{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:30:51Z","timestamp":1787002251274,"version":"build-2736575974"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,5,18]],"date-time":"2015-05-18T00:00:00Z","timestamp":1431907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,5,18]],"date-time":"2015-05-18T00:00:00Z","timestamp":1431907200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1038\/ijo.2015.67","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T04:45:09Z","timestamp":1430109909000},"page":"1086-1093","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Interrelationships between obesity, obstructive sleep apnea syndrome and cardiovascular risk in obese adolescents"],"prefix":"10.1038","volume":"39","author":[{"given":"D","family":"Koren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J A","family":"Chirinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L E L","family":"Katz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E R","family":"Mohler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P R","family":"Gallagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G F","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C L","family":"Marcus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,5,18]]},"reference":[{"key":"BFijo201567_CR1","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1001\/jama.2014.732","volume":"311","author":"CL Ogden","year":"2014","unstructured":"Ogden CL, Carroll MD, Kit BK, Flegal KM . Prevalence of childhood and adult obesity in the united states, 2011-2012. JAMA 2014; 311: 806\u2013814.","journal-title":"JAMA"},{"key":"BFijo201567_CR2","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1067\/mpd.2000.105141","volume":"136","author":"A Fagot-Campagna","year":"2000","unstructured":"Fagot-Campagna A, Pettitt DJ, Engelgau MM, Burrows NR, Geiss LS, Valdez R et al. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J Pediatr 2000; 136: 664\u2013672.","journal-title":"J Pediatr"},{"key":"BFijo201567_CR3","doi-asserted-by":"publisher","first-page":"2362","DOI":"10.1056\/NEJMoa031049","volume":"350","author":"R Weiss","year":"2004","unstructured":"Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW et al. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med 2004; 350: 2362\u20132374.","journal-title":"N Engl J Med"},{"key":"BFijo201567_CR4","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1056\/NEJM199806043382302","volume":"338","author":"GS Berenson","year":"1998","unstructured":"Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, Wattigney WA . Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 1998; 338: 1650\u20131656.","journal-title":"N Engl J Med"},{"key":"BFijo201567_CR5","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1056\/NEJMsr043743","volume":"352","author":"SJ Olshansky","year":"2005","unstructured":"Olshansky SJ, Passaro DJ, Hershow RC, Layden J, Carnes BA, Brody J et al. A potential decline in life expectancy in the United States in the 21st century. N Engl J Med 2005; 352: 1138\u20131145.","journal-title":"N Engl J Med"},{"key":"BFijo201567_CR6","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1056\/NEJMoa012512","volume":"346","author":"WC Knowler","year":"2002","unstructured":"Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393\u2013403.","journal-title":"N Engl J Med"},{"issue":"1 Suppl","key":"BFijo201567_CR7","doi-asserted-by":"publisher","first-page":"222S","DOI":"10.1093\/ajcn\/82.1.222S","volume":"82","author":"RR Wing","year":"2005","unstructured":"Wing RR, Phelan S . Long-term weight loss maintenance. Am J Clin Nutr 2005; 82 (1 Suppl): 222S\u2013225SS.","journal-title":"Am J Clin Nutr"},{"key":"BFijo201567_CR8","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1001\/jama.291.16.2013","volume":"291","author":"T Young","year":"2004","unstructured":"Young T, Skatrud J, Peppard PE . Risk factors for obstructive sleep apnea in adults. JAMA 2004; 291: 2013\u20132016.","journal-title":"JAMA"},{"key":"BFijo201567_CR9","doi-asserted-by":"crossref","unstructured":"Standards and indications for cardiopulmonary sleep studies in children. American Thoracic Society. Am J Respir Crit Care Med 1996; 153: 866\u2013878.","DOI":"10.1164\/ajrccm.153.2.8564147"},{"key":"BFijo201567_CR10","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1111\/j.1524-6175.2006.888139.x","volume":"8","author":"LM Prisant","year":"2006","unstructured":"Prisant LM, Dillard TA, Blanchard AR . Obstructive sleep apnea syndrome. J Clin Hypertens (Greenwich) 2006; 8: 746\u2013750.","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"BFijo201567_CR11","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1378\/chest.07-0828","volume":"133","author":"E Tasali","year":"2008","unstructured":"Tasali E, Mokhlesi B, Van Cauter E . Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest 2008; 133: 496\u2013506.","journal-title":"Chest"},{"key":"BFijo201567_CR12","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1164\/rccm.200412-1652OC","volume":"172","author":"K Minoguchi","year":"2005","unstructured":"Minoguchi K, Yokoe T, Tazaki T, Minoguchi H, Tanaka A, Oda N et al. Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea. Am J Respir Crit Care Med 2005; 172: 625\u2013630.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR13","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1590\/S1807-59322005000200014","volume":"60","author":"LF Drager","year":"2005","unstructured":"Drager LF, Silva HB, Bortolotto LA . Increased arterial distensibility and renovascular hypertension in Goldenhar syndrome. Clinics (Sao Paulo) 2005; 60: 173\u2013176.","journal-title":"Clinics (Sao Paulo)"},{"key":"BFijo201567_CR14","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1164\/ajrccm.163.1.2001008","volume":"163","author":"E Shahar","year":"2001","unstructured":"Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Javier Nieto F et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 2001; 163: 19\u201325.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR15","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1164\/rccm.200703-375OC","volume":"176","author":"S Redline","year":"2007","unstructured":"Redline S, Storfer-Isser A, Rosen CL, Johnson NL, Kirchner HL, Emancipator J et al. Association between metabolic syndrome and sleep- disordered breathing in adolescents. Am J Respir Crit Care Med 2007; 176: 401\u2013408.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR16","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1093\/sleep\/28.6.747","volume":"28","author":"LM O'Brien","year":"2005","unstructured":"O'Brien LM, Gozal D . Autonomic dysfunction in children with sleep- disordered breathing. Sleep 2005; 28: 747\u2013752.","journal-title":"Sleep"},{"key":"BFijo201567_CR17","doi-asserted-by":"publisher","first-page":"2307","DOI":"10.1161\/CIRCULATIONAHA.107.696823","volume":"116","author":"D Gozal","year":"2007","unstructured":"Gozal D, Kheirandish-Gozal L, Serpero LD, Sans Capdevila O, Dayyat E . Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. Circulation 2007; 116: 2307\u20132314.","journal-title":"Circulation"},{"key":"BFijo201567_CR18","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1542\/peds.109.1.45","volume":"109","author":"CL Ogden","year":"2002","unstructured":"Ogden CL, Kuczmarski RJ, Flegal KM, Mei Z, Guo S, Wei R et al. Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version. Pediatrics 2002; 109: 45\u201360.","journal-title":"Pediatrics"},{"key":"BFijo201567_CR19","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1002\/ppul.20002","volume":"37","author":"AG Kaditis","year":"2004","unstructured":"Kaditis AG, Finder J, Alexopoulos EI, Starantzis K, Tanou K, Gampeta S et al. Sleep-disordered breathing in 3,680 Greek children. Pediatr Pulmonol 2004; 37: 499\u2013509.","journal-title":"Pediatr Pulmonol"},{"key":"BFijo201567_CR20","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","author":"WT Friedewald","year":"1972","unstructured":"Friedewald WT, Levy RI, Fredrickson DS . Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499\u2013502.","journal-title":"Clin Chem"},{"key":"BFijo201567_CR21","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1007\/BF00280883","volume":"28","author":"DR Matthews","year":"1985","unstructured":"Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC . Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412\u2013419.","journal-title":"Diabetologia"},{"key":"BFijo201567_CR22","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1111\/j.1365-2796.1994.tb00847.x","volume":"236","author":"DE Grobbee","year":"1994","unstructured":"Grobbee DE, Bots ML . Carotid artery intima-media thickness as an indicator of generalized atherosclerosis. J Intern Med 1994; 236: 567\u2013573.","journal-title":"J Intern Med"},{"key":"BFijo201567_CR23","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1111\/j.1475-097X.1991.tb00676.x","volume":"11","author":"I Wendelhag","year":"1991","unstructured":"Wendelhag I, Gustavsson T, Suurkula M, Berglund G, Wikstrand J . Ultrasound measurement of wall thickness in the carotid artery: fundamental principles and description of a computerized analysing system. Clin Physiol 1991; 11: 565\u2013577.","journal-title":"Clin Physiol"},{"key":"BFijo201567_CR24","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/sj.jhh.1001628","volume":"18","author":"S Takiuchi","year":"2004","unstructured":"Takiuchi S, Kamide K, Miwa Y, Tomiyama M, Yoshii M, Matayoshi T et al. Diagnostic value of carotid intima-media thickness and plaque score for predicting target organ damage in patients with essential hypertension. J Hum Hypertens 2004; 18: 17\u201323.","journal-title":"J Hum Hypertens"},{"key":"BFijo201567_CR25","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1161\/01.CIR.0000033824.02722.F7","volume":"106","author":"K Cruickshank","year":"2002","unstructured":"Cruickshank K, Riste L, Anderson SG, Wright JS, Dunn G, Gosling RG . Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 2002; 106: 2085\u20132090.","journal-title":"Circulation"},{"key":"BFijo201567_CR26","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.jacc.2013.09.063","volume":"63","author":"Y Ben-Shlomo","year":"2014","unstructured":"Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ et al. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol 2014; 63: 636\u2013646.","journal-title":"J Am Coll Cardiol"},{"key":"BFijo201567_CR27","doi-asserted-by":"publisher","first-page":"2955","DOI":"10.1161\/01.CIR.0000020500.77568.3C","volume":"105","author":"GF Mitchell","year":"2002","unstructured":"Mitchell GF, Izzo JL Jr ., Lacourciere Y, Ouellet JP, Neutel J, Qian C et al. Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: results of the conduit hemodynamics of omapatrilat international research study. Circulation 2002; 105: 2955\u20132961.","journal-title":"Circulation"},{"key":"BFijo201567_CR28","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events : Rules, Terminology and Technical Specifications","author":"C Iber","year":"2007","unstructured":"Iber C, American Academy of Sleep Medicine The AASM Manual for the Scoring of Sleep and Associated Events : Rules, Terminology and Technical Specifications. American Academy of Sleep Medicine: Westchester, IL: Westchester, IL, 2007. 59 str. p."},{"key":"BFijo201567_CR29","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1164\/ajrccm.168.12.954","volume":"168","author":"MB Witmans","year":"2003","unstructured":"Witmans MB, Keens TG, Davidson Ward SL, Marcus CL . Obstructive hypopneas in children and adolescents: normal values. Am J Respir Crit Care Med 2003; 168: 1540.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR30","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1002\/ppul.20236","volume":"40","author":"N Traeger","year":"2005","unstructured":"Traeger N, Schultz B, Pollock AN, Mason T, Marcus CL, Arens R . Polysomnographic values in children 2-9 years old: additional data and review of the literature. Pediatr Pulmonol 2005; 40: 22\u201330.","journal-title":"Pediatr Pulmonol"},{"key":"BFijo201567_CR31","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1007\/s00415-006-0110-6","volume":"253","author":"M Saletu","year":"2006","unstructured":"Saletu M, Nosiska D, Kapfhammer G, Lalouschek W, Saletu B, Benesch T et al. Structural and serum surrogate markers of cerebrovascular disease in obstructive sleep apnea (OSA): association of mild OSA with early atherosclerosis. J Neurol 2006; 253: 746\u2013752.","journal-title":"J Neurol"},{"key":"BFijo201567_CR32","first-page":"850","volume":"25","author":"S Jelic","year":"2002","unstructured":"Jelic S, Bartels MN, Mateika JH, Ngai P, DeMeersman RE, Basner RC . Arterial stiffness increases during obstructive sleep apneas. Sleep 2002; 25: 850\u2013855.","journal-title":"Sleep"},{"key":"BFijo201567_CR33","doi-asserted-by":"publisher","first-page":"1544","DOI":"10.1164\/rccm.201311-2012OC","volume":"189","author":"F Campos-Rodriguez","year":"2014","unstructured":"Campos-Rodriguez F, Martinez-Garcia MA, Reyes-Nu\u00f1ez N, Caballero- Martinez I, Catalan-Serra P, Almeida-Gonzalez CV . Role of Sleep Apnea and CPAP therapy in the incidence of stroke or coronary heart disease in women. Am J Respir Crit Care Med 2014; 189: 1544\u20131550.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR34","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.rmed.2005.04.009","volume":"100","author":"GC Hagenah","year":"2006","unstructured":"Hagenah GC, Gueven E, Andreas S . Influence of obstructive sleep apnoea in coronary artery disease: A 10-year follow-up. Respir Med 2006; 100: 180\u2013182.","journal-title":"Respir Med"},{"key":"BFijo201567_CR35","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1136\/thoraxjnl-2012-202178","volume":"67","author":"SE Craig","year":"2012","unstructured":"Craig SE, Kohler M, Nicoll D, Bratton DJ, Nunn A, Davies R et al. Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial. Thorax 2012; 67: 1090\u20131096.","journal-title":"Thorax"},{"key":"BFijo201567_CR36","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.jpeds.2005.06.008","volume":"147","author":"S Stabouli","year":"2005","unstructured":"Stabouli S, Kotsis V, Papamichael C, Constantopoulos A, Zakopoulos N . Adolescent obesity is associated with high ambulatory blood pressure and increased carotid intimal-medial thickness. J Pediatr 2005; 147: 651\u2013656.","journal-title":"J Pediatr"},{"key":"BFijo201567_CR37","doi-asserted-by":"publisher","first-page":"2273","DOI":"10.1016\/j.jacc.2009.03.026","volume":"53","author":"JD Dawson","year":"2009","unstructured":"Dawson JD, Sonka M, Blecha MB, Lin W, Davis PH . Risk factors associated with aortic and carotid intima-media thickness in adolescents and young adults: the Muscatine Offspring Study. J Am Coll Cardiol 2009; 53: 2273\u20132279.","journal-title":"J Am Coll Cardiol"},{"key":"BFijo201567_CR38","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3109\/17477160903473705","volume":"5","author":"B Dubern","year":"2010","unstructured":"Dubern B, Aggoun Y, Boule M, Fauroux B, Bonnet D, Tounian P . Arterial alterations in severely obese children with obstructive sleep apnoea. Int J Pediatr Obes 2010; 5: 230\u2013236.","journal-title":"Int J Pediatr Obes"},{"issue":"23 Suppl 1","key":"BFijo201567_CR39","first-page":"III27","volume":"109","author":"J Davignon","year":"2004","unstructured":"Davignon J, Ganz P . Role of endothelial dysfunction in atherosclerosis. Circulation 2004; 109 (23 Suppl 1): III27\u2013III32.","journal-title":"Circulation"},{"key":"BFijo201567_CR40","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.atherosclerosis.2011.08.007","volume":"220","author":"T Koivistoinen","year":"2012","unstructured":"Koivistoinen T, Virtanen M, Hutri-Kahonen N, Lehtimaki T, Jula A, Juonala M et al. Arterial pulse wave velocity in relation to carotid intima- media thickness, brachial flow-mediated dilation and carotid artery distensibility: the Cardiovascular Risk in Young Finns Study and the Health 2000 Survey. Atherosclerosis 2012; 220: 387\u2013393.","journal-title":"Atherosclerosis"},{"key":"BFijo201567_CR41","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1161\/01.CIR.0000061757.12581.15","volume":"107","author":"TD Bradley","year":"2003","unstructured":"Bradley TD, Floras JS . Sleep apnea and heart failure: Part I: obstructive sleep apnea. Circulation 2003; 107: 1671\u20131678.","journal-title":"Circulation"},{"key":"BFijo201567_CR42","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s00125-011-2412-1","volume":"55","author":"EM Urbina","year":"2012","unstructured":"Urbina EM, Gao Z, Khoury PR, Martin LJ, Dolan LM . Insulin resistance and arterial stiffness in healthy adolescents and young adults. Diabetologia 2012; 55: 625\u2013631.","journal-title":"Diabetologia"},{"key":"BFijo201567_CR43","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1172\/JCI103241","volume":"34","author":"JL Patterson Jr","year":"1955","unstructured":"Patterson JL Jr ., Heyman A, Battey LL, Ferguson RW . Threshold of response of the cerebral vessels of man to increase in blood carbon dioxide. J Clin Invest 1955; 34: 1857\u20131864.","journal-title":"J Clin Invest"},{"key":"BFijo201567_CR44","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1172\/JCI105561","volume":"46","author":"RD Gordon","year":"1967","unstructured":"Gordon RD, Kuchel O, Liddle GW, Island DP . Role of the sympathetic nervous system in regulating renin and aldosterone production in man. J Clin Invest 1967; 46: 599\u2013605.","journal-title":"J Clin Invest"},{"key":"BFijo201567_CR45","doi-asserted-by":"publisher","first-page":"e000091","DOI":"10.1161\/JAHA.111.000091","volume":"1","author":"DJ Durgan","year":"2012","unstructured":"Durgan DJ, Bryan RM . Cerebrovascular consequences of obstructive sleep apnea. J Am Heart Assoc 2012; 1: e000091.","journal-title":"J Am Heart Assoc"},{"issue":"Pt 11","key":"BFijo201567_CR46","doi-asserted-by":"publisher","first-page":"3398","DOI":"10.1093\/brain\/awr253","volume":"134","author":"GF Mitchell","year":"2011","unstructured":"Mitchell GF, van Buchem MA, Sigurdsson S, Gotal JD, Jonsdottir MK, Kjartansson O et al. Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene\/Environment Susceptibility\u2013Reykjavik study. Brain 2011; 134 (Pt 11): 3398\u20133407.","journal-title":"Brain"},{"key":"BFijo201567_CR47","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1164\/rccm.200503-340OC","volume":"172","author":"LF Drager","year":"2005","unstructured":"Drager LF, Bortolotto LA, Lorenzi MC, Figueiredo AC, Krieger EM, Lorenzi-Filho G . Early signs of atherosclerosis in obstructive sleep apnea. Am J Respir Crit Care Med 2005; 172: 613\u2013618.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR48","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1164\/rccm.200610-1519OC","volume":"176","author":"D Gozal","year":"2007","unstructured":"Gozal D, Crabtree VM, Sans Capdevila O, Witcher LA, Kheirandish-Gozal L . C-reactive protein, obstructive sleep apnea, and cognitive dysfunction in school-aged children. Am J Respir Crit Care Med 2007; 176: 188\u2013193.","journal-title":"Am J Respir Crit Care Med"},{"key":"BFijo201567_CR49","doi-asserted-by":"publisher","first-page":"405","DOI":"10.3109\/17477160902957133","volume":"4","author":"JG Woo","year":"2009","unstructured":"Woo JG . Using body mass index Z-score among severely obese adolescents: a cautionary note. Int J Pediatr Obes 2009; 4: 405\u2013410.","journal-title":"Int J Pediatr Obes"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/ijo201567.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo201567","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo201567.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T15:23:39Z","timestamp":1647357819000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ijo201567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,18]]},"references-count":49,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["BFijo201567"],"URL":"https:\/\/doi.org\/10.1038\/ijo.2015.67","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,18]]},"assertion":[{"value":"24 April 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2014","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2014","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2015","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"LE Levitt Katz provides consultation services to Janssen pharmaceuticals and to Takeda Pharmaceuticals. CL Marcus has research support from Ventus and Philips Respironics in the form of loaned equipment only for investigator-initiated studies, not relevant to the current manuscript. Dr Mitchell is the owner of Cardiovascular Engineering, Inc., a company that develops and manufactures devices to measure vascular stiffness, serves as a consultant to and receives honoraria from Novartis, Merck and Enopace, and is funded by research grants HL094898, DK082447, HL107385 and HL104184 from the National Institutes of Health. The remaining authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}