{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:45:19Z","timestamp":1790401519076,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":1328,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["gimjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1038\/gim.2017.154","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T11:11:38Z","timestamp":1507806698000},"page":"599-607","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Noncoding copy-number variations are associated with congenital limb malformation"],"prefix":"10.1016","volume":"20","author":[{"given":"Ricarda","family":"Fl\u00f6ttmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rt K.","family":"Kragesteen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinje","family":"Geuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Socha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lila","family":"Allou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Sowi\u0144ska-Seidler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Bosquillon de Jarcy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksander","family":"Jamsheer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Oehl-Jaschkowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Wittler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepthi","family":"de Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Kurth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idit","family":"Maya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Santos-Simarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebke","family":"H\u00fclsemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Klopocki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Mountford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Fryer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guntram","family":"Borck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Horn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Lapunzina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9n\u00e9dicte","family":"Mascrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Duboule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Mundlos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malte","family":"Spielmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/gim.2017.154_bb0010","author":"Albers"},{"key":"10.1038\/gim.2017.154_bb0015","author":"Petit"},{"key":"10.1038\/gim.2017.154_bb0020","author":"Lupianez"},{"key":"10.1038\/gim.2017.154_bb0025","author":"Spielmann"},{"key":"10.1038\/gim.2017.154_bb0030","author":"Spielmann"},{"key":"10.1038\/gim.2017.154_bb0035","author":"Dathe"},{"key":"10.1038\/gim.2017.154_bb0040","author":"Franke"},{"key":"10.1038\/gim.2017.154_bb0045","author":"Benko"},{"key":"10.1038\/gim.2017.154_bb0050","author":"Fernandez"},{"key":"10.1038\/gim.2017.154_bb0055","author":"Dixon"},{"key":"10.1038\/gim.2017.154_bb0060","author":"Lieberman-Aiden"},{"key":"10.1038\/gim.2017.154_bb0065","author":"Van Bortle"},{"key":"10.1038\/gim.2017.154_bb0070","author":"Hnisz"},{"key":"10.1038\/gim.2017.154_bb0075","author":"Lupianez"},{"key":"10.1038\/gim.2017.154_bb0080","author":"Gilissen"},{"key":"10.1038\/gim.2017.154_bb0085","author":"Cooper"},{"key":"10.1038\/gim.2017.154_bb0090","unstructured":"Kraft K, Geuer S, Will AJ et al. Deletions, inversions, duplications: engineering of structural variants using CRISPR\/Cas in mice. Cell Rep 2015; e-pub ahead of print 4 February 2015."},{"key":"10.1038\/gim.2017.154_bb0095","author":"Montavon"},{"key":"10.1038\/gim.2017.154_bb0100","author":"Artus"},{"key":"10.1038\/gim.2017.154_bb0105","author":"Albrecht"},{"key":"10.1038\/gim.2017.154_bb0110","author":"Firth"},{"key":"10.1038\/gim.2017.154_bb0115","author":"Landrum"},{"key":"10.1038\/gim.2017.154_bb0120","author":"Visel"},{"key":"10.1038\/gim.2017.154_bb0125","author":"Cotney"},{"key":"10.1038\/gim.2017.154_bb0130","author":"Kohler"},{"key":"10.1038\/gim.2017.154_bb0135","author":"Robinson"},{"key":"10.1038\/gim.2017.154_bb0140","author":"Mouse Genome Database Group"},{"key":"10.1038\/gim.2017.154_bb0145","author":"Smith"},{"key":"10.1038\/gim.2017.154_bb0150","author":"Visel"},{"key":"10.1038\/gim.2017.154_bb0155","author":"VanderMeer"},{"key":"10.1038\/gim.2017.154_bb0160","author":"Rao"},{"key":"10.1038\/gim.2017.154_bb0165","author":"Klopocki"},{"key":"10.1038\/gim.2017.154_bb0170","author":"Malik"},{"key":"10.1038\/gim.2017.154_bb0175","author":"Nevado"},{"key":"10.1038\/gim.2017.154_bb0180","author":"Eppig"},{"key":"10.1038\/gim.2017.154_bb0185","author":"Symmons"},{"key":"10.1038\/gim.2017.154_bb0190","author":"Dickinson"},{"key":"10.1038\/gim.2017.154_bb0195","author":"Ibn-Salem"},{"key":"10.1038\/gim.2017.154_bb0200","author":"Kleinjan"},{"key":"10.1038\/gim.2017.154_bb0205","author":"Talkowski"},{"key":"10.1038\/gim.2017.154_bb0210","author":"Walker"},{"key":"10.1038\/gim.2017.154_bb0215","author":"Sanna-Cherchi"},{"key":"10.1038\/gim.2017.154_bb0220","author":"Spielmann"}],"container-title":["Genetics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/gim2017154.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/gim2017154","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021009989?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021009989?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/gim.2017.154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/gim2017154.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T01:47:38Z","timestamp":1761097658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098360021009989"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S1098360021009989"],"URL":"https:\/\/doi.org\/10.1038\/gim.2017.154","relation":{},"ISSN":["1098-3600"],"issn-type":[{"value":"1098-3600","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Noncoding copy-number variations are associated with congenital limb malformation","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/gim.2017.154","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018, The Author(s), under exclusive licence to the American College of Medical Genetics and Genomics","name":"copyright","label":"Copyright"}]}}