Prev Med"},{"key":"BFbjc2011113_CR4","doi-asserted-by":"publisher","first-page":"6505","DOI":"10.1158\/1078-0432.CCR-05-0625","volume":"11","author":"SA Belinsky","year":"2005","unstructured":"Belinsky SA, Klinge DM, Dekker JD, Smith MW, Bocklage TJ, Gilliland FD, Crowell RE, Karp DD, Stidley CA, Picchi MA (2005) Gene promoter methylation in plasma and sputum increases with lung cancer risk. Clin Cancer Res 11: 6505\u20136511","journal-title":"Clin Cancer Res"},{"key":"BFbjc2011113_CR5","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1158\/0008-5472.CAN-06-2995","volume":"67","author":"V Bollati","year":"2007","unstructured":"Bollati V, Baccarelli A, Hou L, Bonzini M, Fustinoni S, Cavallo D, Byun HM, Jiang J, Marinelli B, Pesatori AC, Bertazzi PA, Yang AS (2007) Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res 67: 876\u2013880","journal-title":"Cancer Res"},{"key":"BFbjc2011113_CR6","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1002\/ijc.21473","volume":"118","author":"R Cirincione","year":"2006","unstructured":"Cirincione R, Lintas C, Conte D, Mariani L, Roz L, Vignola AM, Pastorino U, Sozzi G (2006) Methylation profile in tumor and sputum samples of lung cancer patients detected by spiral computed tomography: a nested case-control study. Int J Cancer 118: 1248\u20131253","journal-title":"Int J Cancer"},{"key":"BFbjc2011113_CR7","first-page":"CD003289","volume":"4","author":"GM Grimshaw","year":"2006","unstructured":"Grimshaw GM, Stanton A (2006) Tobacco cessation interventions for young people. Cochrane Database Syst Rev 4: CD003289","journal-title":"Cochrane Database Syst Rev"},{"key":"BFbjc2011113_CR8","doi-asserted-by":"publisher","first-page":"17046","DOI":"10.1073\/pnas.0806560105","volume":"105","author":"BT Heijmans","year":"2008","unstructured":"Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, Slagboom PE, Lumey LH (2008) Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 105: 17046\u201317049","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFbjc2011113_CR9","first-page":"4525","volume":"55","author":"JG Herman","year":"1995","unstructured":"Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, Sidransky D, Baylin SB (1995) Inactivation of the CDKN2\/CDKN2A\/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55: 4525\u20134530","journal-title":"Cancer Res"},{"key":"BFbjc2011113_CR10","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.jadohealth.2008.10.006","volume":"44","author":"LY Hwang","year":"2009","unstructured":"Hwang LY, Ma Y, Benningfield SM, Clayton L, Hanson EN, Jay J, Jonte J, Godwin de Medina C, Moscicki AB (2009) Factors that influence the rate of epithelial maturation in the cervix in healthy young women. J Adolesc Health 44: 103\u2013110","journal-title":"J Adolesc Health"},{"key":"BFbjc2011113_CR11","first-page":"3743","volume":"63","author":"DH Kim","year":"2003","unstructured":"Kim DH, Kim JS, Ji YI, Shim YM, Kim H, Han J, Park J (2003) Hypermethylation of RASSF1A promoter is associated with the age at starting smoking and a poor prognosis in primary non-small cell lung cancer. Cancer Res 63: 3743\u20133746","journal-title":"Cancer Res"},{"key":"BFbjc2011113_CR12","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1200\/JCO.2004.10.077","volume":"22","author":"H Kim","year":"2004","unstructured":"Kim H, Kwon YM, Kim JS, Lee H, Park JH, Shim YM, Han J, Park J, Kim DH (2004) Tumor-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer. J Clin Oncol 22: 2363\u20132370","journal-title":"J Clin Oncol"},{"key":"BFbjc2011113_CR13","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.addbeh.2008.12.010","volume":"34","author":"M Kleinjan","year":"2009","unstructured":"Kleinjan M, van den Eijnden RJ, Engels RC (2009) Adolescents\u2019 rationalizations to continue smoking: the role of disengagement beliefs and nicotine dependence in smoking cessation. Addict Behav 34: 440\u2013445","journal-title":"Addict Behav"},{"key":"BFbjc2011113_CR14","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/j.ajog.2003.09.036","volume":"190","author":"JS Lea","year":"2004","unstructured":"Lea JS, Coleman R, Kurien A, Schorge JO, Miller DS, Minna JD, Muller CY (2004) Aberrant CDKN2A methylation is a biomarker for tobacco exposure in cervical squamous cell carcinogenesis. Am J Obstet Gynecol 190: 674\u2013679","journal-title":"Am J Obstet Gynecol"},{"key":"BFbjc2011113_CR15","doi-asserted-by":"publisher","first-page":"5900","DOI":"10.1038\/sj.onc.1210400","volume":"26","author":"H Liu","year":"2007","unstructured":"Liu H, Zhou Y, Boggs SE, Belinsky SA, Liu J (2007) Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B. Oncogene 26: 5900\u20135910","journal-title":"Oncogene"},{"key":"BFbjc2011113_CR16","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1002\/ijc.20714","volume":"114","author":"CJ Marsit","year":"2005","unstructured":"Marsit CJ, Kim DH, Liu M, Hinds PW, Wiencke JK, Nelson HH, Kelsey KT (2005) Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence. Int J Cancer 114: 219\u2013223","journal-title":"Int J Cancer"},{"key":"BFbjc2011113_CR17","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1038\/nn.2270","volume":"12","author":"PO McGowan","year":"2009","unstructured":"McGowan PO, Sasaki A, D\u2019Alessio AC, Dymov S, Labont\u00e9 B, Szyf M, Turecki G, Meaney MJ (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12: 342\u2013348","journal-title":"Nat Neurosci"},{"key":"BFbjc2011113_CR18","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1177\/1049732309334056","volume":"19","author":"KL McVea","year":"2009","unstructured":"McVea KL, Miller DL, Creswell JW, McEntarrfer R, Coleman MJ (2009) How adolescents experience smoking cessation. Qual Health Res 19: 580\u2013592","journal-title":"Qual Health Res"},{"key":"BFbjc2011113_CR19","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1038\/nm0795-686","volume":"1","author":"A Merlo","year":"1995","unstructured":"Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D (1995) 5\u2032 CpG island methylation is associated with transcriptional silencing of the tumour suppressor CDKN2A\/CDKN2\/MTS1 in human cancers. Nat Med 1: 686\u2013692","journal-title":"Nat Med"},{"key":"BFbjc2011113_CR20","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1001\/archinternmed.2009.109","volume":"169","author":"SK Myung","year":"2009","unstructured":"Myung SK, McDonnell DD, Kazinets G, Seo HG, Moskowitz JM (2009) Effects of Web- and computer-based smoking cessation programs: meta-analysis of randomized controlled trials. Arch Intern Med 169: 929\u2013937","journal-title":"Arch Intern Med"},{"key":"BFbjc2011113_CR21","first-page":"5954","volume":"60","author":"WA Palmisano","year":"2000","unstructured":"Palmisano WA, Divine KK, Saccomanno G, Gilliland FD, Baylin SB, Herman JG, Belinsky SA (2000) Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res 60: 5954\u20135958","journal-title":"Cancer Res"},{"key":"BFbjc2011113_CR22","doi-asserted-by":"publisher","first-page":"e4488","DOI":"10.1371\/journal.pone.0004488","volume":"4","author":"F Perera","year":"2009","unstructured":"Perera F, Tang WY, Herbstman J, Tang D, Levin L, Miller R, Ho SM (2009) Relation of DNA methylation of 5\u2032-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PLoS One 4: e4488","journal-title":"PLoS One"},{"key":"BFbjc2011113_CR23","doi-asserted-by":"publisher","first-page":"3844","DOI":"10.1158\/0008-5472.CAN-03-2119","volume":"64","author":"LC Pulling","year":"2004","unstructured":"Pulling LC, Vuillemenot BR, Hutt JA, Devereux TR, Belinsky SA (2004) Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens. Cancer Res 64: 3844\u20133848","journal-title":"Cancer Res"},{"key":"BFbjc2011113_CR24","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1002\/ijc.21948","volume":"119","author":"T Soma","year":"2006","unstructured":"Soma T, Kaganoi J, Kawabe A, Kondo K, Imamura M, Shimada Y (2006) Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells. Int J Cancer 119: 1023\u20131027","journal-title":"Int J Cancer"},{"key":"BFbjc2011113_CR25","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1093\/carcin\/bgh038","volume":"25","author":"BR Vuillemenot","year":"2004","unstructured":"Vuillemenot BR, Pulling LC, Palmisano WA, Hutt JA, Belinsky SA (2004) Carcinogen exposure differentially modulates RAR-beta promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis. Carcinogenesis 25: 623\u2013629","journal-title":"Carcinogenesis"},{"key":"BFbjc2011113_CR26","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1289\/ehp.02110555","volume":"110","author":"JK Wiencke","year":"2002","unstructured":"Wiencke JK, Kelsey KT (2002) Teen smoking, field cancerization, and a \u2018critical period\u2019 hypothesis for lung cancer susceptibility. Environ Health Perspect 110: 555\u2013558","journal-title":"Environ Health Perspect"},{"key":"BFbjc2011113_CR27","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1093\/jnci\/91.7.614","volume":"91","author":"JK Wiencke","year":"1990","unstructured":"Wiencke JK, Thurston W, Kelsey KT, Varkonyi A, Wain JC, Mark EJ, Christiani DC (1990) Early age at smoking initiation and tobacco carcinogen DNA damage in the lung. J Natl Cancer Inst 91: 614\u2013619","journal-title":"J Natl Cancer Inst"},{"key":"BFbjc2011113_CR28","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1016\/S0140-6736(00)04956-4","volume":"357","author":"CB Woodman","year":"2001","unstructured":"Woodman CB, Collins S, Winter H, Bailey A, Ellis J, Prior P, Yates M, Rollason TP, Young LS (2001) Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study. Lancet 357: 1831\u20131836","journal-title":"Lancet"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/bjc2011113.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2011113","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2011113.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:00:37Z","timestamp":1684414837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bjc2011113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["BFbjc2011113"],"URL":"https:\/\/doi.org\/10.1038\/bjc.2011.113","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4]]}}}