{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T10:52:56Z","timestamp":1789901576603,"version":"4.0.1"},"reference-count":44,"publisher":"Wiley","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pharmacol Ther"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1038\/clpt.2009.185","type":"journal-article","created":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T15:57:49Z","timestamp":1257350269000},"page":"74-86","source":"Crossref","is-referenced-by-count":63,"title":["A Pharmacovigilance Program From Laboratory Signals for the Detection and Reporting of Serious Adverse Drug Reactions in Hospitalized Patients"],"prefix":"10.1111","volume":"87","author":[{"given":"E","family":"Ramirez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A J","family":"Carcas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A M","family":"Borobia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S H","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Pi\u00f1ana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Fudio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Frias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,11,4]]},"reference":[{"key":"clpt2009185-bib1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.155.18.1949"},{"key":"clpt2009185-bib2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.329.7456.15"},{"key":"clpt2009185-bib3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.277.4.301"},{"key":"clpt2009185-bib4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.15.1200"},{"key":"clpt2009185-bib5","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1056\/NEJM199102073240605","volume":"324","author":"Leape L.L","year":"1991","journal-title":"N. Engl. J. Med"},{"key":"clpt2009185-bib6","first-page":"2229","volume":"49","author":"Hartwig S.C","year":"1992","journal-title":"Am. J. Hosp. Pharm"},{"key":"clpt2009185-bib7","unstructured":""},{"key":"clpt2009185-bib8","doi-asserted-by":"publisher","DOI":"10.1177\/089719008900200403"},{"key":"clpt2009185-bib9","unstructured":""},{"key":"clpt2009185-bib10","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1177\/106002809402800417","volume":"28","author":"Evans R.S","year":"1994","journal-title":"Ann. Pharmacother"},{"key":"clpt2009185-bib11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1996.tb00004.x"},{"key":"clpt2009185-bib12","doi-asserted-by":"publisher","DOI":"10.1016\/S1386-5056(99)00020-9"},{"key":"clpt2009185-bib13","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050571"},{"key":"clpt2009185-bib14","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-006-0242-8"},{"key":"clpt2009185-bib15","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.2000.00282.x"},{"key":"clpt2009185-bib16","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200022020-00007"},{"key":"clpt2009185-bib17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.277.4.307"},{"key":"clpt2009185-bib18","unstructured":""},{"key":"clpt2009185-bib19","unstructured":""},{"key":"clpt2009185-bib20","unstructured":""},{"key":"clpt2009185-bib21","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/ajhp\/52.4.417","volume":"52","year":"1995","journal-title":"Am. J. Health Syst. Pharm"},{"key":"clpt2009185-bib22","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(84)90106-4"},{"key":"clpt2009185-bib23","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1001\/jama.1986.03380130077032","volume":"256","year":"1986","journal-title":"JAMA"},{"key":"clpt2009185-bib24","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastro.2005.05.006"},{"key":"clpt2009185-bib25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra066469"},{"key":"clpt2009185-bib26","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp052967"},{"key":"clpt2009185-bib27","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp066837"},{"key":"clpt2009185-bib28","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005253422107"},{"key":"clpt2009185-bib29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.21.2585"},{"key":"clpt2009185-bib30","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.2.254"},{"key":"clpt2009185-bib31","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.9.1107"},{"key":"clpt2009185-bib32","first-page":"32","volume":"53","author":"Miller M","year":"1998","journal-title":"Geriatrics"},{"key":"clpt2009185-bib33","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.15.1858"},{"key":"clpt2009185-bib34","doi-asserted-by":"publisher","DOI":"10.1136\/qshc.2002.002972"},{"key":"clpt2009185-bib35","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20489"},{"key":"clpt2009185-bib36","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2008.03.004"},{"key":"clpt2009185-bib37","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a2286"},{"key":"clpt2009185-bib38","doi-asserted-by":"publisher","DOI":"10.2217\/14622416.7.4.633"},{"key":"clpt2009185-bib39","unstructured":""},{"key":"clpt2009185-bib40","unstructured":""},{"key":"clpt2009185-bib41","first-page":"75","volume":"29","year":"1991","journal-title":"Int. J. Clin. Pharmacol. Ther. Toxicol"},{"key":"clpt2009185-bib42","unstructured":""},{"key":"clpt2009185-bib43","unstructured":""},{"key":"clpt2009185-bib44","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7407.115"}],"container-title":["Clinical Pharmacology & Therapeutics"],"original-title":[],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T13:15:28Z","timestamp":1699362928000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1038\/clpt.2009.185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,4]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,11,4]]},"published-print":{"date-parts":[[2010,1]]}},"alternative-id":["clpt2009185"],"URL":"https:\/\/doi.org\/10.1038\/clpt.2009.185","relation":{},"ISSN":["0009-9236","1532-6535"],"issn-type":[{"value":"0009-9236","type":"print"},{"value":"1532-6535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,4]]}}}