{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:26:00Z","timestamp":1758122760227},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T00:00:00Z","timestamp":1398988800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1038\/eye.2014.97","type":"journal-article","created":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T09:50:58Z","timestamp":1399024258000},"page":"784-785","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Is accelerated corneal collagen cross-linking for keratoconus the way forward? Yes"],"prefix":"10.1038","volume":"28","author":[{"given":"M","family":"Tsatsos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"MacGregor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Kopsachilis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,5,2]]},"reference":[{"issue":"1","key":"BFeye201497_CR1","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1006\/exer.1997.0410","volume":"66","author":"E Spoerl","year":"1998","unstructured":"Spoerl E, Huhle M, Seiler T . Induction of cross-links in corneal tissue. Exp Eye Res 1998; 66 (1): 97\u2013103.","journal-title":"Exp Eye Res"},{"key":"BFeye201497_CR2","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1007\/s003470050219","volume":"94","author":"E Sporl","year":"1997","unstructured":"Sporl E, Huhle M, Kasper M, Seiler T . Increased rigidity of the cornea caused by intrastromal cross-linking. Ophthalmologe 1997; 94: 902\u2013906.","journal-title":"Ophthalmologe"},{"issue":"5","key":"BFeye201497_CR3","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","volume":"135","author":"G Wollensak","year":"2003","unstructured":"Wollensak G, Spoerl E, Seiler T . Riboflavin\/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003; 135 (5): 620\u2013627.","journal-title":"Am J Ophthalmol"},{"key":"BFeye201497_CR4","first-page":"306","volume":"12","author":"RW Bunsen","year":"1862","unstructured":"Bunsen RW, Roscoe HE . Photochemical researches, part V: on the measurement of the chemical action of direct and diffuse sunlight. Proc R Soc Lond 1862; 12: 306\u2013312.","journal-title":"Proc R Soc Lond"},{"key":"BFeye201497_CR5","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1167\/iovs.12-11409","volume":"54","author":"J Wernli","year":"2013","unstructured":"Wernli J, Schumacher S, Spoerl E, Mrochen M . The efficacy of corneal cross-lining shows sudden decrease with very high intensity UV light and short treatment time. Invest Ophthalmol Vis Sci 2013; 54: 1176\u20131180.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFeye201497_CR6","doi-asserted-by":"publisher","first-page":"9048","DOI":"10.1167\/iovs.11-7818","volume":"52","author":"S Schumacher","year":"2011","unstructured":"Schumacher S, Oeftiger L, Mrochen M . Equivalence of biomechanical changes induced by rapid and standard corneal cross-linking, using riboflavin and ultraviolet radiation. Invest Ophthalmol Vis Sci 2011; 52: 9048\u20139052.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"8","key":"BFeye201497_CR7","doi-asserted-by":"publisher","first-page":"5273","DOI":"10.1167\/iovs.13-12576","volume":"54","author":"IM Beshtawi","year":"2013","unstructured":"Beshtawi IM, Akhtar R, Hillarby MC, O\u2019Donnell C, Zhao X, Brahma A et al. Biomechanical properties of human corneas following low and high-intensity collagen cross-linking determined with scanning acoustic microscopy. Invest Ophthalmol Vis Sci 2013; 54 (8): 5273\u20135280.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"BFeye201497_CR8","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.ajo.2008.05.042","volume":"146","author":"C Mazzotta","year":"2008","unstructured":"Mazzotta C, Traversi C, Baiocchi S, Caporossi O, Bovone C, Sparano MC et al. Corneal healing after riboflavin ultraviolet-A collagen cross-linking determined by confocal laser scanning microscopy in vivo: early and late modifications. Am J Ophthalmol 2008; 146 (4): 527\u2013533.","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"BFeye201497_CR9","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.ajo.2013.09.010","volume":"157","author":"GD Kymionis","year":"2014","unstructured":"Kymionis GD, Crentzelos MA, Plaka AD, Tsoulnaras KI, Diakonis VF, Liakopoulos DA et al. Correlation of the corneal collagen cross-linking demaracation line using confocal microscopy and anterior segment optical coherence tomography in keratoconic patients. Am J Ophthalmol 2014; 157 (1): 110\u2013115.","journal-title":"Am J Ophthalmol"},{"issue":"11","key":"BFeye201497_CR10","doi-asserted-by":"publisher","first-page":"769","DOI":"10.3928\/1081597X-20121016-01","volume":"28","author":"D Touboul","year":"2012","unstructured":"Touboul D, Efron N, Smadia D, Praud D, Malet F, Colin J . Corneal confocal microscopy following conventional transepithelial and accelerated corneal collagen cross-linking procedure for keratoconus. J Refract Surg 2012; 28 (11): 769\u2013776.","journal-title":"J Refract Surg"},{"key":"BFeye201497_CR11","doi-asserted-by":"publisher","first-page":"97","DOI":"10.2147\/OPTH.S27170","volume":"6","author":"AJ Kanellopoulos","year":"2012","unstructured":"Kanellopoulos AJ . Long term results of a prospective randomized bilateral eye comparison trial of higher fluence, shorter duration ultraviolet A radiation, and riboflavin collagen cross linking for progressive keratoconus. Clin Ophthalmol 2012; 6: 97\u2013101.","journal-title":"Clin Ophthalmol"},{"issue":"3","key":"BFeye201497_CR12","doi-asserted-by":"publisher","first-page":"218","DOI":"10.3109\/15569527.2013.834497","volume":"33","author":"Yasin \u00c7\u0131nar","year":"2013","unstructured":"C\u0131nar Y, Cing\u00fc AK, T\u00fcrkc\u00fc FM, C\u0131nar T, Y\u00fcksel H, Ozkurt ZG et al. Comparison of accelerated and conventional corneal collagen cross-linking for progressive keratoconus. Cutan Ocul Toxicol 2013 e-pub ahead of print 22 October 2013 doi:10.3109\/15569527.2013.834497.","journal-title":"Cutaneous and Ocular Toxicology"},{"issue":"12","key":"BFeye201497_CR13","doi-asserted-by":"publisher","first-page":"846","DOI":"10.3928\/1081597X-20131023-03","volume":"29","author":"Z Gatziofas","year":"2013","unstructured":"Gatziofas Z, Richoz O, Brugnoli E, Hafezi F . Safety profile of high fluence corneal collagen cross-linking for progressive keratoconus: preliminary results from a prospective cohort study. J Refract Surg 2013; 29 (12): 846\u2013848.","journal-title":"J Refract Surg"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/eye201497.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye201497","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/eye201497.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T17:24:40Z","timestamp":1684430680000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/eye201497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,2]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["BFeye201497"],"URL":"https:\/\/doi.org\/10.1038\/eye.2014.97","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,2]]},"assertion":[{"value":"2 May 2014","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}