{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T13:56:05Z","timestamp":1768485365837,"version":"3.49.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2010,9,15]],"date-time":"2010-09-15T00:00:00Z","timestamp":1284508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2010,9,15]],"date-time":"2010-09-15T00:00:00Z","timestamp":1284508800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Nutr"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1038\/ejcn.2010.165","type":"journal-article","created":{"date-parts":[[2010,9,15]],"date-time":"2010-09-15T09:01:38Z","timestamp":1284541298000},"page":"1302-1307","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Impact of maternal vitamin A supplementation on the mother\u2013infant pair in Brazil"],"prefix":"10.1038","volume":"64","author":[{"given":"T M","family":"Martins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I S","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J C","family":"Daneluzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"C E","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L A","family":"Del Ciampo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R G","family":"Ricco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"A A","family":"Jord\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Patta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Vannucchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,9,15]]},"reference":[{"issue":"Suppl","key":"BFejcn2010165_CR1","doi-asserted-by":"publisher","first-page":"S1206","DOI":"10.1093\/ajcn\/81.5.1206","volume":"81","author":"LH Allen","year":"2005","unstructured":"Allen LH (2005). Multiple micronutrients in pregnancy and lactation: an overview. Am J Clin Nutr 81 (Suppl), S1206\u2013S1212.","journal-title":"Am J Clin Nutr"},{"key":"BFejcn2010165_CR2","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/0378-4347(91)80476-S","volume":"572","author":"J Arnaud","year":"1991","unstructured":"Arnaud J, Fortis I, Blachier S, Kia D, Favier A (1991). Simultaneous determination of retinol \u03b1-tocopherol and \u03b2-carotene in serum by isocratic high-performance liquid chromatography. J Chromatogr 572, 103\u2013116.","journal-title":"J Chromatogr"},{"issue":"Suppl","key":"BFejcn2010165_CR3","doi-asserted-by":"publisher","first-page":"S1325","DOI":"10.1093\/ajcn\/71.5.1325s","volume":"71","author":"V Aza\u00efs-Braesco","year":"2000","unstructured":"Aza\u00efs-Braesco V, Pascal G (2000). Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 71 (Suppl), S1325\u2013S1333.","journal-title":"Am J Clin Nutr"},{"key":"BFejcn2010165_CR4","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1136\/pmj.79.933.397","volume":"79","author":"S Basu","year":"2003","unstructured":"Basu S, Sengupta B, Paladhi PKR (2003). Single megadose vitamin A supplementation of Indian mothers and morbidity in breastfed young infants. Postgrad Med J 79, 397\u2013402.","journal-title":"Postgrad Med J"},{"key":"BFejcn2010165_CR5","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/S0271-5317(00)00176-7","volume":"20","author":"P Bhaskaram","year":"2000","unstructured":"Bhaskaram P, Balakrishna N, Nair KM, Sivakumar B (2000). Vitamin A deficiency in infants: effects of postnatal maternal vitamin A supplementation on the growth and vitamin A status. Nutr Res 20, 769\u2013778.","journal-title":"Nutr Res"},{"key":"BFejcn2010165_CR6","unstructured":"Brasil Minist\u00e9rio da Sa\u00fade (2009). Pesquisa Nacional de Demografia e Sa\u00fade da Crian\u00e7a e da Mulher\u2014PNDS 2006: dimens\u00f5es do processo reprodutivo e da sa\u00fade da crian\u00e7a. Bras\u00edlia: Minist\u00e9rio da Sa\u00fade."},{"key":"BFejcn2010165_CR7","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/BF03405454","volume":"99","author":"C Cameron","year":"2008","unstructured":"Cameron C, Dallaire F, V\u00e9zina C, Muckle G, Bruneau S, Ayotte P et al. (2008). Neonatal vitamin A deficiency and its impact on acute respiratory infections among preschool Inuit children. Can J Public Health 99, 102\u2013106.","journal-title":"Can J Public Health"},{"key":"BFejcn2010165_CR8","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1590\/S0036-36341999000400009","volume":"41","author":"E Casanueva","year":"1999","unstructured":"Casanueva E, Vald\u00e9s-Ramos R, Pfeffer F, Ricalde-Moreno A, Garc\u00eda-Villegas E, Meza C (1999). Retinol s\u00e9rico en mujeres mexicanas urbanas durante el periodo perinatal. Salud Publica Mex 41, 317\u2013321.","journal-title":"Salud Publica Mex"},{"key":"BFejcn2010165_CR9","unstructured":"Centers for Disease Control and Prevention (2000). NCHS 2000. http:\/\/www.cdc.gov\/growthcharts\/."},{"key":"BFejcn2010165_CR10","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1038\/sj.ejcn.1602962","volume":"63","author":"VI Cust\u00f3dio","year":"2009","unstructured":"Cust\u00f3dio VI, Daneluzzi JS, Cust\u00f3dio RJ, Del Ciampo LA, Ferraz IS, Martinelli Jr CE et al. (2009). Vitamin A deficiency among Brazilian school-aged children in a healthy child service. Eur J Clin Nutr 63, 485\u2013490.","journal-title":"Eur J Clin Nutr"},{"issue":"Suppl","key":"BFejcn2010165_CR11","doi-asserted-by":"publisher","first-page":"S2895","DOI":"10.1093\/jn\/132.9.2895S","volume":"132","author":"S de Pee","year":"2002","unstructured":"de Pee S, Dary O (2002). Biochemical indicators of vitamin A deficiency: serum retinol and serum retinol binding protein. J Nutr 132 (Suppl), S2895\u2013S2901.","journal-title":"J Nutr"},{"key":"BFejcn2010165_CR12","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/S0271-5317(00)00177-9","volume":"20","author":"IS Ferraz","year":"2000","unstructured":"Ferraz IS, Daneluzzi JC, Vannucchi H (2000). Vitamin A deficiency in children aged 6\u201324 months in S\u00e3o Paulo State, Brazil. Nutr Res 20, 757\u2013768.","journal-title":"Nutr Res"},{"key":"BFejcn2010165_CR13","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1038\/sj.ejcn.1601978","volume":"58","author":"IS Ferraz","year":"2004","unstructured":"Ferraz IS, Daneluzzi JC, Vannucchi H, Jord\u00e3o Jr AA, Ricco RG, Del Ciampo LA et al. (2004). Detection of vitamin A deficiency in Brazilian preschool children using the serum 30-day dose-response test. Eur J Clin Nut 58, 1372\u20131377.","journal-title":"Eur J Clin Nut"},{"key":"BFejcn2010165_CR14","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1590\/S0036-36342009000400010","volume":"51","author":"A Garc\u00eda-Guerra","year":"2009","unstructured":"Garc\u00eda-Guerra A, Neufeld LM, Hern\u00e1ndez-Cordero S, Rivera J, Martorell R, Ramakrishnan U (2009). Prenatal multiple micronutrient supplementation impact on biochemical indicators during pregnancy and postpartum. Salud Publica Mex 51, 327\u2013335.","journal-title":"Salud Publica Mex"},{"key":"BFejcn2010165_CR15","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1023\/A:1018745812512","volume":"4","author":"MJ Haskell","year":"1999","unstructured":"Haskell MJ, Brown KH (1999). Maternal vitamin A nutriture and the vitamin A content of human milk. J Mam Gland Biol Neopl 4, 243\u2013257.","journal-title":"J Mam Gland Biol Neopl"},{"key":"BFejcn2010165_CR16","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1093\/clinchem\/35.9.2001","volume":"35","author":"TB Ledue","year":"1989","unstructured":"Ledue TB, Poulin SE, Leavitt LF, Johnson AM (1989). Evaluation of a particle-enhanced immunoassay for quantifying C-reactive protein. Clin Chem 35, 2001\u20132002.","journal-title":"Clin Chem"},{"key":"BFejcn2010165_CR17","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/tropej\/44.2.96","volume":"44","author":"BS Lindblad","year":"1998","unstructured":"Lindblad BS, Patel M, Hamadeh M, Helmy N, Ahmad I, Dawodu A et al. (1998). Age and sex are important factors in determining normal retinol levels. J Trop Pediatr 44, 96\u201399.","journal-title":"J Trop Pediatr"},{"key":"BFejcn2010165_CR18","volume-title":"SAS System for Mixed Models","author":"RC Littell","year":"1996","unstructured":"Littell RC, Milliken GA, Sroup WW, Wolfinger RD (1996). SAS System for Mixed Models. SAS Institute Inc.: Cary, NC."},{"key":"BFejcn2010165_CR19","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/clinchem\/43.1.52","volume":"43","author":"E Macy","year":"1997","unstructured":"Macy E, Hayes T, Tracy RP (1997). Variability in the measurement of C-reactive protein in healthy subjects: implications for reference interval and epidemiological applications. Clin Chem 43, 52\u201358.","journal-title":"Clin Chem"},{"issue":"Suppl","key":"BFejcn2010165_CR20","doi-asserted-by":"publisher","first-page":"S2867","DOI":"10.1093\/jn\/132.9.2867S","volume":"132","author":"M Miller","year":"2002","unstructured":"Miller M, Humphrey J, Johnson E, Marinda E, Brookmeyer R, Katz J (2002). Why do children become vitamin A deficient? Proceedings of the XX International Vitamin A Consultative Group Meeting. J Nutr 132 (Suppl), S2867\u2013S2880.","journal-title":"J Nutr"},{"key":"BFejcn2010165_CR21","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1093\/ajcn\/39.6.903","volume":"39","author":"JA Olson","year":"1984","unstructured":"Olson JA, Gunning DB, Tilton RA (1984). Liver concentrations of vitamin A and carotenoids as a function of age and other parameters of American children who died of various causes. Am J Clin Nutr 39, 903\u2013910.","journal-title":"Am J Clin Nutr"},{"key":"BFejcn2010165_CR22","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1093\/jn\/129.2.356","volume":"129","author":"AL Rice","year":"1999","unstructured":"Rice AL, Stoltzfus RJ, Francisco A, Chakraborty J, Kjolhede CL, Wahed MA (1999). Maternal vitamin A or \u03b2-carotene supplementation in lactating Bangladeshi women benefits mothers and infants but does not prevent subclinical deficiency. J Nutr 129, 356\u2013365.","journal-title":"J Nutr"},{"issue":"Suppl","key":"BFejcn2010165_CR23","doi-asserted-by":"publisher","first-page":"S2902","DOI":"10.1093\/jn\/132.9.2902S","volume":"132","author":"DA Ross","year":"2002","unstructured":"Ross DA (2002). Recommendations for vitamin A supplementation. Proceedings of the XX International Vitamin A Consultative Group Meeting. J Nutr 132 (Suppl), S2902\u2013S2906.","journal-title":"J Nutr"},{"key":"BFejcn2010165_CR24","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1038\/sj.ejcn.1600398","volume":"51","author":"SK Roy","year":"1997","unstructured":"Roy SK, Islam A, Molla A, Akramuzzaman SM, Jahan F, Fuchs G (1997). Impact of a single megadose of vitamin A at delivery on breast milk of mothers and morbidity of their infants. Eur J Clin Nutr 51, 302\u2013307.","journal-title":"Eur J Clin Nutr"},{"key":"BFejcn2010165_CR25","unstructured":"SAS Institute Inc. 2002. SAS\/STAT\u00ae User's Guide, Version 9. SAS Institute Inc.: Cary, NC."},{"key":"BFejcn2010165_CR26","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1093\/biomet\/78.4.719","volume":"78","author":"R Schall","year":"1991","unstructured":"Schall R (1991). Estimation in generalized linear models with random effects. Biometrika 78, 719\u2013727.","journal-title":"Biometrika"},{"key":"BFejcn2010165_CR27","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1079\/BJN2001444","volume":"86","author":"MK Schmidt","year":"2001","unstructured":"Schmidt MK, Muslimatun S, West CE, Schultink W, Hautvast JGAJ (2001). Vitamin A and iron supplementation of Indonesian pregnant women benefits vitamin A status of their infants. Br J Nutr 86, 607\u2013615.","journal-title":"Br J Nutr"},{"key":"BFejcn2010165_CR28","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1093\/jn\/138.10.1835","volume":"138","author":"A Sommer","year":"2008","unstructured":"Sommer A (2008). Vitamin A deficiency and clinical disease: an historical overview. J Nutr 138, 1835\u20131839.","journal-title":"J Nutr"},{"key":"BFejcn2010165_CR29","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1093\/jn\/123.4.666","volume":"123","author":"RJ Stoltzfus","year":"1993","unstructured":"Stoltzfus RJ, Hakimi M, Miller KW, Rasmussen KM, Dawiesah S, Habicht JP et al. (1993). High dose vitamin A supplementation of breast-feeding Indonesian mothers: effects on the vitamin A status of mother and infant. J Nutr 123, 666\u2013675.","journal-title":"J Nutr"},{"key":"BFejcn2010165_CR30","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/S0021-9673(00)00860-8","volume":"898","author":"M Strobel","year":"2000","unstructured":"Strobel M, Heinrich F, Biesalski HK (2000). Improved method for rapid determination of vitamin A in small samples of breast milk by high-performance liquid chromatography. J Chromatogr A 898, 179\u2013183.","journal-title":"J Chromatogr A"},{"issue":"Suppl","key":"BFejcn2010165_CR31","doi-asserted-by":"publisher","first-page":"S290","DOI":"10.1093\/jn\/134.1.290S","volume":"134","author":"SA Tanumihardjo","year":"2004","unstructured":"Tanumihardjo SA (2004). Assessing vitamin A status: past present and future. J Nutr 134 (Suppl), S290\u2013S293.","journal-title":"J Nutr"},{"issue":"Suppl 4","key":"BFejcn2010165_CR32","doi-asserted-by":"publisher","first-page":"S508","DOI":"10.1590\/S0036-36342003001000007","volume":"45","author":"S Villalpando","year":"2003","unstructured":"Villalpando S, Montalvo-Velarde I, Zambrano N, Garc\u00eda-Guerra A, Ram\u00edrez-Silva CI, Shamah-Levy T et al. (2003). Vitamins A, and C and folate status in Mexican children under 12 years and women 12\u201349 years: A probabilistic national survey. Salud Publica Mex 45 (Suppl 4), S508\u2013S519.","journal-title":"Salud Publica Mex"},{"key":"BFejcn2010165_CR33","first-page":"1188","volume":"37","author":"B Vinutha","year":"2000","unstructured":"Vinutha B, Mehta MN, Shanbag P (2000). Vitamin A status of pregnant women and effect of post partum vitamin A supplementation. Indian Pediatr 37, 1188\u20131193.","journal-title":"Indian Pediatr"},{"issue":"Suppl","key":"BFejcn2010165_CR34","doi-asserted-by":"publisher","first-page":"S2857","DOI":"10.1093\/jn\/132.9.2857S","volume":"132","author":"KP West Jr","year":"2002","unstructured":"West Jr KP (2002). Extent of vitamin A deficiency among preschool children and women of reproductive age. J Nutr 132 (Suppl), S2857\u2013S2866.","journal-title":"J Nutr"},{"key":"BFejcn2010165_CR35","unstructured":"World Health Organization (1995). Physical Status: The use and Interpretation of Anthropometry, Report of a WHO Expert Committee (Technical Reports Series No 854). WHO: Geneva."},{"key":"BFejcn2010165_CR36","unstructured":"World Health Organization (1996). Indicators for assessing Vitamin A Deficiency and their Application in Monitoring and Evaluating Intervention Programmes, (Document WHO\/NUT\/96.10) WHO: Geneva."},{"key":"BFejcn2010165_CR37","unstructured":"World Health Organization (1998). Obesity: Preventing and Managing the Global Epidemic. WHO: Geneva."},{"key":"BFejcn2010165_CR38","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/clinchem\/33.5.685","volume":"33","author":"J Winkles","year":"1987","unstructured":"Winkles J, Lunec J, Deverill I (1987). Enhanced-latex-agglutination assay for C-reactive protein in serum with use of a centrifugal analyzer. Clin Chem 33, 685\u2013689.","journal-title":"Clin Chem"}],"container-title":["European Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/ejcn2010165.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ejcn2010165","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ejcn2010165.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T12:46:46Z","timestamp":1648212406000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ejcn2010165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,15]]},"references-count":38,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["BFejcn2010165"],"URL":"https:\/\/doi.org\/10.1038\/ejcn.2010.165","relation":{},"ISSN":["0954-3007","1476-5640"],"issn-type":[{"value":"0954-3007","type":"print"},{"value":"1476-5640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,15]]},"assertion":[{"value":"30 October 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 July 2010","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2010","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2010","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}