{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:56:30Z","timestamp":1790146590232,"version":"4.0.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,12,2]],"date-time":"2013-12-02T00:00:00Z","timestamp":1385942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,12,2]],"date-time":"2013-12-02T00:00:00Z","timestamp":1385942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1038\/bmt.2013.190","type":"journal-article","created":{"date-parts":[[2013,12,2]],"date-time":"2013-12-02T11:35:39Z","timestamp":1385984139000},"page":"397-402","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["EBV-associated post-transplant lymphoproliferative disorder after umbilical cord blood transplantation in adults with hematological diseases"],"prefix":"10.1038","volume":"49","author":[{"given":"J","family":"Sanz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Arango","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Senent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Jarque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Montesinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Sempere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Lorenzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Moscard\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Mayordomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Salavert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Ca\u00f1igral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Boluda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Salazar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J L","family":"L\u00f3pez-Hontangas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Sanz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G F","family":"Sanz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,2]]},"reference":[{"key":"BFbmt2013190_CR1","first-page":"2208","volume":"94","author":"RE Curtis","year":"1999","unstructured":"Curtis RE, Travis LB, Rowlings PA, Soci\u00e9 G, Kingma DW, Banks PM et al. Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study. Blood 1999; 94: 2208\u20132216.","journal-title":"Blood"},{"key":"BFbmt2013190_CR2","doi-asserted-by":"publisher","first-page":"2874","DOI":"10.1182\/blood-2006-03-011791","volume":"108","author":"CG Brunstein","year":"2006","unstructured":"Brunstein CG, Weisdorf DJ, DeFor T, Barker JN, Tolar J, van Burik J-A et al. Marked increased risk of Epstein\u2013Barr virus-related complications with the addition of antithymocyte globulin to a nonmyeloablative conditioning prior to unrelated umbilical cord blood transplantation. Blood 2006; 108: 2874\u20132880.","journal-title":"Blood"},{"key":"BFbmt2013190_CR3","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1038\/bmt.2012.117","volume":"48","author":"P-Y Dumas","year":"2013","unstructured":"Dumas P-Y, Ruggeri A, Robin M, Crotta A, Abraham J, Forcade E et al. Incidence and risk factors of EBV reactivation after unrelated cord blood transplantation: a Eurocord and Soci\u00e9t\u00e9 Francaise de Greffede Moelle-Therapie Cellulaire collaborative study. Bone Marrow Transplant 2013; 48: 253\u2013256.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2013190_CR4","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1038\/bmt.2012.13","volume":"47","author":"J Sanz","year":"2012","unstructured":"Sanz J, Boluda JCH, Mart\u00edn C, Gonz\u00e1lez M, Ferr\u00e1 C, Serrano D et al. Single-unit umbilical cord blood transplantation from unrelated donors in patients with hematological malignancy using busulfan, thiotepa, fludarabine and ATG as myeloablative conditioning regimen. Bone Marrow Transplant 2012; 47: 1287\u20131293.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2013190_CR5","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.bbmt.2009.09.001","volume":"16","author":"J Sanz","year":"2010","unstructured":"Sanz J, Sanz MA, Saavedra S, Lorenzo I, Montesinos P, Senent L et al. Cord blood transplantation from unrelated donors in adults with high-risk acute myeloid leukemia. Biol Blood Marrow Transplant 2010; 16: 86\u201394.","journal-title":"Biol Blood Marrow Transplant"},{"key":"BFbmt2013190_CR6","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1016\/j.bbmt.2009.03.002","volume":"15","author":"P Montesinos","year":"2009","unstructured":"Montesinos P, Sanz J, Cantero S, Lorenzo I, Mart\u00edn G, Saavedra S et al. Incidence, risk factors, and outcome of cytomegalovirus infection and disease in patients receiving prophylaxis with oral valganciclovir or intravenous ganciclovir after umbilical cord blood transplantation. Biol Blood Marrow Transplant 2009; 15: 730\u2013740.","journal-title":"Biol Blood Marrow Transplant"},{"key":"BFbmt2013190_CR7","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/bmt.2008.386","volume":"43","author":"J Styczynski","year":"2009","unstructured":"Styczynski J, Reusser P, Einsele H, de la Camara R, Cordonnier C, Ward KN et al. Management of HSV, VZV and EBV infections in patients with hematological malignancies and after SCT: guidelines from the Second European Conference on Infections in Leukemia. Bone Marrow Transplant 2009; 43: 757\u2013770.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2013190_CR8","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"SH Swerdlow","year":"2008","unstructured":"Swerdlow SH . WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 4th edn International Agency for Research on Cancer, World Health Organization: Lyon, France, 2008."},{"key":"BFbmt2013190_CR9","doi-asserted-by":"publisher","first-page":"827","DOI":"10.3324\/haematol.2008.000935","volume":"94","author":"F Moscard\u00f3","year":"2009","unstructured":"Moscard\u00f3 F, Sanz J, Senent L, Cantero S, de la Rubia J, Montesinos P et al. Impact of hematopoietic chimerism at day +14 on engraftment after unrelated donor umbilical cord blood transplantation for hematologic malignancies. Haematologica 2009; 94: 827\u2013832.","journal-title":"Haematologica"},{"key":"BFbmt2013190_CR10","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1002\/(SICI)1097-0258(19990330)18:6<695::AID-SIM60>3.0.CO;2-O","volume":"18","author":"T Gooley","year":"1999","unstructured":"Gooley T, Leisenring W, Crowley J, Storer B . Estimation of failure probabilities in the presence of competing risks: new representations of old estimators. Stat Med 1999; 18: 665\u2013706.","journal-title":"Stat Med"},{"key":"BFbmt2013190_CR11","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","volume":"94","author":"J Fine","year":"1999","unstructured":"Fine J, Gray R . A proportional hazards model for subdistribution of a competing risk. J Am Stat Assoc 1999; 94: 496\u2013509.","journal-title":"J Am Stat Assoc"},{"key":"BFbmt2013190_CR12","unstructured":"R Development Core Team R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria, 2012. ISBN 900051-07-0. http:\/\/www.R-project.org."},{"key":"BFbmt2013190_CR13","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.1365-2141.2005.05439.x","volume":"129","author":"J Cohen","year":"2005","unstructured":"Cohen J, Gandhi M, Naik P, Cubitt D, Rao K, Thaker U et al. Increased incidence of EBV-related disease following paediatric stem cell transplantation with reduced-intensity conditioning. Br J Haematol 2005; 129: 229\u2013239.","journal-title":"Br J Haematol"},{"key":"BFbmt2013190_CR14","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1038\/sj.bmt.1701468","volume":"22","author":"IN Micallef","year":"1998","unstructured":"Micallef IN, Chhanabhai M, Gascoyne RD, Shepherd JD, Fung HC, Nantel SH et al. Lymphoproliferative disorders following allogeneic bone marrow transplantation: the Vancouver experience. Bone Marrow Transplant 1998; 22: 981\u2013987.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2013190_CR15","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1097\/00007890-199501000-00016","volume":"59","author":"I Penn","year":"1995","unstructured":"Penn I, Porat G . Central nervous system lymphomas in organ allograft recipients. Transplantation 1995; 59: 240\u2013244.","journal-title":"Transplantation"},{"key":"BFbmt2013190_CR16","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/j.transproceed.2004.12.130","volume":"37","author":"JF Buell","year":"2005","unstructured":"Buell JF, Gross TG, Hanaway MJ, Trofe J, Roy-Chaudhury P, First MR et al. Posttransplant lymphoproliferative disorder: significance of central nervous system involvement. Transplant Proc 2005; 37: 954\u2013955.","journal-title":"Transplant Proc"},{"key":"BFbmt2013190_CR17","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1002\/mpo.10209","volume":"40","author":"A Sirvent-Von Bueltzingsloewen","year":"2003","unstructured":"Sirvent-Von Bueltzingsloewen A, Sirvent N, Morand P, Cassuto JP . Fatal central nervous system lesions emerging during anti-CD20 monoclonal antibody therapy (Rituximab) for a post transplantation Epstein\u2013Barr virus-linked lymphoma. Med Pediatr Oncol 2003; 40: 408\u2013409.","journal-title":"Med Pediatr Oncol"},{"key":"BFbmt2013190_CR18","doi-asserted-by":"publisher","first-page":"4992","DOI":"10.1182\/blood-2008-09-178046","volume":"113","author":"O Landgren","year":"2009","unstructured":"Landgren O, Gilbert ES, Rizzo JD, Soci\u00e9 G, Banks PM, Sobocinski KA et al. Risk factors for lymphoproliferative disorders after allogeneic hematopoietic cell transplantation. Blood 2009; 113: 4992\u20135001.","journal-title":"Blood"},{"key":"BFbmt2013190_CR19","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1016\/j.leukres.2011.06.023","volume":"35","author":"JJ Liu","year":"2011","unstructured":"Liu JJ, Zhang L, Ayala E, Field T, Ochoa-Bayona JL, Perez L et al. Human immunodeficiency virus (HIV)-negative plasmablastic lymphoma: a single institutional experience and literature review. Leuk Res 2011; 35: 1571\u20131577.","journal-title":"Leuk Res"},{"key":"BFbmt2013190_CR20","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s12185-012-1244-1","volume":"97","author":"DB Chen","year":"2013","unstructured":"Chen DB, Song QJ, Chen YX, Chen YH, Shen DH . Clinicopathologic spectrum and EBV status of post-transplant lymphoproliferative disorders after allogeneic hematopoietic stem cell transplantation. Int J Hematol 2013; 97: 117\u2013124.","journal-title":"Int J Hematol"},{"key":"BFbmt2013190_CR21","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/j.bbmt.2010.02.014","volume":"16","author":"KK Ballen","year":"2010","unstructured":"Ballen KK, Cutler C, Yeap BY, McAfee SL, Dey BR, Attar EC et al. Donor-derived second hematologic malignancies after cord blood transplantation. Biol Blood Marrow Transplant 2010; 16: 1025\u20131031.","journal-title":"Biol Blood Marrow Transplant"},{"key":"BFbmt2013190_CR22","doi-asserted-by":"publisher","first-page":"4002","DOI":"10.1182\/blood-2009-07-143545","volume":"114","author":"HE Heslop","year":"2009","unstructured":"Heslop HE . How I treat EBV lymphoproliferation. Blood 2009; 114: 4002\u20134008.","journal-title":"Blood"},{"key":"BFbmt2013190_CR23","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1007\/s11864-011-0177-x","volume":"13","author":"D Jagadeesh","year":"2012","unstructured":"Jagadeesh D, Woda BA, Draper J, Evens AM . Post transplant lymphoproliferative disorders: risk, classification, and therapeutic recommendations. Curr Treat Options Oncol 2012; 13: 122\u2013136.","journal-title":"Curr Treat Options Oncol"},{"key":"BFbmt2013190_CR24","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1423-0410.2007.00900.x","volume":"92","author":"J-A van Burik","year":"2007","unstructured":"van Burik J-A, Brunstein CG . Infectious complications following unrelated cord blood transplantation. Vox Sang 2007; 92: 289\u2013296.","journal-title":"Vox Sang"},{"key":"BFbmt2013190_CR25","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1182\/blood-2009-08-239186","volume":"115","author":"HE Heslop","year":"2010","unstructured":"Heslop HE, Slobod KS, Pule MA, Hale GA, Rousseau A, Smith CA et al. Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients. Blood 2010; 115: 925\u2013935.","journal-title":"Blood"},{"key":"BFbmt2013190_CR26","doi-asserted-by":"publisher","first-page":"5045","DOI":"10.1182\/blood-2010-04-281873","volume":"116","author":"JN Barker","year":"2010","unstructured":"Barker JN, Doubrovina E, Sauter C, Jaroscak JJ, Perales MA, Doubrovin M et al. Successful treatment of EBV-associated posttransplantation lymphoma after cord blood transplantation using third-party EBV-specific cytotoxic T lymphocytes. Blood 2010; 116: 5045\u20135049.","journal-title":"Blood"},{"key":"BFbmt2013190_CR27","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1038\/bmt.2010.238","volume":"46","author":"JE Johansson","year":"2011","unstructured":"Johansson JE, Remberger M, Lazarevic VLj, Hallb\u00f6\u00f6k H, Wahlin A, Kimby E et al. Allogeneic haematopoietic stem-cell transplantation with reduced intensity conditioning for advanced stage Hodgkin\u2019s lymphoma in Sweden: high incidence of post transplantlymphoproliferative disorder. Bone Marrow Transplant 2011; 46: 870\u2013875.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2013190_CR28","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1056\/NEJMra032015","volume":"350","author":"DA Thorley-Lawson","year":"2004","unstructured":"Thorley-Lawson DA, Gross A . Persistence of the Epstein\u2013Barr virus and the origins of associated lymphomas. N Engl J Med 2004; 350: 1328\u20131337.","journal-title":"N Engl J Med"},{"key":"BFbmt2013190_CR29","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1158\/1078-0432.CCR-05-2008","volume":"12","author":"MK Gandhi","year":"2006","unstructured":"Gandhi MK, Lambley E, Burrows J, Dua U, Elliott S, Shaw PJ et al. Plasma Epstein\u2013Barr virus (EBV) DNA is a biomarker for EBV-positive Hodgkin\u2019s lymphoma. Clin Cancer Res 2006; 12: 460\u2013464.","journal-title":"Clin Cancer Res"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/bmt2013190.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt2013190","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt2013190.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T20:33:07Z","timestamp":1716237187000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bmt2013190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,2]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["BFbmt2013190"],"URL":"https:\/\/doi.org\/10.1038\/bmt.2013.190","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,2]]},"assertion":[{"value":"18 July 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2013","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}