{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T18:07:48Z","timestamp":1758823668223},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1980,6,1]],"date-time":"1980-06-01T00:00:00Z","timestamp":328665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1980,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Utilizing the techniques of radioallergosorbent test (RAST), inhibition of RAST and isoelectric focusing on polyacrylamide gels, antigenic cross\u2010reactivity has been shown between extracts of <jats:italic>Ascaris lumbricoides, Ascaris suum<\/jats:italic> and <jats:italic>Necator americanus<\/jats:italic> (hookworm). Antigenic homology is extensive between the two Ascaris preparations. The antigens common to hookworm and Ascaris, while representing a minor component of Ascaris body fluid, are nonetheless potent Stimulators of IgE antibody production in subjects infected only with hookworm larvae. These shared antigens appear to have a pI of less than 5.1. The hookworm specific antigens also have a pI of less than 5.1, whereas those specific to Ascaris have pI values in the ranges of 5.0 to 6.0 and 7.0 to 8.6. These latter antigens, i.e. those with pI between 7.0 and 8.6, apparently elicit an immune response only during an active infection with Ascaris.<\/jats:p>","DOI":"10.1038\/icb.1980.25","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T10:08:39Z","timestamp":1196158119000},"page":"249-257","source":"Crossref","is-referenced-by-count":16,"title":["HOMOLOGY BETWEEN ROUNDWORM (ASCARIS) AND HOOKWORM (<i>N. AMERICANUS<\/i>) ANTIGENS DETECTED BY HUMAN IgE ANTIBODIES"],"prefix":"10.1111","volume":"58","author":[{"given":"KJ","family":"Turner","sequence":"first","affiliation":[{"name":"Clinical Immunology Unit, Department of Microbiology, University of Western Australia, 6008"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EH","family":"Fisher","sequence":"additional","affiliation":[{"name":"Clinical Immunology Unit, Department of Microbiology, University of Western Australia, 6008"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AS","family":"McWILLIAM","sequence":"additional","affiliation":[{"name":"Clinical Immunology Unit, Department of Microbiology, University of Western Australia, 6008"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1980,6]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1980.25","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb198025","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb198025.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1980.25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb198025.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T14:52:33Z","timestamp":1695912753000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1980.25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,6]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1980,6]]}},"alternative-id":["10.1038\/icb.1980.25"],"URL":"https:\/\/doi.org\/10.1038\/icb.1980.25","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1980,6]]}}}