{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T05:26:45Z","timestamp":1696051605803},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1983,2,1]],"date-time":"1983-02-01T00:00:00Z","timestamp":412905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust J Exp Biol Med"],"published-print":{"date-parts":[[1983,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>That <jats:italic>in vitro<\/jats:italic> killing by normal and activated macrophages of <jats:italic>S. typhimurium<\/jats:italic> and other gram\u2010negative organisms is dependent on the presence of antibody has been confirmed. It has been shown that antibody is required for the binding of <jats:italic>S. typhimurium<\/jats:italic> to the surfaces of macrophages. This binding can be inhibited by the Fc portion of immunoglobulin, indicating that the Fc receptors on macrophages are used for binding <jats:italic>S. typhimuriuim<\/jats:italic>. It has also been confirmed that antibody does not appear to he necessary for killing of <jats:italic>L. monocytogenes<\/jats:italic> to occur. The organisms bind to the surface of macrophages by different receptors. Binding of <jats:italic>L. monocytogenes<\/jats:italic> occurs in the absence of added antibody and Fc fragments of immunoglobulin do not affect the binding. Attachment can be inhibited, however, by removal of divalent cations, a treatment that has no effect on antibody\u2010mediated binding as, under these conditions, the binding of <jats:italic>L. monocytogenes<\/jats:italic> to macrophages can be enhanced by antibody. The significance of these findings is discussed.<\/jats:p>","DOI":"10.1038\/icb.1983.7","type":"journal-article","created":{"date-parts":[[2007,8,13]],"date-time":"2007-08-13T13:04:13Z","timestamp":1187010253000},"page":"63-77","source":"Crossref","is-referenced-by-count":2,"title":["THE ROLE OF ANTIBODY IN THE INTERACTION OF SALMONELLA AND LISTERIA WITH PERITONEAL MACROPHAGES"],"prefix":"10.1111","volume":"61","author":[{"given":"J McA","family":"Cooper","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, University of Adelaide Adelaide South Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RB","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Adelaide Adelaide South Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Rowley","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Adelaide Adelaide South Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1983,2]]},"container-title":["Australian Journal of Experimental Biology and Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Ficb.1983.7","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb19837","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/icb19837.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/icb.1983.7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/icb19837.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T13:20:22Z","timestamp":1695993622000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/icb.1983.7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,2]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,2]]}},"alternative-id":["10.1038\/icb.1983.7"],"URL":"https:\/\/doi.org\/10.1038\/icb.1983.7","archive":["Portico"],"relation":{},"ISSN":["0818-9641"],"issn-type":[{"value":"0818-9641","type":"print"}],"subject":[],"published":{"date-parts":[[1983,2]]}}}