{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:37:22Z","timestamp":1791092242105,"version":"4.1.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2008,4,30]],"date-time":"2008-04-30T00:00:00Z","timestamp":1209513600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p>\n                    Neurogenesis occurs in discrete regions of normal brains of adult mammals including humans, and is induced in response to brain injury and neurodegenerative disease. Whether intracerebral hemorrhage can also induce neurogenesis in human brain is unknown. Specimens were obtained from patients with primary intracerebral hemorrhage undergoing surgical evacuation of an intracerebral hematoma, and evaluated by two-photon laser scanning confocal microscopy. We found that neural stem\/progenitor cell-specific protein markers were expressed in cells located in the perihematomal regions of the basal ganglia and parietal lobe of the adult human brain after primary intracerebral hemorrhage (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 5). Cells in this region also expressed cell proliferation markers, which colocalized to the same cells that expressed neural stem\/progenitor cell-specific proteins. Our data suggest that intracerebral hemorrhage induces neurogenesis in the adult human brain.\n                  <\/jats:p>","DOI":"10.1038\/jcbfm.2008.37","type":"journal-article","created":{"date-parts":[[2008,4,30]],"date-time":"2008-04-30T04:09:03Z","timestamp":1209528543000},"page":"1460-1468","source":"Crossref","is-referenced-by-count":62,"title":["Neurogenesis after Primary Intracerebral Hemorrhage in Adult Human Brain"],"prefix":"10.1177","volume":"28","author":[{"given":"Jianfeng","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, First Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Xie","sequence":"additional","affiliation":[{"name":"Buck Institute for Age Research, Novato, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiaoOu","family":"Mao","sequence":"additional","affiliation":[{"name":"Buck Institute for Age Research, Novato, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, First Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renya","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, First Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Buck Institute for Age Research, Novato, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunlin","family":"Jin","sequence":"additional","affiliation":[{"name":"Buck Institute for Age Research, Novato, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,4,30]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.5530130307"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm747"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.4.905"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/3305"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.1999.00459.x"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80777-1"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.133.4.1710"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.20434"},{"key":"e_1_3_2_10_1","first-page":"I94","article-title":"Treatment of spontaneous intracerebral and intracerebellar hemorrhages","volume":"24","author":"Heiskanen O","year":"1993","unstructured":"Heiskanen O (1993) Treatment of spontaneous intracerebral and intracerebellar hemorrhages. 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