{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:54:21Z","timestamp":1791863661838,"version":"4.3.4"},"reference-count":78,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hypertens Res"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1038\/hr.2016.126","type":"journal-article","created":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T02:16:15Z","timestamp":1475115375000},"page":"213-220","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":491,"title":["Epidemiology of hypertensive disorders in pregnancy: prevalence, risk factors, predictors and prognosis"],"prefix":"10.1038","volume":"40","author":[{"given":"Mitsumasa","family":"Umesawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gen","family":"Kobashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,9,29]]},"reference":[{"key":"BFhr2016126_CR1","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1016\/S0140-6736(06)68397-9","volume":"367","author":"KS Khan","year":"2006","unstructured":"Khan KS, Wojdyla D, Say L, G\u00fclmezoglu AM, Van Look PF . WHO analysis of causes of maternal death: a systematic review. Lancet 2006; 367: 1066\u20131074.","journal-title":"Lancet"},{"key":"BFhr2016126_CR2","doi-asserted-by":"publisher","first-page":"e323","DOI":"10.1016\/S2214-109X(14)70227-X","volume":"2","author":"L Say","year":"2014","unstructured":"Say L, Chou D, Gemmill A, Tun\u00e7alp \u00d6, Moller AB, Daniels J, G\u00fclmezoglu AM, Temmerman M, Alkema L . Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health 2014; 2: e323\u2013e333.","journal-title":"Lancet Glob Health"},{"issue":"Suppl 1","key":"BFhr2016126_CR3","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1111\/1471-0528.12633","volume":"121","author":"JP Vogel","year":"2014","unstructured":"Vogel JP, Souza JP, Mori R, Morisaki N, Lumbiganon P, Laopaiboon M, Ortiz-Panozo E, Hernandez B, P\u00e9rez-Cuevas R, Roy M, Mittal S, Cecatti JG, Tun\u00e7alp \u00d6, G\u00fclmezoglu AM WHO Multicountry Survey on Maternal and Newborn Health Research Network. Maternal complications and perinatal mortality: findings of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 2014; 121 (Suppl 1): 76\u201388.","journal-title":"BJOG"},{"key":"BFhr2016126_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2188\/jea.16.1","volume":"16","author":"G Kobashi","year":"2006","unstructured":"Kobashi G . Genetic and environmental factors associated with the development of hypertension in pregnancy. J Epidemiol 2006; 16: 1\u20138.","journal-title":"J Epidemiol"},{"key":"BFhr2016126_CR5","doi-asserted-by":"crossref","unstructured":"Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000; 183: S1\u2013S22.","DOI":"10.1067\/mob.2000.107928"},{"key":"BFhr2016126_CR6","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1111\/j.1479-828X.2000.tb01136.x","volume":"40","author":"MA Grown","year":"2000","unstructured":"Grown MA, Hague WH, Higgins J, Lowe S, McCowan L, Oats J, Peek MJ, Rowan JA, Walters BN The Australasian Society of the Study of Hypertension in Pregnancy. The detection, investigation and management of hypertension in pregnancy: full consensus statement. Aust N Z J Obstet Gynecol 2000; 40: 133\u2013155.","journal-title":"Aust N Z J Obstet Gynecol"},{"key":"BFhr2016126_CR7","doi-asserted-by":"publisher","first-page":"ix","DOI":"10.3109\/10641950109152635","volume":"20","author":"MA Brown","year":"2001","unstructured":"Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin JM . The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001; 20: ix\u2013xiv.","journal-title":"Hypertens Pregnancy"},{"key":"BFhr2016126_CR8","first-page":"1295","volume":"58","author":"M Ito","year":"2006","unstructured":"Ito M . Newly defined\/classified pregnancy-induced hypertension: comparison of pregnancy-induced hypertension with previously recognized toxemia of pregnancy. Acta Obst Gynaec Jpn 2006; 58: 1295\u20131301 (in Japanese).","journal-title":"Acta Obst Gynaec Jpn"},{"key":"BFhr2016126_CR9","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1161\/01.STR.26.6.930","volume":"26","author":"T Sharshar","year":"1995","unstructured":"Sharshar T, Lamy C, Mas JL . Incidence and causes of strokes associated with pregnancy and puerperium. A study in public hospitals of Ile de France. Stroke in Pregnancy Study Group. Stroke 1995; 26: 930\u2013936.","journal-title":"Stroke"},{"key":"BFhr2016126_CR10","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1161\/HYPERTENSIONAHA.110.150078","volume":"56","author":"ML Mongraw-Chaffin","year":"2010","unstructured":"Mongraw-Chaffin ML, Cirillo PM, Cohn BA . Preeclampsia and cardiovascular disease death: prospective evidence from the child health and development studies cohort. Hypertension 2010; 56: 166\u2013171.","journal-title":"Hypertension"},{"issue":"Suppl 1","key":"BFhr2016126_CR11","first-page":"1","volume":"118","author":"R Cantwell","year":"2011","unstructured":"Cantwell R, Clutton-Brock T, Cooper G, Dawson A, Drife J, Garrod D, Harper A, Hulbert D, Lucas S, McClure J, Millward-Sadler H, Neilson J, Nelson-Piercy C, Norman J, O\u2019Herlihy C, Oates M, Shakespeare J, de Swiet M, Williamson C, Beale V, Knight M, Lennox C, Miller A, Parmar D, Rogers J, Springett A . Saving mothers\u2019 lives: reviewing maternal deaths to make motherhood safer: 2006\u20132008. The Eighth Report of the Confidential Enquiries into Maternal Deaths in the United Kingdom. BJOG 2011; 118 (Suppl 1): 1\u2013203.","journal-title":"BJOG"},{"key":"BFhr2016126_CR12","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1111\/jog.12304","volume":"40","author":"M Morikawa","year":"2014","unstructured":"Morikawa M, Yamada T, Yamada T, Cho K, Sato S, Minakami H . Seasonal variation in the prevalence of pregnancy-induced hypertension in Japanese women. J Obstet Gynaecol Res 2014; 40: 926\u2013931.","journal-title":"J Obstet Gynaecol Res"},{"key":"BFhr2016126_CR13","doi-asserted-by":"publisher","first-page":"e100180","DOI":"10.1371\/journal.pone.0100180","volume":"9","author":"C Ye","year":"2014","unstructured":"Ye C, Ruan Y, Zou L, Li G, Li C, Chen Y, Jia C, Megson IL, Wei J, Zhang W . The 2011 survey on hypertensive disorders of pregnancy (HDP) in China: prevalence, risk factors, complications, pregnancy and perinatal outcomes. PLoS ONE 2014; 9: e100180.","journal-title":"PLoS ONE"},{"key":"BFhr2016126_CR14","first-page":"960","volume":"26","author":"R Ma","year":"2005","unstructured":"Ma R, Liu JM, Li S, Ye RW, Chen H, Xue MJ, Wang TM, Cheng LC, Zheng JC, Wu LM, Pan YJ, Chen H, Li Z . Study on the descriptive epidemiology of pregnancy-induced hypertension from 1995\u20132000 in Jiaxing of Zhejiang province, China. Zhonghua Liu Xing Bing Xue Za Zhi 2005; 26: 960\u2013963 (in Chinese).","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"BFhr2016126_CR15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/1472-6874-7-18","volume":"7","author":"V Subramaniam","year":"2007","unstructured":"Subramaniam V . Seasonal variation in the incidence of preeclampsia and eclampsia in tropical climatic conditions. BMC Womens Health 2007; 7: 18.","journal-title":"BMC Womens Health"},{"key":"BFhr2016126_CR16","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/j.1479-828X.1999.tb03372.x","volume":"39","author":"M Makhseed","year":"1999","unstructured":"Makhseed M, Musini VM, Ahmed MA, Monem RA . Influence of seasonal variation on pregnancy-induced hypertension and\/or preeclampsia. Aust N Z J Obstet Gynaecol 1999; 39: 196\u2013199.","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"BFhr2016126_CR17","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s12872-015-0110-5","volume":"15","author":"M Muti","year":"2015","unstructured":"Muti M, Tshimanga M, Notion GT, Bangure D, Chonzi P . Prevalence of pregnancy induced hypertension and pregnancy outcomes among women seeking maternity services in Harare, Zimbabwe. BMC Cardiovasc Disord 2015; 15: 111.","journal-title":"BMC Cardiovasc Disord"},{"key":"BFhr2016126_CR18","doi-asserted-by":"publisher","first-page":"215.e1","DOI":"10.1016\/j.ajog.2010.04.020","volume":"203","author":"CS Algert","year":"2010","unstructured":"Algert CS, Roberts CL, Shand AW, Morris JM, Ford JB . Seasonal variation in pregnancy hypertension is correlated with sunlight intensity. Am J Obstet Gynecol 2010; 203: 215.e1\u20135.","journal-title":"Am J Obstet Gynecol"},{"key":"BFhr2016126_CR19","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1038\/ijo.2013.117","volume":"38","author":"M Bryant","year":"2014","unstructured":"Bryant M, Santorelli G, Lawlor DA, Farrar D, Tuffnell D, Bhopal R, Wright J . A comparison of South Asian specific and established BMI thresholds for determining obesity prevalence in pregnancy and predicting pregnancy complications: findings from the Born in Bradford cohort. Int J Obes (Lond) 2014; 38: 444\u2013450.","journal-title":"Int J Obes (Lond)"},{"key":"BFhr2016126_CR20","first-page":"1116","volume":"108","author":"P Magnus","year":"2001","unstructured":"Magnus P, Eskild A . Seasonal variation in the occurrence of pre-eclampsia. BJOG 2001; 108: 1116\u20131119.","journal-title":"BJOG"},{"key":"BFhr2016126_CR21","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1093\/oxfordjournals.aje.a009400","volume":"147","author":"HS Ros","year":"1998","unstructured":"Ros HS, Cnattingius S, Lipworth L . Comparison of risk factors for preeclampsia and gestational hypertension in a population-based cohort study. Am J Epidemiol 1998; 147: 1062\u20131070.","journal-title":"Am J Epidemiol"},{"key":"BFhr2016126_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/ajh.2011.173","volume":"25","author":"K Wellington","year":"2012","unstructured":"Wellington K, Mulla ZD . Seasonal trend in the occurrence of preeclampsia and eclampsia in Texas. Am J Hypertens 2012; 25: 115\u2013119.","journal-title":"Am J Hypertens"},{"key":"BFhr2016126_CR23","doi-asserted-by":"publisher","first-page":"324.e1","DOI":"10.1016\/j.ajog.2006.11.028","volume":"196","author":"LM Bodnar","year":"2007","unstructured":"Bodnar LM, Catov JM, Roberts JM . Racial\/ethnic differences in the monthly variation of preeclampsia incidence. Am J Obstet Gynecol 2007; 196: 324.e1\u20135.","journal-title":"Am J Obstet Gynecol"},{"key":"BFhr2016126_CR24","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/j.1471-0528.2000.tb11582.x","volume":"107","author":"A Conde-Agudelo","year":"2000","unstructured":"Conde-Agudelo A, Beliz\u00e1n JM . Risk factors for pre-eclampsia in a large cohort of Latin American and Caribbean women. BJOG 2000; 107: 75\u201383.","journal-title":"BJOG"},{"key":"BFhr2016126_CR25","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/0002-9378(90)91176-D","volume":"163","author":"AF Saftlas","year":"1990","unstructured":"Saftlas AF, Olson DR, Franks AL, Atrash HK, Pokras R . Epidemiology of preeclampsia and eclampsia in the United States, 1979\u20131986. Am J Obstet Gynecol 1990; 163: 460\u2013465.","journal-title":"Am J Obstet Gynecol"},{"key":"BFhr2016126_CR26","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0020-7292(00)00240-X","volume":"70","author":"CJ Lee","year":"2000","unstructured":"Lee CJ, Hsieh TT, Chiu TH, Chen KC, Lo LM, Hung TH . Risk factors for pre-eclampsia in an Asian population. Int J Gynaecol Obstet 2000; 70: 327\u2013333.","journal-title":"Int J Gynaecol Obstet"},{"key":"BFhr2016126_CR27","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/S0020-7292(97)00241-5","volume":"60","author":"RB Cincotta","year":"1998","unstructured":"Cincotta RB, Brennecke SP . Family history of pre-eclampsia as a predictor for pre-eclampsia in primigravidas. Int J Gynaecol Obstet 1998; 60: 23\u201327.","journal-title":"Int J Gynaecol Obstet"},{"issue":"Suppl 1","key":"BFhr2016126_CR28","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1111\/1471-0528.12629","volume":"121","author":"E Abalos","year":"2014","unstructured":"Abalos E, Cuesta C, Carroli G, Qureshi Z, Widmer M, Vogel JP, Souza JP WHO Multicountry Survey on Maternal and Newborn Health Research Network. Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 2014; 121 (Suppl 1): 14\u201324.","journal-title":"BJOG"},{"key":"BFhr2016126_CR29","doi-asserted-by":"publisher","first-page":"61","DOI":"10.2188\/jea.JE20100092","volume":"21","author":"K Hayashi","year":"2011","unstructured":"Hayashi K, Matsuda Y, Kawamichi Y, Shiozaki A, Saito S . Smoking during pregnancy increases risks of various obstetric complications: a case-cohort study of the Japan Perinatal Registry Network database. J Epidemiol 2011; 21: 61\u201366.","journal-title":"J Epidemiol"},{"key":"BFhr2016126_CR30","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1038\/hr.2014.133","volume":"38","author":"M Taebi","year":"2015","unstructured":"Taebi M, Sadat Z, Saberi F, Kalahroudi MA . Early pregnancy waist-to-hip ratio and risk of preeclampsia: a prospective cohort study. Hypertens Res 2015; 38: 80\u201383.","journal-title":"Hypertens Res"},{"issue":"5 Pt 1","key":"BFhr2016126_CR31","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/0029-7844(95)00049-W","volume":"85","author":"DV Coonrod","year":"1995","unstructured":"Coonrod DV, Hickok DE, Zhu K, Easterling TR, Daling JR . Risk factors for preeclampsia in twin pregnancies: a population-based cohort study. Obstet Gynecol 1995; 85 (5 Pt 1): 645\u2013650.","journal-title":"Obstet Gynecol"},{"key":"BFhr2016126_CR32","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1111\/j.1471-0528.2009.02317.x","volume":"116","author":"SD McDonald","year":"2009","unstructured":"McDonald SD, Best C, Lam K . The recurrence risk of severe de novo pre-eclampsia in singleton pregnancies: a population-based cohort. BJOG 2009; 116: 1578\u20131584.","journal-title":"BJOG"},{"key":"BFhr2016126_CR33","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/j.1471-0528.2006.00826.x","volume":"113","author":"AS Olafsdottir","year":"2006","unstructured":"Olafsdottir AS, Skuladottir GV, Thorsdottir I, Hauksson A, Thorgeirsdottir H, Steingrimsdottir L . Relationship between high consumption of marine fatty acids in early pregnancy and hypertensive disorders in pregnancy. BJOG 2006; 113: 301\u2013309.","journal-title":"BJOG"},{"key":"BFhr2016126_CR34","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1001\/jama.1991.03470020063033","volume":"266","author":"B Eskenazi","year":"1991","unstructured":"Eskenazi B, Fenster L, Sidney S . A multivariate analysis of risk factors for preeclampsia. JAMA 1991; 266: 237\u2013241.","journal-title":"JAMA"},{"key":"BFhr2016126_CR35","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1046\/j.1365-3016.2001.00347.x","volume":"15","author":"J Zhang","year":"2001","unstructured":"Zhang J, Troendle JF, Levine RJ . Risks of hypertensive disorders in the second pregnancy. Paediatr Perinat Epidemiol 2001; 15: 226\u2013231.","journal-title":"Paediatr Perinat Epidemiol"},{"key":"BFhr2016126_CR36","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1093\/ajh\/hpv001","volume":"28","author":"NS Boghossian","year":"2015","unstructured":"Boghossian NS, Albert PS, Mendola P, Grantz KL, Yeung E . Delivery blood pressure and other first pregnancy risk factors in relation to hypertensive disorders in second pregnancies. Am J Hypertens 2015; 28: 1172\u20131179.","journal-title":"Am J Hypertens"},{"key":"BFhr2016126_CR37","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1046\/j.1464-5491.2002.00729.x","volume":"19","author":"T Cundy","year":"2002","unstructured":"Cundy T, Slee F, Gamble G, Neale L . Hypertensive disorders of pregnancy in women with Type 1 and Type 2 diabetes. Diabet Med 2002; 19: 482\u2013489.","journal-title":"Diabet Med"},{"key":"BFhr2016126_CR38","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1093\/ije\/dyl271","volume":"36","author":"JM Catov","year":"2007","unstructured":"Catov JM, Ness RB, Kip KE, Olsen J . Risk of early or severe pre-eclampsia related to pre-existing conditions. Int J Epidemiol 2007; 36: 412\u2013419.","journal-title":"Int J Epidemiol"},{"key":"BFhr2016126_CR39","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1046\/j.0004-8666.2003.00120.x","volume":"43","author":"DJ Jacobs","year":"2003","unstructured":"Jacobs DJ, Vreeburg SA, Dekker GA, Heard AR, Priest KR, Chan A . Risk factors for hypertension during pregnancy in South Australia. Aust N Z J Obstet Gynaecol 2003; 43: 421\u2013428.","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"BFhr2016126_CR40","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1111\/obr.12025","volume":"14","author":"Z Wang","year":"2013","unstructured":"Wang Z, Wang P, Liu H, He X, Zhang J, Yan H, Xu D, Wang B . Maternal adiposity as an independent risk factor for pre-eclampsia: a meta-analysis of prospective cohort studies. Obes Rev 2013; 14: 508\u2013521.","journal-title":"Obes Rev"},{"key":"BFhr2016126_CR41","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1016\/S0002-9378(99)70341-8","volume":"181","author":"A Conde-Agudelo","year":"1999","unstructured":"Conde-Agudelo A, Althabe F, Beliz\u00e1n JM, Kafury-Goeta AC . Cigarette smoking during pregnancy and risk of preeclampsia: a systematic review. Am J Obstet Gynecol 1999; 181: 1026\u20131035.","journal-title":"Am J Obstet Gynecol"},{"key":"BFhr2016126_CR42","doi-asserted-by":"crossref","first-page":"43667","DOI":"10.18632\/oncotarget.6190","volume":"6","author":"J Wei","year":"2015","unstructured":"Wei J, Liu CX, Gong TT, Wu QJ, Wu L . Cigarette smoking during pregnancy and preeclampsia risk: a systematic review and meta-analysis of prospective studies. Oncotarget 2015; 6: 43667\u201343678.","journal-title":"Oncotarget"},{"key":"BFhr2016126_CR43","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1055\/s-2002-36691","volume":"28","author":"G Kobashi","year":"2002","unstructured":"Kobashi G, Ohta K, Hata A, Shido K, Fujimoto S, Kondo K . An association between maternal smoking and preeclampsia in Japanese women. Semin Thromb Hemostat 2002; 28: 507\u2013510.","journal-title":"Semin Thromb Hemostat"},{"key":"BFhr2016126_CR44","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/ng0593-59","volume":"4","author":"K Ward","year":"1993","unstructured":"Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C, Farrington PF, Ogasawara M, Suzumori K, Tomoda S, Berrebi S, Sasaki M, Corvol P, Lifton RP, Lalouel JM . A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 1993; 4: 59\u201361.","journal-title":"Nat Genet"},{"key":"BFhr2016126_CR45","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1002\/(SICI)1096-8628(19990917)86:3<232::AID-AJMG7>3.0.CO;2-2","volume":"86","author":"G Kobashi","year":"1999","unstructured":"Kobashi G, Hata A, Shido K, Kato EH, Yamada H, Fujimoto S, Kishi R, Kondo K . Association of a variant of the angiotensinogen gene with pure type of hypertension in pregnancy in the Japanese: implication of a racial difference and significance of an age factor. Am J Med Genet 1999; 86: 232\u2013236.","journal-title":"Am J Med Genet"},{"key":"BFhr2016126_CR46","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1291\/hypres.31.1299","volume":"31","author":"MH Zafarmand","year":"2008","unstructured":"Zafarmand MH, Franx A, Sabour S, van der Schouw YT, Grobbee DE, de Leeuw PW, Bots ML . The M235T variant of the angiotensinogen gene is related to development of self-reported hypertension during pregnancy: the Prospect-EPIC cohort study. Hypertens Res 2008; 31: 1299\u20131305.","journal-title":"Hypertens Res"},{"key":"BFhr2016126_CR47","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1002\/ajmg.1535","volume":"103","author":"G Kobashi","year":"2011","unstructured":"Kobashi G, Yamada H, Kato EH, Ebina Y, Ohta K, Fujimoto S . Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy. Am J Med Genet 2011; 103: 241\u2013244.","journal-title":"Am J Med Genet"},{"key":"BFhr2016126_CR48","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1055\/s-2002-36690","volume":"28","author":"G Kobashi","year":"2002","unstructured":"Kobashi G, Hata A, Shido K, Ohta K, Yamada H, Fujimoto S, Kondo K . The M235T variant of angiotensinogen gene and body mass index are useful markers for prevention of hypertension in pregnancy; a tree-based analysis of gene-environment interaction. Semin Thromb Hemostat 2002; 28: 501\u2013505.","journal-title":"Semin Thromb Hemostat"},{"key":"BFhr2016126_CR49","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1038\/hr.2015.15","volume":"38","author":"MR Luizon","year":"2015","unstructured":"Luizon MR, Belo VA, Palei AC, Amaral LM, Lacchini R, Sandrim VC, Duarte G, Cavalli RC, Tanus-Santos JE . Effects of NAMPT polymorphisms and haplotypes on circulating visfatin\/NAMPT levels in hypertensive disorders of pregnancy. Hypertens Res 2015; 38: 361\u2013366.","journal-title":"Hypertens Res"},{"key":"BFhr2016126_CR50","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/hr.2015.29","volume":"38","author":"Y Zhan","year":"2015","unstructured":"Zhan Y, Liu M, You Y, Zhang Y, Wang J, Wang X, Liu S, Liu X . Genetic variations in the vitamin-D receptor (VDR) gene in preeclampsia patients in the Chinese Han population. Hypertens Res 2015; 38: 513\u2013517.","journal-title":"Hypertens Res"},{"key":"BFhr2016126_CR51","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.preghy.2013.04.009","volume":"3","author":"L Morgan","year":"2013","unstructured":"Morgan L . Update on genetics of pre-eclampsia. Pregnancy Hypertens 2013; 3: 59\u201360.","journal-title":"Pregnancy Hypertens"},{"key":"BFhr2016126_CR52","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1136\/bmj.38380.674340.E0","volume":"330","author":"K Duckitt","year":"2005","unstructured":"Duckitt K, Harrington D . Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ 2005; 330: 565.","journal-title":"BMJ"},{"key":"BFhr2016126_CR53","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1111\/j.1471-0528.2007.01483.x","volume":"114","author":"JS Cnossen","year":"2007","unstructured":"Cnossen JS, Leeflang MM, de Haan EE, Mol BW, van der Post JA, Khan KS, ter Riet G . Accuracy of body mass index in predicting pre-eclampsia: bivariate meta-analysis. BJOG 2007; 114: 1477\u20131485.","journal-title":"BJOG"},{"key":"BFhr2016126_CR54","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1136\/bmj.39540.522049.BE","volume":"336","author":"JS Cnossen","year":"2008","unstructured":"Cnossen JS, Vollebregt KC, de Vrieze N, ter Riet G, Mol BW, Franx A, Khan KS, van der Post JA . Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and meta-analysis. BMJ 2008; 336: 1117\u20131120.","journal-title":"BMJ"},{"key":"BFhr2016126_CR55","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1111\/1471-0528.12375","volume":"120","author":"ID Gallos","year":"2013","unstructured":"Gallos ID, Sivakumar K, Kilby MD, Coomarasamy A, Thangaratinam S, Vatish M . Pre-eclampsia is associated with, and preceded by, hypertriglyceridaemia: a meta-analysis. BJOG 2013; 120: 1321\u20131332.","journal-title":"BJOG"},{"key":"BFhr2016126_CR56","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1741-7015-7-10","volume":"7","author":"S Thangaratinam","year":"2009","unstructured":"Thangaratinam S, Coomarasamy A, O\u2019Mahony F, Sharp S, Zamora J, Khan KS, Ismail KM . Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review. BMC Med 2009; 7: 10.","journal-title":"BMC Med"},{"key":"BFhr2016126_CR57","first-page":"295","volume":"22","author":"BL Salako","year":"2003","unstructured":"Salako BL, Olayemi O, Odukogbe AT, Adedapo KS, Aimakhu CO, Alu FE, Ola B . Microalbuminuria in pregnancy as a predictor of preeclampsia and eclampsia. West Afr J Med 2003; 22: 295\u2013300.","journal-title":"West Afr J Med"},{"key":"BFhr2016126_CR58","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1111\/1471-0528.13334","volume":"122","author":"VB Brunelli","year":"2015","unstructured":"Brunelli VB, Prefumo F . Quality of first trimester risk prediction models for pre-eclampsia: a systematic review. BJOG 2015; 122: 904\u2013914.","journal-title":"BJOG"},{"key":"BFhr2016126_CR59","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1111\/1471-0528.12254","volume":"120","author":"JT Drost","year":"2013","unstructured":"Drost JT, van der Schouw YT, Maas AH, Verschuren WM . Longitudinal analysis of cardiovascular risk parameters in women with a history of hypertensive pregnancy disorders: the Doetinchem Cohort Study. BJOG 2013; 120: 1333\u20131339.","journal-title":"BJOG"},{"key":"BFhr2016126_CR60","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1161\/CIRCULATIONAHA.112.128751","volume":"127","author":"T M\u00e4nnist\u00f6","year":"2013","unstructured":"M\u00e4nnist\u00f6 T, Mendola P, V\u00e4\u00e4r\u00e4sm\u00e4ki M, J\u00e4rvelin MR, Hartikainen AL, Pouta A, Suvanto E . Elevated blood pressure in pregnancy and subsequent chronic disease risk. Circulation 2013; 127: 681\u2013690.","journal-title":"Circulation"},{"key":"BFhr2016126_CR61","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1038\/bjc.2012.195","volume":"107","author":"S Opdahl","year":"2012","unstructured":"Opdahl S, Romundstad PR, Alsaker MD, Vatten LJ . Hypertensive diseases in pregnancy and breast cancer risk. Br J Cancer 2012; 107: 176\u2013182.","journal-title":"Br J Cancer"},{"key":"BFhr2016126_CR62","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1161\/HYPERTENSIONAHA.109.130765","volume":"53","author":"JA Lykke","year":"2009","unstructured":"Lykke JA, Langhoff-Roos J, Sibai BM, Funai EF, Triche EW, Paidas MJ . Hypertensive pregnancy disorders and subsequent cardiovascular morbidity and type 2 diabetes mellitus in the mother. Hypertension 2009; 53: 944\u2013951.","journal-title":"Hypertension"},{"key":"BFhr2016126_CR63","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1503\/cmaj.120230","volume":"185","author":"IK Wang","year":"2013","unstructured":"Wang IK, Muo CH, Chang YC, Liang CC, Chang CT, Lin SY, Yen TH, Chuang FR, Chen PC, Huang CC, Wen CP, Sung FC, Morisky DE . Association between hypertensive disorders during pregnancy and end-stage renal disease: a population-based study. CMAJ 2013; 185: 207\u2013213.","journal-title":"CMAJ"},{"key":"BFhr2016126_CR64","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1001\/jama.2016.1869","volume":"315","author":"I Behrens","year":"2016","unstructured":"Behrens I, Basit S, Lykke JA, Ranthe MF, Wohlfahrt J, Bundgaard H, Melbye M, Boyd HA . Association between hypertensive disorders of pregnancy and later risk of cardiomyopathy. JAMA 2016; 315: 1026\u20131033.","journal-title":"JAMA"},{"key":"BFhr2016126_CR65","first-page":"BC05","volume":"9","author":"M Singh","year":"2015","unstructured":"Singh M, Pathak MS, Paul A . A study on atherogenic indices of pregnancy induced hypertension patients as compared to normal pregnant women. J Clin Diagn Res 2015; 9: BC05\u2013BC08.","journal-title":"J Clin Diagn Res"},{"key":"BFhr2016126_CR66","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1002\/ijc.30065","volume":"139","author":"I Behrens","year":"2016","unstructured":"Behrens I, Basit S, Jensen A, Lykke JA, Nielsen LP, Wohlfahrt J, Kjaer SK, Melbye M, Boyd HA . Hypertensive disorders of pregnancy and subsequent risk of solid cancer-a nationwide cohort study. Int J Cancer 2016; 139: 58\u201364.","journal-title":"Int J Cancer"},{"key":"BFhr2016126_CR67","doi-asserted-by":"publisher","first-page":"e009880","DOI":"10.1136\/bmjopen-2015-009880","volume":"6","author":"M Nelander","year":"2016","unstructured":"Nelander M, Cnattingius S, \u00c5kerud H, Wikstr\u00f6m J, Pedersen NL, Wikstr\u00f6m AK . Pregnancy hypertensive disease and risk of dementia and cardiovascular disease in women aged 65\u2005years or older: a cohort study. BMJ Open 2016; 6: e009880.","journal-title":"BMJ Open"},{"key":"BFhr2016126_CR68","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1016\/S0140-6736(05)67726-4","volume":"366","author":"JG Ray","year":"2005","unstructured":"Ray JG, Vermeulen MJ, Schull MJ, Redelmeier DA . Cardiovascular health after maternal placental syndromes (CHAMPS): population-based retrospective cohort study. Lancet 2005; 366: 1797\u20131803.","journal-title":"Lancet"},{"key":"BFhr2016126_CR69","doi-asserted-by":"publisher","first-page":"e7677","DOI":"10.1136\/bmj.e7677","volume":"345","author":"R Skjaerven","year":"2012","unstructured":"Skjaerven R, Wilcox AJ, Klungs\u00f8yr K, Irgens LM, Vikse BE, Vatten LJ, Lie RT . Cardiovascular mortality after pre-eclampsia in one child mothers: prospective, population based cohort study. BMJ 2012; 345: e7677.","journal-title":"BMJ"},{"key":"BFhr2016126_CR70","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1136\/heartjnl-2011-301548","volume":"98","author":"JG Ray","year":"2012","unstructured":"Ray JG, Schull MJ, Kingdom JC, Vermeulen MJ . Heart failure and dysrhythmias after maternal placental syndromes: HAD MPS Study. Heart 2012; 98: 1136\u20131141.","journal-title":"Heart"},{"key":"BFhr2016126_CR71","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1136\/bmj.326.7394.845","volume":"326","author":"BJ Wilson","year":"2003","unstructured":"Wilson BJ, Watson MS, Prescott GJ, Sunderland S, Campbell DM, Hannaford P, Smith WC . Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort study. BMJ 2003; 326: 845.","journal-title":"BMJ"},{"key":"BFhr2016126_CR72","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1016\/j.jacc.2014.02.529","volume":"63","author":"R Ahmed","year":"2014","unstructured":"Ahmed R, Dunford J, Mehran R, Robson S, Kunadian V . Pre-eclampsia and future cardiovascular risk among women: a review. J Am Coll Cardiol 2014; 63: 1815\u20131822.","journal-title":"J Am Coll Cardiol"},{"key":"BFhr2016126_CR73","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1136\/bmj.39335.385301.BE","volume":"335","author":"L Bellamy","year":"2007","unstructured":"Bellamy L, Casas JP, Hingorani AD, Williams DJ . Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 2007; 335: 974.","journal-title":"BMJ"},{"key":"BFhr2016126_CR74","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1053\/j.ajkd.2009.12.036","volume":"55","author":"SD McDonald","year":"2010","unstructured":"McDonald SD, Han Z, Walsh MW, Gerstein HC, Devereaux PJ . Kidney disease after preeclampsia: a systematic review and meta-analysis. Am J Kidney Dis 2010; 55: 1026\u20131039.","journal-title":"Am J Kidney Dis"},{"key":"BFhr2016126_CR75","unstructured":"WHO The Global Prevalence of Anaemia in 2011. World Health Organization: Geneva. 2015."},{"key":"BFhr2016126_CR76","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1093\/aje\/kwt334","volume":"179","author":"BL Pineles","year":"2014","unstructured":"Pineles BL, Park E, Samet JM . Systematic review and meta-analysis of miscarriage and maternal exposure to tobacco smoke during pregnancy. Am J Epidemiol 2014; 179: 807\u2013823.","journal-title":"Am J Epidemiol"},{"key":"BFhr2016126_CR77","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1172\/JCI119343","volume":"99","author":"I Inoue","year":"1997","unstructured":"Inoue I, Nakajima T, Williams CS, Quackenbush J, Puryear R, Powers M, Cheng T, Ludwig EH, Sharma AM, Hata A, Jeunemaitre X, Lalouel JM . A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997; 99: 1786\u20131797.","journal-title":"J Clin Invest"},{"key":"BFhr2016126_CR78","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0002-9378(99)70156-0","volume":"180","author":"T Morgan","year":"1999","unstructured":"Morgan T, Craven C, Lalouel JM, Ward K . Angiotensinogen Thr235 variant is associated with abnormal physiologic change of the uterine spiral arteries in first-trimester decidua. Am J Obstet Gynecol 1999; 180: 95\u2013102.","journal-title":"Am J Obstet Gynecol"}],"container-title":["Hypertension Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/hr2016126.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/hr2016126","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/hr2016126.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T21:10:20Z","timestamp":1640985020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/hr2016126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,29]]},"references-count":78,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["BFhr2016126"],"URL":"https:\/\/doi.org\/10.1038\/hr.2016.126","relation":{},"ISSN":["0916-9636","1348-4214"],"issn-type":[{"value":"0916-9636","type":"print"},{"value":"1348-4214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,29]]},"assertion":[{"value":"8 June 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2016","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2016","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2016","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}