{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T21:27:03Z","timestamp":1783718823018,"version":"3.55.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T00:00:00Z","timestamp":1454976000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T00:00:00Z","timestamp":1454976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1038\/ijo.2016.22","type":"journal-article","created":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T08:56:13Z","timestamp":1455008173000},"page":"1119-1125","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":97,"title":["Influence of physical fitness on cardio-metabolic risk factors in European children. The IDEFICS study"],"prefix":"10.1038","volume":"40","author":[{"given":"M","family":"Zaqout","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Michels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Bammann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Ahrens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Sprengeler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Molnar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Hadjigeorgiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Eiben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Konstabel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Jim\u00e9nez-Pav\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L A","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"De Henauw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the IDEFICS consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,2,9]]},"reference":[{"key":"BFijo201622_CR1","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1016\/S0140-6736(12)61728-0","volume":"380","author":"R Lozano","year":"2012","unstructured":"Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2095\u20132128.","journal-title":"Lancet"},{"key":"BFijo201622_CR2","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1016\/S0140-6736(04)17018-9","volume":"364","author":"S Yusuf","year":"2004","unstructured":"Yusuf S, Hawken S, \u00d4unpuu S, Dans T, Avezum A, Lanas F et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004; 364: 937\u2013952.","journal-title":"Lancet"},{"key":"BFijo201622_CR3","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1097\/MOP.0b013e3280208519","volume":"19","author":"JM Saland","year":"2007","unstructured":"Saland JM . Update on the metabolic syndrome in children. Curr Opin Pediatr 2007; 19: 183\u2013191.","journal-title":"Curr Opin Pediatr"},{"key":"BFijo201622_CR4","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/pr.2012.158","volume":"73","author":"A Bugge","year":"2013","unstructured":"Bugge A, El-Naaman B, McMurray RG, Froberg K, Andersen LB . Tracking of clustered cardiovascular disease risk factors from childhood to adolescence. Pediatr Res 2013; 73: 245\u2013249.","journal-title":"Pediatr Res"},{"key":"BFijo201622_CR5","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1186\/1741-7015-11-172","volume":"11","author":"D Jim\u00e9nez-Pav\u00f3n","year":"2013","unstructured":"Jim\u00e9nez-Pav\u00f3n D, Konstabel K, Bergman P, Ahrens W, Pohlabeln H, Hadjigeorgiou C et alIDEFICS consortium.. Physical activity and clustered cardiovascular disease risk factors in young children: a cross-sectional study (the IDEFICS study). BMC Med 2013; 11: 172.","journal-title":"BMC Med"},{"key":"BFijo201622_CR6","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1111\/j.1399-5448.2011.00769.x","volume":"12","author":"EG Artero","year":"2011","unstructured":"Artero EG, Ruiz JR, Ortega FB, Espana-Romero V, Vicente-Rodriguez G, Molnar D et al. Muscular and cardiorespiratory fitness are independently associated with metabolic risk in adolescents: the HELENA study. Pediatr Diabetes 2011; 12: 704\u2013712.","journal-title":"Pediatr Diabetes"},{"key":"BFijo201622_CR7","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1249\/MSS.0b013e31819aaae5","volume":"41","author":"J Steene-Johannessen","year":"2009","unstructured":"Steene-Johannessen J, Anderssen SA, Kolle E, Andersen LB . Low muscle fitness is associated with metabolic risk in youth. Med Sci Sports Exerc 2009; 41: 1361\u20131367.","journal-title":"Med Sci Sports Exerc"},{"key":"BFijo201622_CR8","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1136\/bjsm.2008.056499","volume":"43","author":"JR Ruiz","year":"2009","unstructured":"Ruiz JR, Castro-Pinero J, Artero EG, Ortega FB, Sj\u00f6str\u00f6m M, Suni J et al. Predictive validity of health-related fitness in youth: a systematic review. Br J Sports Med 2009; 43: 909\u2013923.","journal-title":"Br J Sports Med"},{"key":"BFijo201622_CR9","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1080\/17477160600962864","volume":"1","author":"AC Benson","year":"2006","unstructured":"Benson AC, Torode ME, Singh MA . Muscular strength and cardiorespiratory fitness is associated with higher insulin sensitivity in children and adolescents. Int J Pediatr Obes 2006; 1: 222\u2013231.","journal-title":"Int J Pediatr Obes"},{"key":"BFijo201622_CR10","doi-asserted-by":"publisher","first-page":"e93150","DOI":"10.1371\/journal.pone.0093150","volume":"9","author":"DD Cohen","year":"2014","unstructured":"Cohen DD, G\u00f3mez-Arbel\u00e1ez D, Camacho PA, Pinzon S, Hormiga C, Trejos-Suarez J et al. Low muscle strength is associated with metabolic risk factors in Colombian children: the ACFIES study. PLoS One 2014; 9: e93150.","journal-title":"PLoS One"},{"key":"BFijo201622_CR11","doi-asserted-by":"publisher","first-page":"2143","DOI":"10.2337\/dc07-0734","volume":"30","author":"I Janssen","year":"2007","unstructured":"Janssen I, Cramp W . Cardiorespiratory fitness is strongly related to the metabolic syndrome in adolescents. Diabetes Care 2007; 30: 2143\u20132144.","journal-title":"Diabetes Care"},{"key":"BFijo201622_CR12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1479-5868-1-6","volume":"1","author":"LB Andersen","year":"2004","unstructured":"Andersen LB, Hasselstrom H, Gronfeldt V, Hansen SE, Karsten F . The relationship between physical fitness and clustered risk, and tracking of clustered risk from adolescence to young adulthood: eight years follow-up in the Danish Youth and Sport Study. Int J Behav Nutr Phys Act 2004; 1: 6.","journal-title":"Int J Behav Nutr Phys Act"},{"key":"BFijo201622_CR13","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1093\/eurpub\/cki196","volume":"16","author":"G Psarra","year":"2006","unstructured":"Psarra G, Nassis GP, Sidossis LS . Short-term predictors of abdominal obesity in children. Eur J Public Health 2006; 16: 520\u2013525.","journal-title":"Eur J Public Health"},{"key":"BFijo201622_CR14","doi-asserted-by":"publisher","first-page":"S15","DOI":"10.1055\/s-2002-28456","volume":"23","author":"KF Janz","year":"2002","unstructured":"Janz KF, Dawson JD, Mahoney LT . Increases in physical fitness during childhood improve cardiovascular health during adolescence: the Muscatine Study. Int J Sports Med 2002; 23: S15\u2013S21.","journal-title":"Int J Sports Med"},{"key":"BFijo201622_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/sj.ijo.0803774","volume":"32","author":"F Ortega","year":"2008","unstructured":"Ortega F, Ruiz J, Castillo M, Sj\u00f6str\u00f6m M . Physical fitness in childhood and adolescence: a powerful marker of health. Int J Obes 2008; 32: 1\u201311.","journal-title":"Int J Obes"},{"key":"BFijo201622_CR16","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1007\/s40279-014-0196-4","volume":"44","author":"JJ Smith","year":"2014","unstructured":"Smith JJ, Eather N, Morgan PJ, Plotnikoff RC, Faigenbaum AD, Lubans DR . The health benefits of muscular fitness for children and adolescents: a systematic review and meta-analysis. Sports Med 2014; 44: 1209\u20131223.","journal-title":"Sports Med"},{"key":"BFijo201622_CR17","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1157\/13107114","volume":"60","author":"E Garcia-Artero","year":"2007","unstructured":"Garcia-Artero E, OrtegaFB, RuizJR, Mesa JL, Delgado M, Gonz\u00e1lez-Gross M et al. Lipid and metabolic profiles in adolescents are affected more by physical fitness than physical activity (AVENA study). Rev Esp Cardiol 2007; 60: 581\u2013588.","journal-title":"Rev Esp Cardiol"},{"key":"BFijo201622_CR18","doi-asserted-by":"publisher","first-page":"3092","DOI":"10.1001\/jama.290.23.3092","volume":"290","author":"MR Carnethon","year":"2003","unstructured":"Carnethon MR, Gidding SS, Nehgme R, Sidney S, Jacobs Jr DR, Liu K . Cardiorespiratory fitness in young adulthood and the development of cardiovascular disease risk factors. JAMA 2003; 290: 3092\u20133100.","journal-title":"JAMA"},{"key":"BFijo201622_CR19","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1038\/sj.ijo.0803448","volume":"31","author":"M Brunet","year":"2006","unstructured":"Brunet M, Chaput JP, Tremblay A . The association between low physical fitness and high body mass index or waist circumference is increasing with age in children: the 'Quebec en Forme' Project. Int J Obes (Lond) 2006; 31: 637\u2013645.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR20","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1097\/HJR.0b013e328011efc1","volume":"14","author":"SA Anderssen","year":"2007","unstructured":"Anderssen SA, Cooper AR, Riddoch C, Sardinha LB, Harro M, Brage S et al. Low cardiorespiratory fitness is a strong predictor for clustering of cardiovascular disease risk factors in children independent of country, age and sex. Eur J Cardiovasc Prev Rehabil 2007; 14: 526\u2013531.","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"BFijo201622_CR21","first-page":"1401","volume":"50","author":"JR Ruiz","year":"2007","unstructured":"Ruiz JR, Rizzo NS, Ortega FB, Loit HM, Veidebaum T, Sjostrom M . Markers of insulin resistance are associated with fatness and fitness in school-aged children: the European Youth Heart Study. Int J Obes (Lond) 2007; 50: 1401\u20131408.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR22","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1038\/ijo.2011.30","volume":"35","author":"W Ahrens","year":"2011","unstructured":"Ahrens W, Bammann K, Siani A, Buchecker K, De Henauw S, Iacoviello L et al. The IDEFICS cohort: design, characteristics and participation in the baseline survey. Int J Obes (Lond) 2011; 35: S3\u201315.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR23","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.numecd.2006.01.011","volume":"16","author":"W Ahrens","year":"2006","unstructured":"Ahrens W, Bammann K, de Henauw S, Halford J, Palou A, Pigeot I et al. Understanding and preventing childhood obesity and related disorders-IDEFICS: a European multilevel epidemiological approach. Nutr Metab Cardiovasc Dis 2006; 16: 302\u2013308.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"BFijo201622_CR24","unstructured":"Council of Europe Committee for the Development of Sport. Eurofit: Handbook for the EUROFIT Tests of Physical Fitness. Rome, Italy: Edigraf editoriale grafica,1988."},{"key":"BFijo201622_CR25","doi-asserted-by":"publisher","first-page":"S30","DOI":"10.1038\/ijo.2011.33","volume":"35","author":"M Suling","year":"2011","unstructured":"Suling M, Hebestreit A, Peplies J, Bammann K, Nappo A, Eiben G et al. Design and results of the pretest of the IDEFICS study. Int J Obes (Lond) 2011; 35: S30\u2013S44.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR26","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1136\/bjsm.2010.075341","volume":"45","author":"JR Ruiz","year":"2011","unstructured":"Ruiz JR, Castro-Pinero J, Espana-Romero V, Artero EG, Ortega FB, Cuenca MM et al. Field-based fitness assessment in young people: the ALPHA health-related fitness test battery for children and adolescents. Br J Sports Med 2011; 45: 518\u2013524.","journal-title":"Br J Sports Med"},{"key":"BFijo201622_CR27","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1055\/s-0030-1268488","volume":"32","author":"EG Artero","year":"2011","unstructured":"Artero EG, Espana-Romero V, Castro-Pinero J, Ortega FB, Suni J, Castillo-Garzon MJ et al. Reliability of field-based fitness tests in youth. Int J Sports Med 2011; 32: 159\u2013169.","journal-title":"Int J Sports Med"},{"key":"BFijo201622_CR28","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1080\/02640418808729800","volume":"6","author":"LA Leger","year":"1988","unstructured":"Leger LA, Mercier D, Gadoury C, Lambert J et al. The multistage 20 meter shuttle run test for aerobic fitness. J Sports Sci 1988; 6: 93\u2013101.","journal-title":"J Sports Sci"},{"key":"BFijo201622_CR29","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.jhsa.2007.11.013","volume":"33","author":"V Espa\u00f1a-Romero","year":"2008","unstructured":"Espa\u00f1a-Romero V, Artero EG, Santaliestra-Pasias AM, Gutierrez A, Castillo MJ, Ruiz JR . Hand span influences optimal grip span in boys and girls aged 6 to 12 years. J Hand Surg Am 2008; 33: 378\u2013384.","journal-title":"J Hand Surg Am"},{"key":"BFijo201622_CR30","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1519\/JSC.0b013e3181ddb03d","volume":"24","author":"J Castro-Pinero","year":"2010","unstructured":"Castro-Pinero J, Ortega FB, Artero EG, Girela-Rej\u00f3n MJ, Mora J, Sj\u00f6str\u00f6m M et al. Assessing muscular strength in youth: usefulness of standing long jump as a general index of muscular fitness. J Strength Cond Res 2010; 24: 1810\u20131817.","journal-title":"J Strength Cond Res"},{"key":"BFijo201622_CR31","volume-title":"Fitnessgram-Activitygram Test Administration Manual","author":"M Meredith","year":"2007","unstructured":"Meredith M, Welk G . Fitnessgram-Activitygram Test Administration Manual. Human Kinetics: Champaign: IL, USA, 2007."},{"key":"BFijo201622_CR32","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1038\/ijo.2014.130","volume":"38","author":"W Ahrens","year":"2014","unstructured":"Ahrens W, Moreno LA, M\u00e5rild S, Moln\u00e1r D, Siani A, De Henauw S et al. IDEFICS consortium. Metabolic syndrome in young children: definitions and results of the IDEFICS study. Int J Obes (Lond) 2014; 38: S4\u2013S14.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR33","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1097\/MBP.0b013e3282c9abf7","volume":"12","author":"BS Alpert","year":"2007","unstructured":"Alpert BS . Validation of the Welch Allyn spot vital signs blood pressure device according to the ANSI\/AAMI SP10: 2002. Accuracy and cost-efficiency successfully combined. Blood Press Monit 2007; 12: 345\u2013347.","journal-title":"Blood Press Monit"},{"key":"BFijo201622_CR34","doi-asserted-by":"publisher","first-page":"S48","DOI":"10.1038\/ijo.2014.135","volume":"38","author":"G Barba","year":"2014","unstructured":"Barba G, Buck C, Bammann K, Hadjigeorgiou C, Hebestreit A, M\u00e5rild S et al. Blood pressure reference values for European non-overweight schoolchildren: the IDEFICS study. Int J Obes (Lond) 2014; 38: S48\u2013S56.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR35","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1542\/peds.114.2.S2.555","volume":"114","author":"National Blood Pressure Education Working Group on High Blood Pressure in Children and Adolescents","year":"2004","unstructured":"National Blood Pressure Education Working Group on High Blood Pressure in Children and Adolescents. The Fourth report on the diagnosis, evaluation and treatment of high blood pressure in children and adolescents: a working group report from the National High Blood Pressure Education Program. Pediatrics 2004; 114: 555\u2013576.","journal-title":"Pediatrics"},{"key":"BFijo201622_CR36","first-page":"112","volume":"16","author":"VR Panz","year":"2005","unstructured":"Panz VR, Raal FJ, Paiker J, Immelman R, Miles H . Performance of the Cardio Chek PA and Cholestech LDX point-of-care analysers compared to clinical diagnostic laboratory methods for the measurement of lipids. Cardiovasc J S Afr 2005; 16: 112\u2013117.","journal-title":"Cardiovasc J S Afr"},{"key":"BFijo201622_CR37","doi-asserted-by":"publisher","first-page":"S104","DOI":"10.1038\/ijo.2011.41","volume":"35","author":"J Peplies","year":"2011","unstructured":"Peplies J, Guenther K, Bammann K, Fraterman A, Russo P, Veidebaum T et al. On behalf of the IDEFICS consortium. Influence of sample collection and preanalytical sample processing on the analyses of biological markers in the European multicentre study IDEFICS. Int J Obes (Lond) 2011; 35: S104\u2013S112.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR38","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1007\/BF00280883","volume":"28","author":"DR Matthews","year":"1985","unstructured":"Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412\u2013419.","journal-title":"Diabetologia"},{"key":"BFijo201622_CR39","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/j.2047-6310.2012.00064.x","volume":"7","author":"TJ Cole","year":"2012","unstructured":"Cole TJ, Lobstein T . Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity. Pediatr Obes 2012; 7: 284\u2013294.","journal-title":"Pediatr Obes"},{"key":"BFijo201622_CR40","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1038\/ijo.2011.164","volume":"36","author":"A Lanfer","year":"2012","unstructured":"Lanfer A, Knof K, Barba G, Veidebaum T, Papoutsou S, de Henauw S et al. Taste preferences in association with dietary habits and weight status in European children: results from the IDEFICS study. Int J Obes (Lond) 2012; 36: 27\u201334.","journal-title":"Int J Obes (Lond)"},{"key":"BFijo201622_CR41","doi-asserted-by":"publisher","first-page":"S98","DOI":"10.1038\/ijo.2011.40","volume":"35","author":"R Ojiambo","year":"2011","unstructured":"Ojiambo R, Cuthill R, Budd H, Konstabel K, Casaj\u00fas JA, Gonz\u00e1lez-Ag\u00fcero A et al. Impact of methodological decisions on accelerometer outcome variables in young children. Int J Obes 2011; 35: S98\u2013S103.","journal-title":"Int J Obes"},{"key":"BFijo201622_CR42","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1080\/02640410802334196","volume":"26","author":"KR Evenson","year":"2008","unstructured":"Evenson KR, Catellier DJ, Gill K, Ondrak KS, McMurray RG . Calibration of two objective measures of physical activity for children. J Sports Sci 2008; 26: 1557\u20131565.","journal-title":"J Sports Sci"},{"key":"BFijo201622_CR43","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3109\/17477166.2011.606816","volume":"6","author":"LB Andersen","year":"2011","unstructured":"Andersen LB, Bugge A, Dencker M, Eiberg S, El-Naaman B . The association between physical activity, physical fitness and development of metabolic disorders. Int J Pediatr Obes 2011; 6: 29\u201334.","journal-title":"Int J Pediatr Obes"},{"key":"BFijo201622_CR44","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1111\/j.1600-0838.2009.00959.x","volume":"20","author":"EG Artero","year":"2010","unstructured":"Artero EG, Espa\u00f1a-Romero V, Ortega FB, Jim\u00e9nez-Pav\u00f3n D, Ruiz JR, Vicente-Rodr\u00edguez G et al. Health-related fitness in adolescents: underweight, and not only overweight, as an influencing factor. The AVENA study. Scand J Med Sci Sports 2010; 20: 418\u2013427.","journal-title":"Scand J Med Sci Sports"},{"key":"BFijo201622_CR45","unstructured":"US Dept of Health and Human Services Physical Activity Guidelines for Americans. US Dept of Health and Human Services: Washington, USA, 2008."},{"key":"BFijo201622_CR46","first-page":"119","volume":"28","author":"DN Ardoy","year":"2013","unstructured":"Ardoy DN, Artero EG, Ruiz JR, Labayen I, Sj\u00f6str\u00f6m M, Castillo MJ et al. Effects on adolescents' lipid profile of a fitness-enhancing intervention in the school setting; the EDUFIT study. Nutr Hosp 2013; 28: 119\u2013126.","journal-title":"Nutr Hosp"},{"key":"BFijo201622_CR47","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1097\/HJR.0b013e3282fb2df1","volume":"15","author":"C Walther","year":"2008","unstructured":"Walther C, Adams V, Bothur I, Drechsler K, Fikenzer S, Sonnabend M et al. Increasing physical education in highschool students: effects on concentration of circulating endothelial progenitor cells. Eur J Cardiovasc Prev Rehabil 2008; 15: 416\u2013422.","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"BFijo201622_CR48","doi-asserted-by":"publisher","first-page":"c785","DOI":"10.1136\/bmj.c785","volume":"340","author":"S Kriemler","year":"2010","unstructured":"Kriemler S, Zahner L, Schindler C, Meyer U, Hartmann T, Hebestreit H et al. Effect of school based physical activity programme (KISS) on fitness and adiposity in primary schoolchildren: cluster randomised controlled trial. BMJ 2010; 340: c785.","journal-title":"BMJ"},{"key":"BFijo201622_CR49","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1123\/pes.6.4.361","volume":"6","author":"B Alpert","year":"1994","unstructured":"Alpert B, Wilmore JH . Physical activity and blood pressure in adolescents. Pediatr Exerc Sci 1994; 6: 361\u2013380.","journal-title":"Pediatr Exerc Sci"},{"key":"BFijo201622_CR50","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1037\/0022-006X.58.2.237","volume":"58","author":"JS Danforth","year":"1990","unstructured":"Danforth JS, Allen KD, Fitterling JM, Danforth JA, Farrar D, Brown M et al. Exercise as a treatment for hypertension in low-socioeconomic-status black children. J Consult Clin Psychol 1990; 58: 237\u2013239.","journal-title":"J Consult Clin Psychol"},{"key":"BFijo201622_CR51","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1136\/bmj.303.6804.682","volume":"303","author":"HS Hansen","year":"1991","unstructured":"Hansen HS, Froberg K, Hyldebrandt N, Nielsen JR . A controlled study of eight months of physical training and reduction of blood pressure in children: the Odense schoolchild study. BMJ 1991; 303: 682\u2013685.","journal-title":"BMJ"},{"key":"BFijo201622_CR52","first-page":"139","volume":"3","author":"B Torrance","year":"2007","unstructured":"Torrance B, McGuire KA, Lewanczuk R, McGavock J . Overweight, physical activity and high blood pressure in children: a review of the literature. Vasc Health Risk Manag 2007; 3: 139\u2013149.","journal-title":"Vasc Health Risk Manag"},{"key":"BFijo201622_CR53","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1097\/00005768-200008000-00014","volume":"32","author":"JW Twisk","year":"2000","unstructured":"Twisk JW, Kemper HC, van Mechelen W . Tracking of activity and fitness and the relationship with cardiovascular disease risk factors. Med Sci Sports Exerc 2000; 32: 1455\u20131461.","journal-title":"Med Sci Sports Exerc"},{"key":"BFijo201622_CR54","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1210\/jc.2006-1516","volume":"92","author":"M Rosenbaum","year":"2007","unstructured":"Rosenbaum M, Nonas C, Weil R, Horlick M, Fennoy I, Vargas I et al. School-based intervention acutely improves insulinsensitivity and decreases inflammatory markers and body fatness in junior high school students. J Clin Endocrinol Metab 2007; 92: 504\u2013508.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFijo201622_CR55","doi-asserted-by":"publisher","first-page":"868305","DOI":"10.1155\/2011\/868305","volume":"2011","author":"SH Boutcher","year":"2011","unstructured":"Boutcher SH . High-intensity intermittent exercise and fat loss. J Obes 2011; 2011: 868305.","journal-title":"J Obes"},{"key":"BFijo201622_CR56","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1542\/peds.34.3.308","volume":"34","author":"GB Forbes","year":"1964","unstructured":"Forbes GB . Lean body mass and fat in obese children. Pediatrics 1964; 34: 308\u2013314.","journal-title":"Pediatrics"},{"key":"BFijo201622_CR57","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1136\/bjsm.2009.062430","volume":"45","author":"D Moliner-Urdiales","year":"2011","unstructured":"Moliner-Urdiales D . Associations of muscular and cardiorespiratory fitness with total and central body fat in adolescents: the HELENA Study. Br J Sports Med 2011; 45: 101\u2013108.","journal-title":"Br J Sports Med"},{"key":"BFijo201622_CR58","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/j.1550-8528.1995.tb00142.x","volume":"3","author":"RM Malina","year":"1995","unstructured":"Malina RM, Beunen GP, Classens AL, Lefevre J, Vanden Eynde BV, Renson R et al. Fatness and physical fitness of girls 7 to 17 years. Obes Res 1995; 3: 221\u2013231.","journal-title":"Obes Res"},{"key":"BFijo201622_CR59","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1038\/oby.2003.59","volume":"11","author":"B Deforche","year":"2003","unstructured":"Deforche B, Lefevre J, De Bourdeaudhuij I, Hills AP, Duquet W, Bouckaert J et al. Physical fitness and physical activity in obese and nonobese Flemish youth. Obes Res 2003; 11: 434\u2013441.","journal-title":"Obes Res"},{"key":"BFijo201622_CR60","doi-asserted-by":"publisher","first-page":"2455","DOI":"10.1007\/s00421-011-2216-5","volume":"112","author":"D Jim\u00e9nez-Pav\u00f3n","year":"2012","unstructured":"Jim\u00e9nez-Pav\u00f3n D, Ortega FB, Valtue\u00f1a J, Castro-Pi\u00f1ero J, G\u00f3mez-Mart\u00ednez S, Zaccaria M et al. Muscular strength and markers of insulin resistance in European adolescents: the HELENA Study. Eur J Appl Physiol 2012; 112: 2455\u20132465.","journal-title":"Eur J Appl Physiol"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/ijo201622.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo201622","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ijo201622.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T19:19:20Z","timestamp":1647371960000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ijo201622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,9]]},"references-count":60,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["BFijo201622"],"URL":"https:\/\/doi.org\/10.1038\/ijo.2016.22","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,9]]},"assertion":[{"value":"9 July 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2015","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2015","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2016","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}