{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:00:16Z","timestamp":1758474016166},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T00:00:00Z","timestamp":1396483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hypertens Res"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1038\/hr.2014.57","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T06:16:00Z","timestamp":1396505760000},"page":"636-641","source":"Crossref","is-referenced-by-count":17,"title":["The effects of blood pressure and the renin\u2013angiotensin\u2013aldosterone system on regional cerebral blood flow and cognitive impairment in dialysis patients"],"prefix":"10.1038","volume":"37","author":[{"given":"Shuzo","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Mochida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiro","family":"Ishioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Machiko","family":"Oka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyouko","family":"Maesato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidekazu","family":"Moriya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumi","family":"Hidaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayasu","family":"Ohtake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,4,3]]},"reference":[{"key":"BFhr201457_CR1","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1056\/NEJMoa022066","volume":"348","author":"SE Vermer","year":"2003","unstructured":"Vermer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM . Silent brain infarcts and the risk of dementia and cognitive decline. New Engl J Med 2003; 348: 1215\u20131222.","journal-title":"New Engl J Med"},{"key":"BFhr201457_CR2","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1053\/j.ajkd.2004.03.026","volume":"44","author":"S Kobayashi","year":"2004","unstructured":"Kobayashi S, Ikeda T, Moriya H, Ohtake T, Kumagai H . Asymptomatic cerebral lacunae in patients with chronic kidney disease. Am J Kidney Dis 2004; 44: 35\u201341.","journal-title":"Am J Kidney Dis"},{"key":"BFhr201457_CR3","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1038\/hr.2011.118","volume":"34","author":"Y Yamamoto","year":"2011","unstructured":"Yamamoto Y, Ohara T, Nagakane Y, tanaka E, Morii F, Koizumi T, Akiguchi I . Chronic kidney disease, 24-h blood pressure and small vessel diseases are independently associated with cognitive impairment in lacunar infarct patients. Hepertens Res 2011; 34: 1276\u20131282.","journal-title":"Hepertens Res"},{"key":"BFhr201457_CR4","first-page":"210","volume":"2","author":"PE Teschan","year":"1975","unstructured":"Teschan PE . Electroencephalographic and other neurophysiological abnormalities in uremia. Kidney Int Suppl 1975; 2: 210\u2013216.","journal-title":"Kidney Int Suppl"},{"key":"BFhr201457_CR5","doi-asserted-by":"publisher","first-page":"248","DOI":"10.2215\/CJN.02660310","volume":"6","author":"M Kurella Tamura","year":"2011","unstructured":"Kurella Tamura M, Xie D, Yaffe K, Cohen DL, Teal V, Kasner SE, Messe SR, Sehgal AR, Kusek J, DeSalvo KB, Cornish-Zirker D, Cohan J, Seliger SL, Chertow GM, Go AS . Vascular risk factors and cognitive impairment in chronic kidney disease: The chronic renal insufficiency cohort (CRIC) study. Clin J Am Soc Nephrol 2011; 6: 248\u2013256.","journal-title":"Clin J Am Soc Nephrol"},{"key":"BFhr201457_CR6","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1681\/ASN.2008101090","volume":"20","author":"M Khatri","year":"2000","unstructured":"Khatri M, Nickolas T, Moon YP, Paik MC, Rundek T, Elkind MSV, Sacco RL, Wright CB . CKD associates with cognitive decline. J Am Soc Nephrol 2000; 20: 2427\u20132432.","journal-title":"J Am Soc Nephrol"},{"key":"BFhr201457_CR7","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1212\/WNL.0b013e3181b72629","volume":"73","author":"AS Buchman","year":"2009","unstructured":"Buchman AS, Tanne D, Boyle PA, Shah RC, Leurgans SE, Bennett DA . Kidney function is associated with the rate of cognitive decline in the elderly. Neurology 2009; 73: 920\u2013927.","journal-title":"Neurology"},{"key":"BFhr201457_CR8","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1212\/01.wnl.0000225182.15532.40","volume":"67","author":"AM Murray","year":"2006","unstructured":"Murray AM, Tupper DE, Knopman DS, Gilbertson DT, Pederson SL, Li S, Smith GE, Hochhalter AK, Collins AJ, Kane RL . Cognitive impairment in hemodialysis patients is common. Neurology 2006; 67: 216\u2013223.","journal-title":"Neurology"},{"key":"BFhr201457_CR9","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1053\/j.ajkd.2010.11.026","volume":"57","author":"P Kalirao","year":"2011","unstructured":"Kalirao P, Pederson S, Foley RN, Kolste A, Tupper D, Zaun D, Buot V, Murray AM . Cognitive impairment in peritoneal dialysis patients. Am J Kidney Dis 2011; 57: 612\u2013620.","journal-title":"Am J Kidney Dis"},{"key":"BFhr201457_CR10","first-page":"367516","volume":"2012","author":"X Jack","year":"2012","unstructured":"Jack X, de la Torre JC . Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia. Cardiovasc Psychiatry Neurol 2012; 2012: 367516.","journal-title":"Cardiovasc Psychiatry Neurol"},{"key":"BFhr201457_CR11","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/jgs.12067","volume":"61","author":"FC Goldstein","year":"2013","unstructured":"Goldstein FC, Levey AI, Steenland NK . High blood pressure and cognitive decline in mild cognitive impairment. J Am Geriatr Soc 2013; 61: 67\u201373.","journal-title":"J Am Geriatr Soc"},{"key":"BFhr201457_CR12","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1291\/hypres.18.111","volume":"18","author":"M Fujisima","year":"1995","unstructured":"Fujisima M, Ibayashi S, Fujii K, Mori S . Cerebral blood flow and brain function in hypertension. Hepertens Res 1995; 18: 111\u2013117.","journal-title":"Hepertens Res"},{"key":"BFhr201457_CR13","first-page":"1441","volume":"42","author":"S Nakano","year":"2001","unstructured":"Nakano S, Asada T, Matsuda H, Uno M, Takasaki M . Donepezil hydrochloride preserves regional cerebral blood flow in patients with Alzheimer\u2019s disease. J Nucl Med 2001; 42: 1441\u20131445.","journal-title":"J Nucl Med"},{"key":"BFhr201457_CR14","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1016\/0140-6736(90)93028-N","volume":"335","author":"DP Geaney","year":"1990","unstructured":"Geaney DP, Soper N, Shepstone BJ, Cowen PJ . Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease. Lancet 1990; 335: 1484\u20131487.","journal-title":"Lancet"},{"key":"BFhr201457_CR15","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1212\/01.WNL.0000078943.50032.FC","volume":"61","author":"D Wilkinson","year":"2003","unstructured":"Wilkinson D, Doody R, Helme R, Taubman K, Mintzer J, Kertesz A, Pratt RD . Donepezil in vascular dementia. A randomized, placebo-controlled study. Neurology 2003; 61: 479\u2013486.","journal-title":"Neurology"},{"key":"BFhr201457_CR16","first-page":"1238","volume":"36","author":"S Minoshima","year":"1995","unstructured":"Minoshima S, Frey KA, Koeppe RA, Foster NL, Kuhl DE . A diagnostic approach in Alzheimer\u2019s disease using three dimensional stereotactic surface projections of fluorine-18-FDG PET. J Nucl Med 1995; 36: 1238\u20131248.","journal-title":"J Nucl Med"},{"key":"BFhr201457_CR17","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/BF02988523","volume":"17","author":"S Mizumura","year":"2003","unstructured":"Mizumura S, Kumita S, Cho K, Ishihara M, Nakajo H, Toba M, Kumazaki T . Development of quantitative analysis method for stereotactic brain image: Assessment of reduced accumulation in extent and severity using anatomical segmentation. Ann Nucl Med 2003; 17: 289\u2013295.","journal-title":"Ann Nucl Med"},{"key":"BFhr201457_CR18","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","volume":"12","author":"MF Folstein","year":"1975","unstructured":"Folstein MF, Folstein SE, McHugh PR . \u2018Mini-mental State\u2019: a practical method for grading the cognitive state of patients for the clinician. J Psychiat Res 1975; 12: 189\u2013198.","journal-title":"J Psychiat Res"},{"key":"BFhr201457_CR19","volume-title":"Neuropsychological Assessment","author":"MD Lezak","year":"2004","unstructured":"Lezak MD, Howieson DB, Loring DW . Neuropsychological Assessment, (4th edn). Oxford University Press: Oxford. 2004."},{"key":"BFhr201457_CR20","first-page":"963","volume":"65","author":"SE O\u2019Bryant","year":"2008","unstructured":"O\u2019Bryant SE, Humphreys JD, Smith GE, Ivnik RJ, Graff-Radford NR, Petersen RC, Lucas JA . Detecting dementia with the mini-mental state examination in highly educated individuals. Arch Neurol 2008; 65: 963\u2013967.","journal-title":"Arch Neurol"},{"key":"BFhr201457_CR21","first-page":"1579","volume":"33","author":"S Minoshima","year":"1992","unstructured":"Minoshima S, Berger KL, Lee KS, Mintun MA . An automated method for rotational correction and centering of three-dimensional functional brain images. J Nuc Med 1992; 33: 1579\u20131585.","journal-title":"J Nuc Med"},{"key":"BFhr201457_CR22","volume-title":"Co-planar Stereotaxic Atlas of the Human Brain","author":"J Talairach","year":"1988","unstructured":"Talairach J, Tournoux P . Co-planar Stereotaxic Atlas of the Human Brain. Thieme Medical Publisher: New York. 1988."},{"key":"BFhr201457_CR23","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s12149-011-0534-7","volume":"26","author":"H Onishi","year":"2012","unstructured":"Onishi H, Matsutomo N, Kai Y, Kangai Y, Amijima H, Yamaguchi T . Evaluation of a novel normal database with matched SPECT systems and optimal pre-filter parameters for 3D-SSP. Ann Nucl Med 2012; 26: 16\u201325.","journal-title":"Ann Nucl Med"},{"key":"BFhr201457_CR24","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/S0140-6736(94)92871-1","volume":"344","author":"S Minoshima","year":"1994","unstructured":"Minoshima S, Foster NL, Kuhl DE . Posterior cingulate cortex in Alzheimer\u2019s disease. Lancet 1994; 344: 895.","journal-title":"Lancet"},{"key":"BFhr201457_CR25","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1212\/WNL.56.7.950","volume":"256","author":"W Jagust","year":"2001","unstructured":"Jagust W, Thisted R, Devous MD, Van Heertum R, Mayberg H, Jobst K, Smith AD, Borys N . SPECT perfusion imaging in the diagnosis of Alzheimer\u2019s disease. Neurology 2001; 256: 950\u2013956.","journal-title":"Neurology"},{"key":"BFhr201457_CR26","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1161\/01.CIR.0000138848.58269.80","volume":"110","author":"M Iwai","year":"2004","unstructured":"Iwai M, Liu HW, Chen R, Ide A, Okamoto S, Hata R, Sakanaka M, Shinuchi T, Horiuchi M . Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation. Circulation 2004; 110: 843\u2013848.","journal-title":"Circulation"},{"key":"BFhr201457_CR27","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1038\/hr.2013.51","volume":"36","author":"S Yagi","year":"2013","unstructured":"Yagi S, Akaike M, Ise T, Ueda Y, Iwase T, Sata M . Renin-angiotensin-aldosterone system has a pivotal role in cognitive impairment. Hypertens Res 2013; 36: 753\u2013758.","journal-title":"Hypertens Res"},{"key":"BFhr201457_CR28","doi-asserted-by":"publisher","first-page":"2154","DOI":"10.1161\/01.CIR.0000095676.90936.80","volume":"108","author":"MJ Sarnak","year":"2003","unstructured":"Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer P, Raij L, Spinosa DJ, Wilson PW . Kidney disease as a risk factor for development of cardiovascular disease. Circulation 2003; 108: 2154\u20132169.","journal-title":"Circulation"},{"key":"BFhr201457_CR29","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1038\/jcbfm.1987.119","volume":"7","author":"DGB Mildworf","year":"1987","unstructured":"Mildworf DGB, Rubinger D, Melamed E . The regional cerebral blood flow in patients under chronic hemodialysis treatment. J Cereb Blood Flow Metab 1987; 7: 659\u2013661.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BFhr201457_CR30","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1492-7535.2005.01141.x","volume":"9","author":"S Kobayashi","year":"2005","unstructured":"Kobayashi S, Okamoto K, Maesato K, Moriya H, Ohtake T . Important role of blood rheology in atherosclerosis of patients with hemodialysis. Hemodialy Int 2005; 9: 268\u2013274.","journal-title":"Hemodialy Int"},{"key":"BFhr201457_CR31","first-page":"F737","volume":"262","author":"H Hirakata","year":"1992","unstructured":"Hirakata H, Yao H, Osato S, Ibayashi S, Onoyama K, Otsuka M, Ichiya Y, Kuwabara Y, Masuda Y, Fujishima M. CBF . and oxygen metabolism in hemodialysis patients: effects of anemia correction with recombinant human EPO. Am J Physiol 1992; 262: F737\u2013F743.","journal-title":"Am J Physiol"},{"key":"BFhr201457_CR32","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1046\/j.1523-1755.2002.00142.x","volume":"61","author":"Y Kuwabara","year":"2002","unstructured":"Kuwabara Y, Sasaki M, Hirakata H, Koga H, Nakagawa M, Chen T, Kaneko K, Masuda K, Fujishima M . Cerebral blood flow and vasodilatory capacity in anemia secondary to chronic renal failure. Kidney Int 2002; 61: 564\u2013569.","journal-title":"Kidney Int"},{"key":"BFhr201457_CR33","doi-asserted-by":"publisher","first-page":"s129","DOI":"10.1053\/ajkd.2001.27421","volume":"38","author":"H Kanai","year":"2001","unstructured":"Kanai H, Hirakata H, Nakane H, Fujii K, Hirakata E, Ibayashi S, Kuwabara Y . Depressed cerebral oxygen metabolism in patients with chronic renal failure: a positron emission tomography study. Am J Kid Dis 2001; 38: s129\u2013s133.","journal-title":"Am J Kid Dis"},{"key":"BFhr201457_CR34","doi-asserted-by":"publisher","first-page":"c23","DOI":"10.1159\/000077592","volume":"97","author":"T Mizumasa","year":"2004","unstructured":"Mizumasa T, Hirakata H, Yoshimitsu T, Hirakata E, Kubo M, Kashiwagi M, Tanaka H, Kanai H, Fujimi S, Iida M . Dialysis-related hypotension as a cause of progressive frontal lobe atrophy in chronic hemodialysis patients: a 3-year prospevtive study. Nephron Clin Pract 2004; 97: c23\u2013c30.","journal-title":"Nephron Clin Pract"},{"key":"BFhr201457_CR35","doi-asserted-by":"publisher","first-page":"416","DOI":"10.2215\/CJN.03490807","volume":"3","author":"H Moriya","year":"2008","unstructured":"Moriya H, Oka M, Maesato K, Mano T, Ikee R, Ohtake T, Kobayashi S . Weekly averaged blood pressure is more important than a single-point blood pressure measurement in the risk stratification of dialysis patients. Clin J Am Soc Nephrol 2008; 3: 416\u2013422.","journal-title":"Clin J Am Soc Nephrol"},{"key":"BFhr201457_CR36","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s10286-006-0379-7","volume":"17","author":"S Duschek","year":"2007","unstructured":"Duschek S, Schandry R . Reduced brain perfusion and cognitive performance due to constitutional hypotension. Clin Auton Res 2007; 17: 69\u201376.","journal-title":"Clin Auton Res"}],"container-title":["Hypertension Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/hr201457.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/hr201457","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/hr201457.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T17:14:26Z","timestamp":1684430066000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/hr201457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,3]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["BFhr201457"],"URL":"https:\/\/doi.org\/10.1038\/hr.2014.57","relation":{},"ISSN":["0916-9636","1348-4214"],"issn-type":[{"value":"0916-9636","type":"print"},{"value":"1348-4214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,3]]}}}