{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T06:56:03Z","timestamp":1760079363676},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"S2","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2008,6,1]]},"DOI":"10.1038\/bmt.2008.64","type":"journal-article","created":{"date-parts":[[2008,6,11]],"date-time":"2008-06-11T04:09:50Z","timestamp":1213157390000},"page":"S96-S99","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Haematopoietic SCT in autoimmune diseases in children: rationale and new perspectives"],"prefix":"10.1038","volume":"41","author":[{"given":"M","family":"Rabusin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Andolina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Maximova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the EBMT Paediatric and Autoimmune Diseases Working Parties","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,6,11]]},"reference":[{"key":"BFbmt200864_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1006\/clin.1997.4412","volume":"84","author":"DL Jacobson","year":"1997","unstructured":"Jacobson DL, Gange SJ, Rose NR, Graham NM . Epidemiology and estimates population burden of selected autoimmune diseases in United States. Clin Immunol Immunopathol 1997; 84: 223\u2013243.","journal-title":"Clin Immunol Immunopathol"},{"key":"BFbmt200864_CR2","doi-asserted-by":"publisher","first-page":"1380","DOI":"10.1126\/science.1972595","volume":"248","author":"AA Sinha","year":"1990","unstructured":"Sinha AA, Lopez MT, Mc Devitt HO . Autoimmune diseases: the failure of self tolerance. Science 1990; 248: 1380\u20131385.","journal-title":"Science"},{"key":"BFbmt200864_CR3","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1146\/annurev.med.51.1.115","volume":"51","author":"AM Marmont","year":"2000","unstructured":"Marmont AM . New horizons in the treatment of autoimmune diseases: immunoablation and stem cell transplantation. Ann Rev Med 2000; 51: 114\u2013134.","journal-title":"Ann Rev Med"},{"key":"BFbmt200864_CR4","first-page":"324","volume-title":"The Autoimmune Diseases","author":"KL Lafferty","year":"1998","unstructured":"Lafferty KL, Gazda LS (eds). Costimulation and the regulation of autoimmunity. The Autoimmune Diseases. Academic: San Diego, 1998, pp 324\u2013330."},{"key":"BFbmt200864_CR5","doi-asserted-by":"publisher","first-page":"10090","DOI":"10.1073\/pnas.86.24.10090","volume":"86","author":"DW van Bekkum","year":"1989","unstructured":"van Bekkum DW, Bohre EP, Houben PF, Knaan-Shanzer S . Regression of adjuvant-induced arthritis in rats following bone marrow transplantation. Proc Soc Natl Sci USA 1989; 86: 10090\u201310094.","journal-title":"Proc Soc Natl Sci USA"},{"key":"BFbmt200864_CR6","first-page":"833","volume":"8","author":"S Knaan-Shanzer","year":"1991","unstructured":"Knaan-Shanzer S, Houben P, Kinwel-Bohre EP, van Bekkum DW . Remission induction of adjuvant arthritis in rats by total body irradiation and autologous bone marrow transplantation. Bone Marrow Transplant 1991; 8: 833\u2013838.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200864_CR7","first-page":"1183","volume":"11","author":"DW van Bekkum","year":"1993","unstructured":"van Bekkum DW . BMT in experimental autoimmune diseases. Bone Marrow Transplant 1993; 11: 1183\u20131187.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200864_CR8","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/j.1365-2141.2004.05298.x","volume":"128","author":"RE Hough","year":"2005","unstructured":"Hough RE, Snowden JA, Wulffraat N . Haemopoietic stem cell transplantation in autoimmune diseases: a European perspective. Br J Haematol 2005; 128: 432\u2013459.","journal-title":"Br J Haematol"},{"key":"BFbmt200864_CR9","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1002\/1529-0131(199803)41:3<453::AID-ART11>3.0.CO;2-#","volume":"41","author":"JA Snowden","year":"1998","unstructured":"Snowden JA, Kearney P, Kearney A, Cooley HM, Grigg A, Jacobs P et al. Long-term outcome of autoimmune disease following allogeneic bone marrow transplantation. Arthritis Rheum 1998; 41: 453\u2013459.","journal-title":"Arthritis Rheum"},{"key":"BFbmt200864_CR10","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/S0016-5085(98)70525-6","volume":"114","author":"SO Lopes Cubero","year":"1998","unstructured":"Lopes Cubero SO, Sullivan KM, McDonald GB . Course of Crohn's disease after allogeneic bone marrow transplantation. Gastroenterology 1998; 114: 433\u2013440.","journal-title":"Gastroenterology"},{"key":"BFbmt200864_CR11","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1038\/sj.bmt.1701823","volume":"23","author":"AM Marmont","year":"1999","unstructured":"Marmont AM . Immune ablation and stem cell transplantation for severe Evans syndrome and refractory thrombocytopenic purpura. Bone Marrow transplant 1999; 23: 1215\u20131216.","journal-title":"Bone Marrow transplant"},{"key":"BFbmt200864_CR12","first-page":"71","volume":"85","author":"AM Marmont","year":"2000","unstructured":"Marmont AM . Immunoablation followed or not by hematopoietic stem cells as an intensive therapy for severe autoimmune diseases. New perspectives, new problems. Haematologica 2000; 85: 71\u201380.","journal-title":"Haematologica"},{"key":"BFbmt200864_CR13","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1136\/ard.2003.017798","volume":"63","author":"IM de Kleer","year":"2004","unstructured":"de Kleer IM, Brinkman DMC, Ferster A, Abinun M, Quartier P, van der J et al. Autologous stem cell transplantation for refractory juvenile idiopathic arthritis: analysis of clinical effects, mortality, and transplant related morbidity. Ann Rheum Dis 2004; 63: 1318\u20131326.","journal-title":"Ann Rheum Dis"},{"key":"BFbmt200864_CR14","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1136\/ard.2003.011205","volume":"63","author":"D Farge","year":"2004","unstructured":"Farge D, Passweg J, van Laar JM, Marjanovic Z, Besenthal C, Finke J et al. Autologous stem cell transplantation in the treatment of systemic sclerosis: report from the EBMT\/EULAR Registry. Ann Rheum Dis 2004; 63: 974\u2013981.","journal-title":"Ann Rheum Dis"},{"key":"BFbmt200864_CR15","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1191\/0961203304lu525oa","volume":"13","author":"D Jayne","year":"2004","unstructured":"Jayne D, Passweg J, Marmont A, Farge D, Zhao X, Arnold D et al. Autologous stem cell transplantation for systemic lupus erythematosus. Lupus 2004; 13: 168\u2013176.","journal-title":"Lupus"},{"key":"BFbmt200864_CR16","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1111\/j.1365-2141.2004.04978.x","volume":"125","author":"J Passweg","year":"2004","unstructured":"Passweg J, Rabusin M, Musso M, Beguin Y, Cesaro S, Ehninger G et al. Haematopoietic stem cell transplantation for refractory autoimmune cytopenia. Br J Haematol 2004; 125: 749\u2013755.","journal-title":"Br J Haematol"},{"key":"BFbmt200864_CR17","first-page":"81","volume":"85","author":"M Rabusin","year":"2000","unstructured":"Rabusin M, Andolina M, Maximova N, Lepore L, Parco S, Tuveri G et al. Immunoablation followed by autologous hematopoietic stem cell infusion for the treatment of severe autoimmune disease. Haematologica 2000; 85: 81\u201385.","journal-title":"Haematologica"},{"key":"BFbmt200864_CR18","first-page":"308","volume":"22","author":"BA Gare","year":"1995","unstructured":"Gare BA, Fasht A . The natural history of juvenile chronic arthritis: a population based cohort study. II. Outcome. J Rheumatol 1995; 22: 308\u2013319.","journal-title":"J Rheumatol"},{"key":"BFbmt200864_CR19","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1093\/rheumatology\/38.8.739","volume":"38","author":"RE Petty","year":"1999","unstructured":"Petty RE . Prognosis in children with rheumatic disease; justification for consideration of new therapies. Rheumatology (Oxford) 1999; 38: 739\u2013742.","journal-title":"Rheumatology (Oxford)"},{"key":"BFbmt200864_CR20","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1002\/art.10885","volume":"48","author":"P Quartier","year":"2003","unstructured":"Quartier P, Taupin P, Bourdeau F, Lemelle I, Pillet P, Bost M et al. Efficacy of etanercept for the treatment of JIA according to the onset type. Arthritis Rheum 2003; 48: 1093\u20131101.","journal-title":"Arthritis Rheum"},{"key":"BFbmt200864_CR21","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1002\/art.20944","volume":"52","author":"S Yokota","year":"2005","unstructured":"Yokota S, Miyamae T, Imagawa T, Iwata N, Katakura S, Mori M et al. Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2005; 52: 818\u2013825.","journal-title":"Arthritis Rheum"},{"key":"BFbmt200864_CR22","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1097\/00005792-199905000-00003","volume":"78","author":"R Cervera","year":"1999","unstructured":"Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P et al. Morbidity and mortality in SLE during a 5-year period: a multicenter prospective study of 1000 patients. Medicine 1999; 78: 167\u2013175.","journal-title":"Medicine"},{"key":"BFbmt200864_CR23","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1111\/j.1365-2249.2005.02795.x","volume":"140","author":"F Goldblatt","year":"2005","unstructured":"Goldblatt F, Isenberg DA . New therapies for systemic lupus erythematosus. Clin Exp Immunol 2005; 140: 205\u2013212.","journal-title":"Clin Exp Immunol"},{"key":"BFbmt200864_CR24","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/j.amjmed.2005.11.034","volume":"119","author":"A Doria","year":"2006","unstructured":"Doria A, Iaccarino L, Ghirardello A, Zampieri S, Arienti S, Sarzi-Puttini P et al. Long-term prognosis and causes of death in systemic lupus erythematosus. Am J Med 2006; 119: 700\u2013706.","journal-title":"Am J Med"},{"key":"BFbmt200864_CR25","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1007\/s10067-004-1065-6","volume":"24","author":"J Chen","year":"2005","unstructured":"Chen J, Wang Y, Kunkel G, Zhao H, Xue H, Xie X et al. Use of CD34+ autologous stem cell transplantation in the treatment of children with refractory systemic lupus erythematosus. Clin Rheumatol 2005; 24: 464\u2013468.","journal-title":"Clin Rheumatol"},{"key":"BFbmt200864_CR26","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1093\/rheumatology\/39.5.556","volume":"39","author":"I Foeldvari","year":"2000","unstructured":"Foeldvari I, Zhavania M, Birdi N, Cuttica RJ, de Oliveira SHF, Dent PB et al. Favourable outcome in 135 children with juvenile systemic sclerosis: results of a multinational survey. Rheumatology 2000; 39: 556\u2013569.","journal-title":"Rheumatology"},{"key":"BFbmt200864_CR27","doi-asserted-by":"publisher","first-page":"3971","DOI":"10.1002\/art.22207","volume":"54","author":"G Martini","year":"2006","unstructured":"Martini G, Foeldvari I, Russo R, Cuttica R, Eberhard A, Ravelli A et al. Systemic sclerosis in childhood: clinical and immunological features of 153 patients in an international database. Arthritis Rheum 2006; 54: 3971\u20133978.","journal-title":"Arthritis Rheum"},{"key":"BFbmt200864_CR28","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/sj.bmt.1700907","volume":"20","author":"E Raetz","year":"1997","unstructured":"Raetz E, Beatty PG, Adams RH . Treatment of Evans's syndrome with an allogeneic cord blood transplantation. Bone Marrow Transplant 1997; 20: 427\u2013429.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200864_CR29","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1038\/sj.bmt.1701785","volume":"23","author":"BU Muller","year":"1999","unstructured":"Muller BU, Tichelli A, Passweg JR, Nissen C, Wodnar-Filipowicz A, Gratwohl A . Successful treatment of refractory acquired pure red cell aplasia (PRCA) by allogeneic bone marrow transplantation. Bone Marrow Transplant 1999; 23: 1205\u20131207.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200864_CR30","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1046\/j.1365-2141.1999.01658.x","volume":"106","author":"P De Stefano","year":"1999","unstructured":"De Stefano P, Zecca M, Giorgiani G, Perotti C, Giraldi E, Locatelli F . Resolution of immune haemolytic anaemia with allogeneic bone marrow transplantation after an unsuccessful autograft. Br J Haematol 1999; 106: 1063\u20131064.","journal-title":"Br J Haematol"},{"key":"BFbmt200864_CR31","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1046\/j.1365-2141.2000.02281.x","volume":"110","author":"C Pallard","year":"2000","unstructured":"Pallard C, Kanold J, Halle P, Yakouben K, Boiret N, Rapatel C et al. Two-step immunoablative treatment with autologous PBSC transplantation in an 8-year-old boy with autoimmune haemolytic anaemia. Br J Haematol 2000; 110: 900\u2013902.","journal-title":"Br J Haematol"},{"key":"BFbmt200864_CR32","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1007\/s004310100778","volume":"160","author":"S Seeliger","year":"2001","unstructured":"Seeliger S, Baumann M, Mohr M, Jurgens H, Frosch M, Vormoor J . Autologous peripheral blood stem cell transplantation and anti-B-cell directed immunotherapy for refractory autoimmune haemolytic anaemia. Eur J Pediatr 2001; 160: 492\u2013496.","journal-title":"Eur J Pediatr"},{"key":"BFbmt200864_CR33","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1136\/adc.74.5.460","volume":"74","author":"M Cosgrove","year":"1996","unstructured":"Cosgrove M, Al-Atlas RI, Jenkins R . Epidemiology of paediatric inflammatory bowel disease. Arch Dis Child 1996; 74: 460\u2013461.","journal-title":"Arch Dis Child"},{"key":"BFbmt200864_CR34","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1053\/gast.2003.50045","volume":"124","author":"DK Bonen","year":"2003","unstructured":"Bonen DK, Cho JH . The genetics of inflammatory bowel disease. Gastroenterology 2003; 124: 521\u2013536.","journal-title":"Gastroenterology"},{"key":"BFbmt200864_CR35","doi-asserted-by":"publisher","first-page":"1556","DOI":"10.1136\/gut.2004.040824","volume":"53","author":"MP Peppelenbosch","year":"2004","unstructured":"Peppelenbosch MP, van Deventer SJ . T cell apoptosis and inflammatory bowel disease. Gut 2004; 53: 1556\u20131558.","journal-title":"Gut"},{"key":"BFbmt200864_CR36","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1053\/j.gastro.2004.11.051","volume":"128","author":"Y Oyama","year":"2005","unstructured":"Oyama Y, Craig RM, Traynor AE, Quigley K, Statkute L, Halverson A et al. Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease. Gastroenterology 2005; 128: 552\u2013563.","journal-title":"Gastroenterology"},{"key":"BFbmt200864_CR37","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1182\/blood-2005-07-2800","volume":"107","author":"I de Kleer","year":"2006","unstructured":"de Kleer I, Vastert B, Klein M, Teklenburg G, Arkesteijn G, Yung GP et al. Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network. Blood 2006; 107: 1696\u20131702.","journal-title":"Blood"},{"key":"BFbmt200864_CR38","first-page":"11","volume":"4","author":"AM Marmont","year":"2004","unstructured":"Marmont AM . Is there any evidence of a graft versus-autoimmunity effect in allogeneic transplantation? Blood Marrow Transplant Rev 2004; 4: 11.","journal-title":"Blood Marrow Transplant Rev"},{"key":"BFbmt200864_CR39","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1080\/08916930600847598","volume":"39","author":"AM Marmont","year":"2006","unstructured":"Marmont AM, Gualandi F, Occhini D, Morandi F, Ferretti E, Pezzolo A et al. Catastrophic relapse of Evans syndrome five years after allogeneic BMT notwithstanding full donor chimerism. Terminal hemolytic\u2013uremic syndrome. Autoimmunity 2006; 39: 505\u2013511.","journal-title":"Autoimmunity"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/bmt200864.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt200864","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt200864.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T07:30:10Z","timestamp":1648020610000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bmt200864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,1]]},"references-count":39,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2008,6,1]]}},"alternative-id":["BFbmt200864"],"URL":"https:\/\/doi.org\/10.1038\/bmt.2008.64","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"type":"print","value":"0268-3369"},{"type":"electronic","value":"1476-5365"}],"subject":[],"published":{"date-parts":[[2008,6,1]]},"assertion":[{"value":"11 June 2008","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}