{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T22:49:45Z","timestamp":1788216585016,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2008,10,24]],"date-time":"2008-10-24T00:00:00Z","timestamp":1224806400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1038\/eye.2008.305","type":"journal-article","created":{"date-parts":[[2008,10,24]],"date-time":"2008-10-24T09:52:58Z","timestamp":1224841978000},"page":"1288-1294","source":"Crossref","is-referenced-by-count":123,"title":["Penetrating keratoplasty: indications, outcomes, and complications"],"prefix":"10.1038","volume":"23","author":[{"given":"I","family":"Rahman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Carley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Hillarby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Brahma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A B","family":"Tullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,10,24]]},"reference":[{"key":"BFeye2008305_CR1","unstructured":"UK Transplant web site. \n                    http:\/\/www.uktransplant.org.uk\/ukt\/statistics\/statistics.jsp\n                    \n                  . Accessed 22nd June 2007."},{"key":"BFeye2008305_CR2","unstructured":"Eye Bank Association of America web site. \n                    www.Restoresight.org\/newsroom\/newsroom.htm\n                    \n                  .Accessed 22nd June 2007."},{"key":"BFeye2008305_CR3","unstructured":"Mc Neill JI . Penetrating keratoplasty: preoperative considerations; indications and outcomes. In: Krachmer JH, Mannis MJ, Holland EJ (eds). Mosby: Cornea, St Louis, 1997; 3, chapter 127, pp 1551\u20131561."},{"key":"BFeye2008305_CR4","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/S0161-6420(91)32292-9","volume":"98","author":"FW Price","year":"1991","unstructured":"Price FW, Whitson WE, Marks RG . Graft survival in four common groups of patients undergoing penetrating keratoplasty. Ophthalmology 1991; 98: 322\u2013328.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR5","first-page":"244","volume":"1","author":"AE Maumenee","year":"1962","unstructured":"Maumenee AE . Clinical aspects of the corneal homograft reaction. Invest Ophthalmol 1962; 1: 244\u2013252.","journal-title":"Invest Ophthalmol"},{"key":"BFeye2008305_CR6","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1136\/bjo.84.1.60","volume":"84","author":"A Brahma","year":"2000","unstructured":"Brahma A, Ennis F, Harper R, Ridgway A, Tullo A . Visual function after penetrating keratoplasty for keratoconus: a prospective longitudinal evaluation. Br J Ophthalmol 2000; 84: 60\u201366.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2008305_CR7","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/S0161-6420(94)31376-5","volume":"101","author":"A Vail","year":"1994","unstructured":"Vail A, Gore SM, Bradley BA, Easty DL, Rogers CA . Corneal graft survival and visual outcome. A multicentre study. Corneal Transplant Follow-up Study Collaborators. Ophthalmology 1994; 101: 120\u2013127.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR8","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1136\/bjo.2005.086272","volume":"90","author":"P Beckingsale","year":"2006","unstructured":"Beckingsale P, Mavrikakis I, Al-Yousuf N, Mavrikakis E, Daya SM . Penetrating keratoplasty: outcomes from a corneal unit compared to national data. Br J Ophthalmol 2006; 90: 728\u2013731.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2008305_CR9","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.1016\/S0161-6420(98)91030-2","volume":"105","author":"JJ Ing","year":"1998","unstructured":"Ing JJ, Ing HH, Nelson LR, Hodge DO, Bourne WM . Ten year postoperative results of penetrating keratoplasty. Ophthalmology 1998; 105: 1855\u20131865.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR10","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1016\/S0161-6420(94)31138-9","volume":"101","author":"MG Maguire","year":"1994","unstructured":"Maguire MG, Stark WJ, Gottsch JD, Stulting RD, Sugar A, Fink NE et al. Risk factors for corneal graft failure and rejection in the collaborative corneal transplantation studies. Collaborative Corneal Transplantation Studies Research Group. Ophthalmology 1994; 101: 1536\u20131547.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1442-9071.1993.tb00121.x","volume":"21","author":"KA Williams","year":"1993","unstructured":"Williams KA, Muehlberg SM, Wing SJ, Coster DJ . The Australian Corneal Graft Registry:1990 to 1992 report. Aust NZJ Ophthalmol 1993; 21: 1\u201348.","journal-title":"Aust NZJ Ophthalmol"},{"key":"BFeye2008305_CR12","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/S0161-6420(94)31376-5","volume":"101","author":"A Vail","year":"1994","unstructured":"Vail A, Gore SM, Bradley BA, Easty DL, Rogers CA . Corneal graft survival and visual outcome: a multicentre study. Ophthalmology 1994; 101: 120\u2013127.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR13","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1001\/archopht.1993.01090060087029","volume":"111","author":"FW Price Jr","year":"1993","unstructured":"Price Jr FW, Whitson WE, Collins KS, Marks RG . Five-year corneal graft survival: a large, single-centre patient cohort. Arch Ophthalmol 1993; 111: 799\u2013805.","journal-title":"Arch Ophthalmol"},{"key":"BFeye2008305_CR14","unstructured":"Bradley BA, Vail A, Gore SM, Rogers CA, Armitage WJ, Nicholls SM et al. Penetrating keratoplasty in the United Kingdom: an interim analysis of the Corneal Transplant Follow-up Study. Clin Transpl 1993; 293\u2013315."},{"key":"BFeye2008305_CR15","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1136\/bjo.81.9.726","volume":"81","author":"L Dandona","year":"1997","unstructured":"Dandona L, Naduvilath TJ, Janarthanan M, Ragu K, Rao GN . Survival analysis and visual outcome in a large series of corneal transplants in India. Br J Ophthalmol 1997; 81: 726\u2013731.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2008305_CR16","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1111\/j.1442-9071.1987.tb00300.x","volume":"15","author":"HJM Volker-Dieben","year":"1987","unstructured":"Volker-Dieben HJM, D\u2019Amaro J, Kok-van Alpen CC . Hierarchy of prognostic factors for corneal allograft survival. Aust NZJ Ophthalmol 1987; 15: 11\u201318.","journal-title":"Aust NZJ Ophthalmol"},{"key":"BFeye2008305_CR17","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/S0161-6420(87)33356-1","volume":"94","author":"RJ Epstein","year":"1987","unstructured":"Epstein RJ, Seedor JA, Dreizen NG, Stulting RD, Waring III GO, Wilson LA et al. Penetrating keratoplasty for herpes simplex keratitis and keratoconus: allograft rejection and survival. Ophthalmology 1987; 94: 935\u2013942.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR18","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1136\/bjo.80.10.890","volume":"80","author":"D Yorston","year":"1996","unstructured":"Yorston D, Wood M, Foster A . Penetrating keratoplasty in Africa: graft survival and visual outcome. Br J Ophthalmol 1996; 80: 890\u2013894.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2008305_CR19","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1097\/00003226-200103000-00002","volume":"20","author":"M Sit","year":"2001","unstructured":"Sit M, Weisbrod DJ, Naor J, Slomovic AR . Corneal graft outcome study. Cornea 2001; 20: 129\u2013133.","journal-title":"Cornea"},{"key":"BFeye2008305_CR20","first-page":"1398","volume":"119","author":"RW Thompson","year":"2003","unstructured":"Thompson RW, Price MO, Bowers PJ, Price Jr FW . Long term graft survival after penetrating keratoplasty. Ophthalmology 2003; 119: 1398\u20131402.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR21","first-page":"2034","volume":"24","author":"U Peleyer","year":"1992","unstructured":"Peleyer U, Steuhl KP, Weidle EG, Lisch W, Thiel HJ . Corneal graft rejection: incidence, manifestation, and interaction of clinical subtypes. Transplant Proc 1992; 24: 2034\u20132037.","journal-title":"Transplant Proc"},{"key":"BFeye2008305_CR22","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1001\/archopht.1981.03930010599002","volume":"99","author":"OC Alldredge","year":"1981","unstructured":"Alldredge OC, Krachmer JH . Clinical types of corneal transplant rejection. Their manifestations, frequency, preoperative correlates and treatment. Arch Ophthalmol 1981; 99: 599\u2013604.","journal-title":"Arch Ophthalmol"},{"key":"BFeye2008305_CR23","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/0002-9394(74)90469-3","volume":"77","author":"JW Chandler","year":"1974","unstructured":"Chandler JW, Kaufman HE . Graft reactions after keratoplasty for keratoconus. Am J Ophthalmol 1974; 77: 543\u2013547.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2008305_CR24","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1136\/bjo.75.3.142","volume":"75","author":"KW Sharif","year":"1991","unstructured":"Sharif KW, Casey TA . Penetrating keratoplasty for keratoconus: complications and long-term success. Br J Ophthalmol 1991; 75: 142\u2013146.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2008305_CR25","first-page":"106","volume":"37","author":"TE Moore Jr","year":"1978","unstructured":"Moore Jr TE, Aronson SB . Results of penetrating keratoplasty in Keratoconus. Adv Ophthalmol 1978; 37: 106\u2013108.","journal-title":"Adv Ophthalmol"},{"key":"BFeye2008305_CR26","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1111\/j.1600-0420.1996.tb00068.x","volume":"74","author":"A Koralewska-Makar","year":"1996","unstructured":"Koralewska-Makar A, Floren I, Stenevi U . The results of penetrating keratoplasty for Keratoconus. Acta Ophthalmol Scand 1996; 74: 187\u2013190.","journal-title":"Acta Ophthalmol Scand"},{"key":"BFeye2008305_CR27","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1016\/S0002-9394(14)73636-0","volume":"115","author":"AM Chien","year":"1993","unstructured":"Chien AM, Schmidt CM, Cohen EJ, Rajpal RK, Sperber LT, Rapuano CJ et al. Glaucoma in the immediate postoperative period after penetrating keratoplasty. Am J Ophthalmol 1993; 115: 711\u2013714.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2008305_CR28","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1016\/S0161-6420(87)33542-0","volume":"94","author":"GN Foulks","year":"1987","unstructured":"Foulks GN . Glaucoma associated with penetrating keratoplasty. Ophthalmology 1987; 94: 871\u2013874.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR29","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/0002-9394(81)90527-4","volume":"92","author":"DB Goldberg","year":"1982","unstructured":"Goldberg DB, Schanzlin DJ, Brown SI . Incidence of increased intraocular pressure after keratoplasty. Am J Ophthalmol 1982; 92: 372\u2013377.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2008305_CR30","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S0039-6257(00)00141-7","volume":"45","author":"RS Ayyala","year":"2000","unstructured":"Ayyala RS . Penetrating keratoplasty and glaucoma. Surv Ophthalmol 2000; 45: 91\u2013105.","journal-title":"Surv Ophthalmol"},{"key":"BFeye2008305_CR31","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/0002-9394(69)94577-2","volume":"68","author":"AR Irvine","year":"1969","unstructured":"Irvine AR, Kaufman HE . Intraocular pressure following penetrating keratoplasty. Am J Ophthalmol 1969; 68: 835\u2013844.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2008305_CR32","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1016\/S0161-6420(87)33542-0","volume":"94","author":"GN Foulks","year":"1987","unstructured":"Foulks GN . Glaucoma associated with penetrating keratoplasty. Ophthalmology 1987; 94: 871\u2013874.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR33","first-page":"701","volume":"11","author":"FM Polack","year":"1980","unstructured":"Polack FM . Keratoplasty in aphakic eyes with corneal edema: results in 100 cases with 10-year follow-up. Ophthalmic Surg 1980; 11: 701\u2013707.","journal-title":"Ophthalmic Surg"},{"key":"BFeye2008305_CR34","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1097\/00003226-199209000-00012","volume":"11","author":"CM Kirkness","year":"1992","unstructured":"Kirkness CM, Ficker CA . Risk factors for the development of postkeratoplasty glaucoma. Cornea 1992; 11: 427\u2013432.","journal-title":"Cornea"},{"key":"BFeye2008305_CR35","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/S0161-6420(97)30282-6","volume":"104","author":"CS Siganos","year":"1997","unstructured":"Siganos CS, Solomon A, Frucht-Pery J . Microbial findings in suture erosion after penetrating keratoplasty. Ophthalmology 1997; 104: 513\u2013516.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR36","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1016\/S0161-6420(88)33008-3","volume":"95","author":"DJ Harris","year":"1988","unstructured":"Harris DJ, Stulting RD, Waring III GO, Wilson LA . Late bacterial and fungal keratitis after corneal transplantation. Spectrum of pathogens, graft survival and visual prognosis. Ophthalmology 1988; 95: 1450\u20131457.","journal-title":"Ophthalmology"},{"key":"BFeye2008305_CR37","first-page":"356","volume":"25","author":"H Tavakkoli","year":"1994","unstructured":"Tavakkoli H, Sugar J . Microbial keratitis following penetrating keratoplasty. Ophthalmic Surg 1994; 25: 356\u2013360.","journal-title":"Ophthalmic Surg"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/eye2008305.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye2008305","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye2008305.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T17:05:41Z","timestamp":1684429541000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/eye2008305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,24]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["BFeye2008305"],"URL":"https:\/\/doi.org\/10.1038\/eye.2008.305","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,24]]}}}