{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:18:49Z","timestamp":1791256729866,"version":"4.1.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2008,2,29]],"date-time":"2008-02-29T00:00:00Z","timestamp":1204243200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Death Differ"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1038\/cdd.2008.25","type":"journal-article","created":{"date-parts":[[2008,2,29]],"date-time":"2008-02-29T10:25:53Z","timestamp":1204280753000},"page":"820-830","source":"Crossref","is-referenced-by-count":87,"title":["A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells"],"prefix":"10.1038","volume":"15","author":[{"given":"M","family":"Vogler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Dinsdale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X-M","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K W","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Butterworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Nicotera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J S","family":"Dyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G M","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,2,29]]},"reference":[{"key":"BFcdd200825_CR1","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1038\/sj.onc.1210220","volume":"26","author":"JM Adams","year":"2007","unstructured":"Adams JM, Cory S . The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007; 26: 1324\u20131337.","journal-title":"Oncogene"},{"key":"BFcdd200825_CR2","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/S0092-8674(04)00046-7","volume":"116","author":"NN Danial","year":"2004","unstructured":"Danial NN, Korsmeyer SJ . Cell death: critical control points. Cell 2004; 116: 205\u2013219.","journal-title":"Cell"},{"key":"BFcdd200825_CR3","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.molcel.2004.12.030","volume":"17","author":"L Chen","year":"2005","unstructured":"Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG et al. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 2005; 17: 393\u2013403.","journal-title":"Mol Cell"},{"key":"BFcdd200825_CR4","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1101\/gad.1304105","volume":"19","author":"SN Willis","year":"2005","unstructured":"Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI et al. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev 2005; 19: 1294\u20131305.","journal-title":"Genes Dev"},{"key":"BFcdd200825_CR5","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1126\/science.1133289","volume":"315","author":"SN Willis","year":"2007","unstructured":"Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE et al. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 2007; 315: 856\u2013859.","journal-title":"Science"},{"key":"BFcdd200825_CR6","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1152\/physrev.00013.2006","volume":"87","author":"G Kroemer","year":"2007","unstructured":"Kroemer G, Galluzzi L, Brenner C . Mitochondrial membrane permeabilization in cell death. Physiol Rev 2007; 87: 99\u2013163.","journal-title":"Physiol Rev"},{"key":"BFcdd200825_CR7","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s10495-007-0723-y","volume":"12","author":"A Rasola","year":"2007","unstructured":"Rasola A, Bernardi P . The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis. Apoptosis 2007; 12: 815\u2013833.","journal-title":"Apoptosis"},{"key":"BFcdd200825_CR8","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/S0092-8674(00)80450-X","volume":"91","author":"MG Vander Heiden","year":"1997","unstructured":"Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB . Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997; 91: 627\u2013637.","journal-title":"Cell"},{"key":"BFcdd200825_CR9","doi-asserted-by":"publisher","first-page":"C195","DOI":"10.1152\/ajpcell.00641.2005","volume":"291","author":"WK Lee","year":"2006","unstructured":"Lee WK, Thevenod F . A role for mitochondrial aquaporins in cellular life-and-death decisions? Am J Physiol Cell Physiol 2006; 291: C195\u2013C202.","journal-title":"Am J Physiol Cell Physiol"},{"key":"BFcdd200825_CR10","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1038\/sj.cdd.4401963","volume":"13","author":"JE Chipuk","year":"2006","unstructured":"Chipuk JE, Bouchier-Hayes L, Green DR . Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ 2006; 13: 1396\u20131402.","journal-title":"Cell Death Differ"},{"key":"BFcdd200825_CR11","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1038\/sj.cdd.4401957","volume":"13","author":"M Forte","year":"2006","unstructured":"Forte M, Bernardi P . The permeability transition and BCL-2 family proteins in apoptosis: co-conspirators or independent agents? Cell Death Differ 2006; 13: 1287\u20131290.","journal-title":"Cell Death Differ"},{"key":"BFcdd200825_CR12","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1007\/s11064-006-9252-2","volume":"32","author":"IG Gazaryan","year":"2007","unstructured":"Gazaryan IG, Brown AM . Intersection between mitochondrial permeability pores and mitochondrial fusion\/fission. Neurochem Res 2007; 32: 917\u2013929.","journal-title":"Neurochem Res"},{"key":"BFcdd200825_CR13","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1126\/science.1099320","volume":"305","author":"DR Green","year":"2004","unstructured":"Green DR, Kroemer G . The pathophysiology of mitochondrial cell death. Science 2004; 305: 626\u2013629.","journal-title":"Science"},{"key":"BFcdd200825_CR14","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/S0300-9084(02)01366-4","volume":"84","author":"AS Belzacq","year":"2002","unstructured":"Belzacq AS, Vieira HL, Kroemer G, Brenner C . The adenine nucleotide translocator in apoptosis. Biochimie 2002; 84: 167\u2013176.","journal-title":"Biochimie"},{"key":"BFcdd200825_CR15","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.2174\/0929867033457278","volume":"10","author":"AP Halestrap","year":"2003","unstructured":"Halestrap AP, Brenner C . The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death. Curr Med Chem 2003; 10: 1507\u20131525.","journal-title":"Curr Med Chem"},{"key":"BFcdd200825_CR16","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1038\/ncb1575","volume":"9","author":"CP Baines","year":"2007","unstructured":"Baines CP, Kaiser RA, Sheiko T, Craigen WJ, Molkentin JD . Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol 2007; 9: 550\u2013555.","journal-title":"Nat Cell Biol"},{"key":"BFcdd200825_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0014-5793(01)03314-2","volume":"512","author":"L He","year":"2002","unstructured":"He L, Lemasters JJ . Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? FEBS Lett 2002; 512: 1\u20137.","journal-title":"FEBS Lett"},{"key":"BFcdd200825_CR18","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1038\/nature03579","volume":"435","author":"T Oltersdorf","year":"2005","unstructured":"Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 2005; 435: 677\u2013681.","journal-title":"Nature"},{"key":"BFcdd200825_CR19","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1038\/sj.cdd.4401937","volume":"13","author":"D Zhai","year":"2006","unstructured":"Zhai D, Jin C, Satterthwait AC, Reed JC . Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins. Cell Death Differ 2006; 13: 1419\u20131421.","journal-title":"Cell Death Differ"},{"key":"BFcdd200825_CR20","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1111\/j.1365-2567.2005.02117.x","volume":"114","author":"G Packham","year":"2005","unstructured":"Packham G, Stevenson FK . Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia. Immunology 2005; 114: 441\u2013449.","journal-title":"Immunology"},{"key":"BFcdd200825_CR21","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1172\/JCI28281","volume":"117","author":"V Del Gaizo Moore","year":"2007","unstructured":"Del Gaizo Moore V, Brown JR, Certo M, Love TM, Novina CD, Letai A . Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737. J Clin Invest 2007; 117: 112\u2013121.","journal-title":"J Clin Invest"},{"key":"BFcdd200825_CR22","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1006\/excr.2000.4835","volume":"256","author":"SB Bratton","year":"2000","unstructured":"Bratton SB, MacFarlane M, Cain K, Cohen GM . Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis. Exp Cell Res 2000; 256: 27\u201333.","journal-title":"Exp Cell Res"},{"issue":"Suppl 2","key":"BFcdd200825_CR23","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1038\/sj.cdd.4401724","volume":"12","author":"G Kroemer","year":"2005","unstructured":"Kroemer G, El-Deiry WS, Golstein P, Peter ME, Vaux D, Vandenabeele P et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 2005; 12 (Suppl 2): 1463\u20131467.","journal-title":"Cell Death Differ"},{"key":"BFcdd200825_CR24","doi-asserted-by":"publisher","first-page":"C1286","DOI":"10.1152\/ajpcell.1997.272.4.C1286","volume":"272","author":"AL Nieminen","year":"1997","unstructured":"Nieminen AL, Byrne AM, Herman B, Lemasters JJ . Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species. Am J Physiol 1997; 272: C1286\u2013C1294.","journal-title":"Am J Physiol"},{"key":"BFcdd200825_CR25","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/S0006-3495(99)77239-5","volume":"76","author":"V Petronilli","year":"1999","unstructured":"Petronilli V, Miotto G, Canton M, Brini M, Colonna R, Bernardi P et al. Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence. Biophys J 1999; 76: 725\u2013734.","journal-title":"Biophys J"},{"key":"BFcdd200825_CR26","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1038\/sj.leu.2402201","volume":"15","author":"JB Almond","year":"2001","unstructured":"Almond JB, Snowden RT, Hunter A, Dinsdale D, Cain K, Cohen GM . Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700\u2009kDa Apaf-1 containing apoptosome complex. Leukemia 2001; 15: 1388\u20131397.","journal-title":"Leukemia"},{"key":"BFcdd200825_CR27","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1038\/sj.leu.2403088","volume":"17","author":"RT Snowden","year":"2003","unstructured":"Snowden RT, Sun XM, Dyer MJ, Cohen GM . Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1. Leukemia 2003; 17: 1981\u20131989.","journal-title":"Leukemia"},{"key":"BFcdd200825_CR28","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S0960-894X(00)00051-2","volume":"10","author":"GR Brown","year":"2000","unstructured":"Brown GR, Bamford AM, Bowyer J, James DS, Rankine N, Tang E et al. Naphthyl ketones: a new class of Janus kinase 3 inhibitors. Bioorg Med Chem Lett 2000; 10: 575\u2013579.","journal-title":"Bioorg Med Chem Lett"},{"key":"BFcdd200825_CR29","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.ccr.2006.08.027","volume":"10","author":"MF van Delft","year":"2006","unstructured":"van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE et al. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak\/Bax if Mcl-1 is neutralized. Cancer Cell 2006; 10: 389\u2013399.","journal-title":"Cancer Cell"},{"key":"BFcdd200825_CR30","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1177\/002215549804601009","volume":"46","author":"S Angermuller","year":"1998","unstructured":"Angermuller S, Kunstle G, Tiegs G . Pre-apoptotic alterations in hepatocytes of TNFalpha-treated galactosamine-sensitized mice. J Histochem Cytochem 1998; 46: 1175\u20131183.","journal-title":"J Histochem Cytochem"},{"key":"BFcdd200825_CR31","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1002\/hep.510310318","volume":"31","author":"G Feldmann","year":"2000","unstructured":"Feldmann G, Haouzi D, Moreau A, Durand-Schneider AM, Bringuier A, Berson A et al. Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice. Hepatology 2000; 31: 674\u2013683.","journal-title":"Hepatology"},{"key":"BFcdd200825_CR32","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1002\/ar.a.20134","volume":"281","author":"A Sesso","year":"2004","unstructured":"Sesso A, Marques MM, Monteiro MM, Schumacher RI, Colquhoun A, Belizario J et al. Morphology of mitochondrial permeability transition: morphometric volumetry in apoptotic cells. Anat Rec A Discov Mol Cell Evol Biol 2004; 281: 1337\u20131351.","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"key":"BFcdd200825_CR33","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00232-005-0838-4","volume":"209","author":"ED Burg","year":"2006","unstructured":"Burg ED, Remillard CV, Yuan JX . K+ channels in apoptosis. J Membr Biol 2006; 209: 3\u201320.","journal-title":"J Membr Biol"},{"key":"BFcdd200825_CR34","doi-asserted-by":"publisher","first-page":"C157","DOI":"10.1152\/ajpcell.00272.2006","volume":"292","author":"A Kaasik","year":"2007","unstructured":"Kaasik A, Safiulina D, Zharkovsky A, Veksler V . Regulation of mitochondrial matrix volume. Am J Physiol Cell Physiol 2007; 292: C157\u2013C163.","journal-title":"Am J Physiol Cell Physiol"},{"key":"BFcdd200825_CR35","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S1567-7249(01)00039-3","volume":"1","author":"RA Eliseev","year":"2002","unstructured":"Eliseev RA, Gunter KK, Gunter TE . Bcl-2 sensitive mitochondrial potassium accumulation and swelling in apoptosis. Mitochondrion 2002; 1: 361\u2013370.","journal-title":"Mitochondrion"},{"key":"BFcdd200825_CR36","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1083\/jcb.153.6.1265","volume":"153","author":"A Nechushtan","year":"2001","unstructured":"Nechushtan A, Smith CL, Lamensdorf I, Yoon SH, Youle RJ . Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J Cell Biol 2001; 153: 1265\u20131276.","journal-title":"J Cell Biol"},{"key":"BFcdd200825_CR37","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.cell.2006.06.025","volume":"126","author":"C Frezza","year":"2006","unstructured":"Frezza C, Cipolat S, Martins de Brito O, Micaroni M, Beznoussenko GV, Rudka T et al. OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell 2006; 126: 177\u2013189.","journal-title":"Cell"},{"key":"BFcdd200825_CR38","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S1534-5807(01)00116-2","volume":"2","author":"L Scorrano","year":"2002","unstructured":"Scorrano L, Ashiya M, Buttle K, Weiler S, Oakes SA, Mannella CA et al. A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. Dev Cell 2002; 2: 55\u201367.","journal-title":"Dev Cell"},{"key":"BFcdd200825_CR39","doi-asserted-by":"publisher","first-page":"2374","DOI":"10.1038\/sj.onc.1210028","volume":"26","author":"D Chauhan","year":"2007","unstructured":"Chauhan D, Velankar M, Brahmandam M, Hideshima T, Podar K, Richardson P et al. A novel Bcl-2\/Bcl-X(L)\/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma. Oncogene 2007; 26: 2374\u20132380.","journal-title":"Oncogene"},{"key":"BFcdd200825_CR40","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1158\/0008-5472.CAN-06-3964","volume":"67","author":"S Chen","year":"2007","unstructured":"Chen S, Dai Y, Harada H, Dent P, Grant S . Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation. Cancer Res 2007; 67: 782\u2013791.","journal-title":"Cancer Res"},{"key":"BFcdd200825_CR41","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1038\/sj.leu.2404719","volume":"21","author":"MP Kline","year":"2007","unstructured":"Kline MP, Rajkumar SV, Timm MM, Kimlinger TK, Haug JL, Lust JA et al. ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells. Leukemia 2007; 21: 1549\u20131560.","journal-title":"Leukemia"},{"key":"BFcdd200825_CR42","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1158\/0008-5472.CAN-06-2203","volume":"67","author":"SK Tahir","year":"2007","unstructured":"Tahir SK, Yang X, Anderson MG, Morgan-Lappe SE, Sarthy AV, Chen J et al. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res 2007; 67: 1176\u20131183.","journal-title":"Cancer Res"},{"key":"BFcdd200825_CR43","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1158\/1078-0432.CCR-06-1526","volume":"13","author":"S Trudel","year":"2007","unstructured":"Trudel S, Stewart AK, Li Z, Shu Y, Liang SB, Trieu Y et al. The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan. Clin Cancer Res 2007; 13: 621\u2013629.","journal-title":"Clin Cancer Res"},{"key":"BFcdd200825_CR44","doi-asserted-by":"publisher","first-page":"2908","DOI":"10.1158\/0008-5472.CAN-07-0082","volume":"67","author":"Y Dai","year":"2007","unstructured":"Dai Y, Grant S . Targeting multiple arms of the apoptotic regulatory machinery. Cancer Res 2007; 67: 2908\u20132911.","journal-title":"Cancer Res"},{"key":"BFcdd200825_CR45","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.ccr.2006.10.006","volume":"10","author":"M Konopleva","year":"2006","unstructured":"Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell 2006; 10: 375\u2013388.","journal-title":"Cancer Cell"},{"key":"BFcdd200825_CR46","doi-asserted-by":"publisher","first-page":"3972","DOI":"10.1038\/sj.onc.1210166","volume":"26","author":"X Lin","year":"2007","unstructured":"Lin X, Morgan-Lappe S, Huang X, Li L, Zakula DM, Vernetti LA et al. \u2018Seed\u2019 analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2\/Bcl-X(L) inhibitor ABT-737. Oncogene 2007; 26: 3972\u20133979.","journal-title":"Oncogene"},{"key":"BFcdd200825_CR47","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1038\/sj.cdd.4400440","volume":"5","author":"J Zhuang","year":"1998","unstructured":"Zhuang J, Dinsdale D, Cohen GM . Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential. Cell Death Differ 1998; 5: 953\u2013962.","journal-title":"Cell Death Differ"},{"key":"BFcdd200825_CR48","doi-asserted-by":"publisher","first-page":"8149","DOI":"10.1038\/sj.onc.1206053","volume":"21","author":"LA Shchepina","year":"2002","unstructured":"Shchepina LA, Pletjushkina OY, Avetisyan AV, Bakeeva LE, Fetisova EK, Izyumov DS et al. Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. Oncogene 2002; 21: 8149\u20138157.","journal-title":"Oncogene"},{"issue":"Suppl 2","key":"BFcdd200825_CR49","doi-asserted-by":"publisher","first-page":"S193","DOI":"10.1038\/sj.cdd.4401535","volume":"11","author":"S Inoue","year":"2004","unstructured":"Inoue S, MacFarlane M, Harper N, Wheat LM, Dyer MJ, Cohen GM . Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies. Cell Death Differ 2004; 11 (Suppl 2): S193\u2013S206.","journal-title":"Cell Death Differ"}],"container-title":["Cell Death & Differentiation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/cdd200825.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cdd200825","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cdd200825.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:44:09Z","timestamp":1684417449000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cdd200825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,29]]},"references-count":49,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["BFcdd200825"],"URL":"https:\/\/doi.org\/10.1038\/cdd.2008.25","relation":{},"ISSN":["1350-9047","1476-5403"],"issn-type":[{"value":"1350-9047","type":"print"},{"value":"1476-5403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,29]]}}}