{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T23:57:04Z","timestamp":1769731024494,"version":"3.49.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Mol Immunol"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1038\/cmi.2015.94","type":"journal-article","created":{"date-parts":[[2015,12,14]],"date-time":"2015-12-14T09:40:45Z","timestamp":1450086045000},"page":"1-2","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Viral immunology: reunion of the conjoined twins disciplines"],"prefix":"10.1038","volume":"13","author":[{"given":"Chi-Chiang","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,1,4]]},"reference":[{"key":"BFcmi201594_CR1","first-page":"76","volume-title":"Understanding Viruses","author":"Shors Teri","year":"2008","unstructured":"Teri Shors Understanding Viruses. Sudbury, MA: Jones & Bartlett Publishers, 2008: 76\u201377."},{"key":"BFcmi201594_CR2","first-page":"3","volume-title":"Topley & Wilson's Microbiology and Microbial Infections","author":"M Sussman","year":"1998","unstructured":"Sussman M, Topley WWC, Wilson GK, Collier LH, Balows A . Topley & Wilson's Microbiology and Microbial Infections. London: Arnold, 1998: 3."},{"key":"BFcmi201594_CR3","volume-title":"Oxford Dictionary of National Biography","author":"D Baxby","year":"2014","unstructured":"Baxby D . \u201cJenner, Edward (1749\u20131823)\u201d. Oxford Dictionary of National Biography. Oxford University Press. Retrieved 14 February 2014."},{"key":"BFcmi201594_CR4","first-page":"11","volume":"12","author":"MT Wong","year":"2015","unstructured":"Wong MT, Chen SS-L . Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection. Cell Mol Immunol 2015; 12: 11\u201335.","journal-title":"Cell Mol Immunol"},{"key":"BFcmi201594_CR5","first-page":"3","volume":"12","author":"Q Liu","year":"2015","unstructured":"Liu Q, Zhou YH, Yang ZQ . The cytokine storm of severe influenza and development of immunomodulatory therapy. Cell Mol Immunol 2015; 12: 3\u201310.","journal-title":"Cell Mol Immunol"},{"key":"BFcmi201594_CR6","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1038\/nature06246","volume":"449","author":"R Medzhitov","year":"2007","unstructured":"Medzhitov R . Recognition of microorganisms and activation of the immune response. Nature 2007; 449: 819\u2013826.","journal-title":"Nature"},{"key":"BFcmi201594_CR7","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1172\/JCI34431","volume":"118","author":"GM Barton","year":"2008","unstructured":"Barton GM . A calculated response: control of inflammation by the innate immune system. J Clin Invest 2008; 118: 413\u2013420.","journal-title":"J Clin Invest"},{"key":"BFcmi201594_CR8","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1038\/cmi.2014.66","volume":"12","author":"HB Liang","year":"2015","unstructured":"Liang HB, Lee M, Jin X, Guiding dengue vaccine development using knowledge gained from the success of the yellow fever vaccine. Cell Mol Immunol 2015; 12: 36\u201346.","journal-title":"Cell Mol Immunol"},{"key":"BFcmi201594_CR9","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1038\/nature12060","volume":"496","author":"S Bhatt","year":"2013","unstructured":"Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL et al. The global distribution and burden of dengue. Nature 2013; 496: 504\u2013507.","journal-title":"Nature"},{"key":"BFcmi201594_CR10","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S0065-3527(03)60006-0","volume":"60","author":"LD Kramer","year":"2003","unstructured":"Kramer LD, Ebel GD . Dynamics of flavivirus infection in mosquitoes. Adv Virus Res 2003; 60: 187\u2013232 .","journal-title":"Adv Virus Res"}],"container-title":["Cellular & Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/cmi201594.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cmi201594","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cmi201594.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:18:48Z","timestamp":1684415928000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cmi201594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["BFcmi201594"],"URL":"https:\/\/doi.org\/10.1038\/cmi.2015.94","relation":{},"ISSN":["1672-7681","2042-0226"],"issn-type":[{"value":"1672-7681","type":"print"},{"value":"2042-0226","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"5 October 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}