{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:32:25Z","timestamp":1787002345042,"version":"build-2736575974"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,5,14]],"date-time":"2014-05-14T00:00:00Z","timestamp":1400025600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2014,5,14]],"date-time":"2014-05-14T00:00:00Z","timestamp":1400025600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1038\/ijo.2014.79","type":"journal-article","created":{"date-parts":[[2014,5,14]],"date-time":"2014-05-14T13:15:37Z","timestamp":1400073337000},"page":"114-120","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Association between MC4R rs17782313 polymorphism and overeating behaviors"],"prefix":"10.1038","volume":"39","author":[{"given":"Z","family":"Yilmaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N J","family":"Loxton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A S","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R D","family":"Levitan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J L","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,5,14]]},"reference":[{"key":"BFijo201479_CR1","unstructured":"WHO Global Infobase. BMI\/overweight\/obesity Prevalence. World Health Organization: United States of America, 2006. Available from http:\/\/infobase.who.int."},{"key":"BFijo201479_CR2","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1038\/oby.2007.65","volume":"16","author":"BF Fuemmeler","year":"2008","unstructured":"Fuemmeler BF, Agurs-Collins TD, McClernon FJ, Kollins SH, Kail ME, Bergen AW et al. Genes implicated in serotonergic and dopaminergic functioning predict BMI categories. Obesity (Silver Spring) 2008; 16: 348\u2013355.","journal-title":"Obesity (Silver Spring)"},{"issue":"Pt 3","key":"BFijo201479_CR3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1529-8817.2005.00228.x","volume":"70","author":"AC Need","year":"2006","unstructured":"Need AC, Ahmadi KR, Spector TD, Goldstein DB . Obesity is associated with genetic variants that alter dopamine availability. Ann Hum Genet 2006; 70 (Pt 3): 293\u2013303.","journal-title":"Ann Hum Genet"},{"key":"BFijo201479_CR4","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00125-011-2346-7","volume":"55","author":"BE Grayson","year":"2012","unstructured":"Grayson BE, Seeley RJ . Deconstructing obesity: the face of fatness before and after the discovery of leptin. Diabetologia 2012; 55: 3\u20136.","journal-title":"Diabetologia"},{"key":"BFijo201479_CR5","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0092-8674(00)81865-6","volume":"88","author":"D Huszar","year":"1997","unstructured":"Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997; 88: 131\u2013141.","journal-title":"Cell"},{"key":"BFijo201479_CR6","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0065-2423(09)48004-1","volume":"48","author":"F Santini","year":"2009","unstructured":"Santini F, Maffei M, Pelosini C, Salvetti G, Scartabelli G, Pinchera A . Melanocortin-4 receptor mutations in obesity. Adv Clin Chem 2009; 48: 95\u2013109.","journal-title":"Adv Clin Chem"},{"key":"BFijo201479_CR7","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1210\/en.2010-0716","volume":"152","author":"D Srisai","year":"2011","unstructured":"Srisai D, Gillum MP, Panaro BL, Zhang XM, Kotchabhakdi N, Shulman GI et al. Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse. Endocrinology 2011; 152: 890\u2013902.","journal-title":"Endocrinology"},{"key":"BFijo201479_CR8","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1038\/ng.140","volume":"40","author":"RJ Loos","year":"2008","unstructured":"Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40: 768\u2013775.","journal-title":"Nat Genet"},{"key":"BFijo201479_CR9","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/ng.287","volume":"41","author":"CJ Willer","year":"2009","unstructured":"Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41: 25\u201334.","journal-title":"Nat Genet"},{"key":"BFijo201479_CR10","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1038\/ng.686","volume":"42","author":"EK Speliotes","year":"2010","unstructured":"Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010; 42: 937\u2013948.","journal-title":"Nat Genet"},{"key":"BFijo201479_CR11","doi-asserted-by":"publisher","first-page":"e1000916","DOI":"10.1371\/journal.pgen.1000916","volume":"6","author":"A Scherag","year":"2010","unstructured":"Scherag A, Dina C, Hinney A, Vatin V, Scherag S, Vogel CI et al. Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet 2010; 6: e1000916.","journal-title":"PLoS Genet"},{"key":"BFijo201479_CR12","doi-asserted-by":"publisher","first-page":"e18939","DOI":"10.1371\/journal.pone.0018939","volume":"6","author":"K Wang","year":"2011","unstructured":"Wang K, Li WD, Zhang CK, Wang Z, Glessner JT, Grant SF et al. A genome-wide association study on obesity and obesity-related traits. PLoS One 2011; 6: e18939.","journal-title":"PLoS One"},{"key":"BFijo201479_CR13","doi-asserted-by":"publisher","first-page":"e24303","DOI":"10.1371\/journal.pone.0024303","volume":"6","author":"L Paternoster","year":"2011","unstructured":"Paternoster L, Evans DM, Nohr EA, Holst C, Gaborieau V, Brennan P et al. Genome-wide population-based association study of extremely overweight young adults\u2014the GOYA study. PLoS One 2011; 6: e24303.","journal-title":"PLoS One"},{"key":"BFijo201479_CR14","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ymgme.2011.01.007","volume":"103","author":"S Beckers","year":"2011","unstructured":"Beckers S, Zegers D, de Freitas F, Mertens IL, Van Gaal LF, Van Hul W . Association study of MC4R with complex obesity and replication of the rs17782313 association signal. Mol Genet Metab 2011; 103: 71\u201375.","journal-title":"Mol Genet Metab"},{"key":"BFijo201479_CR15","doi-asserted-by":"publisher","first-page":"851","DOI":"10.3945\/ajcn.110.000828","volume":"93","author":"TO Kilpelainen","year":"2011","unstructured":"Kilpelainen TO, den Hoed M, Ong KK, Grontved A, Brage SEarly Growth Genetics Consortium et al. Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals. Am J Clin Nutr 2011; 93: 851\u2013860.","journal-title":"Am J Clin Nutr"},{"key":"BFijo201479_CR16","doi-asserted-by":"publisher","first-page":"2436","DOI":"10.1038\/oby.2011.237","volume":"19","author":"J Zhao","year":"2011","unstructured":"Zhao J, Bradfield JP, Zhang H, Sleiman PM, Kim CE, Glessner JT et al. Role of BMI-associated loci identified in GWAS meta-analyses in the context of common childhood obesity in European Americans. Obesity (Silver Spring) 2011; 19: 2436\u20132439.","journal-title":"Obesity (Silver Spring)"},{"key":"BFijo201479_CR17","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1001\/archgenpsychiatry.2012.191","volume":"69","author":"AK Malhotra","year":"2012","unstructured":"Malhotra AK, Correll CU, Chowdhury NI, Muller DJ, Gregersen PK, Lee AT et al. Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain. Arch Gen Psychiatry 2012; 69: 904\u2013912.","journal-title":"Arch Gen Psychiatry"},{"key":"BFijo201479_CR18","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1038\/tpj.2011.66","volume":"13","author":"NI Chowdhury","year":"2012","unstructured":"Chowdhury NI, Tiwari AK, Souza RP, Zai CC, Shaikh SA, Chen S et al. Genetic association study between antipsychotic-induced weight gain and the melanocortin-4 receptor gene. Pharmacogenomics J 2012; 13: 272\u2013279.","journal-title":"Pharmacogenomics J"},{"key":"BFijo201479_CR19","doi-asserted-by":"publisher","first-page":"R1667","DOI":"10.1152\/ajpregu.00562.2009","volume":"298","author":"D Atalayer","year":"2010","unstructured":"Atalayer D, Robertson KL, Haskell-Luevano C, Andreasen A, Rowland NE . Food demand and meal size in mice with single or combined disruption of melanocortin type 3 and 4 receptors. Am J Physiol Regul Integr Comp Physiol 2010; 298: R1667\u2013R1674.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"BFijo201479_CR20","doi-asserted-by":"publisher","first-page":"831","DOI":"10.3945\/jn.109.114439","volume":"140","author":"AL Hasselbalch","year":"2010","unstructured":"Hasselbalch AL, Angquist L, Christiansen L, Heitmann BL, Kyvik KO, Sorensen TI . A variant in the fat mass and obesity-associated gene (FTO) and variants near the melanocortin-4 receptor gene (MC4R) do not influence dietary intake. J Nutr 2010; 140: 831\u2013834.","journal-title":"J Nutr"},{"key":"BFijo201479_CR21","doi-asserted-by":"publisher","first-page":"951","DOI":"10.3945\/ajcn.2009.27781","volume":"90","author":"F Bauer","year":"2009","unstructured":"Bauer F, Elbers CC, Adan RA, Loos RJ, Onland-Moret NC, Grobbee DE et al. Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference. Am J Clin Nutr 2009; 90: 951\u2013959.","journal-title":"Am J Clin Nutr"},{"key":"BFijo201479_CR22","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1179\/147683010X12611460763643","volume":"13","author":"M Valladares","year":"2010","unstructured":"Valladares M, Dominguez-Vasquez P, Obregon AM, Weisstaub G, Burrows R, Maiz A et al. Melanocortin-4 receptor gene variants in Chilean families: association with childhood obesity and eating behavior. Nutr Neurosci 2010; 13: 71\u201378.","journal-title":"Nutr Neurosci"},{"key":"BFijo201479_CR23","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.nut.2013.05.030","volume":"30","author":"J Ho-Urriola","year":"2014","unstructured":"Ho-Urriola J, Guzman-Guzman IP, Smalley SV, Gonzalez A, Weisstaub G, Dominguez-Vasquez P et al. Melanocortin-4 receptor polymorphism rs17782313: Association with obesity and eating in the absence of hunger in Chilean children. Nutrition 2014; 30: 145\u2013149.","journal-title":"Nutrition"},{"key":"BFijo201479_CR24","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1016\/j.peptides.2004.12.028","volume":"26","author":"L Zhou","year":"2005","unstructured":"Zhou L, Williams T, Lachey JL, Kishi T, Cowley MA, Heisler LK . Serotonergic pathways converge upon central melanocortin systems to regulate energy balance. Peptides 2005; 26: 1728\u20131732.","journal-title":"Peptides"},{"key":"BFijo201479_CR25","doi-asserted-by":"publisher","first-page":"14630","DOI":"10.1523\/JNEUROSCI.5412-09.2010","volume":"30","author":"Y Xu","year":"2010","unstructured":"Xu Y, Jones JE, Lauzon DA, Anderson JG, Balthasar N, Heisler LK et al. A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. J Neurosci 2010; 30: 14630\u201314634.","journal-title":"J Neurosci"},{"key":"BFijo201479_CR26","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/nature11160","volume":"487","author":"BK Lim","year":"2012","unstructured":"Lim BK, Huang KW, Grueter BA, Rothwell PE, Malenka RC . Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens. Nature 2012; 487: 183\u2013189.","journal-title":"Nature"},{"key":"BFijo201479_CR27","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","volume":"4","author":"AT Beck","year":"1961","unstructured":"Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J . An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561\u2013571.","journal-title":"Arch Gen Psychiatry"},{"key":"BFijo201479_CR28","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1017\/S0033291700041192","volume":"11","author":"KA Halmi","year":"1981","unstructured":"Halmi KA, Falk JR, Schwartz E . Binge-eating and vomiting: a survey of a college population. Psychol Med 1981; 11: 697\u2013706.","journal-title":"Psychol Med"},{"key":"BFijo201479_CR29","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.appet.2009.05.016","volume":"53","author":"MR Lowe","year":"2009","unstructured":"Lowe MR, Butryn ML, Didie ER, Annunziato RA, Thomas JG, Crerand CE et al. The Power of Food Scale. A new measure of the psychological influence of the food environment. Appetite 2009; 53: 114\u2013118.","journal-title":"Appetite"},{"key":"BFijo201479_CR30","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1002\/1098-108X(198602)5:2<295::AID-EAT2260050209>3.0.CO;2-T","volume":"5","author":"T van Strien","year":"1986","unstructured":"van Strien T, Frijters JER, Bergers GPA, Defares PB . The Dutch Eating Behavior Questionnaire (DEBQ) for assessment of restrained, emotional, and external eating behavior. Int J Eat Disorder 1986; 5: 295\u2013315.","journal-title":"Int J Eat Disorder"},{"key":"BFijo201479_CR31","first-page":"338","volume":"103","author":"DG Schlundt","year":"2003","unstructured":"Schlundt DG, Hargreaves MK, Buchowski MS . The Eating Behavior Patterns Questionnaire predicts dietary fat intake in African American women. J Am Diet Assoc 2003; 103: 338\u2013345.","journal-title":"J Am Diet Assoc"},{"key":"BFijo201479_CR32","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0005-7894(00)80009-X","volume":"31","author":"A Cepeda-Benito","year":"2000","unstructured":"Cepeda-Benito A, Gleaves DH, Williams TL, Erath SA . The development and validation of the state and trait food-cravings questionnaires. Behav Ther 2000; 31: 151\u2013173.","journal-title":"Behav Ther"},{"key":"BFijo201479_CR33","doi-asserted-by":"publisher","first-page":"5444","DOI":"10.1093\/nar\/19.19.5444","volume":"19","author":"DK Lahiri","year":"1991","unstructured":"Lahiri DK, Nurnberger JI Jr . A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 1991; 19: 5444.","journal-title":"Nucleic Acids Res"},{"key":"BFijo201479_CR34","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1086\/383251","volume":"74","author":"DR Nyholt","year":"2004","unstructured":"Nyholt DR . A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 2004; 74: 765\u2013769.","journal-title":"Am J Hum Genet"},{"key":"BFijo201479_CR35","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","volume":"51","author":"RM Baron","year":"1986","unstructured":"Baron RM, Kenny DA . The moderator\u2013mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 1986; 51: 1173\u20131182.","journal-title":"J Pers Soc Psychol"},{"key":"BFijo201479_CR36","doi-asserted-by":"publisher","first-page":"879","DOI":"10.3758\/BRM.40.3.879","volume":"40","author":"KJ Preacher","year":"2008","unstructured":"Preacher KJ, Hayes AF . Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav Res Methods 2008; 40: 879\u2013891.","journal-title":"Behav Res Methods"},{"key":"BFijo201479_CR37","volume-title":"Multivariate Data Analysis","author":"JF Hair","year":"2009","unstructured":"Hair JF, Black B, Babin B, Anderson RE . Multivariate Data Analysis, 7th edn. Pearson Education Inc: New Jersey, 2009."},{"key":"BFijo201479_CR38","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th edn. American Psychiatric Association: Washington DC, USA, 2013.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"BFijo201479_CR39","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.4088\/JCP.11m07394","volume":"73","author":"RD Levitan","year":"2012","unstructured":"Levitan RD, Davis C, Kaplan AS, Arenovich T, Phillips DI, Ravindran AV . Obesity comorbidity in unipolar major depressive disorder: refining the core phenotype. J Clin Psychiatry 2012; 73: 1119\u20131124.","journal-title":"J Clin Psychiatry"},{"key":"BFijo201479_CR40","doi-asserted-by":"publisher","first-page":"e28912","DOI":"10.1371\/journal.pone.0028912","volume":"7","author":"G Cizza","year":"2012","unstructured":"Cizza G, Ronsaville DS, Kleitz H, Eskandari F, Mistry S, Torvik S et al. Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power study. PLoS One 2012; 7: e28912.","journal-title":"PLoS One"},{"key":"BFijo201479_CR41","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1002\/1098-108X(198809)7:5<635::AID-EAT2260070507>3.0.CO;2-K","volume":"7","author":"RM Ganley","year":"1988","unstructured":"Ganley RM . Emotional eating and how it relates to dietary restraint, disinhibition, and perceived hunger. Int J Eat Disorder 1988; 7: 635\u2013647.","journal-title":"Int J Eat Disorder"},{"key":"BFijo201479_CR42","first-page":"165","volume":"2","author":"AS Kaplan","year":"2009","unstructured":"Kaplan AS, Howlett AL, Yilmaz Z, Levitan RD . Attention deficit hyperactivity disorder and binge eating: shared phenomenology, genetics and response to treatment. Int J Child Health Adolesc Health 2009; 2: 165.","journal-title":"Int J Child Health Adolesc Health"},{"key":"BFijo201479_CR43","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s11920-010-0133-7","volume":"12","author":"C Davis","year":"2010","unstructured":"Davis C . Attention-deficit\/hyperactivity disorder: associations with overeating and obesity. Curr Psychiatry Rep 2010; 12: 389\u2013395.","journal-title":"Curr Psychiatry Rep"},{"key":"BFijo201479_CR44","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1037\/a0031209","volume":"81","author":"A Vannucci","year":"2013","unstructured":"Vannucci A, Tanofsky-Kraff M, Crosby RD, Ranzenhofer LM, Shomaker LB, Field SE et al. Latent profile analysis to determine the typology of disinhibited eating behaviors in children and adolescents. J Consult Clin Psychol 2013; 81: 494\u2013507.","journal-title":"J Consult Clin Psychol"},{"key":"BFijo201479_CR45","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1007\/s12529-013-9306-1","volume":"21","author":"G Mailloux","year":"2013","unstructured":"Mailloux G, Bergeron S, Meilleur D, D'Antono B, Dube I . Examining the associations between overeating, disinhibition, and hunger in a nonclinical sample of college women. Int J Behav Med 2013; 21: 375\u2013384.","journal-title":"Int J Behav Med"},{"key":"BFijo201479_CR46","doi-asserted-by":"publisher","first-page":"e74362","DOI":"10.1371\/journal.pone.0074362","volume":"8","author":"A Horstmann","year":"2013","unstructured":"Horstmann A, Kovacs P, Kabisch S, Boettcher Y, Schloegl H, Tonjes A et al. Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior. PLoS One 2013; 8: e74362.","journal-title":"PLoS One"},{"key":"BFijo201479_CR47","doi-asserted-by":"publisher","first-page":"7050","DOI":"10.1073\/pnas.1304707110","volume":"110","author":"BL Panaro","year":"2013","unstructured":"Panaro BL, Cone RD . Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods. Proc Natl Acad Sci USA 2013; 110: 7050\u20137055.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFijo201479_CR48","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1038\/ijo.2008.279","volume":"33","author":"F Stutzmann","year":"2009","unstructured":"Stutzmann F, Cauchi S, Durand E, Calvacanti-Proenca C, Pigeyre M, Hartikainen AL et al. Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. Int J Obes (Lond) 2009; 33: 373\u2013378.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201479_CR49","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.biopsych.2004.08.013","volume":"56","author":"RD Levitan","year":"2004","unstructured":"Levitan RD, Masellis M, Basile VS, Lam RW, Kaplan AS, Davis C et al. The dopamine-4 receptor gene associated with binge eating and weight gain in women with seasonal affective disorder: an evolutionary perspective. Biol Psychiatry 2004; 56: 665\u2013669.","journal-title":"Biol Psychiatry"},{"key":"BFijo201479_CR50","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.physbeh.2008.01.008","volume":"94","author":"NM Avena","year":"2008","unstructured":"Avena NM, Bocarsly ME, Rada P, Kim A, Hoebel BG . After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine\/acetylcholine imbalance. Physiol Behav 2008; 94: 309\u2013315.","journal-title":"Physiol Behav"},{"key":"BFijo201479_CR51","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.pnpbp.2007.09.024","volume":"32","author":"C Davis","year":"2008","unstructured":"Davis C, Levitan RD, Kaplan AS, Carter J, Reid C, Curtis C et al. Reward sensitivity and the D2 dopamine receptor gene: a case-control study of binge eating disorder. Prog Neuropsychopharmacol Biol Psychiatry 2008; 32: 620\u2013628.","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"BFijo201479_CR52","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.eatbeh.2009.01.003","volume":"10","author":"SL Hersrud","year":"2009","unstructured":"Hersrud SL, Stoltenberg SF . Epistatic interaction between COMT and DAT1 genes on eating behavior: a pilot study. Eat Behav 2009; 10: 131\u2013133.","journal-title":"Eat Behav"},{"key":"BFijo201479_CR53","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.pnpbp.2012.05.002","volume":"38","author":"C Davis","year":"2012","unstructured":"Davis C, Levitan RD, Yilmaz Z, Kaplan AS, Carter JC, Kennedy JL . Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes. Prog Neuropsychopharmacol Biol Psychiatry. 2012; 38: 328\u2013335.","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry."},{"key":"BFijo201479_CR54","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.physbeh.2010.12.017","volume":"102","author":"JF Davis","year":"2011","unstructured":"Davis JF, Choi DL, Shurdak JD, Krause EG, Fitzgerald MF, Lipton JW et al. Central melanocortins modulate mesocorticolimbic activity and food seeking behavior in the rat. Physiol Behav 2011; 102: 491\u2013495.","journal-title":"Physiol Behav"},{"key":"BFijo201479_CR55","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.physbeh.2012.01.025","volume":"106","author":"H Cui","year":"2012","unstructured":"Cui H, Mason BL, Lee C, Nishi A, Elmquist JK, Lutter M . Melanocortin 4 receptor signaling in dopamine 1 receptor neurons is required for procedural memory learning. Physiol Behav 2012; 106: 201\u2013210.","journal-title":"Physiol Behav"},{"key":"BFijo201479_CR56","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.pbb.2010.03.008","volume":"97","author":"NE Rowland","year":"2010","unstructured":"Rowland NE, Fakhar KJ, Robertson KL, Haskell-Luevano C . Effect of serotonergic anorectics on food intake and induction of Fos in brain of mice with disruption of melanocortin 3 and\/or 4 receptors. Pharmacol Biochem Behav 2010; 97: 107\u2013111.","journal-title":"Pharmacol Biochem Behav"},{"key":"BFijo201479_CR57","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.ejphar.2010.12.024","volume":"660","author":"OJ Marston","year":"2011","unstructured":"Marston OJ, Garfield AS, Heisler LK . Role of central serotonin and melanocortin systems in the control of energy balance. Eur J Pharmacol 2011; 660: 70\u201379.","journal-title":"Eur J Pharmacol"},{"key":"BFijo201479_CR58","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.1016\/j.peptides.2009.07.012","volume":"30","author":"KG Kumar","year":"2009","unstructured":"Kumar KG, Sutton GM, Dong JZ, Roubert P, Plas P, Halem HA et al. Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL\/6J mice. Peptides 2009; 30: 1892\u20131900.","journal-title":"Peptides"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/ijo201479.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo201479","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo201479.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T13:32:27Z","timestamp":1716730347000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ijo201479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,14]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["BFijo201479"],"URL":"https:\/\/doi.org\/10.1038\/ijo.2014.79","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,14]]},"assertion":[{"value":"11 January 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2014","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 April 2014","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 May 2014","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"JLK has received honoraria from Eli Lilly and Roche, whereas RDL has received honorarium from Astra-Zeneca. The remaining authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}