{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:05:37Z","timestamp":1787238337243,"version":"build-2736575974"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2009,5,4]],"date-time":"2009-05-04T00:00:00Z","timestamp":1241395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2009,5,4]],"date-time":"2009-05-04T00:00:00Z","timestamp":1241395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1038\/bmt.2009.82","type":"journal-article","created":{"date-parts":[[2009,5,6]],"date-time":"2009-05-06T10:29:30Z","timestamp":1241605770000},"page":"757-763","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Allogeneic hematopoietic SCT in patients with non-malignant diseases, and importance of chimerism"],"prefix":"10.1038","volume":"44","author":[{"given":"P","family":"Svenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Mattsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Ringd\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Uzunel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,5,4]]},"reference":[{"key":"BFbmt200982_CR1","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1097\/01.tp.0000181457.43146.36","volume":"81","author":"O Ringden","year":"2006","unstructured":"Ringden O, Remberger M, Svahn BM, Barkholt L, Mattsson J, Aschan J et al. Allogeneic hematopoietic stem cell transplantation for inherited disorders: experience in a single center. Transplantation 2006; 81: 718\u2013725.","journal-title":"Transplantation"},{"key":"BFbmt200982_CR2","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1136\/adc.2005.074278","volume":"90","author":"CG Steward","year":"2005","unstructured":"Steward CG, Jarisch A . Haemopoietic stem cell transplantation for genetic disorders. Arch Dis Child 2005; 90: 1259\u20131263.","journal-title":"Arch Dis Child"},{"key":"BFbmt200982_CR3","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/sj.bmt.1704444","volume":"33","author":"P Bader","year":"2004","unstructured":"Bader P, Kreyenberg H, Hoelle W, Dueckers G, Kremens B, Dilloo D et al. Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective. Bone Marrow Transplant 2004; 33: 815\u2013821.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR4","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1097\/00007890-200102150-00017","volume":"71","author":"J Mattsson","year":"2001","unstructured":"Mattsson J, Uzunel M, Remberger M, Ringden O . T cell mixed chimerism is significantly correlated to a decreased risk of acute graft-versus-host disease after allogeneic stem cell transplantation. Transplantation 2001; 71: 433\u2013439.","journal-title":"Transplantation"},{"key":"BFbmt200982_CR5","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1046\/j.1365-2141.2001.02931.x","volume":"114","author":"PJ Amrolia","year":"2001","unstructured":"Amrolia PJ, Vulliamy T, Vassiliou G, Lawson S, Bryon J, Kaeda J et al. Analysis of chimaerism in thalassaemic children undergoing stem cell transplantation. Br J Haematol 2001; 114: 219\u2013225.","journal-title":"Br J Haematol"},{"key":"BFbmt200982_CR6","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1038\/sj.bmt.1703839","volume":"31","author":"C Peters","year":"2003","unstructured":"Peters C, Steward CG . Hematopoietic cell transplantation for inherited metabolic diseases: an overview of outcomes and practice guidelines. Bone Marrow Transplant 2003; 31: 229\u2013239.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR7","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1111\/j.1365-2141.2006.06019.x","volume":"133","author":"R Srinivasan","year":"2006","unstructured":"Srinivasan R, Takahashi Y, McCoy JP, Espinoza-Delgado I, Dorrance C, Igarashi T et al. Overcoming graft rejection in heavily transfused and allo-immunised patients with bone marrow failure syndromes using fludarabine-based haematopoietic cell transplantation. Br J Haematol 2006; 133: 305\u2013314.","journal-title":"Br J Haematol"},{"key":"BFbmt200982_CR8","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1182\/blood-2005-05-1819","volume":"107","author":"N Cooper","year":"2006","unstructured":"Cooper N, Rao K, Gilmour K, Hadad L, Adams S, Cale C et al. Stem cell transplantation with reduced-intensity conditioning for hemophagocytic lymphohistiocytosis. Blood 2006; 107: 1233\u20131236.","journal-title":"Blood"},{"key":"BFbmt200982_CR9","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.1182\/blood.V87.11.4894.bloodjournal87114894","volume":"87","author":"C Peters","year":"1996","unstructured":"Peters C, Balthazor M, Shapiro EG, King RJ, Kollman C, Hegland JD et al. Outcome of unrelated donor bone marrow transplantation in 40 children with Hurler syndrome. Blood 1996; 87: 4894\u20134902.","journal-title":"Blood"},{"key":"BFbmt200982_CR10","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1111\/j.1651-2227.2008.00811.x","volume":"97","author":"G Malm","year":"2008","unstructured":"Malm G, Gustafsson B, Berglund G, Lindstrom M, Naess K, Borgstrom B et al. Outcome in six children with mucopolysaccharidosis type IH, Hurler syndrome, after haematopoietic stem cell transplantation (HSCT). Acta Paediatr 2008; 97: 1108\u20131112.","journal-title":"Acta Paediatr"},{"key":"BFbmt200982_CR11","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/j.1399-0039.1992.tb01940.x","volume":"39","author":"O Olerup","year":"1992","unstructured":"Olerup O, Zetterquist H . HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2\u2009h: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992; 39: 225\u2013235.","journal-title":"Tissue Antigens"},{"key":"BFbmt200982_CR12","first-page":"193","volume":"1","author":"PJ Shaw","year":"1986","unstructured":"Shaw PJ, Hugh-Jones K, Hobbs JR, Downie CJ, Barnes R . Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children. Bone Marrow Transplant 1986; 1: 193\u2013200.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR13","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/j.bbmt.2006.03.002","volume":"12","author":"M Bitan","year":"2006","unstructured":"Bitan M, Or R, Shapira MY, Aker M, Resnick IB, Ackerstein A et al. Fludarabine-based reduced intensity conditioning for stem cell transplantation of Fanconi anemia patients from fully matched related and unrelated donors. Biol Blood Marrow Transplant 2006; 12: 712\u2013718.","journal-title":"Biol Blood Marrow Transplant"},{"key":"BFbmt200982_CR14","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1038\/sj.leu.2402311","volume":"15","author":"J Mattsson","year":"2001","unstructured":"Mattsson J, Uzunel M, Tammik L, Aschan J, Ringden O . Leukemia lineage-specific chimerism analysis is a sensitive predictor of relapse in patients with acute myeloid leukemia and myelodysplastic syndrome after allogeneic stem cell transplantation. Leukemia 2001; 15: 1976\u20131985.","journal-title":"Leukemia"},{"key":"BFbmt200982_CR15","doi-asserted-by":"publisher","first-page":"4618","DOI":"10.1182\/blood.V99.12.4618","volume":"99","author":"M Alizadeh","year":"2002","unstructured":"Alizadeh M, Bernard M, Danic B, Dauriac C, Birebent B, Lapart C et al. Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction. Blood 2002; 99: 4618\u20134625.","journal-title":"Blood"},{"key":"BFbmt200982_CR16","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1182\/blood-2002-05-1365","volume":"101","author":"EP Hochberg","year":"2003","unstructured":"Hochberg EP, Miklos DB, Neuberg D, Eichner DA, McLaughlin SF, Mattes-Ritz A et al. A novel rapid single nucleotide polymorphism (SNP)-based method for assessment of hematopoietic chimerism after allogeneic stem cell transplantation. Blood 2003; 101: 363\u2013369.","journal-title":"Blood"},{"key":"BFbmt200982_CR17","first-page":"788","volume":"91","author":"A Willasch","year":"2006","unstructured":"Willasch A, Hoelle W, Kreyenberg H, Niethammer D, Handgretinger R, Lang P et al. Outcome of allogeneic stem cell transplantation in children with non-malignant diseases. Haematologica 2006; 91: 788\u2013794.","journal-title":"Haematologica"},{"key":"BFbmt200982_CR18","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1097\/00007890-200408150-00015","volume":"78","author":"G Malm","year":"2004","unstructured":"Malm G, Mansson JE, Winiarski J, Mosskin M, Ringden O . Five-year follow-up of two siblings with aspartylglucosaminuria undergoing allogeneic stem-cell transplantation from unrelated donors. Transplantation 2004; 78: 415\u2013419.","journal-title":"Transplantation"},{"key":"BFbmt200982_CR19","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/sj.bmt.1705718","volume":"40","author":"JJ Boelens","year":"2007","unstructured":"Boelens JJ, Wynn RF, O\u2032Meara A, Veys P, Bertrand Y, Souillet G et al. Outcomes of hematopoietic stem cell transplantation for Hurler\u2032s syndrome in Europe: a risk factor analysis for graft failure. Bone Marrow Transplant 2007; 40: 225\u2013233.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR20","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.blre.2007.10.001","volume":"22","author":"G Lucarelli","year":"2008","unstructured":"Lucarelli G, Gaziev J . Advances in the allogeneic transplantation for thalassemia. Blood Rev 2008; 22: 53\u201363.","journal-title":"Blood Rev"},{"key":"BFbmt200982_CR21","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1046\/j.1365-2141.2001.03174.x","volume":"115","author":"J Mattsson","year":"2001","unstructured":"Mattsson J, Uzunel M, Brune M, Hentschke P, Barkholt L, Stierner U et al. Mixed chimaerism is common at the time of acute graft-versus-host disease and disease response in patients receiving non-myeloablative conditioning and allogeneic stem cell transplantation. Br J Haematol 2001; 115: 935\u2013944.","journal-title":"Br J Haematol"},{"key":"BFbmt200982_CR22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1634\/theoncologist.5-3-215","volume":"5","author":"TR Spitzer","year":"2000","unstructured":"Spitzer TR . Nonmyeloablative allogeneic stem cell transplant strategies and the role of mixed chimerism. Oncologist 2000; 5: 215\u2013223.","journal-title":"Oncologist"},{"key":"BFbmt200982_CR23","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1038\/sj.bmt.1703846","volume":"31","author":"D Valcarcel","year":"2003","unstructured":"Valcarcel D, Martino R, Caballero D, Mateos MV, Perez-Simon JA, Canals C et al. Chimerism analysis following allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning. Bone Marrow Transplant 2003; 31: 387\u2013392.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR24","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1002\/ajh.20862","volume":"82","author":"AP Jillella","year":"2007","unstructured":"Jillella AP, Shafer D, Klumpp TR, Emmons RV, Mangan KF . Mixed chimerism and graft failure following conditioning with the fludarabine and cyclophosphamide nonablative regimen; conversion to full donor chimerism. Am J Hematol 2007; 82: 419\u2013426.","journal-title":"Am J Hematol"},{"key":"BFbmt200982_CR25","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1038\/sj.bmt.1704337","volume":"33","author":"W Hoelle","year":"2004","unstructured":"Hoelle W, Beck JF, Dueckers G, Kreyenberg H, Lang P, Gruhn B et al. Clinical relevance of serial quantitative analysis of hematopoietic chimerism after allogeneic stem cell transplantation in children for severe aplastic anemia. Bone Marrow Transplant 2004; 33: 219\u2013223.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR26","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1038\/sj.bmt.1701290","volume":"22","author":"M Remberger","year":"1998","unstructured":"Remberger M, Ringden O, Ljungman P, Hagglund H, Winiarski J, Lonnqvist B et al. Booster marrow or blood cells for graft failure after allogeneic bone marrow transplantation. Bone Marrow Transplant 1998; 22: 73\u201378.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt200982_CR27","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1046\/j.1365-2141.2000.01851.x","volume":"108","author":"M Michallet","year":"2000","unstructured":"Michallet M, Tanguy ML, Socie G, Thiebaut A, Belhabri A, Milpied N et al. Second allogeneic haematopoietic stem cell transplantation in relapsed acute and chronic leukaemias for patients who underwent a first allogeneic bone marrow transplantation: a survey of the Societe Francaise de Greffe de moelle (SFGM). Br J Haematol 2000; 108: 400\u2013407.","journal-title":"Br J Haematol"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/bmt200982.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt200982","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt200982.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T08:22:03Z","timestamp":1648023723000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bmt200982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,4]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["BFbmt200982"],"URL":"https:\/\/doi.org\/10.1038\/bmt.2009.82","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,4]]},"assertion":[{"value":"1 December 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2009","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2009","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 May 2009","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}