{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T21:46:04Z","timestamp":1787262364543,"version":"build-2736575974"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T00:00:00Z","timestamp":1269561600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1038\/eye.2010.34","type":"journal-article","created":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T10:48:37Z","timestamp":1269600517000},"page":"1352-1358","source":"Crossref","is-referenced-by-count":44,"title":["Is cataract associated with cardiovascular morbidity?"],"prefix":"10.1038","volume":"24","author":[{"given":"A Y","family":"Nemet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Vinker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Levartovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Kaiserman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,3,26]]},"reference":[{"key":"BFeye201034_CR1","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1093\/oxfordjournals.epirev.a036197","volume":"17","author":"WG Hodge","year":"1995","unstructured":"Hodge WG, Whitcher JP, Satariano W . Risk factors for age-related cataracts. Epidemiol Rev 1995; 17: 336\u2013346.","journal-title":"Epidemiol Rev"},{"key":"BFeye201034_CR2","first-page":"221","volume":"46","author":"SN Ughade","year":"1998","unstructured":"Ughade SN, Zodpey SP, Khanolkar VA . Risk factors for cataract: a case control study. Indian J Ophthalmol 1998; 46: 221\u2013227.","journal-title":"Indian J Ophthalmol"},{"key":"BFeye201034_CR3","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1093\/aje\/153.9.875","volume":"153","author":"FB Hu","year":"2001","unstructured":"Hu FB, Hankinson SE, Stampfer MJ, Manson JE, Colditz GA, Speizer FE et al. Prospective study of cataract extraction and risk of coronary heart disease in women. Am J Epidemiol 2001; 153: 875\u2013881.","journal-title":"Am J Epidemiol"},{"key":"BFeye201034_CR4","doi-asserted-by":"publisher","first-page":"335S","DOI":"10.1093\/ajcn\/53.1.335S","volume":"53","author":"SD Varma","year":"1991","unstructured":"Varma SD . Scientific basis for medical therapy of cataracts by antioxidants. Am J Clin Nutr 1991; 53: 335S\u2013345S.","journal-title":"Am J Clin Nutr"},{"key":"BFeye201034_CR5","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1076\/opep.6.4.279.4188","volume":"6","author":"ME Goodrich","year":"1999","unstructured":"Goodrich ME, Cumming RG, Mitchell P, Koutts J, Burnett L . Plasma fibrinogen and other cardiovascular disease risk factors and cataract. Ophthalmic Epidemiol 1999; 6: 279\u2013290.","journal-title":"Ophthalmic Epidemiol"},{"key":"BFeye201034_CR6","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1001\/archinte.1989.00390020016004","volume":"149","author":"R Klein","year":"1989","unstructured":"Klein R, Moss SE, Klein BE, DeMets DL . Relation of ocular and systemic factors to survival in diabetes. Arch Intern Med 1989; 149: 266\u2013272.","journal-title":"Arch Intern Med"},{"key":"BFeye201034_CR7","first-page":"404","volume":"3","author":"G Rennert","year":"2001","unstructured":"Rennert G, Peterburg Y . Prevalence of selected chronic diseases in Israel. Isr Med Assoc J 2001; 3: 404\u2013408.","journal-title":"Isr Med Assoc J"},{"key":"BFeye201034_CR8","doi-asserted-by":"publisher","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","volume":"289","author":"AV Chobanian","year":"2003","unstructured":"Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560\u20132572.","journal-title":"JAMA"},{"key":"BFeye201034_CR9","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1016\/S0195-668X(03)00114-3","volume":"24","author":"RM Conroy","year":"2003","unstructured":"Conroy RM, Pyorala K, Fitzgerald AP . Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003; 24: 987\u20131003.","journal-title":"Eur Heart J"},{"key":"BFeye201034_CR10","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S","volume":"15","author":"KG Alberti","year":"1998","unstructured":"Alberti KG, Zimmet PZ . Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998; 15: 539\u2013553.","journal-title":"Diabet Med"},{"key":"BFeye201034_CR11","first-page":"984","volume":"51","author":"G Louridas","year":"2005","unstructured":"Louridas G, Junaid A . Management of carotid artery stenosis. Update for family physicians. Can Fam Physician 2005; 51: 984\u2013989.","journal-title":"Can Fam Physician"},{"key":"BFeye201034_CR12","first-page":"499","volume":"21","author":"R Fontaine","year":"1954","unstructured":"Fontaine R, Kim M, Kieny R . [Surgical treatment of peripheral circulation disorders.]. Helv Chir Acta 1954; 21: 499\u2013533.","journal-title":"Helv Chir Acta"},{"key":"BFeye201034_CR13","doi-asserted-by":"publisher","first-page":"2034","DOI":"10.1681\/ASN.2005101085","volume":"17","author":"M Tonelli","year":"2006","unstructured":"Tonelli M, Wiebe N, Culleton B, House A, Rabbat C, Fok M et al. Chronic kidney disease and mortality risk: a systematic review. J Am Soc Nephrol 2006; 17: 2034\u20132047.","journal-title":"J Am Soc Nephrol"},{"key":"BFeye201034_CR14","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1016\/S0002-9394(99)00218-4","volume":"128","author":"CA McCarty","year":"1999","unstructured":"McCarty CA, Mukesh BN, Fu CL, Taylor HR . The epidemiology of cataract in Australia. Am J Ophthalmol 1999; 128: 446\u2013465.","journal-title":"Am J Ophthalmol"},{"key":"BFeye201034_CR15","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1016\/j.ophtha.2008.04.004","volume":"115","author":"BE Lindblad","year":"2008","unstructured":"Lindblad BE, H\u00e5kansson N, Philipson B, Wolk A . Metabolic syndrome components in relation to risk of cataract extraction: a Prospective Cohort Study of Women. Ophthalmology 2008; 115: 1687\u20131692.","journal-title":"Ophthalmology"},{"key":"BFeye201034_CR16","first-page":"2026","volume":"33","author":"WG Christen","year":"1992","unstructured":"Christen WG, Glynn RJ, Seddon JM . Cataract and subsequent risk of cardiovascular disease (Abstract). Invest Ophthalmol Vis Sci 1992; 33: 2026.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye201034_CR17","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1152\/ajplegacy.1955.180.3.495","volume":"180","author":"JW Patterson","year":"1955","unstructured":"Patterson JW . Effect of blood supply on the development of cataracts. Am J Physiol 1955; 180: 495\u2013497.","journal-title":"Am J Physiol"},{"key":"BFeye201034_CR18","doi-asserted-by":"publisher","first-page":"1478","DOI":"10.1136\/bjo.87.12.1478","volume":"87","author":"Y Barkana","year":"2003","unstructured":"Barkana Y, Harris A, Hefez L, Zaritski M, Chen D, Avni I . Unrecordable pulsatile ocular blood flow may signify severe stenosis of the ipsilateral internal carotid artery. Br J Ophthalmol 2003; 87: 1478\u20131480.","journal-title":"Br J Ophthalmol"},{"key":"BFeye201034_CR19","first-page":"415","volume":"19","author":"AG Abraham","year":"2006","unstructured":"Abraham AG, Condon NG, West Gower E . The new epidemiology of cataract. Ophthalmol Clin North Am 2006; 19: 415\u2013425.","journal-title":"Ophthalmol Clin North Am"},{"key":"BFeye201034_CR20","first-page":"99","volume":"74","author":"SS DeBlack","year":"2003","unstructured":"DeBlack SS . Cigarette smoking as a risk factor for cataract and age-related macular degeneration: a review of the literature. Optometry 2003; 74: 99\u2013110.","journal-title":"Optometry"},{"key":"BFeye201034_CR21","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1001\/archopht.122.4.525","volume":"122","author":"A Hennis","year":"2004","unstructured":"Hennis A, Wu SY, Nemesure B, Leske MC . Risk factors for incident cortical and posterior subcapsular lens opacities in the Barbados Eye Studies. Arch Ophthalmol 2004; 122: 525\u2013530.","journal-title":"Arch Ophthalmol"},{"key":"BFeye201034_CR22","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0161-6420(99)90003-9","volume":"106","author":"MC Leske","year":"1999","unstructured":"Leske MC, Wu SY, Hennis A, Connell AM, Hyman L, Schachat A . Diabetes, hypertension, and central obesity as cataract risk factors in a black population. The Barbados Eye Study. Ophthalmology 1999; 106: 35\u201341.","journal-title":"Ophthalmology"},{"key":"BFeye201034_CR23","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1097\/00004397-200010000-00005","volume":"40","author":"JR Trevithick","year":"2000","unstructured":"Trevithick JR, Mitton KP . Vitamin C and E in cataract risk reduction. Int Ophthalmol Clin 2000; 40: 59\u201369.","journal-title":"Int Ophthalmol Clin"},{"key":"BFeye201034_CR24","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1126\/science.1355616","volume":"257","author":"ER Stadtman","year":"1992","unstructured":"Stadtman ER . Protein oxidation and aging. Science 1992; 257: 1220\u20131224.","journal-title":"Science"},{"key":"BFeye201034_CR25","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1016\/S0002-9394(98)00280-3","volume":"126","author":"BE Klein","year":"1998","unstructured":"Klein BE, Klein R, Lee KE . Diabetes, cardiovascular disease, selected cardiovascular disease risk factors, and the 5-year incidence of age-related cataract and progression of lens opacities: the Beaver Dam Eye study. Am J Ophthalmol 1998; 126: 782\u2013790.","journal-title":"Am J Ophthalmol"},{"key":"BFeye201034_CR26","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1001\/jama.286.3.327","volume":"286","author":"AD Pradhan","year":"2001","unstructured":"Pradhan AD, Manson JE, Buring JE, Rifai N, Ridker PM. . C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001; 286: 327\u2013334.","journal-title":"JAMA"},{"key":"BFeye201034_CR27","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/S0161-6420(02)01762-1","volume":"110","author":"R Hiller","year":"2003","unstructured":"Hiller R, Sperduto RD, Reed GF, D\u2019Agostino RB, Wilson PW . Serum lipids and age-related lens opacities: a longitudinal investigation: the Framingham Studies. Ophthalmology 2003; 110: 578\u2013583.","journal-title":"Ophthalmology"},{"key":"BFeye201034_CR28","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1093\/aje\/kwi118","volume":"161","author":"M Lu","year":"2005","unstructured":"Lu M, Cho E, Taylor A, Hankinson SE, Willett WC, Jacques PF . Prospective study of dietary fat and risk of cataract extraction among US women. Am J Epidemiol 2005; 161: 948\u2013959.","journal-title":"Am J Epidemiol"},{"key":"BFeye201034_CR29","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1248\/bpb.22.37","volume":"22","author":"K Tsutsumi","year":"1999","unstructured":"Tsutsumi K, Inoue Y, Yoshida C . Acceleration of development of diabetic cataract by hyperlipidemia and low high-density lipoprotein in rats. Biol Pharm Bull 1999; 22: 37\u201341.","journal-title":"Biol Pharm Bull"},{"key":"BFeye201034_CR30","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/1047-2797(94)00111-6","volume":"5","author":"A Tavani","year":"1995","unstructured":"Tavani A, Negri E, La Vecchia C . Selected diseases and risk of cataracts in women: a case-control study from northern Italy. Ann Epidemiol 1995; 5: 234\u2013238.","journal-title":"Ann Epidemiol"},{"key":"BFeye201034_CR31","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/S1047-2797(00)00178-2","volume":"11","author":"DA Schaumberg","year":"2001","unstructured":"Schaumberg DA, Glynn RJ, Christen WG, Ajani UA, St\u00fcrmer T, Hennekens CH . A prospective study of blood pressure and risk of cataract in men. Ann Epidemiol 2001; 11: 104\u2013110.","journal-title":"Ann Epidemiol"},{"key":"BFeye201034_CR32","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1159\/000060807","volume":"35","author":"CA McCarty","year":"2002","unstructured":"McCarty CA, Taylor HR . A review of the epidemiologic evidence linking ultraviolet radiation and cataracts. Dev Ophthalmol 2002; 35: 21\u201331.","journal-title":"Dev Ophthalmol"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/eye201034.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye201034","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye201034.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T17:12:10Z","timestamp":1684429930000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/eye201034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,26]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["BFeye201034"],"URL":"https:\/\/doi.org\/10.1038\/eye.2010.34","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,26]]}}}