{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:19:51Z","timestamp":1788970791408,"version":"build-2803163510"},"reference-count":31,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":1175,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["gimjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1038\/gim.2018.13","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T10:45:56Z","timestamp":1520505956000},"page":"1462-1467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["\u201cWell, good luck with that\u201d: reactions to learning of increased genetic risk for Alzheimer disease"],"prefix":"10.1016","volume":"20","author":[{"given":"Doris T.","family":"Zallen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/gim.2018.13_bb0010","author":"Corder"},{"key":"10.1038\/gim.2018.13_bb0015","author":"Breitner"},{"key":"10.1038\/gim.2018.13_bb0020","author":"Christensen"},{"key":"10.1038\/gim.2018.13_bb0025","author":"Seshadri"},{"key":"10.1038\/gim.2018.13_bb0030","unstructured":"Bird TDAlzheimer disease overview. In: Pagon RA, Adam MP, Ardinger HH et al(eds). GeneReviews. University of Washington: Seattle, WA, 23 October 1998. Updated 24 September 2015."},{"key":"10.1038\/gim.2018.13_bb0035","author":"American College of Medical Genetics, American Society of Human Genetics Working Group on ApoE and Alzheimer Disease"},{"key":"10.1038\/gim.2018.13_bb0040","author":"Medical and Scientific Advisory Committee and Alzheimer\u2019s Disease International"},{"key":"10.1038\/gim.2018.13_bb0045","author":"National Institute on Aging and Alzheimer\u2019s Association Working Group"},{"key":"10.1038\/gim.2018.13_bb0050","unstructured":"Choosing Wisely. ACMG Provides Recommendations on Genetic Testing Through the Choosing Wisely\u00ae Campaign. http:\/\/www.choosingwisely.org\/acmg-provides-recommendations-on-genetic-testing-through-the-choosing-wisely-campaign\/. 10 July 2015. Accessed 12 January 2018."},{"key":"10.1038\/gim.2018.13_bb0055","author":"Grosse"},{"key":"10.1038\/gim.2018.13_bb0060","series-title":"To Test or Not to Test: A Consumer\u2019s Guide to Genetic Screening and Risk","first-page":"73","author":"Zallen","year":"2008"},{"key":"10.1038\/gim.2018.13_bb0065","author":"Green"},{"key":"10.1038\/gim.2018.13_bb0070","author":"Roberts"},{"key":"10.1038\/gim.2018.13_bb0075","author":"Hyejin"},{"key":"10.1038\/gim.2018.13_bb0080","author":"Neergaard"},{"key":"10.1038\/gim.2018.13_bb0085","author":"Huynh"},{"key":"10.1038\/gim.2018.13_bb0090","author":"Eckert"},{"key":"10.1038\/gim.2018.13_bb0095","author":"Lock"},{"key":"10.1038\/gim.2018.13_bb0100","unstructured":"National Society of Genetic Counselors, Genetic testing of minors for adult-onset conditions. 15 February 2017. https:\/\/www.nsgc.org\/p\/bl\/et\/blogaid=860. Accessed 12 January 2018."},{"key":"10.1038\/gim.2018.13_bb0105","unstructured":"Re\/code Decode hosted by Kara Swisher. Interview with Anne Wojcicki released 3 April 2016. https:\/\/itunes.apple.com\/us\/podcast\/re-code-decode-hosted-by-kara\/id1011668648?mt=2#episodeGuid=gid%3A%2F%2Fart19-episode-locator%2FV0%2FXjMqFQjIEjXmQTYNq_1kLNl8CPNiyo-to7ChjXCLSdA Accessed 12 January 2018."},{"key":"10.1038\/gim.2018.13_bb0110","unstructured":"US Food and Drug Administration. FDA allows marketing of first direct-to-consumer tests that provide genetic risk information for certain conditions. 6 April 6 2017. https:\/\/www.fda.gov\/NewsEvents\/Newsroom\/PressAnnouncements\/ucm551185.htm Accessed 12 January 2018."},{"key":"10.1038\/gim.2018.13_bb0115","author":"Quaid"},{"key":"10.1038\/gim.2018.13_bb0120","series-title":"Does it Run in the Family? A Consumer\u2019s Guide to DNA Testing for Genetic Disorders","author":"Zallen","year":"2008"},{"key":"10.1038\/gim.2018.13_bb0125","unstructured":"Huntington\u2019s Disease Society of America. Genetic testing protocol for Huntington\u2019s disease. 2016. http:\/\/hdsa.org\/wp-content\/uploads\/2015\/02\/HDSA-Gen-Testing-Protocol-for-HD.pdf. Accessed 12 January 2018."},{"key":"10.1038\/gim.2018.13_bb0130","author":"American Society of Clinical Oncology"},{"key":"10.1038\/gim.2018.13_bb0135","author":"Goldman"},{"key":"10.1038\/gim.2018.13_bb0140","author":"Klitzman"},{"key":"10.1038\/gim.2018.13_bb0145","author":"Feero"},{"key":"10.1038\/gim.2018.13_bb0150","doi-asserted-by":"crossref","unstructured":"Stacey D, L\u00e9gar\u00e9 F, Lewis K et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev 2017;Issue 4. Art. no.: CD001431 doi:doi:10.1002\/14651858.CD001431.pub5.","DOI":"10.1002\/14651858.CD001431.pub5"},{"key":"10.1038\/gim.2018.13_bb0155","author":"Ekstract"},{"key":"10.1038\/gim.2018.13_bb0160","author":"Baumgart"}],"container-title":["Genetics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/gim201813","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/gim201813.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021026022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360021026022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/gim.2018.13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/gim201813.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T01:48:29Z","timestamp":1761097709000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098360021026022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S1098360021026022"],"URL":"https:\/\/doi.org\/10.1038\/gim.2018.13","relation":{},"ISSN":["1098-3600"],"issn-type":[{"value":"1098-3600","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u201cWell, good luck with that\u201d: reactions to learning of increased genetic risk for Alzheimer disease","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/gim.2018.13","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018, The Author(s), under exclusive licence to the American College of Medical Genetics and Genomics","name":"copyright","label":"Copyright"}]}}