{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T00:19:57Z","timestamp":1698020397654},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1974,10,1]],"date-time":"1974-10-01T00:00:00Z","timestamp":149817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1974,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The biological properties of the homocytotropic antibody (HCA) of the marsupial <jats:italic>Setonix brachyurus<\/jats:italic> (the quokka) were closely comparable to those of eutherian (placental species) IgE. However, the quokka HCA was indistinguishable from the IgG<jats:sub>1<\/jats:sub> class. Agar gel electrophoresis, Sephadex G\u2010200 chromatography and sequential elution from DEAE\u2010cellulose and CM\u2010cellulose did not separate the passive cutaneous anaphylactic (PCA) and IgG<jats:sub>1<\/jats:sub> passive haemagglutination (HA) activities in quokka antisera. No antigenic differences between the IgG<jats:sub>1<\/jats:sub> HA antibody and the HCA were detected. In addition to quokka IgG<jats:sub>1<\/jats:sub>, tissue\u2010fixing IgG has been demonstrated in eutherian and avian species and thus it is suggested that the extant IgG and IgE classes evolved from a primitive cytotropic \u03b3 chain.<\/jats:p>","DOI":"10.1038\/icb.1974.75","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T09:42:46Z","timestamp":1196156566000},"page":"755-766","source":"Crossref","is-referenced-by-count":4,"title":["IMMEDIATE HYPERSENSITIVITY RESPONSES IN THE MARSUPIAL <i>SETONIX BRACHYURUS<\/i> (THE QUOKKA). CHARACTERIZATION OF THE HOMOCYTOTROPIC ANTIBODY"],"prefix":"10.1111","volume":"52","author":[{"given":"NR","family":"Lynch","sequence":"first","affiliation":[{"name":"Clinical Immunology Unit, The University of Western Australia, Princess Margaret Hospital Perth W.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KJ","family":"Turner","sequence":"additional","affiliation":[{"name":"Clinical Immunology Unit, The University of Western Australia, Princess Margaret Hospital Perth W.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1974,10]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1974.75","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197475","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197475.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1974.75","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb197475.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T19:27:34Z","timestamp":1696015654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1974.75"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,10]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1974,10]]}},"alternative-id":["10.1038\/icb.1974.75"],"URL":"https:\/\/doi.org\/10.1038\/icb.1974.75","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1974,10]]}}}