{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:19:06Z","timestamp":1772065146686,"version":"3.50.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T00:00:00Z","timestamp":1389830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"},{"start":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T00:00:00Z","timestamp":1389830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Death Dis"],"DOI":"10.1038\/cddis.2013.465","type":"journal-article","created":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T15:52:28Z","timestamp":1389887548000},"page":"e1005-e1005","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["RETRACTED ARTICLE: Osteolytic bone metastasis is hampered by impinging on the interplay among autophagy, anoikis and ossification"],"prefix":"10.1038","volume":"5","author":[{"given":"P","family":"Maroni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Bendinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Matteucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Scita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M A","family":"Desiderio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,16]]},"reference":[{"key":"BFcddis2013465_CR1","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1038\/nrc2621","volume":"9","author":"B Psaila","year":"2009","unstructured":"Psaila B, Lyden D . The metastatic niche: adapting to the foreign soil. Nat Rev Cancer 2009; 9: 285\u2013293.","journal-title":"Nat Rev Cancer"},{"key":"BFcddis2013465_CR2","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1016\/j.ejca.2010.02.036","volume":"46","author":"S Previdi","year":"2010","unstructured":"Previdi S, Maroni P, Matteucci E, Broggini M, Bendinelli P, Desiderio MA . Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor\/Met and \u03b2-catenin\/Wnt pathways. Eur J Cancer 2010; 46: 1679\u20131691.","journal-title":"Eur J Cancer"},{"key":"BFcddis2013465_CR3","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.ejca.2012.05.006","volume":"49","author":"E Matteucci","year":"2013","unstructured":"Matteucci E, Maroni P, Luzzati A, Perrucchini G, Bendinelli P, Desiderio MA . Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors. Eur J Cancer 2013; 49: 231\u2013244.","journal-title":"Eur J Cancer"},{"key":"BFcddis2013465_CR4","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.ccr.2009.05.017","volume":"16","author":"XH Zhang","year":"2009","unstructured":"Zhang XH, Wang Q, Gerald W, Hudis L, Norton M, Smid JA et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 2009; 16: 67\u201378.","journal-title":"Cancer Cell"},{"key":"BFcddis2013465_CR5","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/nrc3205","volume":"12","author":"E Gherardi","year":"2012","unstructured":"Gherardi E, Birchmeier W, Birchmeier C, Vande Woude G . Targeting Met in cancer: rationale and progress. Nat Rev Cancer 2012; 12: 89\u2013103.","journal-title":"Nat Rev Cancer"},{"key":"BFcddis2013465_CR6","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1016\/j.bbamcr.2011.06.004","volume":"1813","author":"P Bendinelli","year":"2011","unstructured":"Bendinelli P, Maroni P, Matteucci E, Desiderio MA . Comparative role of acetylation along c-SRC\/ETS1 signaling pathway in bone metastatic and invasive mammary cell phenotypes. Biochim Biophys Acta 2011; 1813: 1767\u20131776.","journal-title":"Biochim Biophys Acta"},{"key":"BFcddis2013465_CR7","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1093\/carcin\/bgp080","volume":"30","author":"E Matteucci","year":"2009","unstructured":"Matteucci E, Bendinelli P, Desiderio MA . Nuclear localization of active HGF receptor Met in aggressive MDA-MB231 breast carcinoma cells. Carcinogenesis 2009; 30: 937\u2013945.","journal-title":"Carcinogenesis"},{"key":"BFcddis2013465_CR8","doi-asserted-by":"publisher","first-page":"5706","DOI":"10.1158\/0008-5472.CAN-09-2356","volume":"70","author":"D Barkan","year":"2010","unstructured":"Barkan D, El Touny LH, Michalowski AM, Smith JA, Chu I, Davis AS et al. Metastatic growth from dormant cells induced by a Col-I-enriched fibrotic environment. Cancer Res 2010; 70: 5706\u20135716.","journal-title":"Cancer Res"},{"key":"BFcddis2013465_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/ijc.23998","volume":"124","author":"J Araujo","year":"2009","unstructured":"Araujo J, Logothetis C . Targeting Src in metastatic bone disease. Int J Cancer 2009; 124: 1\u20136.","journal-title":"Int J Cancer"},{"key":"BFcddis2013465_CR10","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1038\/nrc3055","volume":"11","author":"KN Weilbaecher","year":"2011","unstructured":"Weilbaecher KN, Guise TA, McCauley LK . Cancer to bone: a fatal attraction. Nat Rev Cancer 2011; 11: 411\u2013425.","journal-title":"Nat Rev Cancer"},{"key":"BFcddis2013465_CR11","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.semcdb.2012.04.007","volume":"23","author":"CL Buchheit","year":"2012","unstructured":"Buchheit CL, Rayavarapu RR, Schafer ZT . The regulation of cancer cell death and metabolism by extracellular matrix attachment. Semin Cell Dev Biol 2012; 23: 402\u2013411.","journal-title":"Semin Cell Dev Biol"},{"key":"BFcddis2013465_CR12","doi-asserted-by":"publisher","first-page":"537","DOI":"10.4161\/cbt.10.6.13370","volume":"10","author":"MP Lisanti","year":"2010","unstructured":"Lisanti MP, Martinez-Outschoorn UE, Chiavarina B, Pavlides S, Whitaker-Menezes D, Tsirigos A et al. Understanding the \u2018lethal\u2019 drivers of tumor\u2013stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy\/mitophagy in the tumor microenvironment. Cancer Biol Ther 2010; 10: 537\u2013542.","journal-title":"Cancer Biol Ther"},{"key":"BFcddis2013465_CR13","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s00281-010-0213-0","volume":"32","author":"S Roy","year":"2010","unstructured":"Roy S, Debnath J . Autophagy and tumorigenesis. Semin Immunopathol 2010; 32: 383\u2013396.","journal-title":"Semin Immunopathol"},{"key":"BFcddis2013465_CR14","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1038\/nrc3262","volume":"12","author":"E White","year":"2012","unstructured":"White E . Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer 2012; 12: 401\u2013410.","journal-title":"Nat Rev Cancer"},{"key":"BFcddis2013465_CR15","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.1002\/ijc.25197","volume":"127","author":"Y Suzuki","year":"2010","unstructured":"Suzuki Y, Sakai K, Ueki J, Xu Q, Nakamura T, Shimada H et al. Inhibition of Met\/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma. Int J Cancer 2010; 127: 1948\u20131957.","journal-title":"Int J Cancer"},{"key":"BFcddis2013465_CR16","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1111\/j.1349-7006.2009.01184.x","volume":"100","author":"Y Kishi","year":"2009","unstructured":"Kishi Y, Kuba K, Nakamura T, Wen J, Suzuki Y, Mizuno S et al. Systemic NK4 gene therapy inhibits tumor growth and metastasis of melanoma and lung carcinoma in syngeneic mouse tumor models. Cancer Sci 2009; 100: 1351\u20131358.","journal-title":"Cancer Sci"},{"key":"BFcddis2013465_CR17","first-page":"6737","volume":"60","author":"K Kuba","year":"2000","unstructured":"Kuba K, Matsumoto K, Date K, Shimura H, Tanaka M, Nakamura T . HGF\/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice. Cancer Res 2000; 60: 6737\u20136743.","journal-title":"Cancer Res"},{"key":"BFcddis2013465_CR18","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/aja.2010.22","volume":"12","author":"D Yue","year":"2010","unstructured":"Yue D, Wang Y, Ma P, Li Y-Y, Chen H, Wang P et al. Effects of transferred NK4 gene on proliferation, migration, invasion and apoptosis of human prostate cancer DU145 cells. Asian J Androl 2010; 12: 381\u2013389.","journal-title":"Asian J Androl"},{"key":"BFcddis2013465_CR19","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/his.12002","volume":"62","author":"J Choi","year":"2013","unstructured":"Choi J, Jung W, Koo JS . Expression of autophagy-related markers beclin-1, light chain 3A, light chain 3B and p62 according to the molecular subtype of breast cancer. Histopathology 2013; 62: 275\u2013286.","journal-title":"Histopathology"},{"key":"BFcddis2013465_CR20","doi-asserted-by":"publisher","first-page":"138","DOI":"10.4161\/auto.2.2.2405","volume":"2","author":"G Bj\u00f8rk\u00f8y","year":"2006","unstructured":"Bj\u00f8rk\u00f8y G, Lamark T, Johansen T . p62\/SQSTM1: a missing link between protein aggregates and the autophagy machinery. Autophagy 2006; 2: 138\u2013139.","journal-title":"Autophagy"},{"key":"BFcddis2013465_CR21","doi-asserted-by":"publisher","first-page":"2303","DOI":"10.1158\/0008-5472.CAN-04-3448","volume":"65","author":"WC Huang","year":"2005","unstructured":"Huang WC, Xie Z, Konaka H, Sodek J, Zhau HE, Chung LWK . Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway. Cancer Res 2005; 65: 2303\u20132313.","journal-title":"Cancer Res"},{"key":"BFcddis2013465_CR22","doi-asserted-by":"publisher","first-page":"2608","DOI":"10.1016\/j.ejca.2013.03.002","volume":"49","author":"P Bendinelli","year":"2013","unstructured":"Bendinelli P, Maroni P, Matteucci E, Luzzati A, Perrucchini G, Desiderio MA . Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer. Eur J Cancer 2013; 49: 2608\u20132618.","journal-title":"Eur J Cancer"},{"key":"BFcddis2013465_CR23","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s10549-010-1240-1","volume":"129","author":"P Maroni","year":"2011","unstructured":"Maroni P, Matteucci E, Luzzati A, Perrucchini G, Bendinelli P, Desiderio MA . Nuclear co-localization and functional interaction of COX-2 and HIF-1\u03b1 characterize bone metastasis of human breast carcinoma. Breast Cancer Res Treat 2011; 129: 433\u2013450.","journal-title":"Breast Cancer Res Treat"},{"key":"BFcddis2013465_CR24","doi-asserted-by":"publisher","first-page":"2287","DOI":"10.4161\/cc.10.14.16532","volume":"10","author":"KA Whelan","year":"2011","unstructured":"Whelan KA, Reginato MJ . Surviving without oxygen: hypoxia regulation of mammary morphogenesis and anoikis. Cell Cycle 2011; 10: 2287\u20132294.","journal-title":"Cell Cycle"},{"key":"BFcddis2013465_CR25","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/j.molmed.2013.04.005","volume":"19","author":"H Maes","year":"2013","unstructured":"Maes H, Rubio N, Garg AD, Agostinis P . Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol Med 2013; 19: 428\u2013446.","journal-title":"Trends Mol Med"},{"key":"BFcddis2013465_CR26","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1158\/1541-7786.MCR-08-0548","volume":"7","author":"P Bendinelli","year":"2009","unstructured":"Bendinelli P, Matteucci E, Maroni P, Desiderio MA . NF-kB activation, dependent on acetylation\/deacetylation, contributes to HIF-1 activity and migration of bone metastatic breast carcinoma cells. Mol Cancer Res 2009; 7: 1328\u20131341.","journal-title":"Mol Cancer Res"},{"key":"BFcddis2013465_CR27","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1007\/s00018-007-7050-x","volume":"64","author":"MA Desiderio","year":"2007","unstructured":"Desiderio MA . Hepatocyte growth factor in invasive growth of carcinomas. Cell Mol Life Sci 2007; 64: 1341\u20131354.","journal-title":"Cell Mol Life Sci"},{"key":"BFcddis2013465_CR28","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1002\/path.3000","volume":"226","author":"ML Taddei","year":"2012","unstructured":"Taddei ML, Giannoni E, Fiaschi T, Chiarugi P . Anoikis: an emerging hallmark in health and diseases. J Pathol 2012; 226: 380\u2013393.","journal-title":"J Pathol"},{"key":"BFcddis2013465_CR29","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1016\/j.bone.2011.08.023","volume":"49","author":"K Chen","year":"2011","unstructured":"Chen K, Perez-Stable C, D\u2019Ippolito G, Schiller PC, Roos BA, Howard GA . Human bone marrow-derived stem cell proliferation is inhibited by hepatocyte growth factor via increasing the cell cycle inhibitors p53, p21 and p27. Bone 2011; 49: 1194\u20131204.","journal-title":"Bone"},{"key":"BFcddis2013465_CR30","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1002\/bies.201100025","volume":"33","author":"AM Soto","year":"2011","unstructured":"Soto AM, Sonnenschein C . The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory. Bioassays 2011; 33: 332\u2013340.","journal-title":"Bioassays"},{"key":"BFcddis2013465_CR31","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.cell.2011.09.024","volume":"147","author":"S Valastyan","year":"2011","unstructured":"Valastyan S, Weinberg RA . Tumor metastasis: molecular insights and evolving paradigms. Cell 2011; 147: 275\u2013292.","journal-title":"Cell"},{"key":"BFcddis2013465_CR32","doi-asserted-by":"publisher","first-page":"888","DOI":"10.3390\/ijms14010888","volume":"14","author":"S Mizuno","year":"2013","unstructured":"Mizuno S, Nakamura T . HGF-MET cascade, a key target for inhibiting cancer metastasis: the impact of NK4 discovery on cancer biology and therapeutics. Int J Mol Sci 2013; 14: 888\u2013919.","journal-title":"Int J Mol Sci"},{"key":"BFcddis2013465_CR33","doi-asserted-by":"publisher","first-page":"3835","DOI":"10.1016\/j.bbagen.2013.03.009","volume":"1830","author":"L Wei","year":"2013","unstructured":"Wei L, Dai Q, Zhou Y, Zou M, Li Z, Lu N et al. Oroxylin A sensitizes non-small cell lung cancer cells to anoikis via glucose-deprivation-like mechanisms: c-Src and hexokinase II. Biochim Biophys Acta 2013; 1830: 3835\u20133845.","journal-title":"Biochim Biophys Acta"},{"issue":"15","key":"BFcddis2013465_CR34","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1089\/ars.2012.5028","volume":"19","author":"John F. Woolley","year":"2013","unstructured":"Woolley JF, Corcoran A, Groeger G, Landry WD, Cotter TG . Redox-regulated growth factor survival signaling. Antioxid Redox Signal 2013 doi:10.1089\/ars.2012.5028.","journal-title":"Antioxidants & Redox Signaling"},{"key":"BFcddis2013465_CR35","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1074\/jbc.M505546200","volume":"281","author":"X-J Qi","year":"2006","unstructured":"Qi X-J, Wildey GM, Howe PH . Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J Biol Chem 2006; 281: 813\u2013823.","journal-title":"J Biol Chem"},{"key":"BFcddis2013465_CR36","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1016\/j.bbamcr.2012.06.017","volume":"1823","author":"SM Ruppert","year":"2012","unstructured":"Ruppert SM, Li W, Zhang G, Carlson AL, Limaye A, Durum SK et al. The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes. Biochim Biophys Acta 2012; 1823: 1877\u20131893.","journal-title":"Biochim Biophys Acta"},{"key":"BFcddis2013465_CR37","doi-asserted-by":"publisher","first-page":"2074","DOI":"10.1038\/onc.2009.77","volume":"28","author":"E Giannoni","year":"2009","unstructured":"Giannoni E, Fiaschi T, Ramponi G, Chiarugi P . Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals. Oncogene 2009; 28: 2074\u20132086.","journal-title":"Oncogene"},{"key":"BFcddis2013465_CR38","doi-asserted-by":"publisher","first-page":"3829","DOI":"10.1091\/mbc.e10-04-0353","volume":"21","author":"KA Whelan","year":"2010","unstructured":"Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ et al. Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis. Mol Biol Cell 2010; 21: 3829\u20133837.","journal-title":"Mol Biol Cell"},{"key":"BFcddis2013465_CR39","doi-asserted-by":"publisher","first-page":"2358","DOI":"10.1073\/pnas.0712176105","volume":"105","author":"M Emaduddin","year":"2008","unstructured":"Emaduddin M, Bicknell DC, Bodmer WF, Feller SM . Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci USA 2008; 105: 2358\u20132362.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcddis2013465_CR40","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1158\/1541-7786.MCR-09-0511","volume":"8","author":"JI Kim","year":"2010","unstructured":"Kim JI, Lakshmikanthan V, Frilot N, Daaka Y . Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalosome. Mol Cancer Res 2010; 8: 569\u2013577.","journal-title":"Mol Cancer Res"},{"key":"BFcddis2013465_CR41","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1124\/jpet.106.102004","volume":"318","author":"N Rucci","year":"2006","unstructured":"Rucci N, Recchia I, Angelucci A, Alamanou M, Del Fattore A, Fortunati D et al. Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastasis and increases survival in mice: implications for therapy. J Pharmacol Exp Ther 2006; 318: 161\u2013172.","journal-title":"J Pharmacol Exp Ther"},{"key":"BFcddis2013465_CR42","doi-asserted-by":"publisher","first-page":"979","DOI":"10.4161\/auto.20232","volume":"8","author":"YL Hu","year":"2012","unstructured":"Hu YL, Jahangiri A, De Lay M, Aghi MK . Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy. Autophagy 2012; 8: 979\u2013981.","journal-title":"Autophagy"},{"key":"BFcddis2013465_CR43","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3389\/fnmol.2011.00051","volume":"4","author":"J Karar","year":"2011","unstructured":"Karar J, Maity A . PI3K\/AKT\/mTOR pathway in angiogenesis. Front Mol Neurosci 2011; 4: 51.","journal-title":"Front Mol Neurosci"},{"key":"BFcddis2013465_CR44","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1007\/s00259-003-1441-5","volume":"31","author":"V Ponomarev","year":"2004","unstructured":"Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T et al. A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur J Nucl Med Mol Imag 2004; 31: 740\u2013751.","journal-title":"Eur J Nucl Med Mol Imag"},{"key":"BFcddis2013465_CR45","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s10585-011-9436-2","volume":"29","author":"L Rice","year":"2012","unstructured":"Rice L, Lepler S, Pampo C, Siemann DW . Impact of the SRC inhibitor dasatinib on the metastatic phenotype of human prostate cancer cells. Clin Exp Metast 2012; 29: 133\u2013142.","journal-title":"Clin Exp Metast"},{"key":"BFcddis2013465_CR46","doi-asserted-by":"publisher","first-page":"3983","DOI":"10.3748\/wjg.v12.i25.3983","volume":"12","author":"JZ Jie","year":"2006","unstructured":"Jie JZ, Wang JW, Qu JG, Wang W, Hung T . Effects of adenoviral-mediated gene transduction of NK4 on proliferation, movement, and invasion of human colonic LS174T cancer cells in vitro. World J Gastroenterol 2006; 12: 3983\u20133988.","journal-title":"World J Gastroenterol"},{"key":"BFcddis2013465_CR47","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1046\/j.1365-2184.2001.00198.x","volume":"34","author":"AJ Bretland","year":"2001","unstructured":"Bretland AJ, Lawry J, Sharrard RM . A study of death by anoikis in cultured epithelial cells. Cell Prolif 2001; 34: 199\u2013210.","journal-title":"Cell Prolif"},{"key":"BFcddis2013465_CR48","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1002\/1097-4652(2000)9999:9999<000::AID-JCP1033>3.0.CO;2-8","volume":"186","author":"E Matteucci","year":"2001","unstructured":"Matteucci E, Castoldi R, Desiderio MA . Hepatocyte growth factor induces pro-apoptotic genes in HepG2 hepatoma but not in B16-F1 melanoma cells. J Cell Physiol 2001; 186: 387\u2013396.","journal-title":"J Cell Physiol"},{"key":"BFcddis2013465_CR49","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1006\/mthe.2002.0533","volume":"5","author":"M Maemondo","year":"2002","unstructured":"Maemondo M, Narumi K, Saijo Y, Usui K, Tahara M, Tazawa R et al. Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy. Mol Ther 2002; 5: 177\u2013185.","journal-title":"Mol Ther"}],"updated-by":[{"DOI":"10.1038\/s41419-022-04991-7","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"record-id":"37622"},{"DOI":"10.1038\/s41419-022-04991-7","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000}}],"container-title":["Cell Death &amp; Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/cddis2013465.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/cddis2013465","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/cddis2013465.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T23:32:15Z","timestamp":1672961535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cddis2013465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,16]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,1]]}},"alternative-id":["BFcddis2013465"],"URL":"https:\/\/doi.org\/10.1038\/cddis.2013.465","relation":{},"ISSN":["2041-4889"],"issn-type":[{"value":"2041-4889","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,16]]},"assertion":[{"value":"12 September 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 January 2014","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2022","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article has been retracted. Please see the Retraction Notice for more detail:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1038\/s41419-022-04991-7","URL":"https:\/\/doi.org\/10.1038\/s41419-022-04991-7","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}