{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T04:09:59Z","timestamp":1789445399017,"version":"build-2803163510"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T00:00:00Z","timestamp":1430179200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Res"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1038\/cr.2015.50","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T06:51:03Z","timestamp":1430203863000},"page":"785-800","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["In-cell infection: a novel pathway for Epstein-Barr virus infection mediated by cell-in-cell structures"],"prefix":"10.1038","volume":"25","author":[{"given":"Chao","family":"Ni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musheng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongjuan","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linquan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazhuo","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanyu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meifang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiawei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangkai","family":"Ning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manna","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jufang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinwen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,4,28]]},"reference":[{"key":"BFcr201550_CR1","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/S0966-842X(98)01309-2","volume":"6","author":"A Takada","year":"1998","unstructured":"Takada A, Kawaoka Y . Pathogenesis of Ebola virus infection: recent insights. Trends Microbiol 1998; 6:258\u2013259.","journal-title":"Trends Microbiol"},{"key":"BFcr201550_CR2","doi-asserted-by":"publisher","first-page":"591","DOI":"10.4049\/jimmunol.175.1.591","volume":"175","author":"H Chen","year":"2005","unstructured":"Chen H, Hou J, Jiang X, et al. Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals. J Immunol 2005; 175:591\u2013598.","journal-title":"J Immunol"},{"key":"BFcr201550_CR3","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1126\/science.8493571","volume":"260","author":"RA Weiss","year":"1993","unstructured":"Weiss RA . How does HIV cause AIDS? Science 1993; 260:1273\u20131279.","journal-title":"Science"},{"key":"BFcr201550_CR4","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1073\/pnas.98.4.1841","volume":"98","author":"H Tang","year":"2001","unstructured":"Tang H, McLachlan A . Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism. Proc Natl Acad Sci USA 2001; 98:1841\u20131846.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201550_CR5","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/S0140-6736(13)60022-7","volume":"382","author":"EJ Crosbie","year":"2013","unstructured":"Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC . Human papillomavirus and cervical cancer. Lancet 2013; 382:889\u2013899.","journal-title":"Lancet"},{"key":"BFcr201550_CR6","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1038\/2281053a0","volume":"228","author":"P Gunv\u00e9n","year":"1970","unstructured":"Gunv\u00e9n P, Klein G, Henle G, Henle W, Clifford P, Clifford P . Epstein \u2014 Barr virus in Burkitt's lymphoma and nasopharyngeal carcinoma: antibodies to EBV associated membrane and viral capsid antigens in Burkitt lymphoma patients. Nature 1970; 228:1053\u20131056.","journal-title":"Nature"},{"key":"BFcr201550_CR7","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1016\/S0140-6736(94)90217-8","volume":"343","author":"M Senba","year":"1994","unstructured":"Senba M, Zhong X, Senba M, Itakura H . EBV and nasopharyngeal carcinoma. Lancet 1994; 343:1104.","journal-title":"Lancet"},{"key":"BFcr201550_CR8","first-page":"34","volume":"3","author":"M Nomaguchi","year":"2012","unstructured":"Nomaguchi M, Fujita M, Miyazaki Y, Adachi A . Viral Tropism. Front Microbiol 2012; 3:34.","journal-title":"Front Microbiol"},{"key":"BFcr201550_CR9","first-page":"447","volume":"135","author":"CA Mims","year":"1989","unstructured":"Mims CA . The pathogenetic basis of viral tropism. Am J Pathol 1989; 135:447\u2013455.","journal-title":"Am J Pathol"},{"key":"BFcr201550_CR10","doi-asserted-by":"publisher","first-page":"15036","DOI":"10.1073\/pnas.232381299","volume":"99","author":"B Neuhierl","year":"2002","unstructured":"Neuhierl B, Feederle R, Hammerschmidt W, Delecluse HJ . Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection. Proc Natl Acad Sci USA 2002; 99:15036\u201315041.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201550_CR11","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.2353\/ajpath.2007.070695","volume":"171","author":"KG Mansfield","year":"2007","unstructured":"Mansfield KG . Viral tropism and the pathogenesis of influenza in the mammalian host. Am J Pathol 2007; 171:1089\u20131092.","journal-title":"Am J Pathol"},{"key":"BFcr201550_CR12","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1002\/jlb.49.5.499","volume":"49","author":"MP Moyer","year":"1991","unstructured":"Moyer MP, Gendelman HE . HIV replication and persistence in human gastrointestinal cells cultured in vitro. J Leukoc Biol 1991; 49:499\u2013504.","journal-title":"J Leukoc Biol"},{"key":"BFcr201550_CR13","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s11904-009-0004-1","volume":"6","author":"F Hladik","year":"2009","unstructured":"Hladik F, Hope TJ . HIV infection of the genital mucosa in women. Curr HIV\/AIDS Rep 2009; 6:20\u201328.","journal-title":"Curr HIV\/AIDS Rep"},{"key":"BFcr201550_CR14","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1038\/79331","volume":"18","author":"M Ronemus","year":"2000","unstructured":"Ronemus M . Shuffling viral tropism. Nat Biotechnol 2000; 18:913.","journal-title":"Nat Biotechnol"},{"key":"BFcr201550_CR15","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1038\/nri2623","volume":"9","author":"G McFadden","year":"2009","unstructured":"McFadden G, Mohamed MR, Rahman MM, Bartee E . Cytokine determinants of viral tropism. Nat Rev Immunol 2009; 9:645\u2013655.","journal-title":"Nat Rev Immunol"},{"key":"BFcr201550_CR16","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1056\/NEJM198405103101905","volume":"310","author":"JW Sixbey","year":"1984","unstructured":"Sixbey JW, Nedrud JG, Raab-Traub N, Hanes RA, Pagano JS . Epstein-Barr virus replication in oropharyngeal epithelial cells. N Engl J Med 1984; 310:1225\u20131230.","journal-title":"N Engl J Med"},{"key":"BFcr201550_CR17","doi-asserted-by":"publisher","first-page":"7825","DOI":"10.1128\/JVI.00445-07","volume":"81","author":"M Lindsey","year":"2007","unstructured":"Lindsey M, Hutt-Fletcher LM . Epstein-Barr virus entry. J Virol 2007; 81:7825\u20137832.","journal-title":"J Virol"},{"key":"BFcr201550_CR18","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1126\/science.1252786","volume":"343","author":"PM Lieberman","year":"2014","unstructured":"Lieberman PM . Virology. Epstein-Barr virus turns 50. Science 2014; 343:1323\u20131325.","journal-title":"Science"},{"key":"BFcr201550_CR19","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1128\/JVI.61.5.1416-1420.1987","volume":"61","author":"GR Nemerow","year":"1987","unstructured":"Nemerow GR, Mold C, Schwend VK, Tollefson V, Cooper NR . Identification of gp350 as the viral glycoprotein mediating attachment of Epstein-Barr virus (EBV) to the EBV\/C3d receptor of B cells: sequence homology of gp350 and C3 complement fragment C3d. J Virol 1987; 61:1416\u20131420.","journal-title":"J Virol"},{"key":"BFcr201550_CR20","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/0092-8674(89)90240-7","volume":"56","author":"GR Nemerow","year":"1989","unstructured":"Nemerow GR, Houghten RA, Moore MD, Cooper NR . Identification of an epitope in the major envelope protein of Epstein-Barr virus that mediates viral binding to the B lymphocyte EBV receptor (CR2). Cell 1989; 56:369\u2013377.","journal-title":"Cell"},{"key":"BFcr201550_CR21","doi-asserted-by":"crossref","first-page":"4121","DOI":"10.1128\/JVI.63.10.4121-4128.1989","volume":"63","author":"M Billaud","year":"1989","unstructured":"Billaud M, Busson P, Huang D, et al. Epstein-Barr virus (EBV)-containing nasopharyngeal carcinoma cells express the B-cell activation antigen blast2\/CD23 and low levels of the EBV receptor CR2. J Virol 1989; 63:4121\u20134128.","journal-title":"J Virol"},{"key":"BFcr201550_CR22","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1128\/JVI.69.7.3987-3994.1995","volume":"69","author":"Q Li","year":"1995","unstructured":"Li Q, Turk SM, Hutt-Fletcher LM . The Epstein-Barr virus (EBV) BZLF2 gene product associates with the gH and gL homologs of EBV and carries an epitope critical to infection of B cells but not of epithelial cells. J Virol 1995; 69:3987\u20133994.","journal-title":"J Virol"},{"key":"BFcr201550_CR23","doi-asserted-by":"publisher","first-page":"6324","DOI":"10.1128\/JVI.74.14.6324-6332.2000","volume":"74","author":"SJ Molesworth","year":"2000","unstructured":"Molesworth SJ, Lake CM, Borza CM, Turk SM, Hutt-Fletcher LM . Epstein-Barr virus gH is essential for penetration of B cells but also plays a role in attachment of virus to epithelial cells. J Virol 2000; 74:6324\u20136332.","journal-title":"J Virol"},{"key":"BFcr201550_CR24","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1128\/JVI.64.3.1348-1352.1990","volume":"64","author":"GR Nemerow","year":"1990","unstructured":"Nemerow GR, Mullen JJ 3rd, Dickson PW, Cooper NR . Soluble recombinant CR2 (CD21) inhibits Epstein-Barr virus infection. J Virol 1990; 64:1348\u20131352.","journal-title":"J Virol"},{"key":"BFcr201550_CR25","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1128\/JVI.72.1.158-163.1998","volume":"72","author":"X Wang","year":"1998","unstructured":"Wang X, Hutt-Fletcher LM . Epstein-Barr virus lacking glycoprotein gp42 can bind to B cells but is not able to infect. J Virol 1998; 72:158\u2013163.","journal-title":"J Virol"},{"key":"BFcr201550_CR26","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.virol.2012.10.039","volume":"436","author":"CL Rowe","year":"2013","unstructured":"Rowe CL, Connolly SA, Chen J, Jardetzky TS, Longnecker R . A soluble form of Epstein-Barr virus gH\/gL inhibits EBV-induced membrane fusion and does not function in fusion. Virology 2013; 436:118\u2013126.","journal-title":"Virology"},{"key":"BFcr201550_CR27","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/310099a0","volume":"310","author":"A Rickinson","year":"1984","unstructured":"Rickinson A . Epstein-Barr virus in epithelium. Nature 1984; 310:99\u2013100.","journal-title":"Nature"},{"key":"BFcr201550_CR28","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/nrc1452","volume":"4","author":"LS Young","year":"2004","unstructured":"Young LS, Rickinson AB . Epstein-Barr virus: 40 years on. Nat Rev Cancer 2004; 4:757\u2013768.","journal-title":"Nat Rev Cancer"},{"key":"BFcr201550_CR29","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.semcancer.2012.02.004","volume":"22","author":"SW Tsao","year":"2012","unstructured":"Tsao SW, Tsang CM, Pang PS, Zhang G, Chen H, Lo KW . The biology of EBV infection in human epithelial cells. Semin Cancer Biol 2012; 22:137\u2013143.","journal-title":"Semin Cancer Biol"},{"key":"BFcr201550_CR30","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1128\/JVI.72.5.4371-4378.1998","volume":"72","author":"S Imai","year":"1998","unstructured":"Imai S, Nishikawa J, Takada K . Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cells. J Virol 1998; 72:4371\u20134378.","journal-title":"J Virol"},{"key":"BFcr201550_CR31","doi-asserted-by":"publisher","first-page":"7065","DOI":"10.1073\/pnas.0510512103","volume":"103","author":"CD Shannon-Lowe","year":"2006","unstructured":"Shannon-Lowe CD, Neuhierl B, Baldwin G, Rickinson AB, Delecluse HJ . Resting B cells as a transfer vehicle for Epstein-Barr virus infection of epithelial cells. Proc Natl Acad Sci USA 2006; 103:7065\u20137070.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201550_CR32","doi-asserted-by":"publisher","first-page":"e1001338","DOI":"10.1371\/journal.ppat.1001338","volume":"7(5)","author":"C Shannon-Lowe","year":"2011","unstructured":"Shannon-Lowe C, Rowe M . Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection. PLoS Pathog 2011; 7(5):e1001338.","journal-title":"PLoS Pathog"},{"key":"BFcr201550_CR33","doi-asserted-by":"publisher","first-page":"16544","DOI":"10.1073\/pnas.1400818111","volume":"111","author":"RM Temple","year":"2014","unstructured":"Temple RM, Zhu J, Budgeon L, Christensen ND, Meyers C, Sample CE . Efficient replication of Epstein-Barr virus in stratified epithelium in vitro. Proc Natl Acad Sci USA 2014; 111:16544\u201316549.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201550_CR34","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1084\/jem.20030648","volume":"199","author":"C Jolly","year":"2004","unstructured":"Jolly C, Kashefi K, Hollinshead M, Sattentau QJ . HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse. J Exp Med 2004; 199:283\u2013293.","journal-title":"J Exp Med"},{"key":"BFcr201550_CR35","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1126\/science.1167525","volume":"323","author":"W H\u00fcbner","year":"2009","unstructured":"H\u00fcbner W, McNerney GP, Chen P, et al. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science 2009; 323:1743\u20131747.","journal-title":"Science"},{"key":"BFcr201550_CR36","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/nature10347","volume":"477","author":"A Sigal","year":"2011","unstructured":"Sigal A, Kim JT, Balazs AB, et al. Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy. Nature 2011; 477:95\u201398.","journal-title":"Nature"},{"key":"BFcr201550_CR37","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.chom.2012.07.005","volume":"12","author":"A Sigal","year":"2012","unstructured":"Sigal A, Baltimore D . As good as it gets? The problem of HIV persistence despite antiretroviral drugs. Cell Host Microbe 2012; 12:132\u2013138.","journal-title":"Cell Host Microbe"},{"key":"BFcr201550_CR38","doi-asserted-by":"publisher","first-page":"e59418","DOI":"10.1371\/journal.pone.0059418","volume":"8","author":"YH Chen","year":"2013","unstructured":"Chen YH, Wang S, He MF, et al. Prevalence of heterotypic tumor\/immune cell-in-cell structure in vitro and in vivo leading to formation of aneuploidy. PLoS One 2013; 8:e59418.","journal-title":"PLoS One"},{"key":"BFcr201550_CR39","doi-asserted-by":"publisher","first-page":"e630","DOI":"10.1038\/cddis.2013.147","volume":"4","author":"MF He","year":"2013","unstructured":"He MF, Wang S, Wang Y, Wang XN . Modeling cell-in-cell structure into its biological significance. Cell Death Dis 2013; 4:e630.","journal-title":"Cell Death Dis"},{"key":"BFcr201550_CR40","doi-asserted-by":"publisher","first-page":"e856","DOI":"10.1038\/cddis.2013.352","volume":"4","author":"S Wang","year":"2013","unstructured":"Wang S, He MF, Chen YH, et al. Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells. Cell Death Dis 2013; 4:e856.","journal-title":"Cell Death Dis"},{"key":"BFcr201550_CR41","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1038\/nrm2504","volume":"9","author":"M Overholtzer","year":"2008","unstructured":"Overholtzer M, Brugge JS . The cell biology of cell-in-cell structures. Nat Rev Mol Cell Biol 2008; 9:796\u2013809.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"BFcr201550_CR42","doi-asserted-by":"publisher","first-page":"e25988","DOI":"10.4161\/onci.25988","volume":"2","author":"Y Wang","year":"2013","unstructured":"Wang Y, Wang XN . Cell-in-cell: A virgin land of cell biology. Oncoimmunology 2013; 2:e25988.","journal-title":"Oncoimmunology"},{"key":"BFcr201550_CR43","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1038\/cr.2009.114","volume":"19","author":"S Wang","year":"2009","unstructured":"Wang S, Guo Z, Xia P, et al. Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res 2009; 19:1350\u20131362.","journal-title":"Cell Res"},{"key":"BFcr201550_CR44","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1038\/cr.2008.64","volume":"18","author":"P Xia","year":"2008","unstructured":"Xia P, Wang S, Guo Z, Yao X . Emperipolesis, entosis and beyond: dance with fate. Cell Res 2008; 18:705\u2013707.","journal-title":"Cell Res"},{"key":"BFcr201550_CR45","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1016\/j.cell.2007.10.040","volume":"131","author":"M Overholtzer","year":"2007","unstructured":"Overholtzer M, Mailleux AA, Mouneimne G, et al. A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion. Cell 2007; 131:966\u2013979.","journal-title":"Cell"},{"key":"BFcr201550_CR46","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/0046-8177(91)90079-5","volume":"22","author":"ZB Hang","year":"1991","unstructured":"Hang ZB, Wei YQ, Wang YP, Xu NR . Direct ultrastructural evidence of lymphocyte-mediated cancer cell lysis in the microenvironment of Chinese nasopharyngeal carcinoma. Hum Pathol 1991; 22:320\u2013325.","journal-title":"Hum Pathol"},{"key":"BFcr201550_CR47","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.1099\/0022-1317-82-10-2373","volume":"82","author":"S Maruo","year":"2001","unstructured":"Maruo S, Yang L, Takada K . Roles of Epstein-Barr virus glycoproteins gp350 and gp25 in the infection of human epithelial cells. J Gen Virol 2001; 82:2373\u20132383.","journal-title":"J Gen Virol"},{"key":"BFcr201550_CR48","first-page":"70","volume":"2","author":"S Gu","year":"1983","unstructured":"Gu S, Tang W, Zeng Y, Zhao M . An epithelsal cell line established from poorly differentiated nasopharyngeal carcinoma. Chin J Cancer 1983; 2:70\u201376.","journal-title":"Chin J Cancer"},{"key":"BFcr201550_CR49","doi-asserted-by":"crossref","first-page":"4788","DOI":"10.4049\/jimmunol.144.12.4788","volume":"144","author":"M Daibata","year":"1990","unstructured":"Daibata M, Humphreys RE, Takada K, Sairenji T . Activation of latent EBV via anti-IgG-triggered, second messenger pathways in the Burkitt's lymphoma cell line Akata. J Immunol 1990; 144:4788\u20134793.","journal-title":"J Immunol"},{"key":"BFcr201550_CR50","doi-asserted-by":"publisher","first-page":"9285","DOI":"10.1128\/JVI.00712-12","volume":"86","author":"A Nanbo","year":"2012","unstructured":"Nanbo A, Terada H, Kachi K, Takada K, Matsuda T . Roles of cell signaling pathways in cell-to-cell contact-mediated Epstein-Barr virus transmission. J Virol 2012; 86:9285\u20139296.","journal-title":"J Virol"},{"key":"BFcr201550_CR51","doi-asserted-by":"publisher","first-page":"2548","DOI":"10.1128\/JVI.80.5.2548-2565.2006","volume":"80","author":"J Yuan","year":"2006","unstructured":"Yuan J, Cahir-McFarland E, Zhao B, Kieff E . Virus and cell RNAs expressed during Epstein-Barr virus replication. J Virol 2006; 80:2548\u20132565.","journal-title":"J Virol"},{"key":"BFcr201550_CR52","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1126\/science.3012779","volume":"232","author":"A Faggioni","year":"1986","unstructured":"Faggioni A, Zompetta C, Grimaldi S, Barile G, Frati L, Lazdins J . Calcium modulation activates Epstein-Barr virus genome in latently infected cells. Science 1986; 232:1554\u20131556.","journal-title":"Science"},{"key":"BFcr201550_CR53","doi-asserted-by":"publisher","first-page":"6225","DOI":"10.1158\/0008-5472.CAN-06-0094","volume":"66","author":"LB Song","year":"2006","unstructured":"Song LB, Zeng MS, Liao WT, et al. Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. Cancer Res 2006; 66:6225\u20136232.","journal-title":"Cancer Res"},{"key":"BFcr201550_CR54","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1128\/JVI.66.1.122-131.1992","volume":"66","author":"M Rowe","year":"1992","unstructured":"Rowe M, Lear AL, Croom-Carter D, Davies AH, Rickinson AB . Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes. J Virol 1992; 66:122\u2013131.","journal-title":"J Virol"},{"key":"BFcr201550_CR55","doi-asserted-by":"publisher","first-page":"6135","DOI":"10.1128\/JVI.75.13.6135-6142.2001","volume":"75","author":"CD Darr","year":"2001","unstructured":"Darr CD, Mauser A, Kenney S . Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation. J Virol 2001; 75:6135\u20136142.","journal-title":"J Virol"},{"key":"BFcr201550_CR56","doi-asserted-by":"publisher","first-page":"7281","DOI":"10.1128\/JVI.00497-06","volume":"80","author":"R Jiang","year":"2006","unstructured":"Jiang R, Scott RS, Hutt-Fletcher LM . Epstein-Barr virus shed in saliva is high in B-cell-tropic glycoprotein gp42. J Virol 2006; 80:7281\u20137283.","journal-title":"J Virol"},{"key":"BFcr201550_CR57","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.arcmed.2014.02.002","volume":"45","author":"S Rosales-P\u00e9rez","year":"2014","unstructured":"Rosales-P\u00e9rez S, Cano-Valdez AM, Flores-Balc\u00e1zar CH, et al. Expression of Epstein-Barr virus-encoded latent membrane protein (LMP-1), p16 and p53 proteins in nonendemic nasopharyngeal carcinoma (NPC): a clinicopathological study. Arch Med Res 2014; 45:229\u2013236.","journal-title":"Arch Med Res"},{"key":"BFcr201550_CR58","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1038\/ncb2174","volume":"13","author":"M Krajcovic","year":"2011","unstructured":"Krajcovic M, Johnson NB, Sun Q, et al. A non-genetic route to aneuploidy in human cancers. Nat Cell Biol 2011; 13:324\u2013330.","journal-title":"Nat Cell Biol"},{"key":"BFcr201550_CR59","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1006\/cimm.1993.1114","volume":"148","author":"D Philp","year":"1993","unstructured":"Philp D, Pezzano M, Li Y, Omene C, Boto W, Guyden J . The binding, internalization, and release of thymocytes by thymic nurse cells. Cell Immunol 1993; 148:301\u2013315.","journal-title":"Cell Immunol"},{"key":"BFcr201550_CR60","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/s004410050037","volume":"299","author":"R Tsunoda","year":"2000","unstructured":"Tsunoda R, Heinen E, Sugai N . Follicular dendritic cells in vitro modulate the expression of Fas and Bcl-2 on germinal center B cells. Cell Tissue Res 2000; 299:395\u2013402.","journal-title":"Cell Tissue Res"},{"key":"BFcr201550_CR61","doi-asserted-by":"publisher","first-page":"16735","DOI":"10.1073\/pnas.1112251108","volume":"108","author":"V Benseler","year":"2011","unstructured":"Benseler V, Warren A, Vo M, et al. Hepatocyte entry leads to degradation of autoreactive CD8 T cells. Proc Natl Acad Sci USA 2011; 108:16735\u201316740.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFcr201550_CR62","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1038\/196080a0","volume":"196","author":"JG Sinkovics","year":"1962","unstructured":"Sinkovics JG . Intracellular lymphocytes in leukaemia. Nature 1962; 196:80\u201381.","journal-title":"Nature"},{"key":"BFcr201550_CR63","first-page":"1311","volume":"31","author":"M Benyesh-Melnick","year":"1963","unstructured":"Benyesh-Melnick M, Fernbach DJ, Lewis RT . Studies on human leukemia. I. Spontaneous lymphoblastoid transformation of fibroblastic bone marrow cultures derived from leukemic and nonleukemic children. J Natl Cancer Inst 1963; 31:1311\u20131325.","journal-title":"J Natl Cancer Inst"},{"key":"BFcr201550_CR64","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.canlet.2007.09.014","volume":"258","author":"S Fais","year":"2007","unstructured":"Fais S . Cannibalism: a way to feed on metastatic tumors. Cancer Lett 2007; 258:155\u2013164.","journal-title":"Cancer Lett"},{"key":"BFcr201550_CR65","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1038\/cr.2014.138","volume":"24","author":"Q Sun","year":"2014","unstructured":"Sun Q, Luo T, Ren Y, et al. Competition between human cells by entosis. Cell Res 2014; 24:1299\u20131310.","journal-title":"Cell Res"},{"key":"BFcr201550_CR66","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1038\/cr.2014.137","volume":"24","author":"Q Sun","year":"2014","unstructured":"Sun Q, Cibas ES, Huang H, Hodgson L, Overholtzer M . Induction of entosis by epithelial cadherin expression. Cell Res 2014; 24:1288\u20131298.","journal-title":"Cell Res"},{"key":"BFcr201550_CR67","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.yexmp.2010.09.004","volume":"89","author":"HL Chen","year":"2010","unstructured":"Chen HL, Peng J, Zhu XB, Gao J, Xue JL, Wang MW, Xia HS . Detection of EBV in nasopharyngeal carcinoma by quantum dot fluorescent in situ hybridization. Exp Mol Pathol 2010; 89:367\u2013371.","journal-title":"Exp Mol Pathol"}],"container-title":["Cell Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/cr201550.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cr201550","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/cr201550.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T17:14:07Z","timestamp":1691601247000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/cr201550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,28]]},"references-count":67,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["BFcr201550"],"URL":"https:\/\/doi.org\/10.1038\/cr.2015.50","relation":{},"ISSN":["1001-0602","1748-7838"],"issn-type":[{"value":"1001-0602","type":"print"},{"value":"1748-7838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,28]]},"assertion":[{"value":"12 January 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 February 2015","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2015","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2015","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}