{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:12:44Z","timestamp":1761487964807},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1964,12,1]],"date-time":"1964-12-01T00:00:00Z","timestamp":-160444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1964,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Haem\u2010binding proteins with properties similar to human haptoglobin and haemopexin have been demonstrated in the plasma of healthy calves electrophoresis on filter paper. Boviue haptoglobin had an electrophoretic mobility similar to that of fibrinogen, and the haemopexin migrated as a <jats:italic>\u03b2<\/jats:italic><jats:sub>1<\/jats:sub>\u2010globulin. The haemoglobin binding capacity of normal calf plasma ranged from 0\u201350 mg.\/100 ml. Subcutaneous injections of turpentine produced marked increases in the plasma concentrations of both these proteins. Plasma concentrations of haemopexin were elevated transiently in three calves infected experimentally with the nematode <jats:italic>Oesophagostomum radiatum<\/jats:italic>, but the concentration, of plasma haptoglobin rose markedly in only one of these animals.<\/jats:p><jats:p>Complexes of haemoglobin\u2010haptoglobin and haematin\u2010haemopexin were formed <jats:italic>in vivo<\/jats:italic> after the intravenous injection of lysates ol erythrocytes, and the clearance of the complexes from the plasma resulted in a depletion of the plasma concentrations of the haem\u2010binding proteins. Both haemopexin and haptoglobin disappeared from the plasma of calves during the haemolytic crisis of babesiosis. It was concluded that the simultaneous absence of both these proteins from bovine plasma was indicative of pathological haemolytic processes.<\/jats:p>","DOI":"10.1038\/icb.1964.62","type":"journal-article","created":{"date-parts":[[2007,12,15]],"date-time":"2007-12-15T10:17:30Z","timestamp":1197713850000},"page":"643-656","source":"Crossref","is-referenced-by-count":28,"title":["STUDIES ON HAPTOGLOBIN AND HAEMOPEXIN IN THE PLASMA OF CATTLE"],"prefix":"10.1111","volume":"42","author":[{"given":"KC","family":"Bremner","sequence":"first","affiliation":[{"name":"Division of Animal Health, C.S.I.R.O., Veterinary Parasitology Laboratory Yeerongpilly Queensland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1964,12]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1964.62","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb196462","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb196462.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1964.62","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb196462.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T17:20:45Z","timestamp":1695921645000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1964.62"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,12]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1964,12]]}},"alternative-id":["10.1038\/icb.1964.62"],"URL":"https:\/\/doi.org\/10.1038\/icb.1964.62","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1964,12]]}}}