{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T16:40:11Z","timestamp":1741106411267,"version":"3.38.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2011,3,17]],"date-time":"2011-03-17T00:00:00Z","timestamp":1300320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hum Genet"],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.1038\/jhg.2011.24","type":"journal-article","created":{"date-parts":[[2011,3,17]],"date-time":"2011-03-17T07:09:20Z","timestamp":1300345760000},"page":"383-389","source":"Crossref","is-referenced-by-count":2,"title":["Exploration of the disease locus by a careful evaluation of the likelihood polynomial for pedigree data"],"prefix":"10.1038","volume":"56","author":[{"given":"Yuki","family":"Sugaya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritei","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,3,17]]},"reference":[{"key":"BFjhg201124_CR1","first-page":"115","volume-title":"The 52nd Annual Meeting of the Japan Society of Human Genetics","author":"Y Sugaya","year":"2007","unstructured":"Sugaya, Y. & Shibata, R. Probability inheritance algorithm and its application. The 52nd Annual Meeting of the Japan Society of Human Genetics, The Japan Society of Human Genetics, Tokyo, Japan, 115 (2007)."},{"key":"BFjhg201124_CR2","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1002\/1098-2272(200012)19:4<366::AID-GEPI8>3.0.CO;2-F","volume":"19","author":"EW Daw","year":"2000","unstructured":"Daw, E. W., Thompson, E. A. & Wijsman, E. M. Bias in multipoint linkage analysis arising from map misspecification. Genet. Epidemiol. 19, 366\u2013380 (2000).","journal-title":"Genet. Epidemiol."},{"key":"BFjhg201124_CR3","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1017\/S0016672301005389","volume":"79","author":"R Wu","year":"2002","unstructured":"Wu, R., Xing, M. C., Wu, S. S. & Zeng, Z. B. Linkage mapping of sex-specific differences. Genet. Res. 79, 85\u201396 (2002).","journal-title":"Genet. Res."},{"key":"BFjhg201124_CR4","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1159\/000077547","volume":"57","author":"B Feenstra","year":"2004","unstructured":"Feenstra, B., Greenberg, D. A. & Hodge, S. E. Using LOD scores to detect sex differences in male-female recombination fractions. Hum. Hered. 57, 100\u2013108 (2004).","journal-title":"Hum. Hered."},{"key":"BFjhg201124_CR5","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1002\/gepi.20151","volume":"30","author":"TE Fingerlin","year":"2006","unstructured":"Fingerlin, T. E., Abecasis, G. R. & Boehnke, M. Using sex-average genetic maps in multipoint linkage analysis when identity-by-decent status is incompletely known. Genet. Epidemiol. 30, 384\u2013396 (2006).","journal-title":"Genet. Epidemiol."},{"key":"BFjhg201124_CR6","first-page":"85","volume":"12","author":"CP Pang","year":"2006","unstructured":"Pang, C. P., Fan, B. J., Canlas, O., Wang, D. Y., Dubois, S., Tam, P. O. et al. A genome-wide scan maps a novel juvenile-onset primary open angle glaucoma locus to chromosome 5q. Mol. Vis. 12, 85\u201392 (2006).","journal-title":"Mol. Vis."},{"key":"BFjhg201124_CR7","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1002\/1529-0131(200004)43:4<925::AID-ANR26>3.0.CO;2-B","volume":"43","author":"N Kamatani","year":"2000","unstructured":"Kamatani, N., Moritani, M., Yamanaka, H., Takeuchi, F., Hosoya, T. & Itakura, M. Localization of a gene for familial juvenile hyperuricemic nephropathy causing underexcretion-type gout to 16p12 by genome-wide linkage analysis of a large family. Arthritis Rheum. 43, 925\u2013929 (2000).","journal-title":"Arthritis Rheum."},{"key":"BFjhg201124_CR8","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1136\/jmg.39.12.882","volume":"39","author":"TC Hart","year":"2002","unstructured":"Hart, T. C., Gorry, M. C., Hart, P. S., Woodard, A. S., Shihabi, Z., Sandhu, J. et al. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J. Med. Genet. 39, 882\u2013892 (2002).","journal-title":"J. Med. Genet."},{"key":"BFjhg201124_CR9","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1111\/j.1523-1755.2004.00559.x","volume":"65","author":"E Kudo","year":"2004","unstructured":"Kudo, E., Kamatani, N., Tezuka, O., Taniguchi, A., Yamanaka, H., Yabe, S. et al. Familial juvenile hyperuricemic nephropathy: detection of mutations in the uromodulin gene in five Japanese families. Kidney Int. 65, 1589\u20131597 (2004).","journal-title":"Kidney Int."},{"key":"BFjhg201124_CR10","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1159\/000152448","volume":"21","author":"RC Elston","year":"1971","unstructured":"Elston, R. C. & Stewart, J. A general model for the genetic analysis of pedigree data. Hum. Hered. 21, 523\u2013542 (1971).","journal-title":"Hum. Hered."},{"key":"BFjhg201124_CR11","first-page":"588","volume":"26","author":"J Ott","year":"1974","unstructured":"Ott, J. Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage study. Am. J. Hum. Genet. 26, 588\u2013597 (1974).","journal-title":"Am. J. Hum. Genet."},{"key":"BFjhg201124_CR12","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1159\/000152714","volume":"25","author":"K Lange","year":"1975","unstructured":"Lange, K. & Elston, R. C. Extensions to pedigree analysis. Hum. Hered. 25, 95\u2013105 (1975).","journal-title":"Hum. Hered."},{"key":"BFjhg201124_CR13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.2307\/1426718","volume":"10","author":"C Cannings","year":"1978","unstructured":"Cannings, C., Thompson, E. A. & Skolnick, M. H. Probability functions on complex pedigrees. Appl. Prob. 10, 26\u201361 (1978).","journal-title":"Appl. Prob."},{"key":"BFjhg201124_CR14","first-page":"2363","volume":"84","author":"ES Lander","year":"1987","unstructured":"Lander, E. S. & Green, P. Construction of multilocus genetic linkage maps in humans. Genetics 84, 2363\u20132367 (1987).","journal-title":"Genetics"},{"key":"BFjhg201124_CR15","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1093\/bioinformatics\/18.suppl_1.S189","volume":"18","author":"M Fishelson","year":"2002","unstructured":"Fishelson, M. & Geiger, D. Exact genetic linkage computations for general pedigrees. Bioinfomatics 18, 189\u2013198 (2002).","journal-title":"Bioinfomatics"},{"key":"BFjhg201124_CR16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.2517-6161.1991.tb01806.x","volume":"53","author":"A Thomas","year":"1991","unstructured":"Thomas, A. Gene hunting with gradients of likelihoods. J. R. Statist. Soc. B 53, 3\u201326 (1991).","journal-title":"J. R. Statist. Soc. B"},{"key":"BFjhg201124_CR17","unstructured":"Sibson, R. CONICON 3 handbook ( University of Bath 1987)."},{"key":"BFjhg201124_CR18","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1093\/hmg\/ddi068","volume":"14","author":"S Monemi","year":"2005","unstructured":"Monemi, S., Spaeth, G., Dasilva, A., Popinchalk, S., Illitchev, E., Liebmann, J. et al. Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1. Hum. Mol. Genet. 14, 725\u2013733 (2005).","journal-title":"Hum. Mol. Genet."}],"container-title":["Journal of Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/jhg201124.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/jhg201124","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/jhg201124.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T15:44:34Z","timestamp":1741103074000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jhg201124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,17]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["BFjhg201124"],"URL":"https:\/\/doi.org\/10.1038\/jhg.2011.24","relation":{},"ISSN":["1434-5161","1435-232X"],"issn-type":[{"type":"print","value":"1434-5161"},{"type":"electronic","value":"1435-232X"}],"subject":[],"published":{"date-parts":[[2011,3,17]]}}}