{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:37:11Z","timestamp":1790163431953,"version":"4.1.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T00:00:00Z","timestamp":1515456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"},{"start":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T00:00:00Z","timestamp":1515456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[2018,2,20]]},"DOI":"10.1038\/bjc.2017.449","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T21:01:40Z","timestamp":1515531700000},"page":"611-615","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Aspirin use and ovarian cancer mortality in a Danish nationwide cohort study"],"prefix":"10.1038","volume":"118","author":[{"given":"Freija","family":"Verdoodt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne K","family":"Kjaer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Dehlendorff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Friis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,1,9]]},"reference":[{"key":"BFbjc2017449_CR1","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/S0140-6736(14)62038-9","volume":"385","author":"C Allemani","year":"2015","unstructured":"Allemani C, Weir HK, Carreira H, Harewood R, Spika D, Wang XS, Bannon F, Ahn JV, Johnson CJ, Bonaventure A, Marcos-Gragera R, Stiller C, Azevedo e Silva G, Chen WQ, Ogunbiyi OJ, Rachet B, Soeberg MJ, You H, Matsuda T, Bielska-Lasota M, Storm H, Tucker TC, Coleman MP (2015) Global surveillance of cancer survival 1995\u20132009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2). Lancet 385: 977\u20131010.","journal-title":"Lancet"},{"key":"BFbjc2017449_CR2","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.ejogrb.2016.09.005","volume":"207","author":"D Bar","year":"2016","unstructured":"Bar D, Lavie O, Stein N, Feferkorn I, Shai A (2016) The effect of metabolic comorbidities and commonly used drugs on the prognosis of patients with ovarian cancer. Eur J Obstet Gynecol Reprod Biol 207: 227\u2013231.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"10","key":"BFbjc2017449_CR3","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1182\/blood-2017-02-769893","volume":"30","author":"MS Cho","year":"2017","unstructured":"Cho MS, Noh K, Haemmerle M, Li D, Park H, Hu Q, Hisamatsu T, Mitamura T, Mak SLC, Kunapuli S, Ma Q, Sood AK, Afshar-Kharghan V (2017) Role of ADP receptors on platelets in the growth of ovarian cancer. Blood 30 (10): 1235\u20131242.","journal-title":"Blood"},{"key":"BFbjc2017449_CR4","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1093\/jnci\/djt211","volume":"105","author":"J Chubak","year":"2013","unstructured":"Chubak J, Boudreau DM, Wirtz HS, McKnight B, Weiss NS (2013) Threats to validity of nonrandomized studies of postdiagnosis exposures on cancer recurrence and survival. J Natl Cancer Inst 105: 1456\u20131462.","journal-title":"J Natl Cancer Inst"},{"key":"BFbjc2017449_CR5","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1186\/s12885-015-1634-x","volume":"15","author":"NM Cooke","year":"2015","unstructured":"Cooke NM, Spillane CD, Sheils O, O'Leary J, Kenny D (2015) Aspirin and P2Y12 inhibition attenuate platelet-induced ovarian cancer cell invasion. BMC Cancer 15: 627.","journal-title":"BMC Cancer"},{"key":"BFbjc2017449_CR6","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s11888-016-0306-9","volume":"12","author":"C Coyle","year":"2016","unstructured":"Coyle C, Cafferty FH, Langley RE (2016) Aspirin and colorectal cancer prevention and treatment: is it for everyone? Curr Colorectal Cancer Rep 12: 27\u201334.","journal-title":"Curr Colorectal Cancer Rep"},{"key":"BFbjc2017449_CR7","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1038\/bjc.2017.68","volume":"116","author":"SC Dixon","year":"2017","unstructured":"Dixon SC, Nagle CM, Wentzensen N, Trabert B, Beeghly-Fadiel A, Schildkraut JM, Moysich KB, deFazio A, Risch HA, Rossing MA, Doherty JA, Wicklund KG, Goodman MT, Modugno F, Ness RB, Edwards RP, Jensen A, Kjaer SK, Hogdall E, Berchuck A, Cramer DW, Terry KL, Poole EM, Bandera EV, Paddock LE, Anton-Culver H, Ziogas A, Menon U, Gayther SA, Ramus SJ, Gentry-Maharaj A, Pearce CL, Wu AH, Pike MC, Webb PM (2017) Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium. Br J Cancer 116: 1223\u20131228.","journal-title":"Br J Cancer"},{"key":"BFbjc2017449_CR8","doi-asserted-by":"publisher","first-page":"e0152402","DOI":"10.1371\/journal.pone.0152402","volume":"11","author":"PC Elwood","year":"2016","unstructured":"Elwood PC, Morgan G, Pickering JE, Galante J, Weightman AL, Morris D, Kelson M, Dolwani S (2016) Aspirin in the treatment of cancer: reductions in metastatic spread and in mortality: a systematic review and meta-analyses of published studies. PLoS One 11: e0152402.","journal-title":"PLoS One"},{"key":"BFbjc2017449_CR9","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","volume":"94","author":"JP Fine","year":"1999","unstructured":"Fine JP, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94: 496\u2013509.","journal-title":"J Am Stat Assoc"},{"key":"BFbjc2017449_CR10","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1158\/1055-9965.EPI-09-0975","volume":"19","author":"MA Gates","year":"2010","unstructured":"Gates MA, Tworoger SS, Eliassen AH, Missmer SA, Hankinson SE (2010) Analgesic use and sex steroid hormone concentrations in postmenopausal women. Cancer Epidemiol Biomarkers Prev 19: 1033\u20131041.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"BFbjc2017449_CR11","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1158\/1055-9965.EPI-07-2739","volume":"17","author":"AG Hudson","year":"2008","unstructured":"Hudson AG, Gierach GL, Modugno F, Simpson J, Wilson JW, Evans RW, Vogel VG, Weissfeld JL (2008) Nonsteroidal anti-inflammatory drug use and serum total estradiol in postmenopausal women. Cancer Epidemiol Biomarkers Prev 17: 680\u2013687.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"BFbjc2017449_CR12","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1158\/1055-9965.EPI-15-0508","volume":"24","author":"AN Minlikeeva","year":"2015","unstructured":"Minlikeeva AN, Freudenheim JL, Lo-Ciganic WH, Eng KH, Friel G, Diergaarde B, Modugno F, Cannioto R, Gower E, Szender JB, Grzankowski K, Odunsi K, Ness RB, Moysich KB (2015) Use of common analgesics is not associated with ovarian cancer survival. Cancer Epidemiol Biomarkers Prev 24: 1291\u20131294.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"BFbjc2017449_CR13","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.canep.2014.12.010","volume":"39","author":"CM Nagle","year":"2015","unstructured":"Nagle CM, Ibiebele TI, DeFazio A, Protani MM, Webb PM (2015) Aspirin, nonaspirin nonsteroidal anti-inflammatory drugs, acetaminophen and ovarian cancer survival. Cancer Epidemiol 39: 196\u2013199.","journal-title":"Cancer Epidemiol"},{"key":"BFbjc2017449_CR14","doi-asserted-by":"crossref","unstructured":"R Foundation for Statistical Computing (2015) R: A Language and Environment for Statistical Computing [Online] R Core Team: Vienna, Austria. Available at: https:\/\/www.r-project.org\/ . Accessed on 1 January 2017.","DOI":"10.1201\/9780203758212-1"},{"key":"BFbjc2017449_CR15","doi-asserted-by":"publisher","first-page":"155","DOI":"10.2147\/CLEP.S59156","volume":"6","author":"M Schmidt","year":"2014","unstructured":"Schmidt M, Hallas J, Friis S (2014) Potential of prescription registries to capture individual-level use of aspirin and other nonsteroidal anti-inflammatory drugs in Denmark: trends in utilization 1999\u20132012. Clin Epidemiol 6: 155\u2013168.","journal-title":"Clin Epidemiol"},{"key":"BFbjc2017449_CR16","unstructured":"Therneau T (2015) A Package for Survival Analysis in S, version 2.38 [Online]. Available at: http:\/\/CRAN.R-project.org\/package=survival . Accessed on 1 January 2017."},{"key":"BFbjc2017449_CR17","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/nrclinonc.2011.199","volume":"9","author":"MJ Thun","year":"2012","unstructured":"Thun MJ, Jacobs EJ, Patrono C (2012) The role of aspirin in cancer prevention. Nat Rev Clin Oncol 9: 259\u2013267.","journal-title":"Nat Rev Clin Oncol"},{"key":"BFbjc2017449_CR18","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1177\/1403494811399956","volume":"39","author":"LC Thygesen","year":"2011","unstructured":"Thygesen LC, Daasnes C, Thaulow I, Br\u00f8nnum-Hansen H (2011) Introduction to Danish (nationwide) registers on health and social issues: structure, access, legislation, and archiving. Scand J Public Health 39: 12\u201316.","journal-title":"Scand J Public Health"},{"key":"BFbjc2017449_CR19","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1053\/j.seminoncol.2015.09.010","volume":"43","author":"A Umar","year":"2016","unstructured":"Umar A, Steele VE, Menter DG, Hawk ET (2016) Mechanisms of nonsteroidal anti-inflammatory drugs in cancer prevention. Semin Oncol 43: 65\u201377.","journal-title":"Semin Oncol"},{"key":"BFbjc2017449_CR20","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1002\/ijc.30738","volume":"141","author":"F Verdoodt","year":"2017","unstructured":"Verdoodt F, Kjaer Hansen M, Kjaer SK, Pottegard A, Friis S, Dehlendorff C (2017a) Statin use and mortality among ovarian cancer patients: a population-based cohort study. Int J Cancer 141: 279\u2013286.","journal-title":"Int J Cancer"},{"key":"BFbjc2017449_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.maturitas.2017.03.001","volume":"100","author":"F Verdoodt","year":"2017","unstructured":"Verdoodt F, Kjaer SK, Friis S (2017b) Influence of aspirin and non-aspirin NSAID use on ovarian and endometrial cancer: summary of epidemiologic evidence of cancer risk and prognosis. Maturitas 100: 1\u20137.","journal-title":"Maturitas"},{"key":"BFbjc2017449_CR22","doi-asserted-by":"publisher","first-page":"573","DOI":"10.7326\/0003-4819-147-8-200710160-00010","volume":"147","author":"E von Elm","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP (2007) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med 147: 573\u2013577.","journal-title":"Ann Intern Med"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/bjc2017449.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2017449","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/bjc.2017.449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/bjc2017449.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T11:13:40Z","timestamp":1719746020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bjc2017449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,9]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,2,20]]}},"alternative-id":["BFbjc2017449"],"URL":"https:\/\/doi.org\/10.1038\/bjc.2017.449","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,9]]},"assertion":[{"value":"8 August 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2018","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}