{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T01:01:46Z","timestamp":1699318906984},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1979,6,1]],"date-time":"1979-06-01T00:00:00Z","timestamp":297043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1979,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Urinary calculi composed of calcium oxalate were produced in male hooded Wistar rats fed a vitamin B<jats:sub>6<\/jats:sub> deficient diet over 16 weeks. This basic diet was modified by doubling the phosphate content or loading with vitamin C or D<jats:sub>3<\/jats:sub> in three treatment groups. The number of rats developing oxalate stones was not altered by the addition of vitamin D<jats:sub>3<\/jats:sub> or phosphate, but there was a significant increase in total weight of stone formed and histological evidence of extensive renal damage in rats on the high vitamin D<jats:sub>3<\/jats:sub> diet. The addition of vitamin C to the vitamin B<jats:sub>6<\/jats:sub> deficient rats resulted in a reduction in the number of rats with uroliths and a fall in urinary oxalate excretion, while similarly loaded vitamin B<jats:sub>6<\/jats:sub> supplemented controls were free of oxalate calculi.<\/jats:p><jats:p>It is concluded that the oxalate urolithiasis induced by vitamin B<jats:sub>6<\/jats:sub> deficiency was exacerbated by added vitamin D<jats:sub>3<\/jats:sub> and reduced by vitamin C.<\/jats:p>","DOI":"10.1038\/icb.1979.27","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T10:05:05Z","timestamp":1196157905000},"page":"251-259","source":"Crossref","is-referenced-by-count":6,"title":["EXPERIMENTAL OXALATE UROLITH FORMATION IN RATS"],"prefix":"10.1111","volume":"57","author":[{"given":"GH","family":"McIntosh","sequence":"first","affiliation":[{"name":"Division of Human Nutrition, C.S.I.R.O., Kintore Avenue Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GB","family":"Belling","sequence":"additional","affiliation":[{"name":"Division of Human Nutrition, C.S.I.R.O., Kintore Avenue Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicia H","family":"Bulman","sequence":"additional","affiliation":[{"name":"Division of Human Nutrition, C.S.I.R.O., Kintore Avenue Adelaide South Australia 5000"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1979,6]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1979.27","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197927","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb197927.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1979.27","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb197927.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T12:42:08Z","timestamp":1695991328000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1979.27"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,6]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1979,6]]}},"alternative-id":["10.1038\/icb.1979.27"],"URL":"https:\/\/doi.org\/10.1038\/icb.1979.27","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1979,6]]}}}