{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:10:03Z","timestamp":1790298603872,"version":"4.1.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T00:00:00Z","timestamp":1507161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1038\/bjc.2017.338","type":"journal-article","created":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T22:46:25Z","timestamp":1507243585000},"page":"1607-1613","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":87,"title":["The characteristics and outcomes of small bowel adenocarcinoma: a multicentre retrospective observational study"],"prefix":"10.1038","volume":"117","author":[{"given":"Hiroyuki","family":"Sakae","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromitsu","family":"Kanzaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichiro","family":"Nasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Akimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiro","family":"Matsueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Hori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Inaba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Imagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Takatani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Takenaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiyu","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyoshi","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,5]]},"reference":[{"key":"BFbjc2017338_CR1","doi-asserted-by":"publisher","first-page":"2263","DOI":"10.1245\/s10434-007-9428-2","volume":"14","author":"S Agrawal","year":"2007","unstructured":"Agrawal S, McCarron EC, Gibbs JF, Nava HR, Wilding GE, Rajput A (2007) Surgical management and outcome in primary adenocarcinoma of the small bowel. Ann Surg Oncol 14: 2263\u20132269.","journal-title":"Ann Surg Oncol"},{"key":"BFbjc2017338_CR2","doi-asserted-by":"publisher","first-page":"3057","DOI":"10.1038\/bjc.2013.677","volume":"109","author":"T Aparicio","year":"2013","unstructured":"Aparicio T, Svrcek M, Zaanan A, Beohou E, Laforest A, Afchain P, Mitry E, Taieb J, Di Fiore F, Gornet JM, Thirot-Bidault A, Sobhani I, Malka D, Lecomte T, Locher C, Bonnetain F, Laurent-Puig P (2013) Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study. Br J Cancer 109: 3057\u20133066.","journal-title":"Br J Cancer"},{"key":"BFbjc2017338_CR3","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.dld.2013.04.013","volume":"46","author":"T Aparicio","year":"2014","unstructured":"Aparicio T, Zaanan A, Svrcek M, Laurent-Puig P, Carrere N, Manfredi S, Locher C, Afchain P (2014) Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment. Dig Liver Dis 46: 97\u2013104.","journal-title":"Dig Liver Dis"},{"key":"BFbjc2017338_CR4","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1097\/SLA.0b013e31818e4641","volume":"249","author":"KY Bilimoria","year":"2009","unstructured":"Bilimoria KY, Bentrem DJ, Wayne JD, Ko CY, Bennett CL, Talamonti MS (2009) Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 years. Ann Surg 249: 63\u201371.","journal-title":"Ann Surg"},{"key":"BFbjc2017338_CR5","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1477-7819-6-12","volume":"6","author":"K Chaiyasate","year":"2008","unstructured":"Chaiyasate K, Jain AK, Cheung LY, Jacobs MJ, Mittal VK (2008) Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience. World J Surg Oncol 6: 12.","journal-title":"World J Surg Oncol"},{"key":"BFbjc2017338_CR6","doi-asserted-by":"publisher","first-page":"21","DOI":"10.5946\/ce.2016.49.1.21","volume":"49","author":"DY Cheung","year":"2016","unstructured":"Cheung DY, Kim JS, Shim KN, Choi MG Korean Gut Image Study Group (2016) The usefulness of capsule endoscopy for small bowel tumors. Clin Endosc 49: 21\u201325.","journal-title":"Clin Endosc"},{"key":"BFbjc2017338_CR7","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1111\/j.1440-1746.2010.06292.x","volume":"25","author":"DY Cheung","year":"2010","unstructured":"Cheung DY, Lee IS, Chang DK, Kim JO, Cheon JH, Jang BI, Kim YS, Park CH, Lee KJ, Shim KN, Ryu JK, Do JH, Moon JS, Ye BD, Kim KJ, Lim YJ, Choi MG, Chun HJ Korean Gut Images Study Group (2010) Capsule endoscopy in small bowel tumors: a multicenter Korean study. J Gastroenterol Hepatol 25: 1079\u20131086.","journal-title":"J Gastroenterol Hepatol"},{"key":"BFbjc2017338_CR8","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1097\/00000658-200206000-00002","volume":"235","author":"MA Choti","year":"2002","unstructured":"Choti MA, Sitzmann JV, Tiburi MF, Sumetchotimetha W, Rangsin R, Schulick RD, Lillemoe KD, Yeo CJ, Cameron JL (2002) Trends in long-term survival following liver resection for hepatic colorectal metastases. Ann Surg 235: 759\u2013766.","journal-title":"Ann Surg"},{"key":"BFbjc2017338_CR9","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1038\/bjc.1998.523","volume":"78","author":"C Crawley","year":"1998","unstructured":"Crawley C, Ross P, Norman A, Hill A, Cunningham D (1998) The Royal Marsden experience of a small bowel adenocarcinoma treated with protracted venous infusion 5-fluorouracil. Br J Cancer 78: 508\u2013510.","journal-title":"Br J Cancer"},{"key":"BFbjc2017338_CR10","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1016\/S0140-6736(10)60353-4","volume":"375","author":"D Cunningham","year":"2010","unstructured":"Cunningham D, Atkin W, Lenz HJ, Lynch HT, Minsky B, Nordlinger B, Starling N (2010) Colorectal cancer. Lancet 375: 1030\u20131047.","journal-title":"Lancet"},{"key":"BFbjc2017338_CR11","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/cncr.20404","volume":"101","author":"BS Dabaja","year":"2004","unstructured":"Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J (2004) Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients. Cancer 101: 518\u2013526.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR12","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1097\/01.sla.0000138076.72547.b1","volume":"240","author":"FG Fernandez","year":"2004","unstructured":"Fernandez FG, Drebin JA, Linehan DC, Dehdashti F, Siegel BA, Strasberg SM (2004) Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET). Ann Surg 240: 438\u2013447, discussion 447\u2013450.","journal-title":"Ann Surg"},{"key":"BFbjc2017338_CR13","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1016\/j.ejca.2011.10.038","volume":"48","author":"J Faivre","year":"2012","unstructured":"Faivre J, Trama A, De Angelis R, Elferink M, Siesling S, Audisio R, Bosset JF, Cervantes A, Lepage C RARECARE Working Group (2012) Incidence, prevalence and survival of patients with rare epithelial digestive cancers diagnosed in Europe in 1995\u20132002. Eur J Cancer 48: 1417\u20131424.","journal-title":"Eur J Cancer"},{"key":"BFbjc2017338_CR14","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1097\/01. coc.0000214931.01062.01","volume":"29","author":"PN Fishman","year":"2006","unstructured":"Fishman PN, Pond GR, Moore MJ, Oza A, Burkes RL, Siu LL, Feld R, Gallinger S, Greig P, Knox JJ (2006) Natural history and chemotherapy effectiveness for advanced adenocarcinoma of the small bowel: a retrospective review of 113 cases. Am J Clin Oncol 29: 225\u2013231.","journal-title":"Am J Clin Oncol"},{"key":"BFbjc2017338_CR15","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1097\/00000658-199909000-00004","volume":"230","author":"Y Fong","year":"1999","unstructured":"Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH (1999) Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 230: 309\u2013318, discussion 318\u2013321.","journal-title":"Ann Surg"},{"key":"BFbjc2017338_CR16","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.suc.2007.03.011","volume":"87","author":"KR Gardiner","year":"2007","unstructured":"Gardiner KR, Dasari BV (2007) Operative management of small bowel Crohn\u2019s disease. Surg Clin N Am 87: 587\u2013610.","journal-title":"Surg Clin N Am"},{"key":"BFbjc2017338_CR17","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1053\/gast.2000.20228","volume":"119","author":"FM Giardiello","year":"2000","unstructured":"Giardiello FM, Brensinger JD, Tersmette AC, Goodman SN, Petersen GM, Booker SV, Cruz-Correa M, Offerhaus JA (2000) Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 119: 1447\u20131453.","journal-title":"Gastroenterology"},{"key":"BFbjc2017338_CR18","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1136\/gut.21.12.1024","volume":"21","author":"SN Gyde","year":"1980","unstructured":"Gyde SN, Prior P, Macartney JC, Thompson H, Waterhouse JA, Allan RN (1980) Malignancy in Crohn's disease. Gut 21: 1024\u20131029.","journal-title":"Gut"},{"key":"BFbjc2017338_CR19","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.amjsurg.2009.05.037","volume":"199","author":"TR Halfdanarson","year":"2010","unstructured":"Halfdanarson TR, McWilliams RR, Donohue JH, Quevedo JF (2010) A single-institution experience with 491 cases of small bowel adenocarcinoma. Am J Surg 199: 797\u2013803.","journal-title":"Am J Surg"},{"key":"BFbjc2017338_CR20","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1093\/annonc\/mdw064","volume":"27","author":"J Hern\u00e1ndez","year":"2016","unstructured":"Hern\u00e1ndez J, Molins L, Fibla JJ, Heras F, Emb\u00fan R, Rivas JJ Grupo Espa\u00f1ol deMet\u00e1stasis Pulmonares de Carcinoma Colo-Rectal (GECMP-CCR) de la Sociedad Espa\u00f1ola de Neumolog\u00eda y Cirug\u00eda Tor\u00e1cica (SEPAR) (2016) Role of major resection in pulmonary metastasectomy for colorectal cancer in the Spanish prospective multicenter study (GECMP-CCR). Ann Oncol 27: 850\u2013855.","journal-title":"Ann Oncol"},{"key":"BFbjc2017338_CR21","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1093\/jjco\/hyn122","volume":"39","author":"SH Hong","year":"2009","unstructured":"Hong SH, Koh YH, Rho SY, Byun JH, Oh ST, Im KW, Kim EK, Chang SK (2009) Primary adenocarcinoma of the small intestine: presentation, prognostic factors and clinical outcome. Jpn J Clin Oncol 39: 54\u201361.","journal-title":"Jpn J Clin Oncol"},{"key":"BFbjc2017338_CR22","doi-asserted-by":"publisher","first-page":"2693","DOI":"10.1002\/(SICI)1097-0142(19991215)86:12<2693::AID-CNCR14>3.0.CO;2-U","volume":"86","author":"JR Howe","year":"1999","unstructured":"Howe JR, Karnell LH, Menck HR, Scott-Conner C (1999) The American College of Surgeons Commission on Cancer and the American Cancer Society. Adenocarcinoma of the small bowel: review of the National Cancer Data Base, 1985\u20131995. Cancer 86: 2693\u20132706.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR23","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4143\/crt.2015.367","volume":"49","author":"MH Ihn","year":"2017","unstructured":"Ihn MH, Kim DW, Cho S, Oh HK, Jheon S, Kim K, Shin E, Lee HS, Chung JH, Kang SB (2017) Curative resection for metachronous pulmonary metastases from colorectal cancer: analysis of survival rates and prognostic factors. Cancer Res Treat 49: 104\u2013115.","journal-title":"Cancer Res Treat"},{"key":"BFbjc2017338_CR24","first-page":"2121","volume":"55","author":"H Ikeuchi","year":"2008","unstructured":"Ikeuchi H, Nakano H, Uchino M, Nakamura M, Matsuoka H, Fukuda Y, Matsumoto T, Takesue Y, Tomita N (2008) Intestinal cancer in Crohn's disease. Hepatogastroenterology 55: 2121\u20132124.","journal-title":"Hepatogastroenterology"},{"key":"BFbjc2017338_CR25","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1002\/1097-0142(19840101)53:1<23::AID-CNCR2820530106>3.0.CO;2-U","volume":"53","author":"D Jigyasu","year":"1984","unstructured":"Jigyasu D, Bedikian AY, Stroehlein JR (1984) Chemotherapy for primary adenocarcinoma of the small bowel. Cancer 53: 23\u201325.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR26","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1016\/S0022-5223(99)70106-6","volume":"118","author":"K Kobayashi","year":"1999","unstructured":"Kobayashi K, Kawamura M, Ishihara T (1999) Surgical treatment for both pulmonary and hepatic metastases from colorectal cancer. J Thorac Cardiovasc Surg 118: 1090\u20131096.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BFbjc2017338_CR27","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1186\/1471-2407-11-205","volume":"11","author":"DH Koo","year":"2011","unstructured":"Koo DH, Yun SC, Hong YS, Ryu MH, Lee JL, Chang HM, Ryoo BY, Kang YK, Kim TW (2011) Systemic chemotherapy for treatment of advanced small bowel adenocarcinoma with prognostic factor analysis: retrospective study. BMC Cancer 11: 205.","journal-title":"BMC Cancer"},{"key":"BFbjc2017338_CR28","first-page":"44","volume":"78","author":"BI Korelitz","year":"1983","unstructured":"Korelitz BI (1983) Carcinoma of the intestinal tract in Crohn's disease: results of a survey conducted by the National Foundation for Ileitis and colitis. Am J Gastroenterol 78: 44\u201346.","journal-title":"Am J Gastroenterol"},{"key":"BFbjc2017338_CR29","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1186\/s12885-016-2276-3","volume":"16","author":"G Li","year":"2016","unstructured":"Li G, Wang Z, Xu J, Wu H, Cai S, He Y (2016) The prognostic value of lactate dehydrogenase levels in colorectal cancer: a meta-analysis. BMC Cancer 16: 249.","journal-title":"BMC Cancer"},{"key":"BFbjc2017338_CR30","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1159\/000089678","volume":"69","author":"C Locher","year":"2005","unstructured":"Locher C, Malka D, Boige V, Lebray P, Elias D, Lasser P, Ducreux M (2005) Combination chemotherapy in advanced small bowel adenocarcinoma. Oncology 69: 290\u2013294.","journal-title":"Oncology"},{"key":"BFbjc2017338_CR31","doi-asserted-by":"publisher","first-page":"820","DOI":"10.3892\/mco.2013.150","volume":"1","author":"T Mizushima","year":"2013","unstructured":"Mizushima T, Tamagawa H, Mishima H, Ikeda K, Fujita S, Akamatsu H, Ikenaga M, Onishi T, Fukunaga M, Fukuzaki T, Hasegawa J, Takemasa I, Ikeda M, Yamamoto H, Sekimoto M, Nezu R, Doki Y, Mori M (2013) The effects of chemotherapy on primary small bowel cancer: a retrospective multicenter observational study in Japan. Mol Clin Oncol 1: 820\u2013824.","journal-title":"Mol Clin Oncol"},{"key":"BFbjc2017338_CR32","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1002\/(SICI)1097-0142(19980915)83:6<1086::AID-CNCR6>3.0.CO;2-6","volume":"83","author":"S Murata","year":"1998","unstructured":"Murata S, Moriya Y, Akasu T, Fujita S, Sugihara K (1998) Resection of both hepatic and pulmonary metastases in patients with colorectal carcinoma. Cancer 83: 1086\u20131093.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR33","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1007\/s11605-009-0960-1","volume":"13","author":"H Neeff","year":"2009","unstructured":"Neeff H, H\u00f6rth W, Makowiec F, Fischer E, Imdahl A, Hopt UT, Passlick B (2009) Outcome after resection of hepatic and pulmonary metastases of colorectal cancer. J Gastrointest Surg 13: 1813\u20131820.","journal-title":"J Gastrointest Surg"},{"key":"BFbjc2017338_CR34","first-page":"243","volume":"7","author":"AI Neugut","year":"1998","unstructured":"Neugut AI, Jacobson JS, Suh S, Mukherjee R, Arber N (1998) The epidemiology of cancer of the small bowel. Cancer Epidemiol Biomarkers Prev 7: 243\u2013251.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"BFbjc2017338_CR35","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/0002-9610(84)90036-9","volume":"147","author":"K Ouriel","year":"1984","unstructured":"Ouriel K, Adams JT (1984) Adenocarcinoma of the small intestine. Am J Surg 147: 66\u201371.","journal-title":"Am J Surg"},{"key":"BFbjc2017338_CR36","first-page":"90","volume":"3","author":"MJ Overman","year":"2009","unstructured":"Overman MJ (2009) Recent advances in the management of adenocarcinoma of the small intestine. Gastrointest Cancer Res 3: 90\u201396.","journal-title":"Gastrointest Cancer Res"},{"key":"BFbjc2017338_CR37","doi-asserted-by":"publisher","first-page":"5374","DOI":"10.1002\/cncr.25324","volume":"116","author":"MJ Overman","year":"2010","unstructured":"Overman MJ, Hu CY, Wolff RA, Chang GJ (2010) Prognostic value of lymph node evaluation in small bowel adenocarcinoma: analysis of the surveillance epidemiology, and end results database. Cancer 116: 5374\u20135382.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR38","doi-asserted-by":"publisher","first-page":"2038","DOI":"10.1002\/cncr.23822","volume":"113","author":"MJ Overman","year":"2008","unstructured":"Overman MJ, Kopetz S, Wen S, Hoff PM, Fogelman D, Morris J, Abbruzzese JL, Ajani JA, Wolff RA (2008) Chemotherapy with 5-fluorouracil and a platinum compound improves outcomes in metastatic small bowel adenocarcinoma. Cancer 113: 2038\u20132045.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR39","doi-asserted-by":"publisher","first-page":"9437","DOI":"10.3748\/wjg.v21.i31.9437","volume":"21","author":"FC Paquissi","year":"2015","unstructured":"Paquissi FC, Lima AH, Lopes Mde F, Diaz FV (2015) Adenocarcinoma of the third and fourth portions of the duodenum: the capsule endoscopy value. World J Gastroenterol 21: 9437\u20139441.","journal-title":"World J Gastroenterol"},{"key":"BFbjc2017338_CR40","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/S0140-6736(83)91754-3","volume":"1","author":"CM Swinson","year":"1983","unstructured":"Swinson CM, Slavin G, Coles EC, Booth CC (1983) Coeliac disease and malignancy. Lancet 1: 111\u2013115.","journal-title":"Lancet"},{"key":"BFbjc2017338_CR41","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.annepidem.2008.10.004","volume":"19","author":"D Schottenfeld","year":"2009","unstructured":"Schottenfeld D, Beebe-Dimmer JL, Vigneau FD (2009) The epidemiology and pathogenesis of neoplasia in the small intestine. Ann Epidemiol 19: 58\u201369.","journal-title":"Ann Epidemiol"},{"key":"BFbjc2017338_CR42","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s10147-012-0382-z","volume":"18","author":"T Takahashi","year":"2013","unstructured":"Takahashi T, Shibata Y, Tojima Y, Tsuboi K, Sakamoto E, Kunieda K, Matsuoka H, Suzumura K, Sato M, Naganuma T, Sakamoto J, Morita S, Kondo K (2013) Multicenter phase II study of modified FOLFOX6 as neoadjuvant chemotherapy for patients with unresectable liver-only metastases from colorectal cancer in Japan: ROOF study. Int J Clin Oncol 18: 335\u2013342.","journal-title":"Int J Clin Oncol"},{"key":"BFbjc2017338_CR43","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.ejso.2015.11.007","volume":"42","author":"M Takatsuki","year":"2016","unstructured":"Takatsuki M, Tokunaga S, Uchida S, Sakoda M, Shirabe K, Beppu T, Emi Y, Oki E, Ueno S, Eguchi S, Akagi Y, Ogata Y, Baba H, Natsugoe S, Maehara Y Kyushu Study Group of Clinical Cancer (KSCC) (2016) Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: a multicenter study. Eur J Surg Oncol 42: 184\u2013189.","journal-title":"Eur J Surg Oncol"},{"key":"BFbjc2017338_CR44","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1001\/archsurg.137.5.564","volume":"137","author":"MS Talamonti","year":"2002","unstructured":"Talamonti MS, Goetz LH, Rao S, Joehl RJ (2002) Primary cancers of the small bowel: analysis of prognostic factors and results of surgical management. Arch Surg 137: 564\u2013570, discussion 570\u2013571.","journal-title":"Arch Surg"},{"key":"BFbjc2017338_CR45","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1634\/theoncologist.2012-0079","volume":"17","author":"T Tsushima","year":"2012","unstructured":"Tsushima T, Taguri M, Honma Y, Takahashi H, Ueda S, Nishina T, Kawai H, Kato S, Suenaga M, Tamura F, Morita S, Boku N (2012) Multicenter retrospective study of 132 patients with unresectable small bowel adenocarcinoma treated with chemotherapy. Oncologist 17: 1163\u20131170.","journal-title":"Oncologist"},{"key":"BFbjc2017338_CR46","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s00268-005-7898-6","volume":"30","author":"TJ Wu","year":"2006","unstructured":"Wu TJ, Yeh CN, Chao TC, Jan YY, Chen MF (2006) Prognostic factors of primary small bowel adenocarcinoma: univariatef and multivariate analysis. World J Surg 30: 391\u2013398,, discussion 399.","journal-title":"World J Surg"},{"key":"BFbjc2017338_CR47","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1245\/s10434-006-9100-2","volume":"13","author":"S Yedibela","year":"2006","unstructured":"Yedibela S, Klein P, Feuchter K, Hoffmann M, Meyer T, Papadopoulos T, G\u00f6hl J, Hohenberger W (2006) Surgical management of pulmonary metastases from colorectal cancer in 153 patients. Ann Surg Oncol 13: 1538\u20131544.","journal-title":"Ann Surg Oncol"},{"key":"BFbjc2017338_CR48","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1093\/annonc\/mdq038","volume":"21","author":"A Zaanan","year":"2010","unstructured":"Zaanan A, Costes L, Gauthier M, Malka D, Locher C, Mitry E, Tougeron D, Lecomte T, Gornet JM, Sobhani I, Moulin V, Afchain P, Ta\u00efeb J, Bonnetain F, Aparicio T (2010) Chemotherapy of advanced small-bowel adenocarcinoma: a multicenter AGEO study. Ann Oncol 21: 1786\u20131793.","journal-title":"Ann Oncol"},{"key":"BFbjc2017338_CR49","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1002\/cncr.25614","volume":"117","author":"A Zaanan","year":"2011","unstructured":"Zaanan A, Gauthier M, Malka D, Locher C, Gornet JM, Thirot-Bidault A, Tougeron D, Ta\u00efeb J, Bonnetain F, Aparicio T Association des Gastro Ent\u00e9rologues Oncologues (2011) Second-line chemotherapy with fluorouracil, leucovorin, and irinotecan (FOLFIRI regimen) in patients with advanced small bowel adenocarcinoma after failure of first-line platinum-based chemotherapy: a multicenter AGEO study. Cancer 117: 1422\u20131428.","journal-title":"Cancer"},{"key":"BFbjc2017338_CR50","doi-asserted-by":"publisher","first-page":"9800","DOI":"10.1038\/srep09800","volume":"5","author":"J Zhang","year":"2015","unstructured":"Zhang J, Yao YH, Li BG, Yang Q, Zhang PY, Wang HT (2015) Prognostic value of pretreatment serum lactate dehydrogenase level in patients with solid tumors: a systematic review and meta-analysis. Sci Rep 5: 9800.","journal-title":"Sci Rep"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/bjc2017338.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2017338","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/bjc.2017.338","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2017338.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:39:41Z","timestamp":1684417181000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bjc2017338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,5]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["BFbjc2017338"],"URL":"https:\/\/doi.org\/10.1038\/bjc.2017.338","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,5]]},"assertion":[{"value":"24 April 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2017","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}