{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:54:16Z","timestamp":1770753256868,"version":"3.50.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1038\/ijo.2013.226","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T08:35:38Z","timestamp":1386146138000},"page":"1241-1247","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Association of leptin and insulin with childhood obesity and retinal vessel diameters"],"prefix":"10.1038","volume":"38","author":[{"given":"M","family":"Siegrist","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Hanssen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Neidig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Lechner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Stetten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Blume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Lammel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Haller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Vogeser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K G","family":"Parhofer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Halle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,12,4]]},"reference":[{"key":"BFijo2013226_CR1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/j.1467-789X.2004.00133.x","volume":"5","author":"T Lobstein","year":"2004","unstructured":"Lobstein T . Summary: the rising crisis. Obes Rev 2004; 5: 4\u201385.","journal-title":"Obes Rev"},{"key":"BFijo2013226_CR2","doi-asserted-by":"publisher","first-page":"411S","DOI":"10.1093\/jn\/128.2.411S","volume":"128","author":"WH Dietz","year":"1998","unstructured":"Dietz WH . Childhood weight affects adult morbidity and mortality. J Nutr 1998; 128: 411S\u2013414S.","journal-title":"J Nutr"},{"key":"BFijo2013226_CR3","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1038\/sj.ijo.0803397","volume":"30","author":"MR Skilton","year":"2006","unstructured":"Skilton MR, Celermajer DS . Endothelial dysfunction and arterial abnormalities in childhood obesity. Int J Obes (Lond) 2006; 30: 1041\u20131049.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo2013226_CR4","doi-asserted-by":"publisher","first-page":"2371","DOI":"10.1056\/NEJMsa073166","volume":"357","author":"K Bibbins-Domingo","year":"2007","unstructured":"Bibbins-Domingo K, Coxson P, Pletcher MJ, Lightwood J, Goldman L . Adolescent overweight and future adult coronary heart disease. N Engl J Med 2007; 357: 2371\u20132379.","journal-title":"N Engl J Med"},{"key":"BFijo2013226_CR5","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1159\/000342158","volume":"229","author":"MK Ikram","year":"2012","unstructured":"Ikram MK, Ong YT, Cheung CY, Wong TY . Retinal vascular caliber measurements: clinical significance, current knowledge and future perspectives. Ophthalmologica 2012; 229: 125\u2013136.","journal-title":"Ophthalmologica"},{"key":"BFijo2013226_CR6","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1093\/eurheartj\/ehm221","volume":"28","author":"JJ Wang","year":"2007","unstructured":"Wang JJ, Liew G, Klein R, Rochtchina E, Knudtson MD, Klein BE et al. Retinal vessel diameter and cardiovascular mortality: pooled data analysis from two older populations. Eur Heart J 2007; 28: 1984\u20131992.","journal-title":"Eur Heart J"},{"key":"BFijo2013226_CR7","doi-asserted-by":"publisher","first-page":"2528","DOI":"10.1001\/jama.287.19.2528","volume":"287","author":"TY Wong","year":"2002","unstructured":"Wong TY, Klein R, Sharrett AR, Schmidt MI, Pankow JS, Couper DJ et al. Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons. JAMA 2002; 287: 2528\u20132533.","journal-title":"JAMA"},{"key":"BFijo2013226_CR8","doi-asserted-by":"publisher","first-page":"544","DOI":"10.2337\/dc07-1528","volume":"31","author":"TT Nguyen","year":"2008","unstructured":"Nguyen TT, Wang JJ, Sharrett AR, Islam FM, Klein R, Klein BE et al. Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care 2008; 31: 544\u2013549.","journal-title":"Diabetes Care"},{"key":"BFijo2013226_CR9","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/oby.2007.576","volume":"15","author":"N Cheung","year":"2007","unstructured":"Cheung N, Saw SM, Islam FM, Rogers SL, Shankar A, de HK et al. BMI and retinal vascular caliber in children. Obesity (Silver Spring) 2007; 15: 209\u2013215.","journal-title":"Obesity (Silver Spring)"},{"key":"BFijo2013226_CR10","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.3945\/ajcn.111.031641","volume":"95","author":"B Gopinath","year":"2012","unstructured":"Gopinath B, Flood VM, Wang JJ, Smith W, Rochtchina E, Louie JC et al. Carbohydrate nutrition is associated with changes in the retinal vascular structure and branching pattern in children. Am J Clin Nutr 2012; 95: 1215\u20131222.","journal-title":"Am J Clin Nutr"},{"key":"BFijo2013226_CR11","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1161\/HYPERTENSIONAHA.106.085910","volume":"49","author":"P Mitchell","year":"2007","unstructured":"Mitchell P, Cheung N, de HK, Taylor B, Rochtchina E, Islam FM et al. Blood pressure and retinal arteriolar narrowing in children. Hypertension 2007; 49: 1156\u20131162.","journal-title":"Hypertension"},{"key":"BFijo2013226_CR12","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.atherosclerosis.2011.12.029","volume":"221","author":"H Hanssen","year":"2012","unstructured":"Hanssen H, Siegrist M, Neidig M, Renner A, Birzele P, Siclovan A et al. Retinal vessel diameter, obesity and metabolic risk factors in school children (JuvenTUM 3). Atherosclerosis 2012; 221: 242\u2013248.","journal-title":"Atherosclerosis"},{"key":"BFijo2013226_CR13","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.nut.2012.07.003","volume":"29","author":"MD Deboer","year":"2013","unstructured":"Deboer MD . Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions. Nutrition 2013; 29: 379\u2013386.","journal-title":"Nutrition"},{"key":"BFijo2013226_CR14","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1161\/01.CIR.0000052939.59093.45","volume":"107","author":"TA Pearson","year":"2003","unstructured":"Pearson TA, Mensah GA, Alexander RW, Anderson JL, Cannon RO III, Criqui M et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 2003; 107: 499\u2013511.","journal-title":"Circulation"},{"key":"BFijo2013226_CR15","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/sj.ijo.0801623","volume":"25","author":"M Ciccone","year":"2001","unstructured":"Ciccone M, Vettor R, Pannacciulli N, Minenna A, Bellacicco M, Rizzon P et al. Plasma leptin is independently associated with the intima-media thickness of the common carotid artery. Int J Obes Relat Metab Disord 2001; 25: 805\u2013810.","journal-title":"Int J Obes Relat Metab Disord"},{"key":"BFijo2013226_CR16","doi-asserted-by":"publisher","first-page":"3238","DOI":"10.1161\/CIRCULATIONAHA.107.741645","volume":"117","author":"KK Koh","year":"2008","unstructured":"Koh KK, Park SM, Quon MJ . Leptin and cardiovascular disease: response to therapeutic interventions. Circulation 2008; 117: 3238\u20133249.","journal-title":"Circulation"},{"key":"BFijo2013226_CR17","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.atherosclerosis.2006.03.003","volume":"189","author":"J Beltowski","year":"2006","unstructured":"Beltowski J . Leptin and atherosclerosis. Atherosclerosis 2006; 189: 47\u201360.","journal-title":"Atherosclerosis"},{"key":"BFijo2013226_CR18","doi-asserted-by":"publisher","first-page":"17271","DOI":"10.1074\/jbc.R110.113175","volume":"285","author":"JE Hall","year":"2010","unstructured":"Hall JE, da Silva AA, do Carmo JM, Dubinion J, Hamza S, Munusamy S et al. Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem 2010; 285: 17271\u201317276.","journal-title":"J Biol Chem"},{"key":"BFijo2013226_CR19","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/j.clinbiochem.2006.07.010","volume":"39","author":"AA Venner","year":"2006","unstructured":"Venner AA, Lyon ME, Doyle-Baker PK . Leptin: a potential biomarker for childhood obesity? Clin Biochem 2006; 39: 1047\u20131056.","journal-title":"Clin Biochem"},{"key":"BFijo2013226_CR20","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1161\/01.HYP.0000242642.42177.49","volume":"48","author":"M Esler","year":"2006","unstructured":"Esler M, Straznicky N, Eikelis N, Masuo K, Lambert G, Lambert E . Mechanisms of sympathetic activation in obesity-related hypertension. Hypertension 2006; 48: 787\u2013796.","journal-title":"Hypertension"},{"key":"BFijo2013226_CR21","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1161\/01.HYP.30.6.1554","volume":"30","author":"AR Sinaiko","year":"1997","unstructured":"Sinaiko AR, Gomez-Marin O, Prineas RJ . Relation of fasting insulin to blood pressure and lipids in adolescents and parents. Hypertension 1997; 30: 1554\u20131559.","journal-title":"Hypertension"},{"key":"BFijo2013226_CR22","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1161\/01.ATV.18.7.1108","volume":"18","author":"HC McGill Jr","year":"1998","unstructured":"McGill HC Jr, McMahan CA, Tracy RE, Oalmann MC, Cornhill JF, Herderick EE et al. Relation of a postmortem renal index of hypertension to atherosclerosis and coronary artery size in young men and women. Pathobiological determinants of atherosclerosis in youth (PDAY) research group. Arterioscler Thromb Vasc Biol 1998; 18: 1108\u20131118.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"BFijo2013226_CR23","doi-asserted-by":"publisher","first-page":"e47438","DOI":"10.1371\/journal.pone.0047438","volume":"7","author":"RD Telford","year":"2012","unstructured":"Telford RD, Cunningham RB, Telford RM, Kerrigan J, Hickman PE, Potter JM et al. Effects of changes in adiposity and physical activity on preadolescent insulin resistance: the Australian LOOK longitudinal study. PloS One 2012; 7: e47438.","journal-title":"PloS One"},{"key":"BFijo2013226_CR24","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/j.clnu.2004.04.010","volume":"23","author":"M Gil-Campos","year":"2004","unstructured":"Gil-Campos M, Canete RR, Gil A . Adiponectin, the missing link in insulin resistance and obesity. Clin Nutr 2004; 23: 963\u2013974.","journal-title":"Clin Nutr"},{"key":"BFijo2013226_CR25","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/S0140-6736(03)12255-6","volume":"361","author":"J Spranger","year":"2003","unstructured":"Spranger J, Kroke A, Mohlig M, Bergmann MM, Ristow M, Boeing H et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 2003; 361: 226\u2013228.","journal-title":"Lancet"},{"key":"BFijo2013226_CR26","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.atherosclerosis.2005.12.021","volume":"189","author":"L Gilardini","year":"2006","unstructured":"Gilardini L, McTernan PG, Girola A, da Silva NF, Alberti L, Kumar S et al. Adiponectin is a candidate marker of metabolic syndrome in obese children and adolescents. Atherosclerosis 2006; 189: 401\u2013407.","journal-title":"Atherosclerosis"},{"key":"BFijo2013226_CR27","doi-asserted-by":"publisher","first-page":"468","DOI":"10.2337\/dc08-1329","volume":"32","author":"BS Metcalf","year":"2009","unstructured":"Metcalf BS, Jeffery AN, Hosking J, Voss LD, Sattar N, Wilkin TJ . Objectively measured physical activity and its association with adiponectin and other novel metabolic markers: a longitudinal study in children (EarlyBird 38). Diabetes Care 2009; 32: 468\u2013473.","journal-title":"Diabetes Care"},{"key":"BFijo2013226_CR28","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.atherosclerosis.2011.02.009","volume":"216","author":"H Hanssen","year":"2011","unstructured":"Hanssen H, Nickel T, Drexel V, Hertel G, Emslander I, Sisic Z et al. Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity. Atherosclerosis 2011; 216: 433\u2013439.","journal-title":"Atherosclerosis"},{"key":"BFijo2013226_CR29","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1161\/ATVBAHA.110.219451","volume":"31","author":"B Gopinath","year":"2011","unstructured":"Gopinath B, Baur LA, Wang JJ, Hardy LL, Teber E, Kifley A et al. Influence of physical activity and screen time on the retinal microvasculature in young children. Arterioscler Thromb Vasc Biol 2011; 31: 1233\u20131239.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"BFijo2013226_CR30","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1186\/1471-2458-11-258","volume":"11","author":"M Siegrist","year":"2011","unstructured":"Siegrist M, Hanssen H, Lammel C, Haller B, Halle M . A cluster randomised school-based lifestyle intervention programme for the prevention of childhood obesity and related early cardiovascular disease (JuvenTUM 3). BMC Public Health 2011; 11: 258.","journal-title":"BMC Public Health"},{"key":"BFijo2013226_CR31","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1007\/s001120170107","volume":"149","author":"K Kromeyer-Hauschild","year":"2001","unstructured":"Kromeyer-Hauschild K, Wabitsch M, Kunze D, Geller F, Geis HC, Hesse V et al. Perzentile f\u00fcr den Body Mass Index f\u00fcr das Kindes- und Jugendalter unter Heranziehung verschiedener deutscher Stichproben. Monatsschr Kinderheilkd 2001; 149: 807\u2013818.","journal-title":"Monatsschr Kinderheilkd"},{"key":"BFijo2013226_CR32","first-page":"45","volume":"44","author":"TJ Cole","year":"1990","unstructured":"Cole TJ . The LMS method for constructing normalized growth standards. Eur J Clin Nutr 1990; 44: 45\u201360.","journal-title":"Eur J Clin Nutr"},{"key":"BFijo2013226_CR33","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/j.2047-6310.2012.00064.x","volume":"7","author":"TJ Cole","year":"2012","unstructured":"Cole TJ, Lobstein T . Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity. Pediatr Obes 2012; 7: 284\u2013294.","journal-title":"Pediatr Obes"},{"key":"BFijo2013226_CR34","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1542\/peds.114.2.S2.555","volume":"114","author":"National High Blood Pressure Education Program Working Group on High Blood in Children and Adolescents","year":"2004","unstructured":"National High Blood Pressure Education Program Working Group on High Blood in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004; 114: 555\u2013576.","journal-title":"Pediatrics"},{"key":"BFijo2013226_CR35","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1016\/S0161-6420(99)90525-0","volume":"106","author":"LD Hubbard","year":"1999","unstructured":"Hubbard LD, Brothers RJ, King WN, Clegg LX, Klein R, Cooper LS et al. Methods for evaluation of retinal microvascular abnormalities associated with hypertension\/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 1999; 106: 2269\u20132280.","journal-title":"Ophthalmology"},{"key":"BFijo2013226_CR36","first-page":"4","volume":"14","author":"H Rusch","year":"1994","unstructured":"Rusch H, Irrgang W . M\u00fcnchner Fitnesstest. Haltung und Bewegung 1994; 14: 4\u201311.","journal-title":"Haltung und Bewegung"},{"key":"BFijo2013226_CR37","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1001\/archpedi.155.5.554","volume":"155","author":"JJ Prochaska","year":"2001","unstructured":"Prochaska JJ, Sallis JF, Long B . A physical activity screening measure for use with adolescents in primary care. Arch Pediatr Adolesc Med 2001; 155: 554\u2013559.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"BFijo2013226_CR38","unstructured":"Carroquino Salto M Percentage of Physically Active Children and Adolescents. http:\/\/www.euro.who.int\/__data\/assets\/pdf_file\/0012\/96987\/2.4.-Percentage-of-physically-active-children-EDITED_layoutedV2.pdf 2013. Fact Sheet 2.4. Accessed: 15-2-2013."},{"key":"BFijo2013226_CR39","doi-asserted-by":"publisher","first-page":"e353","DOI":"10.3109\/17477166.2010.500390","volume":"6","author":"B Gopinath","year":"2011","unstructured":"Gopinath B, Baur LA, Teber E, Liew G, Wong TY, Mitchell P . Effect of obesity on retinal vascular structure in pre-adolescent children. Int J Pediatr Obes 2011; 6: e353\u2013e359.","journal-title":"Int J Pediatr Obes"},{"key":"BFijo2013226_CR40","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1161\/01.HYP.0000082806.73530.68","volume":"42","author":"C Vecchione","year":"2003","unstructured":"Vecchione C, Aretini A, Maffei A, Marino G, Selvetella G, Poulet R et al. Cooperation between insulin and leptin in the modulation of vascular tone. Hypertension 2003; 42: 166\u2013170.","journal-title":"Hypertension"},{"key":"BFijo2013226_CR41","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1038\/oby.2006.27","volume":"14","author":"JJ Wang","year":"2006","unstructured":"Wang JJ, Taylor B, Wong TY, Chua B, Rochtchina E, Klein R et al. Retinal vessel diameters and obesity: a population-based study in older persons. Obesity (Silver Spring) 2006; 14: 206\u2013214.","journal-title":"Obesity (Silver Spring)"},{"key":"BFijo2013226_CR42","doi-asserted-by":"publisher","first-page":"2511","DOI":"10.1172\/JCI117621","volume":"94","author":"U Scherrer","year":"1994","unstructured":"Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P . Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 1994; 94: 2511\u20132515.","journal-title":"J Clin Invest"},{"key":"BFijo2013226_CR43","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.2337\/diab.46.11.1868","volume":"46","author":"L Schmetterer","year":"1997","unstructured":"Schmetterer L, Muller M, Fasching P, Diepolder C, Gallenkamp A, Zanaschka G et al. Renal and ocular hemodynamic effects of insulin. Diabetes 1997; 46: 1868\u20131874.","journal-title":"Diabetes"},{"key":"BFijo2013226_CR44","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1177\/000331979704800605","volume":"48","author":"E Bouskela","year":"1997","unstructured":"Bouskela E, Cyrino FZ, Wiernsperger N . Effects of insulin and the combination of insulin plus metformin (glucophage) on microvascular reactivity in control and diabetic hamsters. Angiology 1997; 48: 503\u2013514.","journal-title":"Angiology"},{"key":"BFijo2013226_CR45","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.mvr.2010.08.004","volume":"80","author":"LG Kraemer-Aguiar","year":"2010","unstructured":"Kraemer-Aguiar LG, Maranhao PA, Cyrino FZ, Bouskela E . Waist circumference leads to prolonged microvascular reactive hyperemia response in young overweight\/obese women. Microvasc Res 2010; 80: 427\u2013432.","journal-title":"Microvasc Res"},{"key":"BFijo2013226_CR46","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1167\/iovs.03-1390","volume":"45","author":"MK Ikram","year":"2004","unstructured":"Ikram MK, de Jong FJ, Vingerling JR, Witteman JC, Hofman A, Breteler MM et al. Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study. Invest Ophthalmol Vis Sci 2004; 45: 2129\u20132134.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BFijo2013226_CR47","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.mvr.2013.04.007","volume":"89","author":"C Bachmayer","year":"2013","unstructured":"Bachmayer C, Kemmer A, Ehrmann N, Hasenberg T, Lammert A, Hammes HP . Adipokines and endothelial dysfunction in obesity WHO degrees III. Microvasc Res 2013; 89: 129\u2013133.","journal-title":"Microvasc Res"},{"key":"BFijo2013226_CR48","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1167\/iovs.05-1539","volume":"47","author":"TY Wong","year":"2006","unstructured":"Wong TY, Islam FM, Klein R, Klein BE, Cotch MF, Castro C et al. Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA). Invest Ophthalmol Vis Sci 2006; 47: 2341\u20132350.","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/ijo2013226","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo2013226.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo2013226.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T18:23:36Z","timestamp":1647368616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ijo2013226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,4]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["BFijo2013226"],"URL":"https:\/\/doi.org\/10.1038\/ijo.2013.226","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,4]]},"assertion":[{"value":"3 April 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 November 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2013","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}