{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T01:53:51Z","timestamp":1774662831358,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T00:00:00Z","timestamp":1513900800000},"content-version":"vor","delay-in-days":9944,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunology &amp; Cell Biology"],"published-print":{"date-parts":[[1990,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The ability of salivary secretions and sputum sol from patients with chronic bronchitis to inhibit the adhesion of non\u2010serotypable <jats:italic>Haemophilus influenzae<\/jats:italic> to human buccal epithelial cells has been examined. Specific <jats:italic>H. influenzae<\/jats:italic> antibodies were measured by an enzyme\u2010linked immunosorbent assay (ELISA). Saliva and sputum levels of anti\u2010 <jats:italic>H. influenzae<\/jats:italic> immunoglobulin A (IgA) antibody were related inversely to buccal cell adherence (r = \u2010 0\u00b792). Absorption of saliva and sputum sol with <jats:italic>H. influenzae<\/jats:italic> removed antibody detected by ELISA but only partially removed inhibition of attachment of bacteria. In patients with a history of recurrent bronchitis significantly more inhibitory activity remained after absorption of the secretory IgA (sIgA) specific antibody compared with patients who were resistant to acute episodes of infection (<jats:italic>P<\/jats:italic> &lt;0\u00b705). These observations suggest that factors, other than sIgA. are present in respiratory secretions and are capable of modulating <jats:italic>H. influenzae<\/jats:italic> attachment to buccal epithelial cells.<\/jats:p>","DOI":"10.1038\/icb.1990.45","type":"journal-article","created":{"date-parts":[[2007,7,6]],"date-time":"2007-07-06T11:17:13Z","timestamp":1183720633000},"page":"335-342","source":"Crossref","is-referenced-by-count":10,"title":["Inhibition of adhesion of <i>Haemophilus influenzae<\/i> to buccal cells by respiratory secretions"],"prefix":"10.1111","volume":"68","author":[{"given":"Diana C.","family":"Taylor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan W.","family":"Cripps","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Clancy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,22]]},"reference":[{"key":"e_1_2_2_2_2","first-page":"534","article-title":"The bacteriology of chronic bronchitis","author":"May J.R.","year":"1933","journal-title":"Lancet"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5677.187"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1972.tb103502.x"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)91733-5"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.29.100175.000315"},{"key":"e_1_2_2_7_2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1093\/infdis\/143.3.325","article-title":"Bacterial adherence: Adhesion\u2010receptor interactions mediating the attachment to mucosal surfaces","volume":"148","author":"Beachey E. 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