{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:33:35Z","timestamp":1791333215148,"version":"4.3.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1038\/bjc.2013.604","type":"journal-article","created":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T22:41:54Z","timestamp":1381444914000},"page":"2396-2403","source":"Crossref","is-referenced-by-count":26,"title":["The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome"],"prefix":"10.1038","volume":"109","author":[{"given":"S M","family":"Robinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D A","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D M","family":"Manas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Oakley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S A","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,10,10]]},"reference":[{"issue":"1","key":"BFbjc2013604_CR1","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1097\/00000658-199701000-00006","volume":"225","author":"R Adam","year":"1997","unstructured":"Adam R, Bismuth H, Castaing D, Waechter F, Navarro F, Abascal A, Majno P, Engerran L (1997) Repeat hepatectomy for colorectal liver metastases. Ann Surg 225 (1): 51\u201360, ; Discussion 60\u201362.","journal-title":"Ann Surg"},{"issue":"6","key":"BFbjc2013604_CR2","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1097\/01.sla.0000098112.04758.4e","volume":"238","author":"R Adam","year":"2003","unstructured":"Adam R, Pascal G, Azoulay D, Tanaka K, Castaing D . Bismuth H (2003) Liver resection for colorectal metastases: the third hepatectomy. Ann Surg 238 (6): 871\u2013883, Discussion 883\u2013884.","journal-title":"Ann Surg"},{"issue":"4","key":"BFbjc2013604_CR3","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.jhep.2011.10.023","volume":"56","author":"J Agostini","year":"2012","unstructured":"Agostini J, Benoist S, Seman M, Julie C, Imbeaud S, Letourneur F, Cagnard N, Rougier P, Brouquet A, Zucman-Rossi J, Laurent-Puig P (2012) Identification of molecular pathways involved in oxaliplatin-associated sinusoidal dilatation. J Hepatol 56 (4): 869\u2013876.","journal-title":"J Hepatol"},{"issue":"36","key":"BFbjc2013604_CR4","doi-asserted-by":"publisher","first-page":"9243","DOI":"10.1200\/JCO.2005.07.740","volume":"23","author":"SR Alberts","year":"2005","unstructured":"Alberts SR, Horvath WL, Sternfeld WC, Goldberg RM, Mahoney MR, Dakhil SR, Levitt R, Rowland K, Nair S, Sargent DJ, Donohue JH (2005) Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study. Journal of Clinical Oncology 23 (36): 9243\u20139249.","journal-title":"Journal of Clinical Oncology"},{"key":"BFbjc2013604_CR5","doi-asserted-by":"publisher","first-page":"4343","DOI":"10.1182\/blood-2008-04-149682","volume":"112","author":"L Benimetskaya","year":"2008","unstructured":"Benimetskaya L, Wu S, Voskresenskiy AM, Echart C, Zhou J, Shin J, Iacobelli M, Richardson P, Ayyanar K, Stein CA (2008) Angiogenesis alteration by defibrotide: implications for its mechanism of action in severe hepatic veno-occlusive disease. Blood 112: 4343\u20134352.","journal-title":"Blood"},{"issue":"12","key":"BFbjc2013604_CR6","first-page":"3362","volume":"49","author":"NA Boughattas","year":"1989","unstructured":"Boughattas NA, Levi F, Fournier C, Lemaigre G, Roulon A, Hecquet B, Mathe G, Reinberg A (1989) Circadian rhythm in toxicities and tissue uptake of 1,2-diamminocyclohexane(trans-1)oxalatoplatinum(II) in mice. Cancer Res 49 (12): 3362\u20133368.","journal-title":"Cancer Res"},{"issue":"4","key":"BFbjc2013604_CR7","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.surg.2008.12.002","volume":"145","author":"A Brouquet","year":"2009","unstructured":"Brouquet A, Benoist S, Julie C, Penna C, Beauchet A, Rougier P, Nordlinger B (2009) Risk factors for chemotherapy-associated liver injuries: a multivariate analysis of a group of 146 patients with colorectal metastases. Surgery 145 (4): 362\u2013371.","journal-title":"Surgery"},{"issue":"7","key":"BFbjc2013604_CR8","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1093\/jnci\/88.7.430","volume":"88","author":"S Cao","year":"1996","unstructured":"Cao S, Frank C, Rustum YM (1996) Role of fluoropyrimidine schedule and (6\u2009R,S)leucovorin dose in a preclinical animal model of colorectal carcinoma. J Natl Cancer Inst 88 (7): 430\u2013436.","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"BFbjc2013604_CR9","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.cyto.2007.10.006","volume":"41","author":"M Cheng","year":"2008","unstructured":"Cheng M, Li Y, Wu J, Nie Y, Li L, Liu X, Charoude HN, Chen H (2008) IL-8 induces imbalances between nitric oxide and endothelin-1, and also between plasminogen activator inhibitor-1 and tissue-type plasminogen activator in cultured endothelial cells. Cytokine 41 (1): 9\u201315.","journal-title":"Cytokine"},{"issue":"2","key":"BFbjc2013604_CR10","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1093\/toxsci\/65.2.309","volume":"65","author":"BL Copple","year":"2002","unstructured":"Copple BL, Banes A, Ganey PE, Roth RA (2002) Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure. Toxicol Sci 65 (2): 309\u2013318.","journal-title":"Toxicol Sci"},{"issue":"9","key":"BFbjc2013604_CR11","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1002\/bjs.7194","volume":"97","author":"VE de Meijer","year":"2010","unstructured":"de Meijer VE, Kalish BT, Puder M, Ijzermans JN (2010) Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. Br J Surg 97 (9): 1331\u20131339.","journal-title":"Br J Surg"},{"issue":"6","key":"BFbjc2013604_CR12","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1002\/hep.510290615","volume":"29","author":"LD DeLeve","year":"1999","unstructured":"DeLeve LD, McCuskey RS, Wang X, Hu L, McCuskey MK, Epstein RB, Kanel GC (1999) Characterization of a reproducible rat model of hepatic veno-occlusive disease. Hepatology 29 (6): 1779\u20131791.","journal-title":"Hepatology"},{"issue":"1","key":"BFbjc2013604_CR13","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1055\/s-2002-23204","volume":"22","author":"LD DeLeve","year":"2002","unstructured":"DeLeve LD, Shulman HM, McDonald GB (2002) Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease). Semin Liver Dis 22 (1): 27\u201342.","journal-title":"Semin Liver Dis"},{"issue":"7","key":"BFbjc2013604_CR14","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1038\/sj.bjc.6600185","volume":"86","author":"JL Fischel","year":"2002","unstructured":"Fischel JL, Formento P, Ciccolini J, Rostagno P, Etienne MC, Catalin J, Milano G (2002) Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity. Br J Cancer 86 (7): 1162\u20131168.","journal-title":"Br J Cancer"},{"issue":"2","key":"BFbjc2013604_CR15","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1080\/1024533031000084231","volume":"8","author":"M Kaleelrahman","year":"2003","unstructured":"Kaleelrahman M, Eaton JD, Leeming D, Bowyer K, Taberner D, Chang J, Scarffe JH, Chopra R (2003) Role of plasminogen activator inhibitor-1 (PAI-1) levels in the diagnosis of BMT-associated hepatic veno-occlusive disease and monitoring of subsequent therapy with defibrotide (DF). Hematology 8 (2): 91\u201395.","journal-title":"Hematology"},{"issue":"1","key":"BFbjc2013604_CR16","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/cncr.24710","volume":"116","author":"D Keizman","year":"2010","unstructured":"Keizman D, Maimon N, Ish-Shalom M, Buchbut D, Inbar M, Klein B, Bernheim J, Goldiner I, Leikin-Frenkel A, Konikoff F (2010) An animal model for chemotherapy-associated steatohepatitis and its prevention by the oral administration of fatty acid bile acid conjugate. Cancer 116 (1): 251\u2013255.","journal-title":"Cancer"},{"issue":"6","key":"BFbjc2013604_CR17","doi-asserted-by":"publisher","first-page":"3369","DOI":"10.4049\/jimmunol.170.6.3369","volume":"170","author":"A Li","year":"2003","unstructured":"Li A, Dubey S, Varney ML, Dave BJ, Singh RK (2003) IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 170 (6): 3369\u20133376.","journal-title":"J Immunol"},{"issue":"1","key":"BFbjc2013604_CR18","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s10456-005-5208-4","volume":"8","author":"A Li","year":"2005","unstructured":"Li A, Varney ML, Valasek J, Godfrey M, Dave BJ, Singh RK (2005) Autocrine role of interleukin-8 in induction of endothelial cell proliferation, survival, migration and MMP-2 production and angiogenesis. Angiogenesis 8 (1): 63\u201371.","journal-title":"Angiogenesis"},{"issue":"22","key":"BFbjc2013604_CR19","doi-asserted-by":"publisher","first-page":"3723","DOI":"10.4161\/cc.8.22.10026","volume":"8","author":"I Martins","year":"2009","unstructured":"Martins I, Tesniere A, Kepp O, Michaud M, Schlemmer F, Senovilla L, Seror C, Metivier D, Perfettini JL, Zitvogel L, Kroemer G (2009) Chemotherapy induces ATP release from tumor cells. Cell Cycle 8 (22): 3723\u20133728.","journal-title":"Cell Cycle"},{"issue":"11","key":"BFbjc2013604_CR20","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1111\/j.1477-2574.2011.00365.x","volume":"13","author":"CH Pilgrim","year":"2011","unstructured":"Pilgrim CH, Brettingham-Moore K, Pham A, Murray W, Link E, Smith M, Usatoff V, Evans PM, Banting S, Thomson BN, Michael M, Phillips WA (2011) mRNA gene expression correlates with histologically diagnosed chemotherapy-induced hepatic injury. HPB (Oxford) 13 (11): 811\u2013816.","journal-title":"HPB (Oxford)"},{"issue":"1","key":"BFbjc2013604_CR21","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1097\/SLA.0b013e31815aa2c2","volume":"247","author":"M Rees","year":"2008","unstructured":"Rees M, Tekkis PP, Welsh FK, O'Rourke T, John TG (2008) Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients. Ann Surg 247 (1): 125\u2013135.","journal-title":"Ann Surg"},{"issue":"4","key":"BFbjc2013604_CR22","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1111\/j.1600-0609.1997.tb00985.x","volume":"59","author":"M Remberger","year":"1997","unstructured":"Remberger M, Ringden O (1997) Serum levels of cytokines after bone marrow transplantation: increased IL-8 levels during severe veno-occlusive disease of the liver. Eur J Haematol 59 (4): 254\u2013262.","journal-title":"Eur J Haematol"},{"issue":"2","key":"BFbjc2013604_CR23","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.suronc.2009.10.002","volume":"20","author":"S Robinson","year":"2009","unstructured":"Robinson S, Manas DM, Pedley I, Mann D, White SA (2009) Systemic chemotherapy and its implications for resection of colorectal liver metastasis. Surg Oncol 20 (2): 57\u201372.","journal-title":"Surg Oncol"},{"issue":"2","key":"BFbjc2013604_CR24","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.jhep.2013.04.014","volume":"59","author":"SM Robinson","year":"2013","unstructured":"Robinson SM, Mann J, Vasilaki A, Mathers J, Burt AD, Oakley F, White SA, Mann DA (2013) Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model. J Hepatol 59 (2): 318\u2013326.","journal-title":"J Hepatol"},{"issue":"4","key":"BFbjc2013604_CR25","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1111\/j.1365-2559.2010.03511.x","volume":"56","author":"L Rubbia-Brandt","year":"2010","unstructured":"Rubbia-Brandt L, Lauwers GY, Wang H, Majno PE, Tanabe K, Zhu AX, Brezault C, Soubrane O, Abdalla EK, Vauthey JN, Mentha G, Terris B (2010) Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis. Histopathology 56 (4): 430\u2013439.","journal-title":"Histopathology"},{"issue":"4","key":"BFbjc2013604_CR26","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1158\/1535-7163.MCT-10-1072","volume":"10","author":"L Rubbia-Brandt","year":"2011","unstructured":"Rubbia-Brandt L, Tauzin S, Brezault C, Delucinge-Vivier C, Descombes P, Dousset B, Majno PE, Mentha G, Terris B (2011) Gene expression profiling provides insights into pathways of Oxaliplatin related sinusoidal obstruction syndrome in humans. Mol Cancer Ther 10 (4): 687\u2013696.","journal-title":"Mol Cancer Ther"},{"issue":"6","key":"BFbjc2013604_CR27","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1038\/sj.leu.2402946","volume":"17","author":"R Schots","year":"2003","unstructured":"Schots R, Kaufman L, Van Riet I, Ben Othman T, De Waele M, Van Camp B, Demanet C (2003) Proinflammatory cytokines and their role in the development of major transplant-related complications in the early phase after allogeneic bone marrow transplantation. Leukemia 17 (6): 1150\u20131156.","journal-title":"Leukemia"},{"issue":"3","key":"BFbjc2013604_CR28","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1097\/SLA.0b013e3181c79403","volume":"251","author":"O Soubrane","year":"2010","unstructured":"Soubrane O, Brouquet A, Zalinski S, Terris B, Brezault C, Mallet V, Goldwasser F, Scatton O (2010) Predicting high grade lesions of sinusoidal obstruction syndrome related to oxaliplatin-based chemotherapy for colorectal liver metastases: correlation with post-hepatectomy outcome. Ann Surg 251 (3): 454\u2013460.","journal-title":"Ann Surg"},{"issue":"8910","key":"BFbjc2013604_CR29","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1016\/S0140-6736(94)92529-1","volume":"343","author":"R Stangl","year":"1994","unstructured":"Stangl R, Altendorf-Hofmann A, Charnley RM, Scheele J (1994) Factors influencing the natural history of colorectal liver metastases. Lancet 343 (8910): 1405\u20131410.","journal-title":"Lancet"},{"key":"BFbjc2013604_CR30","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1744-8069-5-9","volume":"5","author":"LE Ta","year":"2009","unstructured":"Ta LE, Low PA, Windebank AJ (2009) Mice with cisplatin and oxaliplatin-induced painful neuropathy develop distinct early responses to thermal stimuli. Mol Pain 5: 9.","journal-title":"Mol Pain"},{"issue":"2","key":"BFbjc2013604_CR31","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1245\/s10434-010-1317-4","volume":"18","author":"D Tamandl","year":"2011","unstructured":"Tamandl D, Klinger M, Eipeldauer S, Herberger B, Kaczirek K, Gruenberger B, Gruenberger T (2011) Sinusoidal obstruction syndrome impairs long-term outcome of colorectal liver metastases treated with resection after neoadjuvant chemotherapy. Ann Surg Oncol 18 (2): 421\u2013430.","journal-title":"Ann Surg Oncol"},{"issue":"5","key":"BFbjc2013604_CR32","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.coi.2008.05.007","volume":"20","author":"A Tesniere","year":"2008","unstructured":"Tesniere A, Apetoh L, Ghiringhelli F, Joza N, Panaretakis T, Kepp O, Schlemmer F, Zitvogel L, Kroemer G (2008) Immunogenic cancer cell death: a key-lock paradigm. Curr Opin Immunol 20 (5): 504\u2013511.","journal-title":"Curr Opin Immunol"},{"issue":"5","key":"BFbjc2013604_CR33","first-page":"600","volume":"50","author":"PV Turner","year":"2011","unstructured":"Turner PV, Brabb T, Pekow C, Vasbinder MA (2011) Administration of substances to laboratory animals: routes of administration and factors to consider. JAALAS 50 (5): 600\u2013613.","journal-title":"JAALAS"},{"issue":"2","key":"BFbjc2013604_CR34","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1002\/hep.510310224","volume":"31","author":"X Wang","year":"2000","unstructured":"Wang X, Kanel GC, DeLeve LD (2000) Support of sinusoidal endothelial cell glutathione prevents hepatic veno-occlusive disease in the rat. Hepatology 31 (2): 428\u2013434.","journal-title":"Hepatology"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/bjc2013604.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2013604","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2013604.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T15:43:23Z","timestamp":1716047003000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bjc2013604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["BFbjc2013604"],"URL":"https:\/\/doi.org\/10.1038\/bjc.2013.604","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}