{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:51:07Z","timestamp":1790693467706,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":1479,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["gimjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1038\/gim.2017.104","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T11:08:01Z","timestamp":1500548881000},"page":"142-150","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["A patient with germ-line gain-of-function PDGFRB p.N666H mutation and marked clinical response to imatinib"],"prefix":"10.1016","volume":"20","author":[{"given":"Dinel","family":"Pond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence A.","family":"Arts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy J.","family":"Mendelsohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Baptiste","family":"Demoulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunter","family":"Scharer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoav","family":"Messinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/gim.2017.104_bb0010","author":"Demoulin"},{"key":"10.1038\/gim.2017.104_bb0015","author":"Soriano"},{"key":"10.1038\/gim.2017.104_bb0020","author":"Soriano"},{"key":"10.1038\/gim.2017.104_bb0025","author":"Andrae"},{"key":"10.1038\/gim.2017.104_bb0030","author":"Martignetti"},{"key":"10.1038\/gim.2017.104_bb0035","author":"Cheung"},{"key":"10.1038\/gim.2017.104_bb0040","author":"Linhares"},{"key":"10.1038\/gim.2017.104_bb0045","author":"Bick"},{"key":"10.1038\/gim.2017.104_bb0050","author":"Murray"},{"key":"10.1038\/gim.2017.104_bb0055","author":"Mudry"},{"key":"10.1038\/gim.2017.104_bb0060","author":"Takenouchi"},{"key":"10.1038\/gim.2017.104_bb0065","author":"Johnston"},{"key":"10.1038\/gim.2017.104_bb0070","author":"Arts"},{"key":"10.1038\/gim.2017.104_bb0075","author":"Cheah"},{"key":"10.1038\/gim.2017.104_bb0080","author":"Noujaim"},{"key":"10.1038\/gim.2017.104_bb0085","author":"Roufosse"},{"key":"10.1038\/gim.2017.104_bb0090","first-page":"43","article-title":"Gastrointestinal stromal tumor\u2014an evolving concept","volume":"1","author":"Tornillo","year":"2014","journal-title":"Front Med (Lausanne)"},{"key":"10.1038\/gim.2017.104_bb0095","author":"Farwell"},{"key":"10.1038\/gim.2017.104_bb0100","author":"Richards"},{"key":"10.1038\/gim.2017.104_bb0105","author":"Lennartsson"},{"key":"10.1038\/gim.2017.104_bb0110","author":"Demoulin"},{"key":"10.1038\/gim.2017.104_bb0115","unstructured":"Demoulin JB, Uyttenhove C, Lejeune D, Mui A, Groner B, Renauld JC. STAT5 activation is required for interleukin-9-dependent growth and transformation of lymphoid cells. Cancer Res. 2000;60:3971\u20133977."},{"key":"10.1038\/gim.2017.104_bb0120","author":"Arts"},{"key":"10.1038\/gim.2017.104_bb0125","author":"Arts"},{"key":"10.1038\/gim.2017.104_bb0130","author":"Velghe"},{"key":"10.1038\/gim.2017.104_bb0135","author":"Schonherr"},{"key":"10.1038\/gim.2017.104_bb0140","author":"Nakahara"},{"key":"10.1038\/gim.2017.104_bb0145","author":"Caglayan"},{"key":"10.1038\/gim.2017.104_bb0150","author":"Roche"},{"key":"10.1038\/gim.2017.104_bb0155","author":"Nicolas"},{"key":"10.1038\/gim.2017.104_bb0160","author":"Lasota"},{"key":"10.1038\/gim.2017.104_bb0165","doi-asserted-by":"crossref","unstructured":"Keating MT, Harryman CC, Williams LT. Platelet-derived growth factor receptor inducibility is acquired immediately after translation and does not require glycosylation. J Biol Chem. 1989;264:9129\u20139132.","DOI":"10.1016\/S0021-9258(18)60502-2"}],"container-title":["Genetics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/gim2017104.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/gim2017104","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021019122?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021019122?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/gim.2017.104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/gim2017104.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T01:47:07Z","timestamp":1761097627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098360021019122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S1098360021019122"],"URL":"https:\/\/doi.org\/10.1038\/gim.2017.104","relation":{},"ISSN":["1098-3600"],"issn-type":[{"value":"1098-3600","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A patient with germ-line gain-of-function PDGFRB p.N666H mutation and marked clinical response to imatinib","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/gim.2017.104","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018, The Author(s), under exclusive licence to the American College of Medical Genetics and Genomics","name":"copyright","label":"Copyright"}]}}