{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T02:07:52Z","timestamp":1783044472318,"version":"3.54.6"},"reference-count":15,"publisher":"Wiley","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pharmacol Ther"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1038\/clpt.2009.35","type":"journal-article","created":{"date-parts":[[2009,4,8]],"date-time":"2009-04-08T14:59:37Z","timestamp":1239202777000},"page":"44-48","source":"Crossref","is-referenced-by-count":103,"title":["Efficacy of 3,4-Diaminopyridine and Pyridostigmine in the Treatment of Lambert\u2013Eaton Myasthenic Syndrome: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study"],"prefix":"10.1111","volume":"86","author":[{"given":"PW","family":"Wirtz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JJ","family":"Verschuuren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JG","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ML","family":"de Kam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RC","family":"Schoemaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JGC","family":"van Hasselt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MJ","family":"Titulaer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"UR","family":"Tjaden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"den Hartigh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JMA","family":"van Gerven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,4,8]]},"reference":[{"key":"clpt200935-bib1","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1056\/NEJM198912073212303","volume":"321","author":"McEvoy K.M","year":"1989","journal-title":"N. Engl. J. Med"},{"key":"clpt200935-bib2","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1212\/WNL.54.3.603","volume":"54","author":"Sanders D.B","year":"2000","journal-title":"Neurology"},{"key":"clpt200935-bib3","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/BF00636797","volume":"18","author":"Aquilonius S.M","year":"1980","journal-title":"Eur. J. Clin. Pharmacol"},{"key":"clpt200935-bib4","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1136\/jnnp.44.12.1141","volume":"44","author":"Davison S.C","year":"1981","journal-title":"J. Neurol. Neurosurg. Psychiatr"},{"key":"clpt200935-bib5","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1212\/WNL.37.5.800","volume":"37","author":"Milner-Brown H.S","year":"1987","journal-title":"Neurology"},{"key":"clpt200935-bib6","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/jnnp.53.6.502","volume":"53","author":"Breyer-Pfaff U","year":"1990","journal-title":"J. Neurol. Neurosurg. Psychiatr"},{"key":"clpt200935-bib7","unstructured":""},{"key":"clpt200935-bib8","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/j.1600-0404.1993.tb04205.x","volume":"88","author":"Lundh H","year":"1993","journal-title":"Acta Neurol. Scand"},{"key":"clpt200935-bib9","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1212\/WNL.34.10.1324","volume":"34","author":"Lundh H","year":"1984","journal-title":"Neurology"},{"key":"clpt200935-bib10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0022-510X(96)00012-3","volume":"138","author":"Aisen M.L","year":"1996","journal-title":"J. Neurol. Sci"},{"key":"clpt200935-bib11","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1212\/WNL.47.6.1457","volume":"47","author":"Bever C.T","year":"1996","journal-title":"Neurology"},{"key":"clpt200935-bib12","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1002\/mus.1139","volume":"24","year":"2001","journal-title":"Muscle Nerve"},{"key":"clpt200935-bib13","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1002\/(SICI)1097-4598(199607)19:7<903::AID-MUS15>3.0.CO;2-J","volume":"19","author":"Oh S.J","year":"1996","journal-title":"Muscle Nerve"},{"key":"clpt200935-bib14","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/BF00313939","volume":"231","author":"van der Ploeg R.J","year":"1984","journal-title":"J. Neurol"},{"key":"clpt200935-bib15","unstructured":""}],"container-title":["Clinical Pharmacology &amp; Therapeutics"],"original-title":[],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T13:14:45Z","timestamp":1699362885000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1038\/clpt.2009.35"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,8]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,4,8]]},"published-print":{"date-parts":[[2009,7]]}},"alternative-id":["clpt200935"],"URL":"https:\/\/doi.org\/10.1038\/clpt.2009.35","relation":{},"ISSN":["0009-9236","1532-6535"],"issn-type":[{"value":"0009-9236","type":"print"},{"value":"1532-6535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,8]]}}}