{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T09:16:40Z","timestamp":1696065400335},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1973,8,1]],"date-time":"1973-08-01T00:00:00Z","timestamp":113011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1973,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Rats were transferred from water to 0\u00b775% NaCl as sole drinking fluid, Initial weight gains reversed abruptly as the rate of elimination of sodium from a standard saline load increased abruptly. Thereafter, spontaneous saline intake and the rate of sodium elimination rose in parallel to sustained maxima which were reached in six to seven weeks by saline\u2010drinking rats. Both treatment with deoxcorticosterone acetate and potassium restriction accelerated attainment of these maxima by two weeks but did not alter their magnitude. In contrast, a metabolic alkalosis induced by administration of 2 Meq. sodium citrate twice daily did not influence the rate of onset of the escape phenomenon.<\/jats:p><jats:p>It is considered that change in the rate of elimination of sodium from an acute oral saline load (0\u00b77% NaCl), equivalent to 2\u00b75% body weight, may prove a useful parameter for assessment of the degree of adaptation to saline\u2010drinking. Further, deoxcorticosterone acetate\u2010induced acceleration of adaptation to saline\u2010drinking may be a consequence of the K\u2010depletion but is unlikely to be greatly influenced by the alkalosis caused by this steroid.<\/jats:p>","DOI":"10.1038\/icb.1973.48","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T09:39:02Z","timestamp":1196156342000},"page":"521-535","source":"Crossref","is-referenced-by-count":0,"title":["SOME EFFECTS OF A RESTRICTED POTASSIUM INTAKE ON ADAPTATION TO SALINE DRINKING"],"prefix":"10.1111","volume":"51","author":[{"given":"J","family":"Marwood","sequence":"first","affiliation":[{"name":"Department of Pharmacology, The University of Western Australia Nedlands Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary F","family":"Lockett","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, The University of Western Australia Nedlands Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1973,8]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1973.48","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197348","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197348.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1973.48","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb197348.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T01:28:18Z","timestamp":1696037298000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1973.48"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,8]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1973,8]]}},"alternative-id":["10.1038\/icb.1973.48"],"URL":"https:\/\/doi.org\/10.1038\/icb.1973.48","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1973,8]]}}}