{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T18:53:04Z","timestamp":1790103184209,"version":"4.0.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T00:00:00Z","timestamp":1377216000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1038\/eye.2013.187","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T09:49:25Z","timestamp":1377251365000},"page":"1293-1298","source":"Crossref","is-referenced-by-count":97,"title":["Eye drop instillation technique in patients with glaucoma"],"prefix":"10.1038","volume":"27","author":[{"given":"A J","family":"Tatham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U","family":"Sarodia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Gatrad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Awan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,8,23]]},"reference":[{"key":"BFeye2013187_CR1","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/0002-9394(86)90939-6","volume":"101","author":"MA Kass","year":"1986","unstructured":"Kass MA, Meltzer DW, Gordon M, Cooper D, Goldberg J . Compliance with topical pilocarpine treatment. Am J Ophthalmol 1986; 101: 515\u2013523.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2013187_CR2","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1136\/bjo.74.8.477","volume":"74","author":"AJ Winfield","year":"1990","unstructured":"Winfield AJ, Jessiman D, Williams A, Esakowitz L . A study of the causes of non-compliance by patients prescribed eyedrops. Br J Ophthalmol 1990; 74: 477\u2013480.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2013187_CR3","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1136\/bjo.66.7.464","volume":"66","author":"PA Granstr\u00f6m","year":"1982","unstructured":"Granstr\u00f6m PA . Glaucoma patients not compliant with their drug therapy: clinical and behavioural aspects. Br J Ophthalmol 1982; 66: 464\u2013470.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2013187_CR4","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.ajo.2010.05.005","volume":"150","author":"VH Lu","year":"2010","unstructured":"Lu VH, Goldberg I, Lu CY . Use of glaucoma medications: state of the science and directions for observational research. Am J Ophthalmol 2010; 150: 569\u2013574.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2013187_CR5","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1097\/IJG.0b013e31819c4679","volume":"19","author":"JE Stryker","year":"2010","unstructured":"Stryker JE, Beck AD, Primo SA, Echt KV, Bundy L, Pretorius GC et al. An exploratory study of factors influencing glaucoma treatment adherence. J Glaucoma 2010; 19: 66\u201372.","journal-title":"J Glaucoma"},{"key":"BFeye2013187_CR6","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1097\/00061198-200310000-00001","volume":"12","author":"JC Tsai","year":"2003","unstructured":"Tsai JC, McClure CA, Ramos SE, Schlundt DG, Pichert JW . Compliance barriers in glaucoma: a systematic classification. J Glaucoma. 2003; 12: 393\u2013398.","journal-title":"J Glaucoma."},{"key":"BFeye2013187_CR7","doi-asserted-by":"publisher","first-page":"2398","DOI":"10.1016\/j.ophtha.2011.05.013","volume":"118","author":"B Sleath","year":"2011","unstructured":"Sleath B, Blalock S, Covert D, Stone JL, Skinner AC, Muir K et al. The relationship between glaucoma medication adherence, eye drop technique, and visual field defect severity. Ophthalmology 2011; 118: 2398\u20132402.","journal-title":"Ophthalmology"},{"key":"BFeye2013187_CR8","first-page":"775","volume":"14","author":"MA Kass","year":"1982","unstructured":"Kass MA, Hodapp E, Gordon M, Kolker AE, Goldberg I . Part I. Patient administration of eyedrops: interview. Ann Ophthalmol 1982; 14: 775\u2013779.","journal-title":"Ann Ophthalmol"},{"key":"BFeye2013187_CR9","first-page":"457","volume":"74","author":"FT Fraunfelder","year":"1976","unstructured":"Fraunfelder FT . Extraocular fluid dynamics: how best to apply topical ocular medication. Trans Am Ophthalmol Soc 1976; 74: 457\u2013487.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"BFeye2013187_CR10","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1001\/archopht.1984.01040030429017","volume":"102","author":"TJ Zimmerman","year":"1984","unstructured":"Zimmerman TJ, Kooner KS, Kandarakis AS, Ziegler LP . Improving the therapeutic index of topically applied ocular drugs. Arch Ophthalmol 1984; 102: 551\u2013553.","journal-title":"Arch Ophthalmol"},{"key":"BFeye2013187_CR11","first-page":"29","volume":"105","author":"T Tsai","year":"2007","unstructured":"Tsai T, Robin AL, Smith JP III . An evaluation of how glaucoma patients use topical medications: a pilot study. Trans Am Ophthalmol Soc 2007; 105: 29\u201335.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"BFeye2013187_CR12","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1136\/bjo.79.4.376","volume":"79","author":"O Geyer","year":"1995","unstructured":"Geyer O, Bottone EJ, Podos SM, Schumer RA, Asbell PA . Microbial contamination of medications used to treat glaucoma. Br J Ophthalmol 1995; 79: 376\u2013379.","journal-title":"Br J Ophthalmol"},{"key":"BFeye2013187_CR13","first-page":"2","volume":"19","author":"MM Brown","year":"1984","unstructured":"Brown MM, Brown GC, Spaeth GL . Improper topical self-administration of ocular medication among patients with glaucoma. Can J Ophthalmol 1984; 19: 2\u20135.","journal-title":"Can J Ophthalmol"},{"key":"BFeye2013187_CR14","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1097\/IJG.0b013e31820bd2e1","volume":"21","author":"R Gupta","year":"2012","unstructured":"Gupta R, Patil B, Shah BM, Bali SJ, Mishra SK, Dada T . Evaluating eye drop instillation technique in glaucoma patients. J Glaucoma 2012; 21: 189\u2013192.","journal-title":"J Glaucoma"},{"key":"BFeye2013187_CR15","doi-asserted-by":"publisher","first-page":"454","DOI":"10.3129\/i08-076","volume":"43","author":"R Kholdebarin","year":"2008","unstructured":"Kholdebarin R, Campbell RJ, Jin YP, Buys YM . Multicenter study of compliance and drop administration in glaucoma. Can J Ophthalmol 2008; 43: 454\u2013461.","journal-title":"Can J Ophthalmol"},{"key":"BFeye2013187_CR16","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1111\/j.1755-3768.2007.01155.x","volume":"86","author":"TS Dietlein","year":"2008","unstructured":"Dietlein TS, Jordan JF, L\u00fcke C, Schild A, Dinslage S, Krieglstein GK . Self-application of single-use eyedrop containers in an elderly population: comparisons with standard eyedrop bottle and with younger patients. Acta Ophthalmol 2008; 86: 856\u2013859.","journal-title":"Acta Ophthalmol"},{"key":"BFeye2013187_CR17","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1037\/h0026256","volume":"70","author":"J Cohen","year":"1968","unstructured":"Cohen J . Weighted kappa: nominal scale agreement provision for scaled disagreement or partial credit. Psychol Bull 1968; 70: 213\u2013220.","journal-title":"Psychol Bull"},{"key":"BFeye2013187_CR18","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG . The measurement of observer agreement for categorical data. Biometrics 1977; 33: 159\u2013174.","journal-title":"Biometrics"},{"key":"BFeye2013187_CR19","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1136\/bjo.2008.144469","volume":"92","author":"MS Kim","year":"2008","unstructured":"Kim MS, Choi CY, Kim JM, Woo HY . Microbial contamination of multiply used preservative-free artificial tears packed in reclosable containers. Br J Ophthalmol 2008; 92: 1518\u20131521.","journal-title":"Br J Ophthalmol"},{"issue":"105","key":"BFeye2013187_CR20","first-page":"361","volume":"15","author":"OD Schein","year":"1988","unstructured":"Schein OD, Wasson PJ, Boruchoff SA, Kenyon KR . Microbial keratitis associated with contaminated ocular medications. Am J Ophthalmol 1988; 15 (105): 361\u2013365.","journal-title":"Am J Ophthalmol"},{"key":"BFeye2013187_CR21","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1001\/archophthalmol.2009.96","volume":"127","author":"JL Stone","year":"2009","unstructured":"Stone JL, Robin AL, Novack GD, Covert DW, Cagle GD . An objective evaluation of eyedrop instillation in patients with glaucoma. Arch Ophthalmol 2009; 127: 732\u2013736.","journal-title":"Arch Ophthalmol"},{"key":"BFeye2013187_CR22","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1177\/112067210901900609","volume":"19","author":"JP Nordmann","year":"2009","unstructured":"Nordmann JP, Baudouin C, Bron A, Denis P, Rouland JF, Sellem E et al. Xal-Ease: impact of an ocular hypotensive delivery device on ease of eyedrop administration, patient compliance, and satisfaction. Eur J Ophthalmol 2009; 19: 949\u2013956.","journal-title":"Eur J Ophthalmol"},{"key":"BFeye2013187_CR23","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/S0008-4182(05)80028-6","volume":"40","author":"A Salyani","year":"2005","unstructured":"Salyani A, Birt C . Evaluation of an eye drop guide to aid self-administration by patients experienced with topical use of glaucoma medication. Can J Ophthalmol 2005; 40: 170\u2013174.","journal-title":"Can J Ophthalmol"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/eye2013187.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye2013187","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye2013187.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T17:19:32Z","timestamp":1684430372000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/eye2013187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,23]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["BFeye2013187"],"URL":"https:\/\/doi.org\/10.1038\/eye.2013.187","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,23]]}}}