{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T09:27:17Z","timestamp":1782552437026,"version":"3.54.5"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1998,9,1]],"date-time":"1998-09-01T00:00:00Z","timestamp":904608000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[1998,9]]},"DOI":"10.1038\/eye.1998.224","type":"journal-article","created":{"date-parts":[[2011,7,4]],"date-time":"2011-07-04T11:14:19Z","timestamp":1309778059000},"page":"886-890","source":"Crossref","is-referenced-by-count":25,"title":["Cellular and plasma fibronectin in the aqueous humour of primary open-angle glaucoma, exfoliative glaucoma and cataract patients"],"prefix":"10.1038","volume":"12","author":[{"given":"Minna","family":"Vesaluoma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e4ivi","family":"Mertaniemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari","family":"Mannonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkka","family":"Lehto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Risto","family":"Uusitalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seppo","family":"Sarna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahti","family":"Tarkkanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Tervo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BFeye1998224_CR1","first-page":"797","volume":"26","author":"BB Floyd","year":"1985","unstructured":"Floyd BB, Cleveland PH, Worthen DM . Fibronectin in human trabecular drainage channels. Invest Ophthalmol Vis Sci 1985;26:797\u2013804.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR2","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/0002-9394(87)90290-X","volume":"104","author":"CG Murphy","year":"1987","unstructured":"Murphy CG, Yun AJ, Newsome DA, Alvarado JA . Localization of extracellular proteins of the human trabecular meshwork by indirect immunofluorescence. Am J Ophthalmol 1987;104:33\u201343.","journal-title":"Am J Ophthalmol"},{"key":"BFeye1998224_CR3","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1159\/000267012","volume":"22","author":"T Tervo","year":"1990","unstructured":"Tervo T, van Setten G-B, Lehto I, Tervo K, Tarkkanen A, Virtanen I . Immunohistochemical demonstration of tenascin in the normal human limbus with special reference to trabeculectomy. Ophthalmic Res 1990;22:128\u201333.","journal-title":"Ophthalmic Res"},{"key":"BFeye1998224_CR4","first-page":"1845","volume":"35","author":"J Terttunen","year":"1994","unstructured":"Terttunen J, Palkama A, Virtanen I, Uusitalo H . Immunohistochemical characterization of tenascin, laminin and collagen IV in human trabecular outflow channel. Invest Ophthalmol Vis Sci (Suppl) 1994;35:1845.","journal-title":"Invest Ophthalmol Vis Sci (Suppl)"},{"key":"BFeye1998224_CR5","first-page":"181","volume":"32","author":"BJ Tripathi","year":"1991","unstructured":"Tripathi BJ, Tripathi RC, Yang C, Millard CB, Dixit VM . Synthesis of a thrombospondin-like cytoadhesion molecule by cells of the trabecular meshwork. Invest Ophthalmol Vis Sci 1991;32:181\u20138.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR6","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.3109\/02713688908997400","volume":"8","author":"H Gong","year":"1989","unstructured":"Gong H, Trinkaus-Randall V, Freddo TF . Ultrastructural immunocytochemical localization of elastin in normal human trabecular meshwork. Curr Eye Res 1989;8:1071\u201382.","journal-title":"Curr Eye Res"},{"key":"BFeye1998224_CR7","first-page":"486","volume":"35","author":"J Umihira","year":"1994","unstructured":"Umihira J, Nagata S, Nohara S, Hanai T, Usuda N, Segawa K . Localization of elastin in the normal and glaucomatous human trabecular meshwork. Invest Ophthalmol Vis Sci 1994;35:486\u201394.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR8","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1001\/archopht.1995.01100100107039","volume":"113","author":"G Gonzalez-Avila","year":"1995","unstructured":"Gonzalez-Avila G, Ginebra M, Hayakawa T, et al. Collagen metabolism in human aqueous humor from primary open-angle glaucoma: decreased degradation and increased biosynthesis play a role in its pathogenesis. Arch Ophthalmol 1995;113:1319\u201323.","journal-title":"Arch Ophthalmol"},{"key":"BFeye1998224_CR9","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.1016\/S0021-9258(18)32672-3","volume":"258","author":"JW Tamkun","year":"1983","unstructured":"Tamkun JW, Hynes RO . Plasma fibronectin is synthesized and secreted by hepatocytes. J Biol Chem 1983;258:4641\u20137.","journal-title":"J Biol Chem"},{"key":"BFeye1998224_CR10","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1242\/jcs.88.4.419","volume":"88","author":"T Vartio","year":"1987","unstructured":"Vartio T, Laitinen L, N\u00e4rv\u00e4nen O, et al. Differential expression of the ED sequence-containing form of cellular fibronectin in embryonic and adult human tissues. J Cell Sci 1987;88:419\u201330.","journal-title":"J Cell Sci"},{"key":"BFeye1998224_CR11","first-page":"71","volume":"67","author":"VE Gould","year":"1992","unstructured":"Gould VE, Martinez-Lacabe V, Virtanen L . Sahlin KM, Schwarz MM. Differential distribution of tenascin and cellular fibronectin in acute and chronic renal allograft rejection. Lab Invest 1992;67:71\u20139.","journal-title":"Differential distribution of tenascin and cellular fibronectin in acute and chronic renal allograft rejection. Lab Invest"},{"key":"BFeye1998224_CR12","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/0047-6374(89)90017-1","volume":"47","author":"MA Babizhayev","year":"1989","unstructured":"Babizhayev MA, Brodskaya MW . Fibronectin detection in drainage outflow system of human eyes in ageing and progression of open-angle glaucoma. Mech Ageing Dev 1989;47:145\u201357.","journal-title":"Mech Ageing Dev"},{"key":"BFeye1998224_CR13","first-page":"2012","volume":"30","author":"AJ Yun","year":"1989","unstructured":"Yun AJ, Murphy CG, Polansky JR, Newsome DA, Alvarado JA . Proteins secreted by human trabecular cells: glucocorticoid and other effects. Invest Ophthalmol Vis Sci 1989;30:2012\u201322.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR14","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0092-8674(86)90374-0","volume":"47","author":"R Chiquet-Ehrismann","year":"1986","unstructured":"Chiquet-Ehrismann R, Mackie EJ, Pearson CA, Sakakura T . Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis. Cell 1986;47:131\u20139.","journal-title":"Cell"},{"key":"BFeye1998224_CR15","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1146\/annurev.cb.05.110189.000443","volume":"5","author":"HP Erickson","year":"1989","unstructured":"Erickson HP, Bourdon MA . Tenascin: an extracellular matrix protein prominent in specialized embryonic tissues and tumors. Annu Rev Cell Biol 1989;5:71\u201392.","journal-title":"Annu Rev Cell Biol"},{"key":"BFeye1998224_CR16","first-page":"2912","volume":"32","author":"K Tervo","year":"1991","unstructured":"Tervo K, van Setten G-B, Beuerman RW, Virtanen I, Tarkkanen A, Tervo T . Expression of tenascin and cellular fibronectin in the rabbit cornea after anterior keratectomy: immunohistochemical study of wound healing dynamics. Invest Ophthalmol Vis Sci 1991;32:2912\u20138.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR17","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1007\/BF00164660","volume":"230","author":"G-B van Setten","year":"1992","unstructured":"van Setten G-B, Koch JW, Tervo K, et al. Expression of tenascin and fibronectin in the rabbit cornea after excimer laser surgery. Graefes Arch Clin Exp Ophthalmol 1992;230:178\u201383.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"BFeye1998224_CR18","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1002\/cne.902330410","volume":"233","author":"G Terenghi","year":"1985","unstructured":"Terenghi G, Polak JM, Ghatei MA, et al. Distribution and origin of calcitonin gene-related peptide (CGRP) immunoreactivity in the sensory innervation of the mammalian eye. J Comp Neurol 1985;233:506\u201316.","journal-title":"J Comp Neurol"},{"key":"BFeye1998224_CR19","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/0014-4835(88)90011-5","volume":"47","author":"O Oksala","year":"1988","unstructured":"Oksala O . Effects of calcitonin gene-related peptide and substance P on the regional blood flow in the cat eye. Exp Eye Res 1988;47:283\u20139.","journal-title":"Exp Eye Res"},{"key":"BFeye1998224_CR20","first-page":"1006","volume":"29","author":"O Oksala","year":"1988","unstructured":"Oksala O, Stjernschantz J . Effects of calcitonin gene-related peptide in the eye: a study in rabbits and cats. Invest Ophthalmol Vis Sci 1988;29:1006\u201311.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR21","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/0167-0115(86)90054-6","volume":"16","author":"C Wahlestedt","year":"1986","unstructured":"Wahlestedt C, Beding B, Ekman R, Oksala O, Stjernschantz J, H\u00e5kanson R . Calcitonin gene-related peptide in the eye: release by sensory nerve stimulation and effects associated with neurogenic inflammation. Reg Peptides 1986;16:107\u201315.","journal-title":"Reg Peptides"},{"key":"BFeye1998224_CR22","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/0014-4835(88)90045-0","volume":"47","author":"O Oksala","year":"1988","unstructured":"Oksala O, Stjernschanz J . Increase in outflow facility of aqueous humor in cats induced by calcitonin gene-related peptide. Exp Eye Res 1988;47:787\u201390.","journal-title":"Exp Eye Res"},{"key":"BFeye1998224_CR23","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1089\/jop.1993.9.77","volume":"9","author":"B Almeg\u00e5rd","year":"1993","unstructured":"Almeg\u00e5rd B, Andersson SE . Vascular effects of calcitonin gene-related peptide (CGRP) and cholecystokinin (CKK) in the monkey eye. J Ocular Pharmacol 1993;9:77\u201384.","journal-title":"J Ocular Pharmacol"},{"key":"BFeye1998224_CR24","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/0014-4835(90)90053-W","volume":"51","author":"B Almeg\u00e5rd","year":"1990","unstructured":"Almeg\u00e5rd B, Andersson SE . Outflow facility in the monkey eye: effects of calcitonin gene-related peptide, cholecystokinin, galatin, substance P and capsaicin. Exp Eye Res 1990;51:685\u20139.","journal-title":"Exp Eye Res"},{"key":"BFeye1998224_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3341\/kjo.1992.6.1.1","volume":"6","author":"KS Kim","year":"1992","unstructured":"Kim KS, Lee BH, Kim IS . Measurement of fibronectin concentrations in human aqueous humor. Korean J Ophthalmol 1992;6:1\u20135.","journal-title":"Korean J Ophthalmol"},{"key":"BFeye1998224_CR26","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0009-8981(94)05978-2","volume":"234","author":"S Yl\u00e4tupa","year":"1995","unstructured":"Yl\u00e4tupa S, Mertaniemi P, Haglund C, Partanen P . An improved method for quantification of extra domain A-containing cellular fibronectin (EDAcFN) in different body fluids. Clin Chim Acta 1995;234:79\u201390.","journal-title":"Clin Chim Acta"},{"key":"BFeye1998224_CR27","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/0009-9120(94)00079-B","volume":"28","author":"S Yl\u00e4tupa","year":"1995","unstructured":"Yl\u00e4tupa S, Mertaniemi P, Haglund C, Partanen P . Enzyme immunoassay for quantification of tenascin in biologic samples. Clin Biochem 1995;28:263\u20138.","journal-title":"Clin Biochem"},{"key":"BFeye1998224_CR28","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/S0014-4835(05)80007-7","volume":"60","author":"P Mertaniemi","year":"1995","unstructured":"Mertaniemi P, Yl\u00e4tupa S, Partanen P, Tervo T . Increased release of immunoreactive calcitonin gene-related peptide (CGRP) in tears after excimer laser keratectomy. Exp Eye Res 1995;60:659\u201365.","journal-title":"Exp Eye Res"},{"key":"BFeye1998224_CR29","first-page":"748","volume":"35","author":"M K\u00fcchle","year":"1994","unstructured":"K\u00fcchle M, Ho TS, Nguyen NX, Hannappel E, Naumann GOH . Protein quantification and electrophoresis in aqueous humor of pseudoexfoliation eyes. Invest Ophthalmol Vis Sci 1994;35:748\u201352.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR30","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/j.1600-0420.1995.tb00278.x","volume":"73","author":"J Moreno-Montanes","year":"1995","unstructured":"Moreno-Montanes J, Lajara Blesa J . IgG, albumin and total IgG index in the aqueous humour of eyes with pseudoexfoliation syndrome. Acta Ophthalmol Scand 1995;73:249\u201351.","journal-title":"Acta Ophthalmol Scand"},{"key":"BFeye1998224_CR31","doi-asserted-by":"publisher","first-page":"343","DOI":"10.3109\/02713689209001788","volume":"11","author":"U Schl\u00f6tzer-Schrehardt","year":"1992","unstructured":"Schl\u00f6tzer-Schrehardt U, D\u00f6rfler S, Naumann GOH . Immunohistochemical localization of basement membrane components in pseudoexfoliation material of the lens capsule. Curr Eye Res 1992;11:343\u201355.","journal-title":"Curr Eye Res"},{"key":"BFeye1998224_CR32","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1146\/annurev.bi.57.070188.002111","volume":"57","author":"E Ruoslahti","year":"1988","unstructured":"Ruoslahti E . Fibronectin and its receptors. Annu Rev Biochem 1988;57:375\u2013413.","journal-title":"Annu Rev Biochem"},{"key":"BFeye1998224_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1172\/JCI114957","volume":"87","author":"E Ruoslahti","year":"1991","unstructured":"Ruoslahti E . Integrins. J Clin Invest 1991;87:1\u20135.","journal-title":"J Clin Invest"},{"key":"BFeye1998224_CR34","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/BF00177651","volume":"233","author":"K Tervo","year":"1995","unstructured":"Tervo K, P\u00e4\u00e4llysaho T, Virtanen I, Tervo T . Integrins in human anterior chamber angle. Graefes Arch Clin Exp Ophthalmol 1995;233:291\u20135.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"BFeye1998224_CR35","unstructured":"Tarkkanen A . Pseudoexfoliation of the lens capsule: a clinical study of 418 patients with special reference to glaucoma, cataract and changes of the vitreous. Acta Ophthalmol (Copenh) 1962;Suppl 71:1\u201398."},{"key":"BFeye1998224_CR36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0047-6374(93)90126-C","volume":"72","author":"MA Babizhayev","year":"1993","unstructured":"Babizhayev MA, Brodskaya MW . Immunohistochemical monitoring of the effect of a synthetic fibronectin-like peptide (Arg-Gly-Asp) on the age-related changes in the isolated human corneoscleral tissue of glaucomatous eyes. Mech Ageing Dev 1993;72:1\u201312.","journal-title":"Mech Ageing Dev"},{"key":"BFeye1998224_CR37","doi-asserted-by":"publisher","first-page":"4167","DOI":"10.1073\/pnas.83.12.4167","volume":"83","author":"AB Roberts","year":"1986","unstructured":"Roberts AB, Sporn MB, Assoian RK, et al. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 1986;83:4167\u201371.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFeye1998224_CR38","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1016\/S0021-9258(17)35666-1","volume":"261","author":"RA Ignotz","year":"1986","unstructured":"Ignotz RA, Massague J . Transforming growth factor-\u03b2 stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986;261:4337\u201345.","journal-title":"J Biol Chem"},{"key":"BFeye1998224_CR39","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3109\/02713689308995765","volume":"12","author":"M Ohji","year":"1993","unstructured":"Ohji M, SundarRaj N, Thoft RA . Transforming growth factor-\u03b2 stimulates collagen and fibronectin synthesis by human corneal stromal fibroblasts in vitro. Curr Eye Res 1993;12:703\u20139.","journal-title":"Curr Eye Res"},{"key":"BFeye1998224_CR40","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1006\/exer.1994.1158","volume":"59","author":"RC Tripathi","year":"1994","unstructured":"Tripathi RC, Li J, Chan WFA, Tripathi BJ . Aqueous humor in glaucomatous eyes contains an increased level of TGF-\u03b22. Exp Eye Res 1994;59:723\u20138.","journal-title":"Exp Eye Res"},{"key":"BFeye1998224_CR41","first-page":"1341","volume":"28","author":"JK Park","year":"1987","unstructured":"Park JK, Tripathi RC, Tripathi BJ, Barlow GH . Tissue plasminogen activator in the trabecular endothelium. Invest Ophthalmol Vis Sci 1987;28:1341\u20135.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR42","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/0002-9394(88)90707-6","volume":"106","author":"RC Tripathi","year":"1988","unstructured":"Tripathi RC, Park JK, Tripathi BJ, Millard CB . Tissue plasminogen activator in human aqueous humor and its possible therapeutic significance. Am J Ophthalmol 1988;106:719\u201322.","journal-title":"Am J Ophthalmol"},{"key":"BFeye1998224_CR43","first-page":"2687","volume":"33","author":"SF Bernatchez","year":"1992","unstructured":"Bernatchez SF, Tabatabay C, Belin D . Urokinase-type plasminogen activator in human aqueous humor. Invest Ophthalmol Vis Sci 1992;33:2687\u201392.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR44","first-page":"48","volume":"35","author":"DM Smalley","year":"1994","unstructured":"Smalley DM, Fitzgerald JE, Taylor DM, Cone RE, O'Rourke J . Tissue plasminogen activator activity in human aqueous humor. Invest Ophthalmol Vis Sci 1994;35:48\u201353.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye1998224_CR45","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1172\/JCI115405","volume":"88","author":"JD Vassalli","year":"1991","unstructured":"Vassalli JD, Sappino AP, Belin D . The plasminogen activator\/plasmin system. J Clin Invest 1991;88:1067\u201372.","journal-title":"J Clin Invest"},{"key":"BFeye1998224_CR46","first-page":"111","volume":"114","author":"A Vaheri","year":"1985","unstructured":"Vaheri A, Salonen EM, Vartio T . Fibronectin in the formation and degradation of the pericellular matrix. Ciba Found Symp 1985;114:111\u201326.","journal-title":"Ciba Found Symp"},{"key":"BFeye1998224_CR47","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1016\/S0002-9394(14)72552-8","volume":"118","author":"U Schl\u00f6tzer-Schrehardt","year":"1994","unstructured":"Schl\u00f6tzer-Schrehardt U, Naumann GOH . A histopathologic study of zonular instability in pseudoexfoliation syndrome. Am J Ophthalmol 1994;118:730\u201343.","journal-title":"Am J Ophthalmol"},{"key":"BFeye1998224_CR48","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/BF00183428","volume":"233","author":"M Vesaluoma","year":"1995","unstructured":"Vesaluoma M, Yl\u00e4tupa S, Mertaniemi P, Tervo K, Partanen P, Tervo T . Increased release of tenascin in tear fluid after photorefractive keratectomy. Graefes Arch Clin Exp Ophthalmol 1995;233:479\u201383.","journal-title":"Graefes Arch Clin Exp Ophthalmol"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/eye1998224.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye1998224","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye1998224.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T17:40:33Z","timestamp":1684431633000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/eye1998224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,9]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,9]]}},"alternative-id":["BFeye1998224"],"URL":"https:\/\/doi.org\/10.1038\/eye.1998.224","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,9]]}}}