{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T08:42:55Z","timestamp":1696063375394},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1978,8,1]],"date-time":"1978-08-01T00:00:00Z","timestamp":270777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1978,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The effects of etilefrine on the ventral caudal artery of the rat have been examined in the presence of agents modifying sympathetic nerve function. Catecholamine levels were also measured in adjacent segments of artery to those studied pharmacologically and an attempt made to relate vascular response to etilefrine (and tyramine) with catecholamine content. Both guanethidine and reserpine produced significant attenuation of the vascular effects of etilefrine and tyramine. Pre\u2010treatment with a monoamine oxidase inhibitor caused an increase in tissue catecholamine levels but, paradoxically, depressed the vascular response to etilefrine. The significance of some of the findings in terms of an indirect component to etilefrine's action are discussed.<\/jats:p>","DOI":"10.1038\/icb.1978.56","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T10:02:01Z","timestamp":1196157721000},"page":"499-505","source":"Crossref","is-referenced-by-count":0,"title":["THE EFFECTS OF AGENTS MODIFYING SYMPATHETIC NERVE FUNCTION ON THE RESPONSE OF THE ISOLATED RAT TAIL ARTERY TO ETILEFRINE AND TYRAMINE"],"prefix":"10.1111","volume":"56","author":[{"given":"BR","family":"Frost","sequence":"first","affiliation":[{"name":"Department of Human Physiology and Pharmacology, University of Adelaide Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DB","family":"Frewin","sequence":"additional","affiliation":[{"name":"Department of Human Physiology and Pharmacology, University of Adelaide Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DC","family":"Gerke","sequence":"additional","affiliation":[{"name":"Department of Human Physiology and Pharmacology, University of Adelaide Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JA","family":"Downey","sequence":"additional","affiliation":[{"name":"Department of Human Physiology and Pharmacology, University of Adelaide Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1978,8]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1978.56","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197856","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197856.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1978.56","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb197856.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T15:51:00Z","timestamp":1696002660000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1978.56"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,8]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,8]]}},"alternative-id":["10.1038\/icb.1978.56"],"URL":"https:\/\/doi.org\/10.1038\/icb.1978.56","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1978,8]]}}}