{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:27:58Z","timestamp":1756996078655},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1978,10,1]],"date-time":"1978-10-01T00:00:00Z","timestamp":276048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1978,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In an attempt to generate large numbers of mice resistant to <jats:italic>Plasmodium berghei<\/jats:italic> and <jats:italic>Babesia rodhaini<\/jats:italic> to be used as donors of antibody\u2010secreting cells for hybridoma production, various methods of inducing resistance to repeated challenge with infected blood cells have been explored. Although, results of independent experiments varied markedly, prior injection of CBA\/H mice with BCG. and prior infection of BALB\/c mice with <jats:italic>Plasmodium yoelii,<\/jats:italic> were found to be manipulations capable of inducing resistance to <jats:italic>P. berghei<\/jats:italic>. A single dose of serum, harvested from resistant mice challenged several times with <jats:italic>P. berghei,<\/jats:italic> could transfer resistance against <jats:italic>P. berghei<\/jats:italic> to a proportion of naive CBA\/H recipients. Although resistance to multiple <jats:italic>B. rodhaini<\/jats:italic> challenge could be induced in mice, in no situation was a host protective effect of a single high dose of serum demonstrated in naive recipients.<\/jats:p>","DOI":"10.1038\/icb.1978.61","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T10:02:29Z","timestamp":1196157749000},"page":"553-559","source":"Crossref","is-referenced-by-count":8,"title":["PROTECTION OF MICE AGAINST PLASMODIUM AND BABESIA INFECTIONS: ATTEMPTS TO RAISE HOST\u2010PROTECTIVE SERA"],"prefix":"10.1111","volume":"56","author":[{"given":"GF","family":"Mitchell","sequence":"first","affiliation":[{"name":"Walter and Eliza Hall Institute, Royal Melbourne Hospital Victoria, 3050 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Handman","sequence":"additional","affiliation":[{"name":"Walter and Eliza Hall Institute, Royal Melbourne Hospital Victoria, 3050 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RJ","family":"Howard","sequence":"additional","affiliation":[{"name":"Walter and Eliza Hall Institute, Royal Melbourne Hospital Victoria, 3050 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1978,10]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1978.61","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197861","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197861.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1978.61","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb197861.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T02:14:54Z","timestamp":1696040094000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1978.61"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,10]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1978,10]]}},"alternative-id":["10.1038\/icb.1978.61"],"URL":"https:\/\/doi.org\/10.1038\/icb.1978.61","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1978,10]]}}}