{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T09:30:53Z","timestamp":1771752653898,"version":"3.50.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T00:00:00Z","timestamp":1394755200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Death Differ"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1038\/cdd.2014.21","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T15:27:14Z","timestamp":1394810834000},"page":"990-997","source":"Crossref","is-referenced-by-count":41,"title":["Disruption of the temporally regulated cloaca endodermal \u03b2-catenin signaling causes anorectal malformations"],"prefix":"10.1038","volume":"21","author":[{"given":"S","family":"Miyagawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Matsumaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Nakahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Haraguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Nakagata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R C-L","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Akita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V C-H","family":"Lui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,3,14]]},"reference":[{"key":"BFcdd201421_CR1","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1242\/dev.129.3.551","volume":"129","author":"P de Santa Barbara","year":"2002","unstructured":"de Santa Barbara P, Roberts D . Tail gut endoderm and gut\/genitourinary\/tail development: a new tissue-specific role for Hoxa13. Development 2002; 129: 551\u2013561.","journal-title":"Development"},{"key":"BFcdd201421_CR2","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/S0022-3468(00)90014-9","volume":"35","author":"S Kimmel","year":"2000","unstructured":"Kimmel S, Mo R, Hui C, Kim P . New mouse models of congenital anorectal malformations. J Pediatr Surg 2000; 35: 227\u2013230 discussion 230-1.","journal-title":"J Pediatr Surg"},{"key":"BFcdd201421_CR3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.bjps.2003.08.019","volume":"57","author":"PJ Hynes","year":"2004","unstructured":"Hynes PJ, Fraher JP . The development of the male genitourinary system. I. The origin of the urorectal septum and the formation of the perineum. Br J Plast Surg 2004; 57: 27\u201336.","journal-title":"Br J Plast Surg"},{"key":"BFcdd201421_CR4","first-page":"423","volume":"95","author":"JG Forsberg","year":"1961","unstructured":"Forsberg JG . On the development of the cloaca and the perineum and the formation of the urethral plate in female rat embryos. J Anat 1961; 95: 423\u2013436.","journal-title":"J Anat"},{"key":"BFcdd201421_CR5","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1002\/ar.a.20062","volume":"279","author":"C Sasaki","year":"2004","unstructured":"Sasaki C, Yamaguchi K, Akita K . Spatiotemporal distribution of apoptosis during normal cloacal development in mice. Anat Rec A 2004; 279: 761\u2013767.","journal-title":"Anat Rec A"},{"key":"BFcdd201421_CR6","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.ydbio.2008.03.017","volume":"318","author":"AW Seifert","year":"2008","unstructured":"Seifert AW, Harfe BD, Cohn MJ . Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. Dev Biol 2008; 318: 143\u2013152.","journal-title":"Dev Biol"},{"key":"BFcdd201421_CR7","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1242\/dev.128.21.4241","volume":"128","author":"R Haraguchi","year":"2001","unstructured":"Haraguchi R, Mo R, Hui C, Motoyama J, Makino S, Shiroishi T et al. Unique functions of Sonic hedgehog signaling during external genitalia development. Development 2001; 128: 4241\u20134250.","journal-title":"Development"},{"key":"BFcdd201421_CR8","doi-asserted-by":"publisher","first-page":"3969","DOI":"10.1242\/dev.039438","volume":"136","author":"S Miyagawa","year":"2009","unstructured":"Miyagawa S, Moon A, Haraguchi R, Inoue C, Harada M, Nakahara C et al. Dosage-dependent hedgehog signals integrated with Wnt\/beta-catenin signaling regulate external genitalia formation as an appendicular program. Development 2009; 136: 3969\u20133978.","journal-title":"Development"},{"key":"BFcdd201421_CR9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1038\/ncomms1020","volume":"1","author":"AW Seifert","year":"2010","unstructured":"Seifert AW, Zheng Z, Ormerod BK, Cohn MJ . Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics. Nat Commun 2010; 1: 23.","journal-title":"Nat Commun"},{"key":"BFcdd201421_CR10","doi-asserted-by":"publisher","first-page":"3949","DOI":"10.1242\/dev.042291","volume":"136","author":"AW Seifert","year":"2009","unstructured":"Seifert AW, Bouldin CM, Choi KS, Harfe BD, Cohn MJ . Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development. Development 2009; 136: 3949\u20133957.","journal-title":"Development"},{"key":"BFcdd201421_CR11","doi-asserted-by":"publisher","first-page":"3959","DOI":"10.1242\/dev.039768","volume":"136","author":"C Lin","year":"2009","unstructured":"Lin C, Yin Y, Veith GM, Fisher AV, Long F, Ma L . Temporal and spatial dissection of Shh signaling in genital tubercle development. Development 2009; 136: 3959\u20133967.","journal-title":"Development"},{"key":"BFcdd201421_CR12","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1053\/jpsu.2000.19265","volume":"35","author":"BQ Qi","year":"2000","unstructured":"Qi BQ, Williams A, Beasley S, Frizelle F . Clarification of the process of separation of the cloaca into rectum and urogenital sinus in the rat embryo. J Pediatr Surg 2000; 35: 1810\u20131816.","journal-title":"J Pediatr Surg"},{"key":"BFcdd201421_CR13","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/S0022-3468(86)80515-2","volume":"21","author":"SC van der Putte","year":"1986","unstructured":"van der Putte SC . Normal and abnormal development of the anorectum. J Pediatr Surg 1986; 21: 434\u2013440.","journal-title":"J Pediatr Surg"},{"key":"BFcdd201421_CR14","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1086\/302723","volume":"66","author":"E Belloni","year":"2000","unstructured":"Belloni E, Martucciello G, Verderio D, Ponti E, Seri M, Jasonni V et al. Involvement of the HLXB9 homeobox gene in Currarino syndrome. Am J Hum Genet 2000; 66: 312\u2013319.","journal-title":"Am J Hum Genet"},{"key":"BFcdd201421_CR15","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1038\/ng0198-81","volume":"18","author":"J Kohlhase","year":"1998","unstructured":"Kohlhase J, Wischermann A, Reichenbach H, Froster U, Engel W . Mutations in the SALL1 putative transcription factor gene cause Townes\u2013Brocks syndrome. Nat Genet 1998; 18: 81\u201383.","journal-title":"Nat Genet"},{"key":"BFcdd201421_CR16","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1086\/302238","volume":"64","author":"J Kohlhase","year":"1999","unstructured":"Kohlhase J, Taschner PE, Burfeind P, Pasche B, Newman B, Blanck C et al. Molecular analysis of SALL1 mutations in Townes\u2013Brocks syndrome. Am J Hum Genet 1999; 64: 435\u2013445.","journal-title":"Am J Hum Genet"},{"key":"BFcdd201421_CR17","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1034\/j.1399-0004.2001.600515.x","volume":"60","author":"ML Mart\u00ednez-Frias","year":"2001","unstructured":"Mart\u00ednez-Frias ML, Bermejo E, Frias JL . The VACTERL association: lessons from the Sonic hedgehog pathway. Clin Genet 2001; 60: 397\u2013398.","journal-title":"Clin Genet"},{"key":"BFcdd201421_CR18","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1053\/jpsu.2001.20722","volume":"36","author":"P Kim","year":"2001","unstructured":"Kim P, Mo R, Hui CcC . Murine models of VACTERL syndrome: role of sonic hedgehog signaling pathway. J Pediatr Surg 2001; 36: 381\u2013384.","journal-title":"J Pediatr Surg"},{"key":"BFcdd201421_CR19","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/S0002-9440(10)61747-6","volume":"159","author":"R Mo","year":"2001","unstructured":"Mo R, Kim JH, Zhang J, Chiang C, Hui CC, Kim PC . Anorectal malformations caused by defects in sonic hedgehog signaling. Am J Pathol 2001; 159: 765\u2013774.","journal-title":"Am J Pathol"},{"key":"BFcdd201421_CR20","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/j.ydbio.2004.03.027","volume":"271","author":"C Dravis","year":"2004","unstructured":"Dravis C, Yokoyama N, Chumley MJ, Cowan CA, Silvany RE, Shay J et al. Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. Dev Biol 2004; 271: 272\u2013290.","journal-title":"Dev Biol"},{"key":"BFcdd201421_CR21","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.jss.2009.03.087","volume":"156","author":"C Tai","year":"2009","unstructured":"Tai C, Sala F, Ford H, Wang K, Li C, Minoo P et al. Wnt5a knock-out mouse as a new model of anorectal malformation. J Surg Res 2009; 156: 278\u2013282.","journal-title":"J Surg Res"},{"key":"BFcdd201421_CR22","doi-asserted-by":"publisher","first-page":"e44962","DOI":"10.1371\/journal.pone.0044962","volume":"7","author":"C Garrido-Allepuz","year":"2012","unstructured":"Garrido-Allepuz C, Gonz\u00e1lez-Lamu\u00f1o D, Ros MA . Sirenomelia phenotype in bmp7;shh compound mutants: a novel experimental model for studies of caudal body malformations. PLoS One 2012; 7: e44962.","journal-title":"PLoS One"},{"key":"BFcdd201421_CR23","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1203\/PDR.0b013e3181aa304a","volume":"66","author":"M Nakata","year":"2009","unstructured":"Nakata M, Takada Y, Hishiki T, Saito T, Terui K, Sato Y et al. Induction of Wnt5a-expressing mesenchymal cells adjacent to the cloacal plate is an essential process for its proximodistal elongation and subsequent anorectal development. Pediatr Res 2009; 66: 149\u2013154.","journal-title":"Pediatr Res"},{"key":"BFcdd201421_CR24","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/S0890-6238(97)00153-6","volume":"12","author":"R Padmanabhan","year":"1998","unstructured":"Padmanabhan R . Retinoic acid-induced caudal regression syndrome in the mouse fetus. Reprod Toxicol 1998; 12: 139\u2013151.","journal-title":"Reprod Toxicol"},{"key":"BFcdd201421_CR25","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1038\/nrm3470","volume":"13","author":"C Niehrs","year":"2012","unstructured":"Niehrs C . The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol 2012; 13: 767\u2013779.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"BFcdd201421_CR26","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1002\/dvdy.22564","volume":"240","author":"C Wansleeben","year":"2011","unstructured":"Wansleeben C, Meijlink F . The planar cell polarity pathway in vertebrate development. Dev Dyn 2011; 240: 616\u2013626.","journal-title":"Dev Dyn"},{"key":"BFcdd201421_CR27","doi-asserted-by":"crossref","first-page":"3529","DOI":"10.1242\/dev.121.11.3529","volume":"121","author":"H Haegel","year":"1995","unstructured":"Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, Kemler R . Lack of beta-catenin affects mouse development at gastrulation. Development 1995; 121: 3529\u20133537.","journal-title":"Development"},{"key":"BFcdd201421_CR28","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S0092-8674(01)00336-1","volume":"105","author":"J Huelsken","year":"2001","unstructured":"Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W . Beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 2001; 105: 533\u2013545.","journal-title":"Cell"},{"key":"BFcdd201421_CR29","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/S0092-8674(00)81631-1","volume":"95","author":"U Gat","year":"1998","unstructured":"Gat U, DasGupta R, Degenstein L, Fuchs E . De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 1998; 95: 605\u2013614.","journal-title":"Cell"},{"key":"BFcdd201421_CR30","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1242\/dev.01052","volume":"131","author":"C Lo Celso","year":"2004","unstructured":"Lo Celso C, Prowse DM, Watt FM . Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development 2004; 131: 1787\u20131799.","journal-title":"Development"},{"key":"BFcdd201421_CR31","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1242\/dev.021295","volume":"136","author":"K Suzuki","year":"2009","unstructured":"Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H et al. Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling. Development 2009; 136: 367\u2013372.","journal-title":"Development"},{"key":"BFcdd201421_CR32","doi-asserted-by":"publisher","first-page":"2815","DOI":"10.1242\/dev.020586","volume":"135","author":"C Lin","year":"2008","unstructured":"Lin C, Yin Y, Long F, Ma L . Tissue-specific requirements of beta-catenin in external genitalia development. Development 2008; 135: 2815\u20132825.","journal-title":"Development"},{"key":"BFcdd201421_CR33","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1111\/cga.12001","volume":"53","author":"AR Mazahery","year":"2013","unstructured":"Mazahery AR, Suzuki K, Nagafuchi A, Miyajima M, Nakagata N, Orvis GD et al. Functional analysis of ectodermal \u03b2-catenin during external genitalia formation. Congenit Anom (Kyoto) 2013; 53: 34\u201341.","journal-title":"Congenit Anom (Kyoto)"},{"key":"BFcdd201421_CR34","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.cell.2004.07.024","volume":"118","author":"B Harfe","year":"2004","unstructured":"Harfe B, Scherz P, Nissim S, Tian H, McMahon A, Tabin C . Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 2004; 118: 517\u2013528.","journal-title":"Cell"},{"key":"BFcdd201421_CR35","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.pedhc.2007.01.001","volume":"22","author":"N Tobias","year":"2008","unstructured":"Tobias N, Mason D, Lutkenhoff M, Stoops M, Ferguson D . Management principles of organic causes of childhood constipation. J Pediatr Health Care 2008; 22: 12\u201323.","journal-title":"J Pediatr Health Care"},{"key":"BFcdd201421_CR36","doi-asserted-by":"publisher","first-page":"5931","DOI":"10.1093\/emboj\/18.21.5931","volume":"18","author":"N Harada","year":"1999","unstructured":"Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M et al. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J 1999; 18: 5931\u20135942.","journal-title":"EMBO J"},{"key":"BFcdd201421_CR37","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1053\/j.gastro.2007.04.072","volume":"133","author":"BM Kim","year":"2007","unstructured":"Kim BM, Mao J, Taketo MM, Shivdasani RA . Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology 2007; 133: 529\u2013538.","journal-title":"Gastroenterology"},{"issue":"6","key":"BFcdd201421_CR38","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1038\/cdd.2014.20","volume":"21","author":"R C-L Ng","year":"2014","unstructured":"Ng RC-L, Matsumaru D, Ho AS-H, Garcia-Barcel\u00f3 M-M, Yuan Z-W, Smith D et al. Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-\u03b2-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations. Cell Death Differ 2014 e-pub ahead of print 14 March 2014; doi:10.1038\/cdd.2014.20.","journal-title":"Cell Death & Differentiation"},{"key":"BFcdd201421_CR39","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1038\/5007","volume":"21","author":"P Soriano","year":"1999","unstructured":"Soriano P . Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21: 70\u201371.","journal-title":"Nat Genet"},{"key":"BFcdd201421_CR40","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1002\/gene.10038","volume":"32","author":"Y Mishina","year":"2002","unstructured":"Mishina Y, Hanks MC, Miura S, Tallquist MD, Behringer RR . Generation of Bmpr\/Alk3 conditional knockout mice. Genesis 2002; 32: 69\u201372.","journal-title":"Genesis"},{"key":"BFcdd201421_CR41","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1093\/oxfordjournals.jbchem.a021860","volume":"122","author":"K Araki","year":"1997","unstructured":"Araki K, Imaizumi T, Okuyama K, Oike Y, Yamamura K . Efficiency of recombination by Cre transient expression in embryonic stem cells: comparison of various promoters. J Biochem 1997; 122: 977\u2013982.","journal-title":"J Biochem"},{"key":"BFcdd201421_CR42","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1242\/dev.126.20.4557","volume":"126","author":"R DasGupta","year":"1999","unstructured":"DasGupta R, Fuchs E . Multiple roles for activated LEF\/TCF transcription complexes during hair follicle development and differentiation. Development 1999; 126: 4557\u20134568.","journal-title":"Development"},{"key":"BFcdd201421_CR43","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1242\/dev.02736","volume":"134","author":"R Haraguchi","year":"2007","unstructured":"Haraguchi R, Motoyama J, Sasaki H, Satoh Y, Miyagawa S, Nakagata N et al. Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling. Development 2007; 134: 525\u2013533.","journal-title":"Development"},{"key":"BFcdd201421_CR44","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1210\/me.2008-0478","volume":"23","author":"S Miyagawa","year":"2009","unstructured":"Miyagawa S, Satoh Y, Haraguchi R, Suzuki K, Iguchi T, Taketo MM et al. Genetic interactions of the androgen and Wnt\/beta-catenin pathways for the masculinization of external genitalia. Mol Endocrinol 2009; 23: 871\u2013880.","journal-title":"Mol Endocrinol"},{"key":"BFcdd201421_CR45","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1242\/dev.111.2.531","volume":"111","author":"CM Jones","year":"1991","unstructured":"Jones CM, Lyons KM, Hogan BL . Involvement of bone morphogenetic protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development 1991; 111: 531\u2013542.","journal-title":"Development"},{"key":"BFcdd201421_CR46","doi-asserted-by":"publisher","first-page":"10887","DOI":"10.1073\/pnas.93.20.10887","volume":"93","author":"R Feil","year":"1996","unstructured":"Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P . Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA 1996; 93: 10887\u201310890.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201421_CR47","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1006\/bbrc.1997.7124","volume":"237","author":"R Feil","year":"1997","unstructured":"Feil R, Wagner J, Metzger D, Chambon P . Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem Biophys Res Commun 1997; 237: 752\u2013757.","journal-title":"Biochem Biophys Res Commun"},{"key":"BFcdd201421_CR48","doi-asserted-by":"publisher","first-page":"4324","DOI":"10.1093\/nar\/27.22.4324","volume":"27","author":"A Indra","year":"1999","unstructured":"Indra A, Warot X, Brocard J, Bornert J, Xiao J, Chambon P et al. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res 1999; 27: 4324\u20134327.","journal-title":"Nucleic Acids Res"},{"key":"BFcdd201421_CR49","doi-asserted-by":"publisher","first-page":"e16260","DOI":"10.1371\/journal.pone.0016260","volume":"6","author":"D Matsumaru","year":"2011","unstructured":"Matsumaru D, Haraguchi R, Miyagawa S, Motoyama J, Nakagata N, Meijlink F et al. Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation. PLoS One 2011; 6: e16260.","journal-title":"PLoS One"}],"container-title":["Cell Death & Differentiation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/cdd201421.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cdd201421","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cdd201421.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:06:46Z","timestamp":1684415206000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cdd201421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,14]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["BFcdd201421"],"URL":"https:\/\/doi.org\/10.1038\/cdd.2014.21","relation":{},"ISSN":["1350-9047","1476-5403"],"issn-type":[{"value":"1350-9047","type":"print"},{"value":"1476-5403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,14]]}}}