{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:47:17Z","timestamp":1791978437395,"version":"4.4.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":1448,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["gimjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1038\/gim.2017.106","type":"journal-article","created":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T11:00:40Z","timestamp":1501153240000},"page":"259-268","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["SLC39A8 deficiency: biochemical correction and major clinical improvement by manganese therapy"],"prefix":"10.1016","volume":"20","author":[{"given":"Julien H.","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Hogrebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Fobker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Brackmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Fiedler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Reunert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Rust","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Tsiakas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Santer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Gr\u00fcneberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Marquardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/gim.2017.106_bb0010","author":"Park"},{"key":"10.1038\/gim.2017.106_bb0015","author":"Boycott"},{"key":"10.1038\/gim.2017.106_bb0020","author":"Chen"},{"key":"10.1038\/gim.2017.106_bb0025","author":"Leach"},{"key":"10.1038\/gim.2017.106_bb0030","author":"Avila"},{"key":"10.1038\/gim.2017.106_bb0035","author":"Powell"},{"key":"10.1038\/gim.2017.106_bb0040","author":"Kuhn"},{"key":"10.1038\/gim.2017.106_bb0045","author":"Ng"},{"key":"10.1038\/gim.2017.106_bb0050","author":"Dorre"},{"key":"10.1038\/gim.2017.106_bb0055","series-title":"Modern Nutrition in Health and Disease","author":"Ross","year":"2014"},{"key":"10.1038\/gim.2017.106_bb0060","author":"Achouitar"},{"key":"10.1038\/gim.2017.106_bb0065","doi-asserted-by":"crossref","unstructured":"Fran\u011bk T, Kota\u0161ka K, Pr\u016f\u0161a R. Manganese and selenium concentrations in cerebrospinal fluid of seriously ill children. J Clin Lab Anal; e-pub ahead of print 15 February 2017.","DOI":"10.1002\/jcla.22122"},{"key":"10.1038\/gim.2017.106_bb0070","doi-asserted-by":"crossref","unstructured":"Friedman BJ, Freeland-Graves JH, Bales CW et al. Manganese balance and clinical observations in young men fed a manganese-deficient diet. 1987;117:133\u2013143.","DOI":"10.1093\/jn\/117.1.133"},{"key":"10.1038\/gim.2017.106_bb0075","author":"Nelson"},{"key":"10.1038\/gim.2017.106_bb0080","author":"Crossgrove"},{"key":"10.1038\/gim.2017.106_bb0085","author":"Tuschl"},{"key":"10.1038\/gim.2017.106_bb0090","author":"Riley"},{"key":"10.1038\/gim.2017.106_bb0095","author":"Niehues"},{"key":"10.1038\/gim.2017.106_bb0100","author":"Liem"},{"key":"10.1038\/gim.2017.106_bb0105","author":"Marquardt"},{"key":"10.1038\/gim.2017.106_bb0110","author":"Etzioni"},{"key":"10.1038\/gim.2017.106_bb0115","author":"Wild"},{"key":"10.1038\/gim.2017.106_bb0120","author":"Tegtmeyer"},{"key":"10.1038\/gim.2017.106_bb0125","author":"Schrapers"},{"key":"10.1038\/gim.2017.106_bb0130","author":"Bornhorst"},{"key":"10.1038\/gim.2017.106_bb0135","author":"Aschner"},{"key":"10.1038\/gim.2017.106_bb0140","author":"Crossgrove"},{"key":"10.1038\/gim.2017.106_bb0145","author":"Michalke"},{"key":"10.1038\/gim.2017.106_bb0150","author":"Horning"},{"key":"10.1038\/gim.2017.106_bb0155","author":"Zeevaert"},{"key":"10.1038\/gim.2017.106_bb0160","author":"Foulquier"},{"key":"10.1038\/gim.2017.106_bb0165","author":"Schulte Althoff"},{"key":"10.1038\/gim.2017.106_bb0170","author":"Potelle"},{"key":"10.1038\/gim.2017.106_bb0175","author":"Tuschl"},{"key":"10.1038\/gim.2017.106_bb0180","author":"Klos"},{"key":"10.1038\/gim.2017.106_bb0185","author":"Aschner"},{"key":"10.1038\/gim.2017.106_bb0190","author":"Uhl\u00e9n"},{"key":"10.1038\/gim.2017.106_bb0195","author":"Fujishiro"}],"container-title":["Genetics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/gim2017106.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/gim2017106","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021018967?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021018967?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/gim.2017.106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/gim2017106.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T01:47:14Z","timestamp":1761097634000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098360021018967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S1098360021018967"],"URL":"https:\/\/doi.org\/10.1038\/gim.2017.106","relation":{},"ISSN":["1098-3600"],"issn-type":[{"value":"1098-3600","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SLC39A8 deficiency: biochemical correction and major clinical improvement by manganese therapy","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/gim.2017.106","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018, The Author(s), under exclusive licence to the American College of Medical Genetics and Genomics","name":"copyright","label":"Copyright"}]}}