{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:32:51Z","timestamp":1761561171700},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T00:00:00Z","timestamp":1513900800000},"content-version":"vor","delay-in-days":8848,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Immunology &amp; Cell Biology"],"published-print":{"date-parts":[[1993,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Cestodes are tapeworm parasites. Infection in the intermediate host with larval (metacestode) parasites causes medically and economically important diseases known as hydatidosis and cysticercosis. Immunization against experimental infection with metacestode parasites has been highly successful, in marked contrast with the relative ineffectiveness of vaccines against infection with most parasitic organisms. High levels of immunity against a challenge infection with taeniid cestode eggs can be stimulated by immunization with extracts of the parasites, particularly with extracts of the oncosphere life\u2010cycle stage. This led to the production of a recombinant antigen vaccine against infection in sheep with the parasite <jats:italic>Taenia ovis<\/jats:italic>, the first highly effective, non\u2010living vaccine against a parasitic infection in animals or humans. This paper reviews immunity to the adult and metacestode life\u2010cycle stages of cestode parasites, development and application of the <jats:italic>T. ovis<\/jats:italic> vaccine, and prospects for vaccines against other cestode infections.<\/jats:p>","DOI":"10.1038\/icb.1993.50","type":"journal-article","created":{"date-parts":[[2007,7,3]],"date-time":"2007-07-03T09:23:10Z","timestamp":1183454590000},"page":"443-451","source":"Crossref","is-referenced-by-count":13,"title":["Vaccination against cestode parasites"],"prefix":"10.1111","volume":"71","author":[{"given":"MARSHALL W.","family":"LIGHTOWLERS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL D.","family":"RICKARD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,22]]},"reference":[{"key":"e_1_2_1_1_2","unstructured":"Eckert J. Gemmell M. A.andSoulsby E. J. L.1981.FAO\/UNEP\/WHO Guidelines for the Surveillance Prevention and Control of Echinococcosis\/Hydatidosis.World Health Organization Geneva."},{"key":"e_1_2_1_2_2","unstructured":"Gemmell M. A. Matyas Z. Pawlowski Z.andSoulsby E. J. L.1983.FAO\/UNEP\/WHO Guidelines for Surveillance Prevention and Control of Taeniasis\/Cysticercosis.World Health Organization Geneva."},{"key":"e_1_2_1_3_2","first-page":"499","article-title":"Hydatidosis: A global problem of increasing importance","volume":"55","author":"Matossian R. 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