{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T07:39:30Z","timestamp":1777793970771,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1988,10,1]],"date-time":"1988-10-01T00:00:00Z","timestamp":591667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[1988,10]]},"abstract":"\n The photoelectric method using carbon black as a nondiffusible tracer of blood was compared with the hydrogen clearance (H\n 2<\/jats:sub>\n ) method in nine anesthetized cats. A photoelectric apparatus and H\n 2<\/jats:sub>\n electrode were applied to a small region of the cerebral cortex (left ectosylvian gyrus) for simultaneous measurement of the regional CBF. The values of CBF(H\n 2<\/jats:sub>\n ) and CBF(photoelectric) were 50.7 \u00b1 19.2 and 52.1 \u00b1 14.5 ml \u2212 100 g\n \u22121<\/jats:sup>\n \u00b7 min\n \u22121<\/jats:sup>\n , respectively. CBF(H\n 2<\/jats:sub>\n ) and CBF(photoelectric) were found to correlate well ( r = 0.588, p < 0.01) when changes in CBF were induced by CO\n 2<\/jats:sub>\n inhalation, exsanguination, hyperventilation, and occlusion of the middle cerebral artery. The correlation between CBF(H2) and CBF(photoelectric) was much better in the case of intraindividual comparisons ( r = 0.957, p < 0.01). In addition to its merits in common with the H\n 2<\/jats:sub>\n clearance method, such as handiness, low cost, and strict regionality, the photoelectric method displayed the following advantages: time-to-time measurements of CBF (<20 s), immediate display of the microcirculatory flow pattern, and simultaneous monitoring of cerebral blood volume. However, measurements from deep structures of the brain are better performed by the H\n 2<\/jats:sub>\n method despite the disadvantage of the use of a potentially explosive gas.\n <\/jats:p>","DOI":"10.1038\/jcbfm.1988.120","type":"journal-article","created":{"date-parts":[[2011,4,8]],"date-time":"2011-04-08T13:42:49Z","timestamp":1302270169000},"page":"727-732","source":"Crossref","is-referenced-by-count":19,"title":["Comparison between the Photoelectric Method and H\n 2<\/sub>\n Clearance Method for Measuring Cerebrocortical Blood Flow in Cats"],"prefix":"10.1177","volume":"8","author":[{"given":"Minora","family":"Tomita","sequence":"first","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumio","family":"Gotoh","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Tanahashi","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Kobari","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Terayama","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ban","family":"Mihara","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichi","family":"Ohta","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Gerdsen","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Keio University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1988,10,1]]},"reference":[{"key":"bibr1-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1965.tb01951.x"},{"key":"bibr2-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.1981.11739590"},{"key":"bibr3-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.51.3.261"},{"key":"bibr4-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1007\/BF00235437"},{"key":"bibr5-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1966.00470170103013"},{"key":"bibr6-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1214\/aoms\/1177729885"},{"key":"bibr7-jcbfm.1988.120","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.1.91"},{"key":"bibr8-jcbfm.1988.120","first-page":"218","volume":"24","author":"Kobari M","year":"1982","journal-title":"Microvasc 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