{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:49:51Z","timestamp":1790545791385,"version":"4.1.0"},"reference-count":71,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T00:00:00Z","timestamp":1493942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Death Differ"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1038\/cdd.2017.32","type":"journal-article","created":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T14:33:19Z","timestamp":1493994799000},"page":"1029-1044","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["SLY regulates genes involved in chromatin remodeling and interacts with TBL1XR1 during sperm differentiation"],"prefix":"10.1038","volume":"24","author":[{"given":"Charlotte","family":"Moretti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Elisabetta","family":"Serrentino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00f4me","family":"Ialy-Radio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Delessard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana A","family":"Soboleva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Tores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie","family":"Leduc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Nitschk\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel R","family":"Drevet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Tremethick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1915-0717","authenticated-orcid":false,"given":"Daniel","family":"Vaiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayhan","family":"Kocer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Cocquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,5,5]]},"reference":[{"key":"BFcdd201732_CR1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.mce.2009.03.003","volume":"306","author":"W Yan","year":"2009","unstructured":"Yan W . Male infertility caused by spermiogenic defects: lessons from gene knockouts. Mol Cell Endocrinol 2009; 306: 24\u201332.","journal-title":"Mol Cell Endocrinol"},{"key":"BFcdd201732_CR2","doi-asserted-by":"crossref","first-page":"a002626","DOI":"10.1101\/cshperspect.a002626","volume":"3","author":"H White-Cooper","year":"2011","unstructured":"White-Cooper H, Davidson I . Unique aspects of transcription regulation in male germ cells. Cold Spring Harb Perspect Biol 2011; 3: a002626.","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"BFcdd201732_CR3","doi-asserted-by":"crossref","first-page":"12201","DOI":"10.1073\/pnas.1635054100","volume":"100","author":"N Schultz","year":"2003","unstructured":"Schultz N, Hamra FK, Garbers DL . A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets. Proc Natl Acad Sci USA 2003; 100: 12201\u201312206.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201732_CR4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1095\/biolreprod.103.026880","volume":"71","author":"JE Shima","year":"2004","unstructured":"Shima JE, McLean DJ, McCarrey JR, Griswold MD . The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod 2004; 71: 319\u2013330.","journal-title":"Biol Reprod"},{"key":"BFcdd201732_CR5","doi-asserted-by":"crossref","first-page":"8346","DOI":"10.1073\/pnas.0701883104","volume":"104","author":"F Chalmel","year":"2007","unstructured":"Chalmel F, Rolland AD, Niederhauser-Wiederkehr C, Chung SS, Demougin P, Gattiker A et al. The conserved transcriptome in human and rodent male gametogenesis. Proc Natl Acad Sci USA 2007; 104: 8346\u20138351.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201732_CR6","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1016\/j.celrep.2013.05.031","volume":"3","author":"M Soumillon","year":"2013","unstructured":"Soumillon M, Necsulea A, Weier M, Brawand D, Zhang X, Gu H et al. Cellular source and mechanisms of high transcriptome complexity in the mammalian testis. Cell Rep 2013; 3: 2179\u20132190.","journal-title":"Cell Rep"},{"key":"BFcdd201732_CR7","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.bbagrm.2013.08.004","volume":"1839","author":"C Rathke","year":"2014","unstructured":"Rathke C, Baarends WM, Awe S, Renkawitz-Pohl R . Chromatin dynamics during spermiogenesis. Biochim Biophys Acta 2014; 1839: 155\u2013168.","journal-title":"Biochim Biophys Acta"},{"key":"BFcdd201732_CR8","first-page":"82","volume":"28","author":"C Cho","year":"2001","unstructured":"Cho C, Willis WD, Goulding EH, Jung-Ha H, Choi YC, Hecht NB et al. Haploinsufficiency of protamine-1 or -2 causes infertility in mice. Nat Genet 2001; 28: 82\u201386.","journal-title":"Nat Genet"},{"key":"BFcdd201732_CR9","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1095\/biolreprod.102.015115","volume":"69","author":"C Cho","year":"2003","unstructured":"Cho C, Jung-Ha H, Willis WD, Goulding EH, Stein P, Xu Z et al. Protamine 2 deficiency leads to sperm DNA damage and embryo death in mice. Biol Reprod 2003; 69: 211\u2013217.","journal-title":"Biol Reprod"},{"key":"BFcdd201732_CR10","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1038\/emboj.2012.233","volume":"31","author":"J Gaucher","year":"2012","unstructured":"Gaucher J, Boussouar F, Montellier E, Curtet S, Buchou T, Bertrand S et al. Bromodomain-dependent stage-specific male genome programming by Brdt. EMBO J 2012; 31: 3809\u20133820.","journal-title":"EMBO J"},{"key":"BFcdd201732_CR11","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1101\/gad.220095.113","volume":"27","author":"E Montellier","year":"2013","unstructured":"Montellier E, Boussouar F, Rousseaux S, Zhang K, Buchou T, Fenaille F et al. Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B. Genes Dev 2013; 27: 1680\u20131692.","journal-title":"Genes Dev"},{"key":"BFcdd201732_CR12","doi-asserted-by":"crossref","first-page":"3812","DOI":"10.1038\/ncomms4812","volume":"5","author":"W Li","year":"2014","unstructured":"Li W, Wu J, Kim SY, Zhao M, Hearn SA, Zhang MQ et al. Chd5 orchestrates chromatin remodelling during sperm development. Nat Commun 2014; 5: 3812.","journal-title":"Nat Commun"},{"key":"BFcdd201732_CR13","doi-asserted-by":"crossref","first-page":"R66","DOI":"10.1186\/gb-2010-11-6-r66","volume":"11","author":"Y Yamauchi","year":"2010","unstructured":"Yamauchi Y, Riel JM, Stoytcheva Z, Burgoyne PS, Ward MA . Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage. Genome Biol 2010; 11: R66.","journal-title":"Genome Biol"},{"key":"BFcdd201732_CR14","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1095\/biolreprod.108.075382","volume":"81","author":"LN Reynard","year":"2009","unstructured":"Reynard LN, Cocquet J, Burgoyne PS . The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein. Biol Reprod 2009; 81: 250\u2013257.","journal-title":"Biol Reprod"},{"key":"BFcdd201732_CR15","doi-asserted-by":"crossref","first-page":"e1000244","DOI":"10.1371\/journal.pbio.1000244","volume":"7","author":"J Cocquet","year":"2009","unstructured":"Cocquet J, Ellis PJ, Yamauchi Y, Mahadevaiah SK, Affara NA, Ward MA et al. The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. PLoS Biol 2009; 7: e1000244.","journal-title":"PLoS Biol"},{"key":"BFcdd201732_CR16","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1242\/jcs.114488","volume":"126","author":"JM Riel","year":"2013","unstructured":"Riel JM, Yamauchi Y, Sugawara A, Li HY, Ruthig V, Stoytcheva Z et al. Deficiency of the multi-copy mouse Y gene Sly causes sperm DNA damage and abnormal chromatin packaging. J Cell Sci 2013; 126: 803\u2013813.","journal-title":"J Cell Sci"},{"key":"BFcdd201732_CR17","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1097-2765(00)80404-9","volume":"5","author":"L Yuan","year":"2000","unstructured":"Yuan L, Liu J-G, Zhao J, Brundell E, Daneholt B, H\u00f6\u00f6g C . The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility. Mol Cell 2000; 5: 73\u201383.","journal-title":"Mol Cell"},{"key":"BFcdd201732_CR18","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1038\/ncomms2995","volume":"4","author":"H Gan","year":"2013","unstructured":"Gan H, Wen L, Liao S, Lin X, Ma T, Liu J et al. Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. Nat Commun 2013; 4: 1995.","journal-title":"Nat Commun"},{"key":"BFcdd201732_CR19","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1128\/MCB.01328-14","volume":"35","author":"JM Bryant","year":"2015","unstructured":"Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH et al. Characterization of BRD4 during mammalian postmeiotic sperm development. Mol Cell Biol 2015; 35: 1433\u20131448.","journal-title":"Mol Cell Biol"},{"key":"BFcdd201732_CR20","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nsmb.2599","volume":"20","author":"S Erkek","year":"2013","unstructured":"Erkek S, Hisano M, Liang CY, Gill M, Murr R, Dieker J et al. Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa. Nat Struct Mol Biol 2013; 20: 868\u2013875.","journal-title":"Nat Struct Mol Biol"},{"key":"BFcdd201732_CR21","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.cell.2011.08.008","volume":"146","author":"M Tan","year":"2011","unstructured":"Tan M, Luo H, Lee S, Jin F, Yang JS, Montellier E et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 2011; 146: 1016\u20131028.","journal-title":"Cell"},{"key":"BFcdd201732_CR22","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.stem.2014.04.006","volume":"15","author":"SS Hammoud","year":"2014","unstructured":"Hammoud SS, Low DH, Yi C, Carrell DT, Guccione E, Cairns BR . Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis. Cell Stem Cell 2014; 15: 239\u2013253.","journal-title":"Cell Stem Cell"},{"key":"BFcdd201732_CR23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.cell.2005.01.001","volume":"120","author":"BE Bernstein","year":"2005","unstructured":"Bernstein BE, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey DK, Huebert DJ et al. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell 2005; 120: 169\u2013181.","journal-title":"Cell"},{"key":"BFcdd201732_CR24","doi-asserted-by":"crossref","first-page":"21931","DOI":"10.1073\/pnas.1016071107","volume":"107","author":"MP Creyghton","year":"2010","unstructured":"Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ et al. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci USA 2010; 107: 21931\u201321936.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201732_CR25","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.cell.2014.06.027","volume":"158","author":"BA Benayoun","year":"2014","unstructured":"Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED et al. H3K4me3 breadth is linked to cell identity and transcriptional consistency. Cell 2014; 158: 673\u2013688.","journal-title":"Cell"},{"key":"BFcdd201732_CR26","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2144\/05391RV01","volume":"39","author":"ML Wong","year":"2005","unstructured":"Wong ML, Medrano JF . Real-time PCR for mRNA quantitation. Biotechniques 2005; 39: 75\u201385.","journal-title":"Biotechniques"},{"key":"BFcdd201732_CR27","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/nsmb.2161","volume":"19","author":"TA Soboleva","year":"2011","unstructured":"Soboleva TA, Nekrasov M, Pahwa A, Williams R, Huttley GA, Tremethick DJ . A unique H2A histone variant occupies the transcriptional start site of active genes. Nat Struct Mol Biol 2011; 19: 25\u201330.","journal-title":"Nat Struct Mol Biol"},{"key":"BFcdd201732_CR28","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1083\/jcb.200604141","volume":"176","author":"J Govin","year":"2007","unstructured":"Govin J, Escoffier E, Rousseaux S, Kuhn L, Ferro M, Thevenon J et al. Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis. J Cell Biol 2007; 176: 283\u2013294.","journal-title":"J Cell Biol"},{"key":"BFcdd201732_CR29","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00335-009-9175-8","volume":"20","author":"L Ferguson","year":"2009","unstructured":"Ferguson L, Ellis PJ, Affara NA . Two novel mouse genes mapped to chromosome Yp are expressed specifically in spermatids. Mamm Genome 2009; 20: 193\u2013206.","journal-title":"Mamm Genome"},{"key":"BFcdd201732_CR30","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1073\/pnas.0406060102","volume":"102","author":"I Martianov","year":"2005","unstructured":"Martianov I, Brancorsini S, Catena R, Gansmuller A, Kotaja N, Parvinen M et al. Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis. Proc Natl Acad Sci USA 2005; 102: 2808\u20132813.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201732_CR31","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1242\/bio.20147302","volume":"3","author":"C Dottermusch-Heidel","year":"2014","unstructured":"Dottermusch-Heidel C, Gartner SM, Tegeder I, Rathke C, Barckmann B, Bartkuhn M et al. H3K79 methylation: a new conserved mark that accompanies H4 hyperacetylation prior to histone-to-protamine transition in Drosophila and rat. Biol Open 2014; 3: 444\u2013452.","journal-title":"Biol Open"},{"key":"BFcdd201732_CR32","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.2047-2927.2014.00248.x","volume":"2","author":"C Dottermusch-Heidel","year":"2014","unstructured":"Dottermusch-Heidel C, Klaus ES, Gonzalez NH, Bhushan S, Meinhardt A, Bergmann M et al. H3K79 methylation directly precedes the histone-to-protamine transition in mammalian spermatids and is sensitive to bacterial infections. Andrology 2014; 2: 655\u2013665.","journal-title":"Andrology"},{"key":"BFcdd201732_CR33","doi-asserted-by":"crossref","first-page":"e1002900","DOI":"10.1371\/journal.pgen.1002900","volume":"8","author":"J Cocquet","year":"2012","unstructured":"Cocquet J, Ellis PJ, Mahadevaiah SK, Affara NA, Vaiman D, Burgoyne PS . A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse. PLoS Genet 2012; 8: e1002900.","journal-title":"PLoS Genet"},{"key":"BFcdd201732_CR34","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nsmb.3249","volume":"23","author":"O Gilan","year":"2016","unstructured":"Gilan O, Lam EY, Becher I, Lugo D, Cannizzaro E, Joberty G et al. Functional interdependence of BRD4 and DOT1L in MLL leukemia. Nat Struct Mol Biol 2016; 23: 673\u2013681.","journal-title":"Nat Struct Mol Biol"},{"key":"BFcdd201732_CR35","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/nsmb.1821","volume":"17","author":"U Brykczynska","year":"2010","unstructured":"Brykczynska U, Hisano M, Erkek S, Ramos L, Oakeley EJ, Roloff TC et al. Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa. Nat Struct Mol Biol 2010; 17: 679\u2013687.","journal-title":"Nat Struct Mol Biol"},{"key":"BFcdd201732_CR36","first-page":"2074","volume":"119","author":"E Chabory","year":"2009","unstructured":"Chabory E, Damon C, Lenoir A, Kauselmann G, Kern H, Zevnik B et al. Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice. J Clin Invest 2009; 119: 2074\u20132085.","journal-title":"J Clin Invest"},{"key":"BFcdd201732_CR37","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12915-015-0159-8","volume":"13","author":"HS Sin","year":"2015","unstructured":"Sin HS, Kartashov AV, Hasegawa K, Barski A, Namekawa SH . Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline. BMC Biol 2015; 13: 53.","journal-title":"BMC Biol"},{"key":"BFcdd201732_CR38","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13072-016-0099-8","volume":"9","author":"C Moretti","year":"2016","unstructured":"Moretti C, Vaiman D, Tores F, Cocquet J . Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells. Epigenetics Chromatin 2016; 9: 47.","journal-title":"Epigenetics Chromatin"},{"key":"BFcdd201732_CR39","doi-asserted-by":"crossref","first-page":"e02963","DOI":"10.7554\/eLife.02963","volume":"3","author":"JL Syrjanen","year":"2014","unstructured":"Syrjanen JL, Pellegrini L, Davies OR . A molecular model for the role of SYCP3 in meiotic chromosome organisation. Elife 2014; 3: e02963.","journal-title":"Elife"},{"key":"BFcdd201732_CR40","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1093\/emboj\/19.16.4342","volume":"19","author":"J Li","year":"2000","unstructured":"Li J, Wang J, Wang J, Nawaz Z, Liu JM, Qin J et al. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J 2000; 19: 4342\u20134350.","journal-title":"EMBO J"},{"key":"BFcdd201732_CR41","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1097-2765(02)00468-9","volume":"9","author":"J Zhang","year":"2002","unstructured":"Zhang J, Kalkum M, Chait BT, Roeder RG . The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol Cell 2002; 9: 611\u2013623.","journal-title":"Mol Cell"},{"key":"BFcdd201732_CR42","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.molcel.2003.08.008","volume":"12","author":"HG Yoon","year":"2003","unstructured":"Yoon HG, Chan DW, Reynolds AB, Qin J, Wong J . N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. Mol Cell 2003; 12: 723\u2013734.","journal-title":"Mol Cell"},{"key":"BFcdd201732_CR43","doi-asserted-by":"crossref","first-page":"6404","DOI":"10.1128\/MCB.25.15.6404-6414.2005","volume":"25","author":"D Zhang","year":"2005","unstructured":"Zhang D, Yoon HG, Wong J . JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2\/Hash2). Mol Cell Biol 2005; 25: 6404\u20136414.","journal-title":"Mol Cell Biol"},{"key":"BFcdd201732_CR44","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.molcel.2008.01.020","volume":"29","author":"V Perissi","year":"2008","unstructured":"Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK et al. TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR\/SMRT transcriptional repression checkpoints. Mol Cell 2008; 29: 755\u2013766.","journal-title":"Mol Cell"},{"key":"BFcdd201732_CR45","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/nrg2736","volume":"11","author":"V Perissi","year":"2010","unstructured":"Perissi V, Jepsen K, Glass CK, Rosenfeld MG . Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet 2010; 11: 109\u2013123.","journal-title":"Nat Rev Genet"},{"key":"BFcdd201732_CR46","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1093\/hmg\/ddr204","volume":"20","author":"PJ Ellis","year":"2011","unstructured":"Ellis PJ, Bacon J, Affara NA . Association of Sly with sex-linked gene amplification during mouse evolution: a side effect of genomic conflict in spermatids? Hum Mol Genet 2011; 20: 3010\u20133021.","journal-title":"Hum Mol Genet"},{"key":"BFcdd201732_CR47","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.cell.2014.09.052","volume":"159","author":"YQ Soh","year":"2014","unstructured":"Soh YQ, Alfoldi J, Pyntikova T, Brown LG, Graves T, Minx PJ et al. Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes. Cell 2014; 159: 800\u2013813.","journal-title":"Cell"},{"key":"BFcdd201732_CR48","doi-asserted-by":"crossref","first-page":"a017616","DOI":"10.1101\/cshperspect.a017616","volume":"7","author":"Q Helleu","year":"2014","unstructured":"Helleu Q, Gerard PR, Montchamp-Moreau C . Sex chromosome drive. Cold Spring Harb Perspect Biol 2014; 7: a017616.","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"BFcdd201732_CR49","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/S0960-9822(02)00901-6","volume":"12","author":"Q Feng","year":"2002","unstructured":"Feng Q, Wang H, Ng HH, Erdjument-Bromage H, Tempst P, Struhl K et al. Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain. Curr Biol 2002; 12: 1052\u20131058.","journal-title":"Curr Biol"},{"key":"BFcdd201732_CR50","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1042\/bj20030839","volume":"377","author":"W Zhang","year":"2004","unstructured":"Zhang W, Hayashizaki Y, Kone BC . Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase. Biochem J 2004; 377: 641\u2013651.","journal-title":"Biochem J"},{"key":"BFcdd201732_CR51","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00412-013-0438-5","volume":"123","author":"D Ontoso","year":"2014","unstructured":"Ontoso D, Kauppi L, Keeney S, San-Segundo PA . Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes. Chromosoma 2014; 123: 147\u2013164.","journal-title":"Chromosoma"},{"key":"BFcdd201732_CR52","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/nsmb.3228","volume":"23","author":"BN Devaiah","year":"2016","unstructured":"Devaiah BN, Case-Borden C, Gegonne A, Hsu CH, Chen Q, Meerzaman D et al. BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin. Nat Struct Mol Biol 2016; 23: 540\u2013548.","journal-title":"Nat Struct Mol Biol"},{"key":"BFcdd201732_CR53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ydbio.2015.07.024","volume":"406","author":"T Lord","year":"2015","unstructured":"Lord T, Aitken RJ . Fertilization stimulates 8-hydroxy-2'-deoxyguanosine repair and antioxidant activity to prevent mutagenesis in the embryo. Dev Biol 2015; 406: 1\u201313.","journal-title":"Dev Biol"},{"key":"BFcdd201732_CR54","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/1008-682X.122203","volume":"16","author":"RJ Aitken","year":"2014","unstructured":"Aitken RJ, Smith TB, Jobling MS, Baker MA, De Iuliis GN . Oxidative stress and male reproductive health. Asian J Androl 2014; 16: 31\u201338.","journal-title":"Asian J Androl"},{"key":"BFcdd201732_CR55","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/bioinformatics\/btp698","volume":"26","author":"H Li","year":"2010","unstructured":"Li H, Durbin R . Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 2010; 26: 589\u2013595.","journal-title":"Bioinformatics"},{"key":"BFcdd201732_CR56","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","volume":"25","author":"H Li","year":"2009","unstructured":"Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N et al. The Sequence Alignment\/Map format and SAMtools. Bioinformatics 2009; 25: 2078\u20132079.","journal-title":"Bioinformatics"},{"key":"BFcdd201732_CR57","doi-asserted-by":"crossref","first-page":"R137","DOI":"10.1186\/gb-2008-9-9-r137","volume":"9","author":"Y Zhang","year":"2008","unstructured":"Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol 2008; 9: R137.","journal-title":"Genome Biol"},{"key":"BFcdd201732_CR58","doi-asserted-by":"crossref","first-page":"W187","DOI":"10.1093\/nar\/gku365","volume":"42","author":"F Ramirez","year":"2014","unstructured":"Ramirez F, Dundar F, Diehl S, Gruning BA, Manke T . deepTools: a flexible platform for exploring deep-sequencing data. Nucleic Acids Res 2014; 42: W187\u2013W191.","journal-title":"Nucleic Acids Res"},{"key":"BFcdd201732_CR59","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102: 15545\u201315550.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201732_CR60","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-2105-14-128","volume":"14","author":"EY Chen","year":"2013","unstructured":"Chen EY, Tan CM, Kou Y, Duan Q, Wang Z, Meirelles GV et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. BMC Bioinformatics 2013; 14: 128.","journal-title":"BMC Bioinformatics"},{"key":"BFcdd201732_CR61","doi-asserted-by":"crossref","first-page":"2936","DOI":"10.1093\/humrep\/dem292","volume":"22","author":"AN Spiess","year":"2007","unstructured":"Spiess AN, Feig C, Schulze W, Chalmel F, Cappallo-Obermann H, Primig M et al. Cross-platform gene expression signature of human spermatogenic failure reveals inflammatory-like response. Hum Reprod 2007; 22: 2936\u20132946.","journal-title":"Hum Reprod"},{"key":"BFcdd201732_CR62","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1095\/biolreprod61.5.1256","volume":"61","author":"PP Reddi","year":"1999","unstructured":"Reddi PP, Flickinger CJ, Herr JC . Round spermatid-specific transcription of the mouse SP-10 gene is mediated by a 294-base pair proximal promoter. Biol Reprod 1999; 61: 1256\u20131266.","journal-title":"Biol Reprod"},{"key":"BFcdd201732_CR63","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0012-1606(03)00349-X","volume":"262","author":"PP Reddi","year":"2003","unstructured":"Reddi PP, Shore AN, Shapiro JA, Anderson A, Stoler MH, Acharya KK . Spermatid-specific promoter of the SP-10 gene functions as an insulator in somatic cells. Dev Biol 2003; 262: 173\u2013182.","journal-title":"Dev Biol"},{"key":"BFcdd201732_CR64","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/cyto.a.20129","volume":"65","author":"H Bastos","year":"2005","unstructured":"Bastos H, Lassalle B, Chicheportiche A, Riou L, Testart J, Allemand I et al. Flow cytometric characterization of viable meiotic and postmeiotic cells by Hoechst 33342 in mouse spermatogenesis. Cytometry A 2005; 65: 40\u201349.","journal-title":"Cytometry A"},{"key":"BFcdd201732_CR65","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1111\/febs.12724","volume":"281","author":"A Comptour","year":"2014","unstructured":"Comptour A, Moretti C, Serrentino ME, Auer J, Ialy-Radio C, Ward MA et al. SSTY proteins co-localize with the post-meiotic sex chromatin and interact with regulators of its expression. FEBS J 2014; 281: 1571\u20131584.","journal-title":"FEBS J"},{"key":"BFcdd201732_CR66","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1095\/biolreprod.113.108597","volume":"89","author":"S Kuroki","year":"2013","unstructured":"Kuroki S, Akiyoshi M, Tokura M, Miyachi H, Nakai Y, Kimura H et al. JMJD1C, a JmjC domain-containing protein, is required for long-term maintenance of male germ cells in mice. Biol Reprod 2013; 89: 93.","journal-title":"Biol Reprod"},{"key":"BFcdd201732_CR67","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1093\/hmg\/ddi304","volume":"14","author":"PJI Ellis","year":"2005","unstructured":"Ellis PJI, Clemente EJ, Ball P, Toure A, Ferguson L, Turner JMA et al. Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids. Hum Mol Genet 2005; 14: 2705\u20132715.","journal-title":"Hum Mol Genet"},{"key":"BFcdd201732_CR68","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.freeradbiomed.2013.07.044","volume":"65","author":"A Noblanc","year":"2013","unstructured":"Noblanc A, Damon-Soubeyrand C, Karrich B, Henry-Berger J, Cadet R, Saez F et al. DNA oxidative damage in mammalian spermatozoa: where and why is the male nucleus affected? Free Radic Biol Med 2013; 65: 719\u2013723.","journal-title":"Free Radic Biol Med"},{"key":"BFcdd201732_CR69","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1095\/biolreprod.107.061101","volume":"77","author":"LN Reynard","year":"2007","unstructured":"Reynard LN, Turner JM, Cocquet J, Mahadevaiah SK, Toure A, Hoog C et al. Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX\/XMR. Biol Reprod 2007; 77: 329\u2013335.","journal-title":"Biol Reprod"},{"key":"BFcdd201732_CR70","doi-asserted-by":"crossref","first-page":"5311","DOI":"10.1073\/pnas.1600485113","volume":"113","author":"H Lahouassa","year":"2016","unstructured":"Lahouassa H, Blondot ML, Chauveau L, Chougui G, Morel M, Leduc M et al. HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages. Proc Natl Acad Sci USA 2016; 113: 5311\u20135316.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcdd201732_CR71","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/bies.201100141","volume":"34","author":"E Montellier","year":"2012","unstructured":"Montellier E, Rousseaux S, Zhao Y, Khochbin S . Histone crotonylation specifically marks the haploid male germ cell gene expression program: post-meiotic male-specific gene expression. BioEssays 2012; 34: 187\u2013193.","journal-title":"BioEssays"}],"container-title":["Cell Death & Differentiation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/cdd201732.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cdd201732","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/cdd.2017.32","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/cdd201732.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:13:10Z","timestamp":1684415590000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cdd201732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,5]]},"references-count":71,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["BFcdd201732"],"URL":"https:\/\/doi.org\/10.1038\/cdd.2017.32","relation":{},"ISSN":["1350-9047","1476-5403"],"issn-type":[{"value":"1350-9047","type":"print"},{"value":"1476-5403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,5]]},"assertion":[{"value":"20 September 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 January 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2017","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}