{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:18:06Z","timestamp":1780046286060,"version":"3.53.1"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T00:00:00Z","timestamp":1407715200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T00:00:00Z","timestamp":1407715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1038\/bmt.2014.130","type":"journal-article","created":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T14:59:35Z","timestamp":1407769175000},"page":"1278-1286","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Outcomes of stem cell transplant patients with acute respiratory failure requiring mechanical ventilation in the United States"],"prefix":"10.1038","volume":"49","author":[{"given":"V","family":"Allareddy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Rampa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M K","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R P","family":"Nalliah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Allareddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A T","family":"Rotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"BFbmt2014130_CR1","first-page":"2526","volume":"307","author":"The ARDS Definition Task Force","year":"2012","unstructured":"The ARDS Definition Task Force. Acute Respiratory Distress Syndrome: The Berlin Definition. JAMA 2012; 307: 2526\u20132533.","journal-title":"JAMA"},{"issue":"Part 1","key":"BFbmt2014130_CR2","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1164\/ajrccm.149.3.7509706","volume":"149","author":"GR Bernard","year":"1994","unstructured":"Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, et al. The American\u2013European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J RespirCrit Care Med 1994; 149 (Part 1): 818\u2013824.","journal-title":"Am J RespirCrit Care Med"},{"key":"BFbmt2014130_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00075198-200402000-00001","volume":"10","author":"F Frutos-Vivar","year":"2004","unstructured":"Frutos-Vivar F, Nin N, Esteban A . Epidemiology of acute lung injury and acute respiratory distress syndrome. Curr Opin Crit Care 2004; 10: 1.","journal-title":"Curr Opin Crit Care"},{"key":"BFbmt2014130_CR4","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1097\/00075198-200502000-00007","volume":"11","author":"NS MacCallum","year":"2005","unstructured":"MacCallum NS, Evans TW . Epidemiology of acute lung injury. Curr Opin Crit Care 2005; 11: 43.","journal-title":"Curr Opin Crit Care"},{"key":"BFbmt2014130_CR5","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1378\/chest.128.2.525","volume":"128","author":"RD Stapleton","year":"2005","unstructured":"Stapleton RD, Wang BM, Hudson LD, Rubenfeld GD, Caldwell ES, Steinberg KP . Causes and timing of death in patients with ARDS. Chest 2005; 128: 525.","journal-title":"Chest"},{"key":"BFbmt2014130_CR6","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1001\/jama.287.3.345","volume":"287","author":"A Esteban","year":"2002","unstructured":"Esteban A, Anzueto A, Frutos F, Al\u00eda I, Brochard L, Stewart TE, et al. Mechanical Ventilation International Study Group. Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA 2002; 287: 345.","journal-title":"JAMA"},{"key":"BFbmt2014130_CR7","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1378\/chest.07-2134","volume":"133","author":"M Zambon","year":"2008","unstructured":"Zambon M, Vincent JL . Mortality rates for patients with acute lung injury\/ARDS have decreased over time. Chest 2008; 133: 1120.","journal-title":"Chest"},{"key":"BFbmt2014130_CR8","doi-asserted-by":"publisher","first-page":"1932","DOI":"10.1007\/s00134-011-2380-4","volume":"37","author":"J Villar","year":"2011","unstructured":"Villar J, Blanco J, A\u00f1\u00f3n JM, Santos-Bouza A, Blanch L, Ambr\u00f3s A, et al. ALIEN Network. The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intens Care Med 2011; 37: 1932.","journal-title":"Intens Care Med"},{"key":"BFbmt2014130_CR9","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1164\/rccm.201212-2169OC","volume":"188","author":"A Esteban","year":"2013","unstructured":"Esteban A, Frutos-Vivar F, Muriel A, Ferguson ND, Pe\u00f1uelas O, Abraira V, et al. Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med 2013; 188: 220.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFbmt2014130_CR10","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1097\/CCM.0b013e31819fefdf","volume":"37","author":"SE Erickson","year":"2009","unstructured":"Erickson SE, Martin GS, Davis JL, Matthay MA, Eisner MD, NIH NHLBI ARDS Network. Recent trends in acute lung injury mortality: 1996\u20132005. Crit Care Med 2009; 37 1574.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR11","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1097\/00003246-200005000-00011","volume":"28","author":"T Staudinger","year":"2000","unstructured":"Staudinger T, Stoiser B, M\u00fcllner M, Locker GJ, Laczika K, Knapp S, et al. Outcome and prognostic factors in critically ill cancer patients admitted to the intensive care unit. Crit Care Med 2000; 28: 1322.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR12","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1001\/archinte.1982.00340160107022","volume":"142","author":"MJ Hauser","year":"1982","unstructured":"Hauser MJ, Tabak J, Baier H . Survival of patients with cancer in a medical critical care unit. Arch Intern Med 1982; 142: 527.","journal-title":"Arch Intern Med"},{"key":"BFbmt2014130_CR13","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1097\/00003246-198808000-00005","volume":"16","author":"W Butt","year":"1988","unstructured":"Butt W, Barker G, Walker C, Gillis J, Kilham H, Stevens M . Outcome of children with hematologic malignancy who are admitted to an intensive care unit. Crit Care Med 1988; 16: 761.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR14","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1097\/01.md.0000145370.63676.fb","volume":"83","author":"E Azoulay","year":"2004","unstructured":"Azoulay E, Thi\u00e9ry G, Chevret S, Moreau D, Darmon M, Bergeron A, et al. The prognosis of acute respiratory failure in critically ill cancer patients. Medicine (Baltimore, MD) 2004; 83: 360.","journal-title":"Medicine (Baltimore, MD)"},{"key":"BFbmt2014130_CR15","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1097\/01.CCM.0000155783.46747.04","volume":"33","author":"M Soares","year":"2005","unstructured":"Soares M, Salluh JI, Spector N, Rocco JR . Characteristics and outcomes of cancer patients requiring mechanical ventilatory support for &gt;24\u2009h. Crit Care Med 2005; 33: 520.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR16","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1378\/chest.94.1.99","volume":"94","author":"S Peters","year":"1988","unstructured":"Peters S, Meadows A, Gracey D . Outcome of respiratory failure in hematologic malignancy. Chest 1988; 94: 99.","journal-title":"Chest"},{"key":"BFbmt2014130_CR17","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1097\/00003246-198401000-00007","volume":"12","author":"R Estopa","year":"1984","unstructured":"Estopa R, Torres Marti A, Kastanos N, Rives A, Agusti-Vidal A, Rozman C, et al. Acute respiratory failure in severe hematologic disorders. Crit Care Med 1984; 12: 26.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR18","first-page":"501","volume":"12","author":"K Faber-Langendoen","year":"1993","unstructured":"Faber-Langendoen K, Caplan AL, McGlave PB . Survival of adult bone marrow transplant patients receiving mechanical ventilation: a case for restricted use. Bone Marrow Transplant 1993; 12: 501.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2014130_CR19","doi-asserted-by":"publisher","first-page":"625","DOI":"10.7326\/0003-4819-125-8-199610150-00001","volume":"125","author":"GD Rubenfeld","year":"1996","unstructured":"Rubenfeld GD, Crawford SW . Withdrawing life support from mechanically ventilated recipients of bone marrow transplants: a case for evidence-based guidelines. Ann Intern Med 1996; 125: 625.","journal-title":"Ann Intern Med"},{"key":"BFbmt2014130_CR20","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1164\/ajrccm\/145.3.510","volume":"145","author":"SW Crawford","year":"1992","unstructured":"Crawford SW, Petersen FB . Long-term survival from respiratory failure after marrow transplantation for malignancy. Am Rev Respir Dis 1992; 145: 510.","journal-title":"Am Rev Respir Dis"},{"key":"BFbmt2014130_CR21","unstructured":"Pasquini MC, Wang Z Current use and outcome of hematopoietic stem cell transplantation: CIBMTR Summary Slides. 2012. Available at: http:\/\/www.cibmtr.org. Date of access December 1st 2013."},{"key":"BFbmt2014130_CR22","unstructured":"The Agency for Health Care Research and Quality. Nationwide Inpatient Sample. Available at: http:\/\/www.hcup-us.ahrq.gov\/db\/nation\/nis\/nisdbdocumentation.jsp. Date of access July 2013."},{"key":"BFbmt2014130_CR23","unstructured":"Bureau of Labor Statistics. Consumer price index inflation rate calculator for hospital inpatient care. Available at: http:\/\/www.bls.gov\/data\/inflation_calculator.htm (accessed on 16 October 2013)."},{"key":"BFbmt2014130_CR24","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S0025-6196(12)61310-X","volume":"67","author":"B Afessa","year":"1992","unstructured":"Afessa B, Tefferi A, Hoagland HC, Letendre L, Peters SG . Outcome of recipients of bone marrow transplants who require intensive-care unit support. Mayo Clin Proc 1992; 67: 117.","journal-title":"Mayo Clin Proc"},{"key":"BFbmt2014130_CR25","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1378\/chest.104.2.527","volume":"104","author":"HL Paz","year":"1993","unstructured":"Paz HL, Crilley P, Weinar M, Brodsky I . Outcome of patients requiring medical ICU admission following bone marrow transplantation. Chest 1993; 104: 527.","journal-title":"Chest"},{"key":"BFbmt2014130_CR26","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1097\/00003246-199504000-00026","volume":"23","author":"T Bojko","year":"1995","unstructured":"Bojko T, Notterman DA, Greenwald BM, De Bruin WJ, Magid MS, Godwin T . Acute hypoxemic respiratory failure in children following bone marrow transplantation: an outcome and pathologic study. Crit Care Med 1995; 23: 755.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR27","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1097\/00003246-198901000-00002","volume":"17","author":"SJ Denardo","year":"1989","unstructured":"Denardo SJ, Oye RK, Bellamy PE . Efficacy of intensive care for bone marrow transplant patients with respiratory failure. Crit Care Med 1989; 17: 4.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR28","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1191\/0269216304pm933oa","volume":"18","author":"A Cuomo","year":"2004","unstructured":"Cuomo A, Delmastro M, Ceriana P, Nava S, Conti G, Antonelli M, et al. Noninvasive mechanical ventilation as a palliative treatment of acute respiratory failure in patients with end-stage solid cancer. Palliat Med 2004; 18: 602.","journal-title":"Palliat Med"},{"key":"BFbmt2014130_CR29","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1097\/00003246-199401000-00030","volume":"22","author":"K Todd","year":"1994","unstructured":"Todd K, Wiley F, Landaw E, Gajewski J, Bellamy PE, Harrison RE, et al. Survival outcome among 54 intubated pediatric bone marrow transplant patients. Crit Care Med 1994; 22: 171.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR30","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1097\/00003246-200003000-00036","volume":"28","author":"HT Keenan","year":"2000","unstructured":"Keenan HT, Bratton SL, Martin LD, Crawford SW, Weiss NS . Outcome of children who require mechanical ventilatory support after bone marrow transplantation. Crit Care Med 2000; 28: 830.","journal-title":"Crit Care Med"},{"key":"BFbmt2014130_CR31","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1001\/jama.1980.03300270031025","volume":"243","author":"H Davis 2d","year":"1980","unstructured":"Davis H 2d, Lefrak SS, Miller D, Malt S . Prolonged mechanically assisted ventilation. An analysis of outcome and charges. JAMA 1980; 243: 43\u201345.","journal-title":"JAMA"},{"key":"BFbmt2014130_CR32","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1378\/chest.90.3.364","volume":"90","author":"DJ Gillespie","year":"1986","unstructured":"Gillespie DJ, Marsh HM, Divertie MB, Meadows JA III . Clinical outcome of respiratory failure in patients requiring prolonged (greater than 24\u2009h) mechanical ventilation. Chest 1986; 90: 364\u2013369.","journal-title":"Chest"},{"key":"BFbmt2014130_CR33","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1016\/j.bbmt.2012.04.001","volume":"18","author":"JM Preussler","year":"2012","unstructured":"Preussler JM, Denzen EM, Majhail NS . Costs and cost-effectiveness of hematopoietic cell transplantation. Biol Blood Marrow Transplant 2012; 18: 1620\u20131628.","journal-title":"Biol Blood Marrow Transplant"},{"key":"BFbmt2014130_CR34","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/sj.bmt.1701065","volume":"21","author":"RM Kline","year":"1998","unstructured":"Kline RM, Meiman S, Tarantino MD, Herzig RH, Bertolone SJ Jr . A detailed analysis of charges for hematopoietic stem cell transplantation at a children's hospital. Bone Marrow Transplant 1998; 21: 195\u2013203.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2014130_CR35","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1038\/bmt.2009.236","volume":"45","author":"ZY Lim","year":"2010","unstructured":"Lim ZY, Ingram W, Brand R, Ho A, Kenyon M, Devereux S, et al. Impact of pretransplant comorbidities on alemtuzumab-based reduced-intensity conditioning allogeneic hematopoietic SCT for patients with high-risk myelodysplastic syndrome and AML. Bone Marrow Transplant 2010; 45: 633\u2013639.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2014130_CR36","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1038\/bmt.2011.138","volume":"47","author":"SW Bokhari","year":"2012","unstructured":"Bokhari SW, Watson L, Nagra S, Cook M, Byrne JL, Craddock C, et al. Role of HCT-comorbidity index, age and disease status at transplantation in predicting survival and non-relapse mortality in patients with myelodysplasia and leukemia undergoing reduced-intensity-conditioning hemopoeitic progenitor cell transplantation. Bone Marrow Transplant 2012; 47: 528\u2013534.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2014130_CR37","doi-asserted-by":"publisher","first-page":"4246","DOI":"10.1200\/JCO.2006.09.7865","volume":"25","author":"ML Sorror","year":"2007","unstructured":"Sorror ML, Sandmaier BM, Storer BE, Maris MB, Baron F, Maloney DG, et al. Comorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation. J Clin Oncol 2007; 25: 4246\u20134254.","journal-title":"J Clin Oncol"},{"key":"BFbmt2014130_CR38","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1016\/j.bbmt.2008.06.008","volume":"14","author":"NS Majhail","year":"2008","unstructured":"Majhail NS, Brunstein CG, McAvoy S, DeFor TE, Al-Hazzouri A, Setubal D, et al. Does the hematopoietic cell transplantation specific comorbidity index predict transplant outcomes? A validation study in a large cohort of umbilical cord blood and matched related donor transplants. Biol Blood Marrow Transplant 2008; 14: 985\u2013992.","journal-title":"Biol Blood Marrow Transplant"},{"key":"BFbmt2014130_CR39","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/bmt.2008.300","volume":"43","author":"R Guilfoyle","year":"2009","unstructured":"Guilfoyle R, Demers A, Bredeson C, Richardson E, Rubinger M, Szwajcer D, et al. Performance status, but not the Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI), predicts mortality at a Canadian transplant center. Bone Marrow Transplant 2009; 43: 133\u2013139.","journal-title":"Bone Marrow Transplant"},{"key":"BFbmt2014130_CR40","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1038\/bmt.2009.275","volume":"45","author":"TE Defor","year":"2010","unstructured":"Defor TE, Majhail NS, Weisdorf DJ, Brunstein CG, McAvoy S, Arora M, et al. A modified comorbidity index for hematopoietic cell transplantation. Bone Marrow Transplant 2010; 45: 933\u2013938.","journal-title":"Bone Marrow Transplant"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/bmt2014130.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt2014130","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/bmt2014130.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T17:18:00Z","timestamp":1648055880000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/bmt2014130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,11]]},"references-count":40,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["BFbmt2014130"],"URL":"https:\/\/doi.org\/10.1038\/bmt.2014.130","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,11]]},"assertion":[{"value":"3 March 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2014","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2014","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2014","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}