{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T05:26:31Z","timestamp":1696051591032},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1966,10,1]],"date-time":"1966-10-01T00:00:00Z","timestamp":-102643200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1966,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In three controlled experiments using 32 quartets of litter\u2010mate male white mice the rates of whole\u2010body metabolism of ethyl alcohol after intraperitoneal injection of ethyl alcohol were found to be significantly slower in animals in which a fracture of the femur was produced at the time of the injection of alcohol. Pretreatment with nicotinamide at a dosage of 500 mg.\/kg. body\u2010weight caused a significant retardation of the rate of metabolism of alcohol, whereas pretreatment of fasting mice with nicotinamide at a dosage of 50 mg.\/kg. body\u2010weight significantly accelerated the rate of metabolism of alcohol. There was no significant interaction between pretreatment with either nicotinamide or diphosphopyridinenucleotide and treatment by fracturing the femur on the rate of whole\u2010body metabolism of alcohol.<\/jats:p><jats:p>It is concluded that the retardation of the rate of whole\u2010body metabolism of ethyl alcohol in mice in states of traumatic shock is not caused by diminished availability of diphosphopyridinenucleotide.<\/jats:p>","DOI":"10.1038\/icb.1966.58","type":"journal-article","created":{"date-parts":[[2007,12,15]],"date-time":"2007-12-15T09:50:45Z","timestamp":1197712245000},"page":"601-604","source":"Crossref","is-referenced-by-count":0,"title":["THE EFFECT OF TRAUMATIC SHOCK ON METABOLISM OF ETHYL ALCOHOL IN MICE"],"prefix":"10.1111","volume":"44","author":[{"given":"AWJ","family":"Lykke","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Adelaide"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ER","family":"Kosche","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Adelaide"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1966,10]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1966.58","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb196658","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb196658.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1966.58","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb196658.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T22:33:38Z","timestamp":1696026818000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1966.58"}},"subtitle":["III. THE INTERACTION OF TREATMENTS BY NICOTINAMIDE, DIPHOSPHOPYRIDINENUCLEOTIDE AND TRAUMATIC SHOCK ON THE RATE OF WHOLE\u2010BODY METABOLISM OF ETHYL ALCOHOL"],"short-title":[],"issued":{"date-parts":[[1966,10]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1966,10]]}},"alternative-id":["10.1038\/icb.1966.58"],"URL":"https:\/\/doi.org\/10.1038\/icb.1966.58","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1966,10]]}}}