{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:08:41Z","timestamp":1791220121459,"version":"4.1.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,2,6]],"date-time":"2015-02-06T00:00:00Z","timestamp":1423180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Res"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1038\/cr.2015.15","type":"journal-article","created":{"date-parts":[[2015,2,6]],"date-time":"2015-02-06T11:35:46Z","timestamp":1423222546000},"page":"275-287","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":142,"title":["CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development"],"prefix":"10.1038","volume":"25","author":[{"given":"Tao","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiwen","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongting","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruirui","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pushuai","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongde","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane Y","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiyun","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,2,6]]},"reference":[{"key":"BFcr201515_CR1","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/j.cell.2011.08.039","volume":"146","author":"M Potente","year":"2011","unstructured":"Potente M, Gerhardt H, Carmeliet P . Basic and therapeutic aspects of angiogenesis. Cell 2011; 146:873\u2013887.","journal-title":"Cell"},{"key":"BFcr201515_CR2","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1146\/annurev-cellbio-092910-154002","volume":"27","author":"AS Chung","year":"2011","unstructured":"Chung AS, Ferrara N . Developmental and pathological angiogenesis. Annu Rev Cell Dev Biol 2011; 27:563\u2013584.","journal-title":"Annu Rev Cell Dev Biol"},{"key":"BFcr201515_CR3","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1038\/nature10144","volume":"473","author":"P Carmeliet","year":"2011","unstructured":"Carmeliet P, Jain RK . Molecular mechanisms and clinical applications of angiogenesis. Nature 2011; 473:298\u2013307.","journal-title":"Nature"},{"key":"BFcr201515_CR4","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1146\/annurev.cellbio.093008.093324","volume":"26","author":"M Melani","year":"2010","unstructured":"Melani M, Weinstein BM . Common factors regulating patterning of the nervous and vascular systems. Annu Rev Cell Dev Biol 2010; 26:639\u2013665.","journal-title":"Annu Rev Cell Dev Biol"},{"key":"BFcr201515_CR5","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.ceb.2012.02.002","volume":"24","author":"A Eichmann","year":"2012","unstructured":"Eichmann A, Simons M . VEGF signaling inside vascular endothelial cells and beyond. Curr Opin Cell Biol 2012; 24:188\u2013193.","journal-title":"Curr Opin Cell Biol"},{"key":"BFcr201515_CR6","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1038\/ncomms1977","volume":"3","author":"MJ Cudmore","year":"2012","unstructured":"Cudmore MJ, Hewett PW, Ahmad S, et al. The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis. Nat Commun 2012; 3:972.","journal-title":"Nat Commun"},{"key":"BFcr201515_CR7","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1038\/nature03080","volume":"432","author":"X Lu","year":"2004","unstructured":"Lu X, Le Noble F, Yuan L, et al. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 2004; 432:179\u2013186.","journal-title":"Nature"},{"key":"BFcr201515_CR8","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1126\/science.1124704","volume":"313","author":"BD Wilson","year":"2006","unstructured":"Wilson BD, Ii M, Park KW, et al. Netrins promote developmental and therapeutic angiogenesis. Science 2006; 313:640\u2013644.","journal-title":"Science"},{"key":"BFcr201515_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S1535-6108(03)00166-1","volume":"4","author":"ZJ Liu","year":"2003","unstructured":"Liu ZJ, Herlyn M . Slit-Robo: neuronal guides signal in tumor angiogenesis. Cancer Cell 2003; 4:1\u20132.","journal-title":"Cancer Cell"},{"key":"BFcr201515_CR10","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1038\/nature08995","volume":"465","author":"S Sawamiphak","year":"2010","unstructured":"Sawamiphak S, Seidel S, Essmann CL, et al. Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 2010; 465:487\u2013491.","journal-title":"Nature"},{"key":"BFcr201515_CR11","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1038\/nature09002","volume":"465","author":"Y Wang","year":"2010","unstructured":"Wang Y, Nakayama M, Pitulescu ME, et al. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature 2010; 465:483\u2013486.","journal-title":"Nature"},{"key":"BFcr201515_CR12","doi-asserted-by":"publisher","first-page":"9017","DOI":"10.1073\/pnas.0508825103","volume":"103","author":"JR Basile","year":"2006","unstructured":"Basile JR, Castilho RM, Williams VP, Gutkind JS . Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis. Proc Natl Acad Sci USA 2006; 103:9017\u20139022.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201515_CR13","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/0092-8674(94)90420-0","volume":"78","author":"T Serafini","year":"1994","unstructured":"Serafini T, Kennedy TE, Galko MJ, Mirzayan C, Jessell TM, Tessier-Lavigne M . The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 1994; 78:409\u2013424.","journal-title":"Cell"},{"key":"BFcr201515_CR14","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1016\/0092-8674(95)90083-7","volume":"81","author":"SA Colamarino","year":"1995","unstructured":"Colamarino SA, Tessier-Lavigne M . The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. Cell 1995; 81:621\u2013629.","journal-title":"Cell"},{"key":"BFcr201515_CR15","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/S0092-8674(00)81795-X","volume":"87","author":"T Serafini","year":"1996","unstructured":"Serafini T, Colamarino SA, Leonardo ED, et al. Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell 1996; 87:1001\u20131014.","journal-title":"Cell"},{"key":"BFcr201515_CR16","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/S0092-8674(00)81336-7","volume":"87","author":"K KeinoMasu","year":"1996","unstructured":"KeinoMasu K, Masu M, Hinck L, et al. Deleted in colorectal cancer (DCC) encodes a netrin receptor. Cell 1996; 87:175\u2013185.","journal-title":"Cell"},{"key":"BFcr201515_CR17","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/S0955-0674(98)80036-7","volume":"10","author":"JG Culotti","year":"1998","unstructured":"Culotti JG, Merz DC . DCC and netrins. Curr Opin Cell Biol 1998; 10:609\u2013613.","journal-title":"Curr Opin Cell Biol"},{"key":"BFcr201515_CR18","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1038\/386833a0","volume":"386","author":"ED Leonardo","year":"1997","unstructured":"Leonardo ED, Hinck L, Masu M, Keino-Masu K, Ackerman SL, Tessier-Lavigne M . Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors. Nature 1997; 386:833\u2013838.","journal-title":"Nature"},{"key":"BFcr201515_CR19","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/S0092-8674(00)80804-1","volume":"97","author":"KS Hong","year":"1999","unstructured":"Hong KS, Hinck L, Nishiyama M, Poo MM, Tessier-Lavigne M, Stein E . A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell 1999; 97:927\u2013941.","journal-title":"Cell"},{"key":"BFcr201515_CR20","doi-asserted-by":"publisher","first-page":"16210","DOI":"10.1073\/pnas.0405984101","volume":"101","author":"KW Park","year":"2004","unstructured":"Park KW, Crouse D, Lee M, et al. The axonal attractant Netrin-1 is an angiogenic factor. Proc Natl Acad Sci USA 2004; 101:16210\u201316215.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201515_CR21","doi-asserted-by":"publisher","first-page":"2433","DOI":"10.1101\/gad.437807","volume":"21","author":"B Larrivee","year":"2007","unstructured":"Larrivee B, Freitas C, Trombe M, et al. Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. Genes Dev 2007; 21:2433\u20132447.","journal-title":"Genes Dev"},{"key":"BFcr201515_CR22","doi-asserted-by":"publisher","first-page":"9891","DOI":"10.1073\/pnas.86.24.9891","volume":"86","author":"JM Lehmann","year":"1989","unstructured":"Lehmann JM, Riethmuller G, Johnson JP . Muc18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc Natl Acad Sci USA 1989; 86:9891\u20139895.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201515_CR23","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1016\/0896-6273(94)90338-7","volume":"12","author":"E Taira","year":"1994","unstructured":"Taira E, Takaha N, Taniura H, Kim CH, Miki N . Molecular cloning and functional expression of gicerin, a novel cell adhesion molecule that binds to neurite outgrowth factor. Neuron 1994; 12:861\u2013872.","journal-title":"Neuron"},{"key":"BFcr201515_CR24","first-page":"130","volume":"1795","author":"A Ouhtit","year":"2009","unstructured":"Ouhtit A, Gaur RL, Abd Elmageed ZY, et al. Towards understanding the mode of action of the multifaceted cell adhesion receptor CD146. Biochim Biophys Acta 2009; 1795:130\u2013136.","journal-title":"Biochim Biophys Acta"},{"key":"BFcr201515_CR25","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.canlet.2012.11.049","volume":"330","author":"Z Wang","year":"2013","unstructured":"Wang Z, Yan X . CD146, a multi-functional molecule beyond adhesion. Cancer Lett 2013; 330:150\u2013162.","journal-title":"Cancer Lett"},{"key":"BFcr201515_CR26","doi-asserted-by":"publisher","first-page":"2803","DOI":"10.1038\/ncomms3803","volume":"4","author":"Z Ye","year":"2013","unstructured":"Ye Z, Zhang C, Tu T, et al. Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension. Nat Commun 2013; 4:2803.","journal-title":"Nat Commun"},{"key":"BFcr201515_CR27","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1038\/sj.cr.7310039","volume":"16","author":"YY Kang","year":"2006","unstructured":"Kang YY, Wang FC, Feng J, Yang DL, Yang X, Yan XY . Knockdown of CD146 reduces the migration and proliferation of human endothelial cells. Cell Res 2006; 16:313\u2013318.","journal-title":"Cell Res"},{"key":"BFcr201515_CR28","doi-asserted-by":"publisher","first-page":"2163","DOI":"10.1016\/j.biocel.2009.03.014","volume":"41","author":"CG Zheng","year":"2009","unstructured":"Zheng CG, Qiu YJ, Zeng QQ, et al. Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization. Int J Biochem Cell Biol 2009; 41:2163\u20132172.","journal-title":"Int J Biochem Cell Biol"},{"key":"BFcr201515_CR29","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1182\/blood-2002-04-1004","volume":"102","author":"XY Yan","year":"2003","unstructured":"Yan XY, Lin Y, Yang DL, et al. A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth. Blood 2003; 102:184\u2013191.","journal-title":"Blood"},{"key":"BFcr201515_CR30","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1002\/dvdy.20220","volume":"232","author":"B Chan","year":"2005","unstructured":"Chan B, Sinha S, Cho D, Ramchandran R, Sukhatme VP . Critical roles of CD146 in zebrafish vascular development. Dev Dyn 2005; 232:232\u2013244.","journal-title":"Dev Dyn"},{"key":"BFcr201515_CR31","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1161\/CIRCRESAHA.109.213827","volume":"107","author":"A Kebir","year":"2010","unstructured":"Kebir A, Harhouri K, Guillet B, et al. CD146 short isoform increases the proangiogenic potential of endothelial progenitor cells in vitro and in vivo. Circ Res 2010; 107:66\u201375.","journal-title":"Circ Res"},{"key":"BFcr201515_CR32","doi-asserted-by":"publisher","first-page":"3843","DOI":"10.1182\/blood-2009-06-229591","volume":"115","author":"K Harhouri","year":"2010","unstructured":"Harhouri K, Kebir A, Guillet B, et al. Soluble CD146 displays angiogenic properties and promotes neovascularization in experimental hind-limb ischemia. Blood 2010; 115:3843\u20133851.","journal-title":"Blood"},{"key":"BFcr201515_CR33","doi-asserted-by":"publisher","first-page":"2872","DOI":"10.1158\/1535-7163.MCT-06-0260","volume":"5","author":"P Bu","year":"2006","unstructured":"Bu P, Gao L, Zhuang J, Feng J, Yang D, Yan X . Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kappaB activation. Mol Cancer Ther 2006; 5:2872\u20132878.","journal-title":"Mol Cancer Ther"},{"key":"BFcr201515_CR34","doi-asserted-by":"publisher","first-page":"2330","DOI":"10.1182\/blood-2012-01-406108","volume":"120","author":"T Jiang","year":"2012","unstructured":"Jiang T, Zhuang J, Duan H, et al. CD146 is a coreceptor for VEGFR-2 in tumor angiogenesis. Blood 2012; 120:2330\u20132339.","journal-title":"Blood"},{"key":"BFcr201515_CR35","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/S0092-8674(00)80590-5","volume":"96","author":"K Brose","year":"1999","unstructured":"Brose K, Bland KS, Wang KH, et al. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell 1999; 96:795\u2013806.","journal-title":"Cell"},{"key":"BFcr201515_CR36","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1089\/hyb.2008.0034","volume":"27","author":"Y Zhang","year":"2008","unstructured":"Zhang Y, Zheng C, Zhang J, et al. Generation and characterization of a panel of monoclonal antibodies against distinct epitopes of human CD146. Hybridoma (Larchmt) 2008; 27:345\u2013352.","journal-title":"Hybridoma (Larchmt)"},{"key":"BFcr201515_CR37","doi-asserted-by":"publisher","first-page":"743","DOI":"10.4161\/cbt.6.5.3976","volume":"6","author":"Y Yang","year":"2007","unstructured":"Yang Y, Zou L, Wang Y, Xu KS, Zhang JX, Zhang JH . Axon guidance cue Netrin-1 has dual function in angiogenesis. Cancer Biol Ther 2007; 6:743\u2013748.","journal-title":"Cancer Biol Ther"},{"key":"BFcr201515_CR38","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1126\/science.1255149","volume":"344","author":"K Xu","year":"2014","unstructured":"Xu K, Wu Z, Renier N, et al. Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science 2014; 344:1275\u20131279.","journal-title":"Science"},{"key":"BFcr201515_CR39","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s13238-014-0047-y","volume":"5","author":"Q Zeng","year":"2014","unstructured":"Zeng Q, Wu Z, Duan H, et al. Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice. Protein Cell 2014; 5:445\u2013456.","journal-title":"Protein Cell"},{"key":"BFcr201515_CR40","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1161\/CIRCRESAHA.108.188144","volume":"104","author":"B Larrivee","year":"2009","unstructured":"Larrivee B, Freitas C, Suchting S, Brunet I, Eichmann A . Guidance of vascular development: lessons from the nervous system. Circ Res 2009; 104:428\u2013441.","journal-title":"Circ Res"},{"key":"BFcr201515_CR41","doi-asserted-by":"publisher","first-page":"4850","DOI":"10.1073\/pnas.0709810105","volume":"105","author":"J Fitamant","year":"2008","unstructured":"Fitamant J, Guenebeaud C, Coissieux MM, et al. Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer. Proc Natl Acad Sci USA 2008; 105:4850\u20134855.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201515_CR42","doi-asserted-by":"publisher","first-page":"17146","DOI":"10.1073\/pnas.0901767106","volume":"106","author":"A Paradisi","year":"2009","unstructured":"Paradisi A, Maisse C, Coissieux MM, et al. Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression. Proc Natl Acad Sci USA 2009; 106:17146\u201317151.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201515_CR43","first-page":"415","volume":"31","author":"S Kaufmann","year":"2009","unstructured":"Kaufmann S, Kuphal S, Schubert T, Bosserhoff AK . Functional implication of Netrin expression in malignant melanoma. Cell Oncol 2009; 31:415\u2013422.","journal-title":"Cell Oncol"},{"key":"BFcr201515_CR44","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1038\/380439a0","volume":"380","author":"N Ferrara","year":"1996","unstructured":"Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996; 380:439\u2013442.","journal-title":"Nature"},{"key":"BFcr201515_CR45","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1038\/380435a0","volume":"380","author":"P Carmeliet","year":"1996","unstructured":"Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996; 380:435\u2013439.","journal-title":"Nature"},{"key":"BFcr201515_CR46","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1038\/376066a0","volume":"376","author":"GH Fong","year":"1995","unstructured":"Fong GH, Rossant J, Gertsenstein M, Breitman ML . Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995; 376:66\u201370.","journal-title":"Nature"},{"key":"BFcr201515_CR47","doi-asserted-by":"publisher","first-page":"2381","DOI":"10.1182\/blood-2013-01-479063","volume":"121","author":"J Kitajewski","year":"2013","unstructured":"Kitajewski J . Wnts heal by restraining angiogenesis. Blood 2013; 121:2381\u20132382.","journal-title":"Blood"},{"key":"BFcr201515_CR48","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1038\/nature10085","volume":"474","author":"JA Stefater","year":"2011","unstructured":"Stefater JA 3rd, Lewkowich I, Rao S, et al. Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature 2011; 474:511\u2013515.","journal-title":"Nature"},{"key":"BFcr201515_CR49","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","volume":"203","author":"CB Kimmel","year":"1995","unstructured":"Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF . Stages of embryonic development of the zebrafish. Dev Dyn 1995; 203:253\u2013310.","journal-title":"Dev Dyn"},{"key":"BFcr201515_CR50","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/nprot.2011.435","volume":"7","author":"M Baker","year":"2011","unstructured":"Baker M, Robinson SD, Lechertier T, et al. Use of the mouse aortic ring assay to study angiogenesis. Nat Protoc 2011; 7:89\u2013104.","journal-title":"Nat Protoc"},{"key":"BFcr201515_CR51","doi-asserted-by":"publisher","first-page":"12589","DOI":"10.1523\/JNEUROSCI.6518-11.2012","volume":"32","author":"CW Zhang","year":"2012","unstructured":"Zhang CW, Gao JX, Zhang HF, Sun L, Peng G . Robo2-Slit and Dcc-Netrin1 coordinate neuron axonal pathfinding within the embryonic axon tracts. J Neurosci 2012; 32:12589\u201312602.","journal-title":"J Neurosci"},{"key":"BFcr201515_CR52","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1161\/CIRCRESAHA.108.179713","volume":"103","author":"F Liu","year":"2008","unstructured":"Liu F, Patient R . Genome-wide analysis of the zebrafish ETS family identifies three genes required for hemangioblast differentiation or angiogenesis. Circ Res 2008; 103:1147\u20131154.","journal-title":"Circ Res"}],"container-title":["Cell Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/cr201515.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cr201515","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cr201515.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:36:29Z","timestamp":1684416989000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cr201515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,6]]},"references-count":52,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["BFcr201515"],"URL":"https:\/\/doi.org\/10.1038\/cr.2015.15","relation":{},"ISSN":["1001-0602","1748-7838"],"issn-type":[{"value":"1001-0602","type":"print"},{"value":"1748-7838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,6]]},"assertion":[{"value":"15 December 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2015","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 January 2015","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2015","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}