{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T05:26:01Z","timestamp":1696051561310},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1989,2,1]],"date-time":"1989-02-01T00:00:00Z","timestamp":602294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunol Cell Biol"],"published-print":{"date-parts":[[1989,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The addition of interleukin\u20102 (IL\u20102) to lymphocyte cultures from acute infectious mononucleosis (IM) donors dramatically increased the incidence of regression in such cultures and resulted in the emergence of an IL\u20102 dependent, CD3 Epstein\u2010Barr virus nuclear antigen (EBNA)\u2010negative cell population. Corresponding cultures seeded in the absence of IL\u20102 rarely regressed and were quickly dominated by IL\u20102 independent, CD3\u2010negative, EBNA\u2010positive cells. Lymphocyte cultures from Epstein\u2010Barr virus (EBV) seropositive donors showed enhanced regression in the presence of IL\u20102 but failed to regress after the removal of the E\u2010rosetting population. Cultures from EBV\u2010seronegative donors showed no evidence of regression in the presence or absence of IL\u20102. E\u2010rosetting cells isolated from cultures from acute IM donors that had been cultured in the presence of IL\u20102 lysed autologous and allogeneic lymphoblastoid cell lines.<\/jats:p>","DOI":"10.1038\/icb.1989.6","type":"journal-article","created":{"date-parts":[[2007,7,20]],"date-time":"2007-07-20T07:32:46Z","timestamp":1184916766000},"page":"49-55","source":"Crossref","is-referenced-by-count":0,"title":["T lymphocytes in infectious mononucleosis; Effect of IL\u20102 on the outgrowth of Epstein\u2010Barr virus\u2010infected cells"],"prefix":"10.1111","volume":"67","author":[{"given":"IS","family":"Misko","sequence":"first","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SR","family":"Burrows","sequence":"additional","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CJ","family":"Bishop","sequence":"additional","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JM","family":"Ryan","sequence":"additional","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JA","family":"Staples","sequence":"additional","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DJ","family":"Moss","sequence":"additional","affiliation":[{"name":"Queensland Institute of Medical Research Bramston Terrace Herston Brisbane Qld 4006 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1989,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91148-3"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.4049\/jimmunol.127.1.293","article-title":"Epstein\u2010Barr virus\u2010selective T cells in infectious mononucleosis are not restricted to HLA\u2010A and B antigens","volume":"172","author":"Seeley J","year":"1981","journal-title":"J. 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